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PROSITE entry PS00919


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00919
Entry name [info] DNASE_I_1
Accession [info] PS00919
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00711

Name and characterization of the entry

Description [info] Deoxyribonuclease I signature 1.
Pattern [info] 
[LIVM](2)-[AP]-[LQ]-H-[STA]-[STAE]-P-x(5)-E-[LIVM]-[DN]-x-L-x-[DE]-V.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 22 in 22 different sequences
Number of true positive hits 22 in 22 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 22 sequences 

DNAS1_BOVIN (P00639), DNAS1_CANLF (Q767J3), DNAS1_CHICK (Q9YGI5), 

DNAS1_HORSE (Q4AEE3), DNAS1_HUMAN (P24855), DNAS1_MOUSE (P49183), 
DNAS1_OREMO (O42446), DNAS1_PIG   (P11936), DNAS1_RABIT (O18998), 
DNAS1_RAT   (P21704), DNAS1_SHEEP (P11937), DNSL1_BOVIN (Q2QDE9), 
DNSL1_CHLAE (Q2QDF1), DNSL1_CRIGR (Q2QDE6), DNSL1_HUMAN (P49184), 
DNSL1_MOUSE (Q9D7J6), DNSL1_RAT   (Q2QDE7), DNSL2_HUMAN (Q92874), 
DNSL2_MOUSE (Q9D1G0), DNSL3_HUMAN (Q13609), DNSL3_MOUSE (O55070), 
DNSL3_RAT   (O89107)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

DNAS1_THISK (D3SGB1), DNSL1_PIG   (Q2QDF0)


				
	

	

		PDB
[Detailed view]		
		
			17 PDB
			


			1ATN; 1DNK; 2A3Z; 2A40; 2A41; 2A42; 2D1K; 2DNJ; 3CJC; 3DNI; 3W3D; 4AWN; 
			
				7KIU; 7NXV; 7NZM; 9FJU; 9FJY
			
			

			» more