PROSITE logo

PROSITE entry PS00915


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00915

Direct ScanProsite submission
General information about the entry

Entry name [info] PI3_4_KINASE_1
Accession [info] PS00915
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00710

Name and characterization of the entry

Description [info] Phosphatidylinositol 3- and 4-kinases signature 1.
Pattern [info] 
[LIVMFAC]-K-x(1,3)-[DEA]-[DE]-[LIVMCP]-R-Q-[DE]-x(4)-Q.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 103 in 103 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 33
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 75.74 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 103 sequences 

AGE1_CAEBR  (P0C5E7), AGE1_CAEEL  (Q94125), ATM_ARATH   (Q9M3G7), 

ATM_ASPFU   (Q4WVM7), ATM_ASPOR   (Q2U639), ATM_CANGA   (Q6FRZ9), 
ATM_DEBHA   (Q6BV76), ATM_DROME   (Q5EAK6), ATM_EMENI   (Q5BHE2), 
ATM_EREGS   (Q751J3), ATM_GIBZE   (Q4IB89), ATM_HUMAN   (Q13315), 
ATM_KLULA   (Q6CP76), ATM_MOUSE   (Q62388), ATM_NEUCR   (Q7RZT9), 
ATM_PIG (Q6PQD5), ATM_SCHPO   (O74630), ATM_YARLI   (Q6CAD2), 
ATM_YEAST   (P38110), ATR_CANGA   (Q6FX42), ATR_EREGS   (Q75DB8), 
ATR_KLULA   (Q6CT34), ATR_YEAST   (P38111), MTOR_HUMAN  (P42345), 
MTOR_MOUSE  (Q9JLN9), MTOR_RAT(P42346), P3C2A_HUMAN (O00443), 
P3C2A_MOUSE (Q61194), P3C2A_PONAB (Q5RAY1), P3C2B_HUMAN (O00750), 
P3C2G_HUMAN (O75747), P3C2G_MOUSE (O70167), P3C2G_RAT   (O70173), 
P4KA1_ARATH (Q9SXA1), P4KA2_ARATH (Q9C680), P4KB1_ARATH (Q9FMJ0), 
P4KB2_ARATH (Q0WPX9), PI3K1_DICDI (P54673), PI3K1_SOYBN (P42347), 
PI3K2_DICDI (P54674), PI3K2_SOYBN (P42348), PI3K3_DICDI (P54675), 
PI3K4_DICDI (P54676), PI3K_ARATH  (P42339), PI4KA_BOVIN (O02811), 
PI4KA_HUMAN (P42356), PI4KA_MOUSE (E9Q3L2), PI4KA_RAT   (O08662), 
PI4KB_BOVIN (O02810), PI4KB_CALJA (B0KWC1), PI4KB_DANRE (Q49GP3), 
PI4KB_HUMAN (Q9UBF8), PI4KB_MOUSE (Q8BKC8), PI4KB_OTOGA (B4UT09), 
PI4KB_PAPAN (A9X1A0), PI4KB_PLEMO (B1MTG7), PI4KB_RAT   (O08561), 
PI4KB_RHIFE (B2KI64), PI4KB_SORAR (B3EX61), PI4KB_XENLA (Q6GN16), 
PI4KB_XENTR (A4IID4), PI4K_DICDI  (P54677), PIK1_SCHPO  (Q10366), 
PIK1_YEAST  (P39104), PK3C3_CAEEL (Q9TXI7), PK3C3_HUMAN (Q8NEB9), 
PK3C3_MOUSE (Q6PF93), PK3C3_PIG   (Q5D891), PK3C3_RAT   (O88763), 
PK3C3_XENLA (Q6AZN6), PK3CA_BOVIN (P32871), PK3CA_HUMAN (P42336), 
PK3CA_MOUSE (P42337), PK3CA_RAT   (A0A0G2K344), PK3CB_HUMAN (P42338), 
PK3CB_MOUSE (Q8BTI9), PK3CB_RAT   (Q9Z1L0), PK3CD_HUMAN (O00329), 
PK3CD_MOUSE (O35904), PK3CG_HUMAN (P48736), PK3CG_MOUSE (Q9JHG7), 
PK3CG_PIG   (O02697), PRKDC_CANLF (Q8WN22), PRKDC_CHICK (Q8QGX4), 
PRKDC_HUMAN (P78527), PRKDC_MOUSE (P97313), PRKDC_XENLA (Q9DEI1), 
STT4_ENCCU  (Q8SQY7), STT4_SCHPO  (Q9USR3), STT4_YEAST  (P37297), 
TOR1_SCHPO  (O14356), TOR1_YEAST  (P35169), TOR2_SCHPO  (Q9Y7K2), 
TOR2_YEAST  (P32600), TOR_ARATH   (Q9FR53), TOR_CAEEL   (Q95Q95), 
TOR_DICDI   (Q86C65), TOR_DROME   (Q9VK45), TOR_ORYSJ   (Q0DJS1), 
VPS34_CANAL (A0A1D8PDV7), VPS34_CANAX (Q92213), VPS34_SCHPO (P50520), 
VPS34_YEAST (P22543)
» more

