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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00922


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PURL: https://purl.expasy.org/prosite/signature/PS00922

Direct ScanProsite submission
General information about the entry

Entry name [info] TRANSGLYCOSYLASE
Accession [info] PS00922
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00713
Associated ProRule [info] PRU10071

Name and characterization of the entry

Description [info] Prokaryotic transglycosylases signature.
Pattern [info] 
[LIVM]-x(3)-E-S-x(3)-[AP]-x(3)-S-x(5)-G-[LIVM]-[LIVMFYW]-x-[LIVMFYW]-
x(4)-[SAG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 209 in 209 different sequences
Number of true positive hits 209 in 209 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 27
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 88.56 %

Comments [info]

Taxonomic range [info] Bacteriophages, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 209 sequences 

CWLQ_BACSU  (O31608), EMTAL_SHIFL (Q83RQ0), EMTA_CITK8  (A8AFS5), 

EMTA_CROS8  (A7MKC3), EMTA_ECO27  (B7UQ77), EMTA_ECO45  (B7MK90), 
EMTA_ECO55  (B7LGV3), EMTA_ECO57  (Q8XDJ7), EMTA_ECO5E  (B5YXL7), 
EMTA_ECO7I  (B7NUV4), EMTA_ECO81  (B7MTX1), EMTA_ECO8A  (B7LXA7), 
EMTA_ECOBW  (C4ZTN4), EMTA_ECODH  (B1XAN4), EMTA_ECOK1  (A1AAB6), 
EMTA_ECOL5  (Q0TII2), EMTA_ECOL6  (P59243), EMTA_ECOLC  (B1IU99), 
EMTA_ECOLI  (P0C960), EMTA_ECOLU  (B7N3Z9), EMTA_ECOSM  (B1LHX3), 
EMTA_ECOUT  (Q1RCQ2), EMTA_ENT38  (A4WBE8), EMTA_ESCF3  (B7LSJ1), 
EMTA_KLEP3  (B5XQ85), EMTA_KLEP7  (A6TAW0), EMTA_SALCH  (Q57NL3), 
EMTA_SALEP  (B5R2X1), EMTA_SALG2  (B5R901), EMTA_SALPA  (Q5PN08), 
EMTA_SALPB  (A9MVX1), EMTA_SALPC  (C0Q334), EMTA_SALPK  (B5BI54), 
EMTA_SALTI  (Q8XGT6), EMTA_SALTY  (Q7CQE4), EMTA_SHIBS  (Q31ZN3), 
EMTA_SHIDS  (Q32H22), EMTA_SHIF8  (Q0T5K7), EMTA_SHIFL  (Q83RP9), 
EMTA_SHISS  (Q3Z2V5), EXLYS_BPPRD (P27380), EXLYS_BPT7  (P03726), 
MLTC_ACTP2  (A3N339), MLTC_ACTP7  (B3GYW8), MLTC_ACTPJ  (B0BSH0), 
MLTC_ACTSZ  (A6VLS0), MLTC_CITK8  (A8API2), MLTC_CROS8  (A7MLX9), 
MLTC_ECO24  (A7ZR89), MLTC_ECO27  (B7UI10), MLTC_ECO45  (B7MN10), 
MLTC_ECO55  (B7LFM1), MLTC_ECO57  (Q8XCS6), MLTC_ECO5E  (B5YQG2), 
MLTC_ECO7I  (B7NI32), MLTC_ECO81  (B7MZB8), MLTC_ECO8A  (B7LYZ3), 
MLTC_ECOBW  (C5A0N2), MLTC_ECODH  (B1XFC3), MLTC_ECOHS  (A8A4A6), 
MLTC_ECOK1  (A1AFE9), MLTC_ECOL5  (Q0TDN8), MLTC_ECOL6  (P0C067), 
MLTC_ECOLC  (B1ISK6), MLTC_ECOLI  (P0C066), MLTC_ECOLU  (B7N7L9), 
MLTC_ECOSE  (B6I7A0), MLTC_ECOSM  (B1LDH3), MLTC_ECOUT  (Q1R762), 
MLTC_EDWI9  (C5BCE9), MLTC_ENT38  (A4WEA0), MLTC_ESCF3  (B7LPT3), 
MLTC_GLAP5  (B8F6F0), MLTC_HAEDU  (Q7VKB7), MLTC_HAEI8  (Q4QMD8), 
MLTC_HAEIE  (A5UDW4), MLTC_HAEIG  (A5UHR5), MLTC_HAEIN  (P44049), 
MLTC_HISS1  (Q0I513), MLTC_HISS2  (B0UWE6), MLTC_KLEP3  (B5XU88), 
