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PROSITE entry PS00913


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00913
Entry name [info] ADH_IRON_1
Accession [info] PS00913
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-JUL-1998 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00059

Name and characterization of the entry

Description [info] Iron-containing alcohol dehydrogenases signature 1.
Pattern [info] 
[STALIV]-[LIVF]-x-[DE]-x(6,7)-P-x(4)-[ALIV]-x-[GST]-x(2)-D-[TAIVM]-
[LIVMF]-x(4)-E.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 51 in 51 different sequences
Number of true positive hits 43 in 43 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 31
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 84.31 %
Recall (true positives / (true positives + false negatives)) 58.11 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 43 sequences 

4HBDH_CUPNE (Q59104), ADH1_CLOSA  (P13604), ADH1_GEOTN  (A4IP64), 

ADH2_ECOLI  (P37686), ADH2_ENTH1  (Q24803), ADH2_GEOTN  (A4ISB9), 
ADH2_ZYMMA  (F8DVL8), ADH2_ZYMMO  (P0DJA2), ADH4_SCHPO  (Q09669), 
ADH4_YEAS7  (A6ZTT5), ADH4_YEAST  (P10127), ADHA_CLOAB  (Q04944), 
ADHB_CLOAB  (Q04945), ADHE_CLOAB  (P33744), ADHE_ECO57  (P0A9Q8), 
ADHE_ECOLI  (P0A9Q7), ADHE_STRP2  (A0A0H2ZM56), ADHE_STRPN  (A0A0H2URT2), 
DHAT_CITFR  (P45513), DHAT_KLEPN  (Q59477), EUTG_ECOLI  (P76553), 
EUTG_SALTY  (P41795), FUCO_ECO57  (P0A9S2), FUCO_ECOLI  (P0A9S1), 
GBSB_BACSU  (P71017), GLD1_SCHPO  (O13702), GLDA_CITFR  (P45511), 
GLDA_ECOL6  (P0A9S6), GLDA_ECOLI  (P0A9S5), GLDA_GEOSE  (P32816), 
GLDA_PSEPU  (P50173), GLDA_THEMA  (Q9WYQ4), HCXA_ECOLI  (P45579), 
HOT_CAEBR   (A8WTJ7), HOT_CAEEL   (Q9U2M4), MEDH_BACMT  (P31005), 
PDUQ_CITFR  (B1VB76), PDUQ_SALTY  (Q9XDN0), SARD_BILW3  (E5Y946), 
SQWF_CLOS9  (J1H1J3), YQHD_ECOLI  (Q46856), YUGJ_BACSU  (O05239), 
YUGK_BACSU  (O05240)
» more

UniProtKB/Swiss-Prot
False negative sequences		 31 sequences 

4HBDH_CLOK5 (P38945), ADH3_ENTH1  (Q24857), ADHA_THEET  (Q9F282), 

ADH_THEBA   (A0A0S1X9S7), CLCE_PSEAI  (O87612), CLCE_PSEKB  (O30847), 
GLYAR_HALSA (Q9HHR2), GRAC_RHIS5  (A1IIX4), HOT_AEDAE   (Q17EN4), 
HOT_ANOGA   (Q7Q547), HOT_BOVIN   (A6QP15), HOT_DICDI   (Q54GJ7), 
HOT_DROME   (Q9W265), HOT_DROPS   (Q28XT3), HOT_HUMAN   (Q8IWW8), 
HOT_MOUSE   (Q8R0N6), HOT_PONAB   (Q5RF11), HOT_RAT (Q4QQW3), 
HOT_XENLA   (Q08B39), HOT_XENTR   (Q6P371), KDNB_SHEON  (Q8EEB0), 
LINF_SPHIU  (Q5W9E3), MACA1_RHOOP (O84992), MNO_RHOER   (Q53062), 
PHPC_STRVT  (D9XF45), TCBF_PSESQ  (P27101), TFDF1_CUPPJ (P27137), 
TFDF2_CUPPJ (P94135), TFDF_DELAC  (Q93T12), TFTE_BURCE  (Q45072), 
Y1167_SYNY3 (P74246)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

MACA2_RHOOP (P56870)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			8 sequences
			


			
CARB_ARATH  (Q42601), CARB_ORYSJ  (B9EXM2), DNLJ_RHIE6  (B3PTU7), 

			
DNLJ_RHIEC  (Q2K6D3), DNLJ_RHIJ3  (Q1ME47), DNLJ_RHILW  (B5ZWH9), 
DNLJ_RHIR8  (B9JH39), SETD2_HUMAN (Q9BYW2)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			34 PDB
			


			1JPU; 1JQ5; 1JQA; 1KQ3; 1OJ7; 1RRM; 1TA9; 2BI4; 2BL4; 3BFJ; 3OWO; 3OX4; 
			
				4QGS; 5BR4; 5ZXL; 6AHC; 6SCG; 6SCI; 6TQH; 6TQM; 7BVP; 7QLG; 7QLQ; 7QLS; 
				7QNF; 7QNH; 7QNI; 7QNJ; 7R0P; 7R3D; 7R5T; 8GOA; 8GOB; 8X6M
			
			

			» more