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PROSITE entry PS00901


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00901
Entry name [info] CYS_SYNTHASE
Accession [info] PS00901
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00700

Name and characterization of the entry

Description [info] Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
Pattern [info] 
K-x-E-x(3,4)-[PAF]-[STAGC]-x-S-[IVAPM]-K-x-R-x-[STAG]-x(2)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 105 in 105 different sequences
Number of true positive hits 105 in 105 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.33 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 10
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 105 sequences 

CAS1_MALDO  (Q1KLZ2), CAS1_SOLTU  (Q76MX2), CAS2_MALDO  (Q1KLZ1), 

CAS2_SOLTU  (Q9FS29), CBS_APIME   (Q2V0C9), CBS_DICDI   (P46794), 
CBS_HUMAN   (P35520), CBS_MACFA   (Q58H57), CBS_MOUSE   (Q91WT9), 
CBS_RABIT   (Q9N0V7), CBS_RAT (P32232), CBS_YEAST   (P32582), 
CGL_ARATH   (F4K5T2), CYSC1_ARATH (Q9S757), CYSC_SPIOL  (Q43153), 
CYSD1_ARATH (Q9S6Z7), CYSD2_ARATH (Q9SXS7), CYSK1_ARATH (P47998), 
CYSK1_BRAJU (O23733), CYSK1_CAEEL (Q93244), CYSK1_ORYSJ (Q9XEA6), 
CYSK2_ARATH (Q9LJA0), CYSK2_BRAJU (O23735), CYSK2_CAEEL (O45679), 
CYSK2_ORYSJ (Q9XEA8), CYSK3_CAEEL (O01592), CYSK4_ARATH (O22682), 
CYSKL_NEUCR (Q7SHQ1), CYSKL_SCHPO (P87131), CYSKM_ARATH (Q43725), 
CYSKP_ARATH (P47999), CYSKP_CAPAN (P31300), CYSKP_SOLTU (O81155), 
CYSKP_SPIOL (P32260), CYSK_BACSU  (P37887), CYSK_BUCAI  (P57171), 
CYSK_BUCAP  (Q8KA48), CYSK_CITLA  (Q43317), CYSK_DICDI  (Q54CN7), 
CYSK_ECO57  (P0ABK6), CYSK_ECOLI  (P0ABK5), CYSK_EMENI  (P50867), 
CYSK_FLAS3  (Q59447), CYSK_HAEIN  (P45040), CYSK_MAIZE  (P80608), 
CYSK_MYCBO  (P0A535), CYSK_MYCLE  (O32978), CYSK_MYCTO  (P9WP54), 
CYSK_MYCTU  (P9WP55), CYSK_NEIMB  (Q7DDL5), CYSK_NEUCR  (Q7RYW6), 
CYSK_SALTI  (P0A1E4), CYSK_SALTY  (P0A1E3), CYSK_SCHPO  (O59701), 
CYSK_SOLTU  (O81154), CYSK_SPIOL  (Q00834), CYSK_STAAC  (Q5HIG2), 
CYSK_STAAM  (P63870), CYSK_STAAN  (P63871), CYSK_STAAR  (Q6GJF8), 
CYSK_STAAS  (Q6GBX5), CYSK_STAAW  (P63872), CYSK_STAEQ  (Q5HRP1), 
CYSK_STAES  (Q8CMT6), CYSK_STRP6  (Q5XAQ3), CYSK_SYNE7  (Q59966), 
CYSK_SYNY3  (P73410), CYSK_WHEAT  (P38076), CYSM_AQUAE  (O67507), 
CYSM_BACSU  (O34476), CYSM_CAMJE  (P71128), CYSM_ECOLI  (P16703), 
CYSM_HELPJ  (Q9ZMW6), CYSM_HELPY  (P56067), CYSM_MYCBO  (P63874), 
CYSM_MYCTO  (P9WP52), CYSM_MYCTU  (P9WP53), CYSM_PSEAE  (Q9I526), 
CYSM_PSESY  (P48028), CYSM_SALTY  (P29848), CYSO_AERPE  (Q9YBL2), 
DCSD_STRLA  (D2Z027), MCCA_BACSU  (O05393), MCY1_YEAST  (P53206), 
SBNA_CUPMC  (Q44004), SBNA_RALN1  (Q8XSQ0), SBNA_STAA0  (D1GUM7), 
SBNA_STAA1  (A7WX68), SBNA_STAA2  (A6TXQ1), SBNA_STAA3  (Q2FKE3), 
SBNA_STAA4  (D3ERF5), SBNA_STAA5  (D2N3G7), SBNA_STAA8  (Q2G1N3), 
SBNA_STAA9  (A5INY7), SBNA_STAAB  (Q2YUU0), SBNA_STAAC  (Q5HJQ3), 
SBNA_STAAD  (D0K799), SBNA_STAAE  (A6QDA0), SBNA_STAAM  (Q932K9), 
SBNA_STAAN  (Q99X99), SBNA_STAAR  (Q6GKI9), SBNA_STAAS  (Q6GD09), 
SBNA_STAAT  (A8YZ41), SBNA_STAAW  (Q7A1Z6), Y4XP_SINFN  (P55708)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

CAPA_CAPOD  (C7M8J5), CYSK2_MYCTU (Q79FV4), Y1077_MYCTO (P9WP50), 

Y1077_MYCTU (P9WP51)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

CYSK_CLOPA  (P81340), CYSK_POPEU  (P84538), CYSK_STAHA  (Q59918)


				
	

	

		PDB
[Detailed view]		
		
			92 PDB
			


			1FCJ; 1JBQ; 1M54; 1OAS; 1WKV; 1Y7L; 1Z7W; 2BHS; 2BHT; 2ISQ; 2JC3; 2Q3B; 
			
				2Q3C; 2Q3D; 2V03; 3DKI; 3DWG; 3DWI; 3FGP; 3IQG; 3IQH; 3IQI; 3VSA; 3X43; 
				3ZEI; 4AEC; 4COO; 4HO1; 4L0D; 4L27; 4L28; 4L3V; 4LI3; 4NU8; 4ORE; 4PCU; 
				4ZU1; 4ZU6; 5B36; 5B3A; 5D84; 5D85; 5D86; 5D87; 5DBE; 5DBH; 5I6D; 5I7A; 
				5I7H; 5I7O; 5I7R; 5IW8; 5IWC; 5J43; 5J5V; 5MMS; 5OHX; 5XCN; 5XCP; 5XCW; 
				6AHI; 6AIF; 6C2H; 6C2Q; 6C2Z; 6C4P; 6Z4N; 7C35; 7CM8; 7DJQ; 7EWO; 7N2T; 
				7QGT; 7YOD; 7YOE; 7YOF; 7YOG; 7YOH; 7YOI; 7YOK; 7YOL; 7YOM; 8GSK; 8S5H; 
				8S5I; 8S5J; 8S5K; 8S5L; 8S5M; 8STW; 8ZYC; 8ZYD
			
			

			» more