PROSITE entry PS00908

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PURL: https://purl.expasy.org/prosite/signature/PS00908

Direct ScanProsite submission

General information about the entry

Entry name [info]	MR_MLE_1
Accession [info]	PS00908
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00706

Name and characterization of the entry

Description [info]	Mandelate racemase / muconate lactonizing enzyme family signature 1.
Pattern [info]	[AT]-x-[SAGCN]-[SAGC]-[LIVM]-[DEQ]-x-A-[LA]-x-[DE]-[LIA]-x-[GA]-[KRQ]- x(4)-[PSA]-[LIV]-x(2)-L-[LIVMF]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2026_02 which contains 575'503 sequence entries.

Total number of hits	155 in 155 different sequences
Number of true positive hits	155 in 155 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	42
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	78.68 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

155 sequences

AEEP_CLOAB  (Q97MK4), AEEP_ECOLI  (P51981), CATB1_ACILW (O33946),

CATB2_ACILW (O33949), CATB_ACIAD  (Q43931), CATB_PSEPU  (P08310), 
CATB_RHOOP  (P95608), CBNB_CUPNE  (P83763), CLCB_PSEPU  (P11452), 
DGD_PANAM   (D4GJ14), DGD_SALEP   (B5R541), DGD_SALV4   (B5QBD4), 
DGOD1_ECOSM (B1LPS5), DGOD2_ECOSM (B1LL17), DGOD_CROS8  (A7MN07), 
DGOD_ECO24  (A7ZTP7), DGOD_ECO45  (B7MGB3), DGOD_ECO55  (B7L836), 
DGOD_ECO7I  (B7NQZ2), DGOD_ECO81  (B7N1Z6), DGOD_ECO8A  (B7M4I1), 
DGOD_ECOBW  (C4ZYW9), DGOD_ECODH  (B1X9C1), DGOD_ECOHS  (A8A6F2), 
DGOD_ECOK1  (A1AHM7), DGOD_ECOL5  (Q0TB15), DGOD_ECOLC  (B1IYQ2), 
DGOD_ECOLI  (Q6BF17), DGOD_ECOLU  (B7NF09), DGOD_ECOSE  (B6I3S5), 
DGOD_ECOUT  (Q1R4P4), DGOD_ENT38  (A4W4R9), DGOD_ESCF3  (B7LK34), 
DGOD_KLEP7  (A6TFZ4), DGOD_KLEV3  (B5XW18), DGOD_PECAS  (Q6CYT9), 
DGOD_RALN1  (Q8XVS8), DGOD_RALPJ  (B2UCA8), DGOD_SALCH  (Q57I11), 
DGOD_SALDC  (B5FN00), DGOD_SALEP  (B5QUN9), DGOD_SALG2  (B5RFZ8), 
DGOD_SALHS  (B4TA81), DGOD_SALNS  (B4SY97), DGOD_SALPB  (A9MWL9), 
DGOD_SALPK  (B5BIK9), DGOD_SALTY  (Q8ZKZ1), DGOD_SERP5  (A8G7R4), 
DGOD_VARPS  (C5CZC3), DGOD_VEREI  (A1WPC7), DGOD_XANC3  (Q8PLN0), 
DGOD_XANC8  (Q4UTT5), DGOD_XANCB  (B0RTW1), DGOD_XANCP  (Q8P9V1), 
DGOD_XANE5  (Q3BUN6), DGOD_XANOM  (Q2P1Q3), DGOD_XANOP  (B2SV55), 