MLTC_KLEP7  (A6TDX1), MLTC_MANSM  (Q65VT8), MLTC_PASMU  (Q9CLB8), 
MLTC_PECAS  (Q6D8K0), MLTC_PHOLL  (Q7N7I2), MLTC_SALAR  (A9MQR3), 
MLTC_SALCH  (Q57K03), MLTC_SALPA  (Q5PMM0), MLTC_SALPB  (A9N4R0), 
MLTC_SALTI  (Q8Z3T9), MLTC_SALTY  (Q8ZM39), MLTC_SERP5  (A8GJ50), 
MLTC_SHIB3  (B2U178), MLTC_SHIBS  (Q31WM5), MLTC_SHIDS  (Q32C32), 
MLTC_SHIF8  (Q0T0S4), MLTC_SHIFL  (Q83Q83), MLTC_SHISS  (Q3YXF0), 
MLTC_SODGM  (Q2NRB3), MLTC_YERE8  (A1JPV7), MLTC_YERP3  (A7FEX3), 
MLTC_YERPA  (Q1CB94), MLTC_YERPB  (B2K0V2), MLTC_YERPE  (Q8ZHE6), 
MLTC_YERPG  (A9R6R2), MLTC_YERPN  (Q1CEV1), MLTC_YERPP  (A4TI58), 
MLTC_YERPS  (Q666M2), MLTD_ECOL6  (P0AEZ8), MLTD_ECOLI  (P0AEZ7), 
MLTE_BUCAI  (P57352), MLTF1_ALKEH (Q0A9W6), MLTF2_ALKEH (Q0A9T8), 
MLTF_ACTP2  (A3N214), MLTF_ACTP7  (B3GYE5), MLTF_ACTPJ  (B0BQV5), 
MLTF_AERHH  (A0KJ50), MLTF_AERS4  (A4SNZ5), MLTF_ALCBS  (Q0VRG6), 
MLTF_ALIF1  (Q5E750), MLTF_CELJU  (B3PLH7), MLTF_CHRSD  (Q1QZB1), 
MLTF_CITK8  (A8AD27), MLTF_COLP3  (Q47XX8), MLTF_DESOH  (A8ZWR8), 
MLTF_ECO11  (B3Y154), MLTF_ECO24  (A7ZQ01), MLTF_ECO57  (Q8XA45), 
MLTF_ECODH  (B1XB33), MLTF_ECOHS  (A8A366), MLTF_ECOK1  (A1AE89), 
MLTF_ECOL5  (Q0TET0), MLTF_ECOL6  (Q8FF25), MLTF_ECOLC  (B1IVR9), 
MLTF_ECOLI  (P0AGC5), MLTF_ECOSM  (B1LP71), MLTF_ECOUT  (Q1R8H6), 
MLTF_ECTM1  (A4XXV1), MLTF_ENT38  (A4WDC7), MLTF_ERWT9  (B2VEB4), 
MLTF_HAEDU  (Q7VN03), MLTF_HAEI8  (Q4QNV4), MLTF_HAEIE  (A5UAQ3), 
MLTF_HAEIG  (A5UG36), MLTF_HAEIN  (P44587), MLTF_HAHCH  (Q2SK06), 
MLTF_HISS1  (Q0I361), MLTF_HISS2  (B0UUK3), MLTF_IDILO  (Q5QWY4), 
MLTF_KLEP7  (A6TCH2), MLTF_MARN8  (A1U3J1), MLTF_NITMU  (Q2Y6L9), 
MLTF_PASMU  (Q9CPJ2), MLTF_PECAS  (Q6D237), MLTF_PHOPR  (Q6LU25), 
MLTF_PSE14  (Q48LX4), MLTF_PSEAB  (Q02RN8), MLTF_PSEAE  (Q9HXN1), 
MLTF_PSEE4  (Q1I5L3), MLTF_PSEF5  (Q4KHS7), MLTF_PSEP1  (A5VZC8), 
MLTF_PSEP7  (A6V102), MLTF_PSEPF  (Q3KHL5), MLTF_PSEPG  (B0KRE9), 
MLTF_PSEPK  (Q88P17), MLTF_PSEPW  (B1JDH3), MLTF_PSESM  (Q886W7), 
MLTF_PSET1  (Q3IHZ1), MLTF_PSEU2  (Q4ZX03), MLTF_SALAR  (A9MGY7), 
MLTF_SALCH  (Q57LE4), MLTF_SALPA  (Q5PIH0), MLTF_SALPB  (A9N1U5), 
MLTF_SALTI  (Q8Z4L5), MLTF_SALTY  (Q8ZN28), MLTF_SERP5  (A8GI11), 
MLTF_SHIB3  (B2TXX1), MLTF_SHIBS  (Q31XS9), MLTF_SHIDS  (Q32D14), 
MLTF_SHIF8  (Q0T1W2), MLTF_SHIFL  (P0AGC6), MLTF_SHISS  (Q3YYZ7), 
MLTF_SODGM  (Q2NS21), MLTF_STUS1  (A4VP14), MLTF_SULDN  (Q30PQ0), 
MLTF_VIBC1  (A7MSG2), MLTF_VIBC3  (A5F353), MLTF_VIBCH  (Q9KTN5), 
MLTF_VIBPA  (Q87RW1), MLTF_VIBVU  (Q8DF80), MLTF_VIBVY  (Q7MN72), 
MLTF_YERE8  (A1JKM2), MLTF_YERP3  (A7FFU9), MLTF_YERPA  (Q1C5E6), 
MLTF_YERPB  (B2KA37), MLTF_YERPE  (Q74SQ6), MLTF_YERPG  (A9R413), 
MLTF_YERPN  (Q1CKD3), MLTF_YERPP  (A4TMX8), MLTF_YERPS  (Q667W0), 
MLTF_YERPY  (B1JRW4), SLT_ECO57   (P0AGC4), SLT_ECOLI   (P0AGC3), 
SLT_HAEIN   (P44888), SLT_SALTY   (P39434), TBTA_ALTSM  (P32820), 
TMP_BPSPB   (O64046), YOMI_BACSU  (O31976)
» more