UniProtKB/Swiss-Prot
False negative sequences		 33 sequences 

LSB6_SCHPO  (Q9UT42), LSB6_YEAST  (P42951), P4K2A_DANRE (Q6PE18), 

P4K2A_HUMAN (Q9BTU6), P4K2A_MOUSE (Q2TBE6), P4K2A_RAT   (Q99M64), 
P4K2A_XENLA (Q08B31), P4K2A_XENTR (Q505I0), P4K2B_CHICK (Q5ZIK0), 
P4K2B_DANRE (Q49GP5), P4K2B_HUMAN (Q8TCG2), P4K2B_MOUSE (Q8CBQ5), 
P4K2B_RAT   (Q5XIL2), P4K2B_XENLA (Q6DCQ8), P4K2B_XENTR (Q28G26), 
P4KG1_ARATH (O22199), P4KG2_ARATH (Q9SGW8), P4KG3_ARATH (Q9FNF8), 
P4KG4_ARATH (Q9ZPY9), P4KG4_ORYSJ (Q6K881), P4KG5_ARATH (Q9C671), 
P4KG6_ARATH (Q8W4R8), P4KG7_ARATH (Q9SI52), P4KG8_ARATH (Q0WMZ6), 
PI4P2_HUMAN (A4QPH2), PIK1A_CANAL (Q9UW24), PIK1_CANAL  (Q9UW20), 
PIKI1_CAEEL (G5EDY0), TRA1_SCHPO  (Q9HFE8), TRA2_SCHPO  (Q10064), 
VPS34_CANGA (Q6FSR7), VPS34_ENCCU (Q8SR56), YL615_MIMIV (Q5UR69)
» more

