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PROSITE entry PS00895


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00895
Entry name [info] 3_HYDROXYISOBUT_DH
Accession [info] PS00895
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00697

Name and characterization of the entry

Description [info] 3-hydroxyisobutyrate dehydrogenase signature.
Pattern [info] 
[LIVMFY](2)-G-L-G-x-[MQ]-G-x(2)-[MA]-[SAV]-x-[SNHR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 34 in 34 different sequences
Number of true positive hits 32 in 32 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 94.12 %
Recall (true positives / (true positives + false negatives)) 62.75 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 32 sequences 

3HIDH_ARATH (Q9SUC0), 3HIDH_CAEEL (Q9XTI0), 3HIDH_DROME (Q9V8M5), 

3HIDH_HUMAN (P31937), 3HIDH_MOUSE (Q99L13), 3HIDH_PONAB (Q5R5E7), 
3HIDH_RABIT (P32185), 3HIDH_RAT   (P29266), FHMCD_RHILO (Q988C8), 
GARR_ECOL6  (P0ABQ3), GARR_ECOLI  (P0ABQ2), GLXR_ECOLI  (P77161), 
GLYR1_AEDAE (Q175F8), GLYR1_ARATH (Q9LSV0), HMGD_EUBBA  (Q0QLF5), 
LTND_ECOL6  (A0A0H2VA68), LTND_ECOLI  (Q46888), LTND_HAEIN  (P44979), 
LTND_PECAS  (Q6CZ26), MMSB_MYCBO  (P63936), MMSB_MYCTO  (P9WNY4), 
MMSB_MYCTU  (P9WNY5), MMSB_PSEAE  (P28811), SERDH_PSEAE (Q9I5I6), 
SQUU_ECOLI  (P0A9V8), SQUU_SALTY  (Q9L7S0), SQUU_SHIFL  (P0A9V9), 
Y1503_SHEFN (O33730), Y229_SYNY3  (Q55702), Y770_MYCTO  (P9WNY2), 
Y770_MYCTU  (P9WNY3), YKWC_BACSU  (O34948)
» more

UniProtKB/Swiss-Prot
False negative sequences		 19 sequences 

3HID1_ARATH (Q9SZE1), 3HID2_ARATH (Q9C991), 3HID3_ARATH (Q949M8), 

3HIDH_BOVIN (Q2HJD7), 3HIDH_DICDI (Q54CX6), GLYR1_ANOGA (Q7Q161), 
GLYR1_BOVIN (A4FUF0), GLYR1_CHICK (Q5ZLS7), GLYR1_DANRE (Q5RKN4), 
GLYR1_DROME (Q8T079), GLYR1_DROPS (Q29NG1), GLYR1_HUMAN (Q49A26), 
GLYR1_MOUSE (Q922P9), GLYR1_PONAB (Q5R7T2), GLYR1_RAT   (Q5RKH0), 
GLYR1_XENTR (Q562D5), GLYR2_ARATH (F4I907), LTND_CUPNH  (Q0KBC7), 
YFJR_BACSU  (O34969)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

3HIDH_MESAU (P86199)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
MSOX_STRAW  (Q827H4), MSOX_STRSB  (P40854)


				
	

	

		PDB
[Detailed view]		
		
			20 PDB
			


			2GF2; 2I9P; 3CKY; 3DOJ; 3OBB; 3Q3C; 4OM8; 5Y8G; 5Y8H; 5Y8I; 5Y8J; 5Y8K; 
			
				5Y8L; 5Y8M; 5Y8N; 5Y8O; 5Y8P; 6SM7; 6SMY; 6SMZ
			
			

			» more