UniProtKB/Swiss-Prot
False negative sequences		 27 sequences 

MLTE_BUCBP  (Q89AM2), MLTF_ACTSZ  (A6VMD7), MLTF_ALTMD  (B4RVK5), 

MLTF_CROS8  (A7MGZ5), MLTF_MAGMM  (A0L862), MLTF_MANSM  (Q65RJ5), 
MLTF_MARMM  (Q0AQY9), MLTF_METFK  (Q1H288), MLTF_SACD2  (Q21KP0), 
MLTF_SHEAM  (A1S850), MLTF_SHEB5  (A3D6V0), MLTF_SHEB8  (A6WQN7), 
MLTF_SHEB9  (A9KWW4), MLTF_SHEDO  (Q12PR8), MLTF_SHEFN  (Q085S2), 
MLTF_SHEHH  (B0TLJ6), MLTF_SHELP  (A3QCH2), MLTF_SHEON  (Q8EC56), 
MLTF_SHEPA  (A8H256), MLTF_SHEPC  (A4Y8T1), MLTF_SHESA  (A0KUK5), 
MLTF_SHESH  (A8FY01), MLTF_SHESM  (Q0HKV0), MLTF_SHESR  (Q0HX48), 
MLTF_SHESW  (A1RHR2), MLTF_SHEWM  (B1KLC4), MLTF_THIDA  (Q3SJH8)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

SLT_ENTCL   (P39433)


				
	

	

		PDB
[Detailed view]		
		
			22 PDB
			


			pdb_00001qsa; pdb_00001qte; pdb_00001sly; pdb_00002y8p; pdb_00003t36; pdb_00004c5f; pdb_00004hjv; pdb_00004owd; pdb_00004oyv; pdb_00004oz9; pdb_00004p0g; pdb_00004p11; 
			
				pdb_00005a5x; pdb_00005aa1; pdb_00005aa2; pdb_00005aa3; pdb_00006ghz; pdb_00006gi4; pdb_00006yt5; pdb_00007eyb; pdb_00007k5c; pdb_00009jyy
			
			

			» more