PDB
[Detailed view]		 437 PDB

pdb_00001e7u; pdb_00001e7v; pdb_00001e8w; pdb_00001e8x; pdb_00001e8y; pdb_00001e8z; pdb_00001e90; pdb_00001he8; pdb_00002a4z; pdb_00002a5u; pdb_00002chw; pdb_00002chx; pdb_00002chz; pdb_00002rd0; pdb_00002v4l; pdb_00002wxf; pdb_00002wxg; pdb_00002wxh; pdb_00002wxi; pdb_00002wxj; pdb_00002wxk; pdb_00002wxl; pdb_00002wxm; pdb_00002wxn; pdb_00002wxo; pdb_00002wxp; pdb_00002wxq; pdb_00002wxr; pdb_00002x38; pdb_00002y3a; pdb_00003apc; pdb_00003apd; pdb_00003apf; pdb_00003csf; pdb_00003cst; pdb_00003dbs; pdb_00003dpd; pdb_00003ene; pdb_00003hhm; pdb_00003hiz; pdb_00003ibe; pdb_00003ihy; pdb_00003jbz; pdb_00003l08; pdb_00003l13; pdb_00003l16; pdb_00003l17; pdb_00003l54; pdb_00003lj3; pdb_00003ls8; pdb_00003mjw; pdb_00003ml8; pdb_00003ml9; pdb_00003nzs; pdb_00003nzu; pdb_00003oaw; pdb_00003p2b; pdb_00003pre; pdb_00003prz; pdb_00003ps6; pdb_00003qaq; pdb_00003qar; pdb_00003qjz; pdb_00003qk0; pdb_00003r7q; pdb_00003r7r; pdb_00003s2a; pdb_00003sd5; pdb_00003t8m; pdb_00003tjp; pdb_00003tl5; pdb_00003zim; pdb_00003zvv; pdb_00003zw3; pdb_00004a55; pdb_00004ajw; pdb_00004anu; pdb_00004anv; pdb_00004anw; pdb_00004anx; pdb_00004aof; pdb_00004bfr; pdb_00004d0l; pdb_00004d0m; pdb_00004dk5; pdb_00004ezj; pdb_00004ezk; pdb_00004ezl; pdb_00004f1s; pdb_00004fa6; pdb_00004fad; pdb_00004fhj; pdb_00004fhk; pdb_00004fjy; pdb_00004fjz; pdb_00004flh; pdb_00004ful; pdb_00004g11; pdb_00004gb9; pdb_00004hle; pdb_00004hvb; pdb_00004j6i; pdb_00004jps; pdb_00004jsn; pdb_00004jsp; pdb_00004jsv; pdb_00004jsx; pdb_00004jt5; pdb_00004jt6; pdb_00004kz0; pdb_00004kzc; pdb_00004l1b; pdb_00004l23; pdb_00004l2y; pdb_00004ovu; pdb_00004ovv; pdb_00004oys; pdb_00004ph4; pdb_00004ps3; pdb_00004ps7; pdb_00004ps8; pdb_00004tuu; pdb_00004tv3; pdb_00004urk; pdb_00004uwf; pdb_00004uwg; pdb_00004uwh; pdb_00004uwk; pdb_00004uwl; pdb_00004v0i; pdb_00004wae; pdb_00004waf; pdb_00004wag; pdb_00004wwn; pdb_00004wwo; pdb_00004wwp; pdb_00004xe0; pdb_00004xx5; pdb_00004xz4; pdb_00004ykn; pdb_00004zop; pdb_00005ae8; pdb_00005ae9; pdb_00005anl; pdb_00005c46; pdb_00005c4g; pdb_00005dfz; pdb_00005dxh; pdb_00005dxt; pdb_00005dxu; pdb_00005eds; pdb_00005enn; pdb_00005euq; pdb_00005fbl; pdb_00005fbq; pdb_00005fbr; pdb_00005fbv; pdb_00005fbw; pdb_00005fi4; pdb_00005flc; pdb_00005g2n; pdb_00005g55; pdb_00005h64; pdb_00005i4u; pdb_00005i6u; pdb_00005is5; pdb_00005itd; pdb_00005jha; pdb_00005jhb; pdb_00005kae; pdb_00005kc2; pdb_00005l72; pdb_00005luq; pdb_00005m6u; pdb_00005ncy; pdb_00005ncz; pdb_00005ngb; pdb_00005np0; pdb_00005np1; pdb_00005o83; pdb_00005oq4; pdb_00005sw8; pdb_00005swg; pdb_00005swo; pdb_00005swp; pdb_00005swr; pdb_00005swt; pdb_00005sx8; pdb_00005sx9; pdb_00005sxa; pdb_00005sxb; pdb_00005sxc; pdb_00005sxd; pdb_00005sxe; pdb_00005sxf; pdb_00005sxi; pdb_00005sxj; pdb_00005sxk; pdb_00005t23; pdb_00005t27; pdb_00005t28; pdb_00005t2b; pdb_00005t2d; pdb_00005t2g; pdb_00005t2i; pdb_00005t2l; pdb_00005t2m; pdb_00005t7f; pdb_00005t8f; pdb_00005t8i; pdb_00005ubr; pdb_00005ubt; pdb_00005uk8; pdb_00005ukj; pdb_00005ul1; pdb_00005vlr; pdb_00005w1r; pdb_00005