DMGD_CHRI1  (Q1QT89), DMGD_HALED  (E1V4Y0), DMGD_MUSP7  (C6CBG9), 
GAD_THETE   (Q704D2), GCI_AGRFC   (A9CEQ8), GUDX_ECOLI  (Q46915), 
HYEP_ROSLO  (F7ZLS5), IMAND_CATAD (C7PW26), IMAND_CLOB8 (A6M2W4), 
IMAND_ENT38 (A4W7D6), IMAND_ENTBW (A8RQK7), IMAND_ENTCS (C9CN91), 
IMAND_OCEGH (Q2CIN0), IMAND_PAESJ (C6CVY9), IMAND_PECAS (Q6DAR4), 
IMAND_PECCP (C6DI84), IMAND_PECPW (D0KC90), IMAND_PSECP (B8HCK2), 
IMAND_STRSH (B5GCP6), IMAND_VIBBS (A5KUH4), IMAND_VIBH1 (D0X4R4), 
IMND1_ENTGE (C8ZZN2), IMND1_VIBCR (C9NUM5), IMND2_ENTGE (C9A1P5), 
IMND2_VIBCY (A6AMN2), LYXD_CUPNH  (Q0K4Q6), MAND1_CAUSK (B0T0B1), 
MAND1_CAUVC (Q9A4L8), MAND2_CAUSK (B0T4L2), MAND2_CAUVC (Q9AAR4), 
MAND_CELJU  (B3PDB1), MAND_ECOL6  (Q8FHC7), MAND_ECOMS  (D8ADB5), 
MAND_ENT38  (A4WA78), MAND_ESCAT  (B1ELW6), MAND_MARMS  (A6VRA1), 
MAND_NOVAD  (A4XF23), MAND_PECCP  (C6D9S0), MAND_RHIWR  (A5V6Z0), 
MAND_SALG2  (B5RAG0), MAND_SPHSS  (Q1NAJ2), MAND_STRS3  (D9UNB2), 
MAND_XANOB  (G7TAD9), MANR_PSEPU  (P11444), RHMD_AZOC5  (A8I5F1), 
RHMD_BURA4  (B1YMY4), RHMD_BURCH  (A0KDV2), RHMD_BURCM  (Q0BA70), 
RHMD_BURO0  (B1KAV6), RHMD_BURO1  (Q1BGJ0), RHMD_CALMQ  (A8MA91), 
RHMD_DELAS  (A9BQY2), RHMD_ECO27  (B7UFQ9), RHMD_ECO45  (B7MG14), 
RHMD_ECO57  (Q8XE07), RHMD_ECO81  (B7MXS8), RHMD_ECOBW  (C4ZU89), 
RHMD_ECODH  (B1X8W0), RHMD_ECOHS  (A8A2B3), RHMD_ECOK1  (A1AD99), 
RHMD_ECOL5  (Q0TFJ5), RHMD_ECOL6  (Q8FFM8), RHMD_ECOLC  (B1IXU0), 
RHMD_ECOLI  (P77215), RHMD_ECOSM  (B1LLK1), RHMD_ECOUT  (Q1R9G8), 
RHMD_KLEP7  (A6TBU8), RHMD_KLEV3  (B5XNY1), RHMD_PARP8  (B2JLI8), 
RHMD_PARPJ  (B2TFM7), RHMD_PARXL  (Q13LW5), RHMD_POLSJ  (Q12DF1), 
RHMD_SACEN  (A4FLW9), RHMD_SALA4  (B5EZH0), RHMD_SALCH  (Q57M62), 
RHMD_SALDC  (B5FNT1), RHMD_SALEP  (B5R264), RHMD_SALG2  (B5RCB6), 
RHMD_SALHS  (B4TBF8), RHMD_SALNS  (B4SYW3), RHMD_SALPA  (Q5PIM9), 
RHMD_SALPB  (A9N5C2), RHMD_SALPC  (C0Q077), RHMD_SALPK  (B5BCQ4), 
RHMD_SALSV  (B4TPH4), RHMD_SALTI  (Q8Z548), RHMD_SALTY  (Q8ZNF9), 
RHMD_SHIBS  (Q31Z80), RHMD_SHISS  (Q3YZV9), RHMD_SPHSS  (Q1NEI8), 
RHMD_TOLAT  (C4LDK0), RHMD_VEREI  (A1WFL2), RSPA_ECOLI  (P38104), 
TCBD_PSESQ  (P27099), TFDD1_CUPPJ (P05404), TFDD2_CUPPJ (P42428), 
TFDD_DELAC  (Q9RNZ9), YIN2_STRAM  (P32426)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

