PROSITE entry PS00921

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00921
Entry name [info]	NITRIL_CHT_2
Accession [info]	PS00921
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00712
Associated ProRule [info]	PRU10105

Name and characterization of the entry

Description [info]	Nitrilases / cyanide hydratase active site signature.
Pattern [info]	G-[GAQ]-x(2)-C-[WA]-E-[NH]-x(2)-[PST]-[LIVMFYS]-x-[KR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	38 in 38 different sequences
Number of true positive hits	38 in 38 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	6
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	86.36 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 4
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	38 sequences CHT_ALTBR (Q7Z8M6), CHT_BOTF4 (G2XQT1), CHT_FUSSL (Q96UG7), CHT_GIBBA (P32963), CHT_GIBZE (I1RP53), CHT_LEPMC (Q9P8V3), CHT_MICSH (P32964), CHT_NEUCR (Q7RVT0), CHT_PYRTT (E3RV84), CHT_STEHR (P9WEU5), NIT1_ASPKW (G7XTA8), NIT1_ASPNC (A2R6M7), NIT1_YEAST (P40447), NIT2_ASPKW (G7X8S6), NIT2_ASPNC (A2RA31), NIT2_PENRW (B6HVR6), NITR1_BRADU (Q89GE3), NITR2_BRADU (Q89PT3), NITR_PARP8 (B2JQY2), NITR_PSEU2 (Q500U1), NIT_ASPOR (Q2U4D6), NIT_AURST (A0A0P1DJE3), NIT_MACPH (K2QXC4), NIT_SINF1 (G9AIU0), NIT_TALMQ (B6Q5I3), NRL1_ARATH (P32961), NRL1_RHORH (Q02068), NRL2_ARATH (P32962), NRL2_RHORH (Q03217), NRL3_ARATH (P46010), NRL4A_LUPAN (Q5QGZ8), NRL4A_TOBAC (Q42965), NRL4B_LUPAN (Q3LRV4), NRL4B_TOBAC (Q42966), NRL4_ARATH (P46011), NRL4_ORYSJ (Q6H849), NRLA_ALCFA (P20960), NRLB_KLEPO (P10045) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	6 sequences CHT_ASPNG (A9QXE0), CHT_EMENI (C8V9R7), CHT_PENRW (B6HCY4), NITR2_UNKP (Q6RWK4), NITR3_UNKP (Q6RWG0), NRL_BACSX (P82605) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence NRLA_ACISA (P33036)
PDB [Detailed view]	3 PDB 6I00; 6I5T; 6I5U