PROSITE entry PS00921
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PURL: https://purl.expasy.org/prosite/signature/PS00921
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General information about the entry
| Entry name [info] | NITRIL_CHT_2 | 
| Accession [info] | PS00921 | 
| Entry type [info] | PATTERN | 
| Date [info] | 01-OCT-1993 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE. | 
| PROSITE Doc. [info] | PDOC00712 | 
| Associated ProRule [info] | PRU10105 | 
Name and characterization of the entry
| Description [info] | Nitrilases / cyanide hydratase active site signature. | 
| Pattern [info] | G-[GAQ]-x(2)-C-[WA]-E-[NH]-x(2)-[PST]-[LIVMFYS]-x-[KR]. | 
Numerical results [info]
| Total number of hits | 38 in 38 different sequences | 
| Number of true positive hits | 38 in 38 different sequences | 
| Number of 'unknown' hits | 0 | 
| Number of false positive hits | 0 | 
| Number of false negative sequences | 6 | 
| Number of 'partial' sequences | 1 | 
| Precision (true positives / (true positives + false positives)) | 100.00 % | 
| Recall (true positives / (true positives + false negatives)) | 86.36 % | 
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) | 
| Maximum number of repetitions [info] | 1 | 
| Site [info] | active_site at position 4 | 
| Version [info] | 1 | 
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences | 38 sequences CHT_ALTBR (Q7Z8M6), CHT_BOTF4 (G2XQT1), CHT_FUSSL (Q96UG7), CHT_GIBBA (P32963), CHT_GIBZE (I1RP53), CHT_LEPMC (Q9P8V3), CHT_MICSH (P32964), CHT_NEUCR (Q7RVT0), CHT_PYRTT (E3RV84), CHT_STEHR (P9WEU5), NIT1_ASPKW (G7XTA8), NIT1_ASPNC (A2R6M7), NIT1_YEAST (P40447), NIT2_ASPKW (G7X8S6), NIT2_ASPNC (A2RA31), NIT2_PENRW (B6HVR6), NITR1_BRADU (Q89GE3), NITR2_BRADU (Q89PT3), NITR_PARP8 (B2JQY2), NITR_PSEU2 (Q500U1), NIT_ASPOR (Q2U4D6), NIT_AURST (A0A0P1DJE3), NIT_MACPH (K2QXC4), NIT_SINF1 (G9AIU0), NIT_TALMQ (B6Q5I3), NRL1_ARATH (P32961), NRL1_RHORH (Q02068), NRL2_ARATH (P32962), NRL2_RHORH (Q03217), NRL3_ARATH (P46010), NRL4A_LUPAN (Q5QGZ8), NRL4A_TOBAC (Q42965), NRL4B_LUPAN (Q3LRV4), NRL4B_TOBAC (Q42966), NRL4_ARATH (P46011), NRL4_ORYSJ (Q6H849), NRLA_ALCFA (P20960), NRLB_KLEPO (P10045)» more 
 | 
| UniProtKB/Swiss-Prot False negative sequences | 6 sequences CHT_ASPNG (A9QXE0), CHT_EMENI (C8V9R7), CHT_PENRW (B6HCY4), NITR2_UNKP (Q6RWK4), NITR3_UNKP (Q6RWG0), NRL_BACSX (P82605)» more | 
| UniProtKB/Swiss-Prot 'Partial' sequences | 1 sequence NRLA_ACISA (P33036) | 
| PDB [Detailed view] | 3 PDB pdb_00006i00; pdb_00006i5t; pdb_00006i5u | 