42 sequences

AAEP_CYTH3  (Q11T61), ACI_STRCO   (Q9RKF7), ACI_VIBSJ   (H2IFX0),

AEEP_BACSU  (O34508), AEEP_BACTN  (Q8A861), AEEP_FRATN  (A0Q5S7), 
AEEP_THEMA  (Q9WXM1), AREP_HERA2  (A9B055), AXEP_FLAJ1  (A5FHW9), 
AXEP_MARSH  (A4AQI7), AXEP_PEDPL  (B9XEK4), AXEP_POPTR  (B9I2J6), 
C3HPD_ANCN5 (D7A0Y2), C3HPD_ROSAI (A0NXQ8), DGCA_PSEAS  (P0DXZ2), 
DGD_STRBB   (D7BPX0), ENOF1_BOVIN (Q2KIA9), ENOF1_HUMAN (Q7L5Y1), 
ENOF1_PONAB (Q5RAT4), ENOF1_XENLA (Q6INX4), GAD_SACS2   (Q97U27), 
GALRD_OCEIH (Q8EMJ9), HPBD_PARDP  (A1B198), HPBD_SALBH  (Q0FPQ4), 
HYEP_CITBB  (B5EFW2), HYEP_ENTFA  (Q834W6), HYEP_FLABM  (C0BK17), 
KRDE_DESAH  (C0QM06), KRDE_METCA  (Q607C7), LGD1_TRIRF  (Q0QWS4), 
LYXD_DINSH  (A8LS88), LYXD_PSEAE  (Q9I1Q2), LYXD_ROSAI  (A0NP48), 
LYXD_VEREI  (A1WLE4), NSAR_BACCR  (Q81IL5), PHYLO_ARATH (Q15KI9), 
TAGAD_SALTY (Q8ZL58), TARD_BRADU  (Q89FH0), XEEP_FRAP2  (B0TZW0), 
XEEP_SULDN  (Q30PM2), Y4701_DICDI (P0CC06), YITF_BACSU  (O06741)

» more

PDB
[Detailed view]

73 PDB

pdb_00001dtn; pdb_00001jpd; pdb_00001mdl; pdb_00001mdr; pdb_00001mns; pdb_00001mra; pdb_00001muc; pdb_00001nu5; pdb_00002chr; pdb_00002gsh; pdb_00002i5q; pdb_00002mnr; pdb_00002muc; pdb_00002p3z; pdb_00002qjj; pdb_00002qjm; pdb_00002qjn; pdb_00003box; pdb_00003bsm; pdb_00003cxo; pdb_00003d46; pdb_00003d47; pdb_00003dfh; pdb_00003gy1; pdb_00003muc; pdb_00003ow1; pdb_00003p93; pdb_00003pk7; pdb_00003qke; pdb_00003r25; pdb_00003rgt; pdb_00003rr1; pdb_00003rra; pdb_00003s47; pdb_00003sbf; pdb_00003t6c; pdb_00003thu; pdb_00003tji; pdb_00003tw9; pdb_00003twa; pdb_00003twb; pdb_00003uxk; pdb_00003uxl; pdb_00003v3w; pdb_00003v4b; pdb_00003vcn; pdb_00004e4f; pdb_00004f4r; pdb_00004fi4; pdb_00004fp1; pdb_00004ggb; pdb_00004ggh; pdb_00004gir; pdb_00004gis; pdb_00004gme; pdb_00004gyp; pdb_00004hnc; pdb_00004hnl; pdb_00004hpn; pdb_00004ihc; pdb_00004il0; pdb_00004il2; pdb_00004k1w; pdb_00004k2s; pdb_00004k8g; pdb_00004kpl; pdb_00004kt2; pdb_00004kws; pdb_00004m6u; pdb_00004x2p; pdb_00006vim; pdb_00007mqx; pdb_00009p1b
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