PROSITE entry PS00947

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00947
Entry name [info]	CATHELICIDINS_2
Accession [info]	PS00947
Entry type [info]	PATTERN
Date [info]	01-JUN-1994 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00729

Name and characterization of the entry

Description [info]	Cathelicidins signature 2.
Pattern [info]	F-x-[LIVM]-K-E-T-x-C-x(10)-C-x-F-[KR]-[KE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	49 in 49 different sequences
Number of true positive hits	49 in 49 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	7
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	87.50 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Site [info]	disulfide at position 8
Site [info]	disulfide at position 10
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	49 sequences CAMP_ATEFR (Q1KLY8), CAMP_ATEFU (Q1KLY7), CAMP_CALJA (Q1KLY4), CAMP_CEBCA (Q1KLY5), CAMP_CHLAE (Q1KLY6), CAMP_GORGO (Q1KLY3), CAMP_HUMAN (P49913), CAMP_HYLML (Q1KLX8), CAMP_MACFA (Q1KLX7), CAMP_MACMU (Q9GLV5), CAMP_MACTO (Q1KLX6), CAMP_MOUSE (P51437), CAMP_NOMCO (Q1KLY0), CAMP_NOMGA (Q1KLY2), CAMP_NOMLE (Q1KLX9), CAMP_PANTR (Q1KLX1), CAMP_PAPPA (Q1KLX3), CAMP_PONPY (Q1KLX2), CAMP_SAGOE (Q1KLX0), CAMP_TRACR (Q1KLX5), CAMP_TRAOB (Q1KLX4), CAP18_RABIT (P25230), CTHL1_BOVIN (P22226), CTHL1_SHEEP (P54230), CTHL2_BOVIN (P19660), CTHL2_CAPHI (P82018), CTHL2_SHEEP (P79362), CTHL3_BOVIN (P19661), CTHL3_SHEEP (P50415), CTHL4_BOVIN (P33046), CTHL5_BOVIN (P54229), CTHL6_BOVIN (P54228), CTHL7_BOVIN (P56425), ICTL_PIG(P15175), P15A_RABIT (P26202), P15B_RABIT (P26203), PF11_PIG(P51524), PF12_PIG(P51525), PG1_PIG (P32194), PG2_PIG (P32195), PG3_PIG (P32196), PG4_PIG (P49933), PG5_PIG (P49934), PMP23_PIG (P49930), PMP36_PIG (P49931), PMP37_PIG (P49932), PR39_PIG(P80054), SC51_SHEEP (P49928), SC52_SHEEP (P49929) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	7 sequences CAMP_BUNFA (B6D434), CAMP_NAJAT (B6S2X0), CAMP_OPHHA (B6S2X2), CTHB1_CHICK (Q5F378), CTHL1_CHICK (Q6QLQ5), CTHL2_CHICK (Q2IAL7), CTHL3_CHICK (Q2IAL6) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence CTHL3_CAPHI (P85170)
PDB [Detailed view]	5 PDB 1KWI; 1LXE; 1N5H; 1N5P; 4EYC