wbu; pdb_00005wby; pdb_00005x6o; pdb_00005xgh; pdb_00005xgi; pdb_00005xgj; pdb_00005y3r; pdb_00005zcs; pdb_00006aud; pdb_00006bcu; pdb_00006bcx; pdb_00006bq1; pdb_00006c1s; pdb_00006dgt; pdb_00006emk; pdb_00006eyz; pdb_00006ez6; pdb_00006fh5; pdb_00006g6w; pdb_00006gl3; pdb_00006gq7; pdb_00006gvf; pdb_00006gvg; pdb_00006gvh; pdb_00006gvi; pdb_00006gy0; pdb_00006hi9; pdb_00006i3u; pdb_00006jxa; pdb_00006jxc; pdb_00006k9k; pdb_00006k9l; pdb_00006mul; pdb_00006mum; pdb_00006nct; pdb_00006oac; pdb_00006oco; pdb_00006ocu; pdb_00006pyr; pdb_00006pys; pdb_00006pyu; pdb_00006s8f; pdb_00006sb0; pdb_00006sb2; pdb_00006t3b; pdb_00006t3c; pdb_00006xrl; pdb_00006xrm; pdb_00006xrn; pdb_00006ykg; pdb_00006z2w; pdb_00006z2x; pdb_00006z3a; pdb_00006zfp; pdb_00006zh2; pdb_00006zh4; pdb_00006zh6; pdb_00006zh8; pdb_00006zha; pdb_00006zhe; pdb_00006zwm; pdb_00006zwo; pdb_00007bi2; pdb_00007bi4; pdb_00007bi6; pdb_00007bi9; pdb_00007bl1; pdb_00007jis; pdb_00007jiu; pdb_00007jwe; pdb_00007jwz; pdb_00007jx0; pdb_00007k0y; pdb_00007k10; pdb_00007k11; pdb_00007k19; pdb_00007k1b; pdb_00007k1j; pdb_00007k1k; pdb_00007k1n; pdb_00007k6m; pdb_00007k6n; pdb_00007k6o; pdb_00007k71; pdb_00007kke; pdb_00007lm2; pdb_00007lq1; pdb_00007lt3; pdb_00007mez; pdb_00007mlk; pdb_00007myn; pdb_00007myo; pdb_00007nfc; pdb_00007nfe; pdb_00007ni4; pdb_00007ni5; pdb_00007ni6; pdb_00007otm; pdb_00007otp; pdb_00007otv; pdb_00007otw; pdb_00007oty; pdb_00007owg; pdb_00007pe7; pdb_00007pe8; pdb_00007pe9; pdb_00007pea; pdb_00007peb; pdb_00007pec; pdb_00007pg5; pdb_00007pg6; pdb_00007pqh; pdb_00007r9v; pdb_00007r9y; pdb_00007rsj; pdb_00007rsp; pdb_00007rsv; pdb_00007sgl; pdb_00007sic; pdb_00007sid; pdb_00007su3; pdb_00007sud; pdb_00007tyr; pdb_00007tz7; pdb_00007tzo; pdb_00007uxc; pdb_00007uxh; pdb_00007wzr; pdb_00007wzw; pdb_00007z61; pdb_00007z74; pdb_00007z75; pdb_00007z87; pdb_00007z88; pdb_00008a9i; pdb_00008aj8; pdb_00008am0; pdb_00008bcy; pdb_00008bfu; pdb_00008bh3; pdb_00008bhv; pdb_00008bhy; pdb_00008bot; pdb_00008dcp; pdb_00008dcx; pdb_00008dd4; pdb_00008dd8; pdb_00008dp0; pdb_00008era; pdb_00008exl; pdb_00008exo; pdb_00008exu; pdb_00008exv; pdb_00008ez9; pdb_00008eza; pdb_00008ezb; pdb_00008gua; pdb_00008gub; pdb_00008gud; pdb_00008ilr; pdb_00008ils; pdb_00008ilv; pdb_00008ow2; pdb_00008oxm; pdb_00008oxo; pdb_00008oxp; pdb_00008oxq; pdb_00008q6f; pdb_00008q6g; pdb_00008q6h; pdb_00008rch; pdb_00008rck; pdb_00008rcn; pdb_00008rd4; pdb_00008rxr; pdb_00008s3r; pdb_00008sbc; pdb_00008sbj; pdb_00008sc8; pdb_00008so9; pdb_00008soa; pdb_00008sob; pdb_00008soc; pdb_00008sod; pdb_00008soe; pdb_00008sor; pdb_00008tdu; pdb_00008tgd; pdb_00008ts7; pdb_00008ts8; pdb_00008ts9; pdb_00008tsa; pdb_00008tsb; pdb_00008tsc; pdb_00008tsd; pdb_00008tu6; pdb_00008twy; pdb_00008v8h; pdb_00008v8i; pdb_00008v8j; pdb_00008v8u; pdb_00008v8v; pdb_00008vof; pdb_00008w9a; pdb_00008w9b; pdb_00009b4s; pdb_00009b4t; pdb_00009b9g; pdb_00009bax; pdb_00009c15; pdb_00009c82; pdb_00009e4v; pdb_00009f44; pdb_00009f45; pdb_00009gcf; pdb_00009gdi; pdb_00009gg9; pdb_00009mhf; pdb_00009mhg; pdb_00009mhh
» more