We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE entry PS00958
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PURL: https://purl.expasy.org/prosite/signature/PS00958
Direct ScanProsite submission
General information about the entry
| Entry name [info] | TRANSALDOLASE_2 |
| Accession [info] | PS00958 |
| Entry type [info] | PATTERN |
| Date [info] |
01-JUN-1994 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00741 |
| Associated ProRule [info] | PRU10019 |
Name and characterization of the entry
| Description [info] | Transaldolase active site. |
| Pattern [info] |
[LIVMA]-x-[LIVM]-K-[LIVM]-[PAS]-x-[STC]-x-[DENQPAS]-[GC]-[LIVM]-x-[AGV]- x(0,1)-[QEKRSTH]-x-[LIVMF]. |
Numerical results [info]
| Total number of hits | 403 in 403 different sequences |
| Number of true positive hits | 403 in 403 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 93 |
| Number of 'partial' sequences | 4 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 81.25 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 4 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
403 sequences
FSAA_ECO57 (P58423), FSAA_ECOL6 (Q8FJL3), FSAA_ECOLI (P78055), FSAB_ECO57 (P58424), FSAB_ECOL6 (Q8FBA7), FSAB_ECOLI (P32669), FSA_ENT38 (A4W8H0), FSA_KLEP3 (B5XZ23), FSA_KLEP7 (A6TGD7), FSA_SALA4 (B5F0U2), FSA_SALAR (A9MI17), FSA_SALCH (Q57HA5), FSA_SALDC (B5FPW2), FSA_SALEP (B5QXP2), FSA_SALG2 (B5RF58), FSA_SALHS (B4TCP9), FSA_SALNS (B4T0V8), FSA_SALPA (Q5PK58), FSA_SALPB (A9N0F4), FSA_SALPC (C0Q463), FSA_SALPK (B5BJM7), FSA_SALTI (Q8Z305), FSA_SALTY (Q8ZKM8), FSA_STRPJ (B8ZKS3), FSA_STRPN (Q97SS2), TAL1_BACAN (Q81V33), TAL1_BACCR (Q81HW6), TAL1_FUSO4 (J9MJK9), TAL1_GIBIN (A0A075DVI9), TAL1_KLULA (P34214), TAL1_LISIN (Q927A3), TAL1_LISMF (Q71W21), TAL1_LISMO (Q8Y3T8), TAL1_PECAS (Q6D8W0), TAL1_SALCH (Q57TP8), TAL1_SALPA (Q5PDM6), TAL1_SCHPO (O42700), TAL1_SHISS (Q3Z606), TAL1_STRAW (Q82M93), TAL1_STRCO (O88018), TAL1_YEAST (P15019), TAL2_BACAN (Q81MY9), TAL2_BACCR (Q81B21), TAL2_LISIN (P66958), TAL2_LISMF (Q723W2), TAL2_LISMO (P66957), TAL2_NOSP7 (P48983), TAL2_NOSS1 (P48993), TAL2_PECAS (Q6D0B2), TAL2_SALCH (Q57LN7), TAL2_SHISS (Q3YZ89), TAL2_YEAST (P53228), TALA_ECO57 (P0A869), TALA_ECOL6 (P0A868), TALA_ECOLI (P0A867), TALA_PASMU (Q9CKL0), TALA_SALTI (Q8Z4T0), TALA_SHIFL (Q83QM8), TALB_ECO1E (K0BE10), TALB_ECO57 (P0A871), TALB_ECOL6 (Q8FLD1), TALB_ECOLI (P0A870), TALB_PASMU (Q9CKH9), TALB_SALTI (P66956), TALB_SALTY (P66955), TALB_SHIFL (P0A872), TALDO_BOVIN (Q2TBL6), TALDO_CRIGR (Q8VI73), TALDO_DICDI (Q54UP4), TALDO_DROME (Q9W1G0), TALDO_HUMAN (P37837), TALDO_MOUSE (Q93092), TALDO_PIG (Q29593), TALDO_RAT (Q9EQS0), TAL_ACIC5 (C1F2H6), TAL_ACIET (B9MDC2), TAL_ACISJ (A1W3W5), TAL_ACTP2 (A3MYD4), TAL_ACTP7 (B3GZQ2), TAL_ACTPJ (B0BRM0), TAL_ACTSZ (A6VLW0), TAL_AERS4 (A4SK74), TAL_AGARV (C4ZF71), TAL_AGRFC (Q8U7I5), TAL_ALBFT (Q21ZD6), TAL_ALIF1 (Q5DZP1), TAL_ALIFM (B5EUF3), TAL_ALISL (B6ERE2), TAL_ALKMQ (A6TK31), TAL_ALKOO (A8MJZ5), TAL_ALLAM (B9JST0), TAL_ALTMD (B4RX40), TAL_ANAD2 (B8JAM9), TAL_ANADE (Q2IGW6), TAL_ANASK (B4UHE7), TAL_BACC1 (Q73DH4), TAL_BACCN (A7GLA6), TAL_BACCZ (Q63FX6), TAL_BACHK (Q6HNE4), TAL_BACP2 (A8FIE1), TAL_BACSU (P19669), TAL_BACVZ (A7Z9T0), TAL_BARBK (A1UR41), TAL_BARHE (Q6G1W4), TAL_BARQU (Q6FYL8), TAL_BART1 (A9IYY3), TAL_BAUCH (Q1LU10), TAL_BDEBA (Q6MRM6), TAL_BLOFL (Q7VRT4), TAL_BORA1 (Q2KVT3), TAL_BORBR (Q7WME6), TAL_BORPA (Q7WAY2), TAL_BORPE (Q7VY99), TAL_BRAHW (C0QVC8), TAL_BREBN (C0Z838), TAL_BRUA1 (B2S7M9), TAL_BRUA2 (Q2YLI1), TAL_BRUA4 (A6WXW5), TAL_BRUAB (Q57B82), TAL_BRUC2 (A9M843), TAL_BRUMB (C0RF56), TAL_BRUME (Q8YJ42), TAL_BRUO2 (A5VSE7), TAL_BRUSI (A9WWS9), TAL_BRUSU (Q8FYQ9), TAL_BUCA5 (B8D8P5), TAL_BUCAI (P57194), TAL_BUCAP (Q8KA27), TAL_BUCAT (B8D6Z9), TAL_BUCCC (Q058B4), TAL_BURA4 (B1YU93), TAL_BURCH (A0K9A9), TAL_BURCJ (B4E6F9), TAL_BURCM (Q0BD43), TAL_BURL3 (Q39E45), TAL_BURM1 (A9AIJ8), TAL_BURM7 (A3MHY5), TAL_BURMA (Q62ID7), TAL_BURMS (A1V2A0), TAL_BURO0 (B1JW82), TAL_BURO1 (Q1BUS8), TAL_BURP0 (A3NSY2), TAL_BURP1 (Q3JUL7), TAL_BURP6 (A3N794), TAL_BURPS (Q63W00), TAL_BURTA (Q2SZY3), TAL_BURVG (A4JGM1), TAL_CALBD (B9MJS9), TAL_CALS8 (A4XL36), TAL_CARHZ (Q3AFT3), TAL_CELJU (B3PDM9), TAL_CERS1 (A3PLV0), TAL_CERS4 (Q3J0F0), TAL_CERS5 (A4WRW1), TAL_CERSK (B9KKW2), TAL_CHESB (Q11DE1), TAL_CHLAB (Q5L5I5), TAL_CHLCV (Q822J3), TAL_CHLFF (Q255E4), TAL_CHLMU (Q9PK80), TAL_CHLPN (Q9Z998), TAL_CHLT3 (B3QRS6), TAL_CHLTA (Q3KM49), TAL_CHLTR (O84315), TAL_CHRSD (Q1QZV1), TAL_CITBB (B5ED52), TAL_CLOAB (Q97JD9), TAL_CLOB1 (A7FTH1), TAL_CLOB6 (C3KTY4), TAL_CLOBH (A5I1C9), TAL_CLOBJ (C1FL18), TAL_CLOBK (B1IJR0), TAL_CLOBL (A7GCY3), TAL_CLOBM (B1L010), TAL_CLOD6 (Q185K3), TAL_CLOK1 (B9E0C8), TAL_CLOK5 (A5N6V9), TAL_CLOP1 (Q0TTA4), TAL_CLOPE (Q8XMJ6), TAL_CLOPS (Q0SV41), TAL_CLOTE (Q899F3), TAL_COLP3 (Q47WR3), TAL_COPPD (B5Y9V1), TAL_CUPMC (Q1LLK8), TAL_CUPNH (Q0K979), TAL_CUPPJ (Q46ZK0), TAL_CUPTR (B3R1I4), TAL_DEIRA (Q9RUP6), TAL_DELAS (A9BXM7), TAL_DESAH (C0QIA5), TAL_DESHD (B8FZ81), TAL_DESHY (Q24ML5), TAL_DESOH (A8ZW56), TAL_DESPS (Q6AR67), TAL_DINSH (A8LNY7), TAL_ECTM1 (A4XTM7), TAL_EDWI9 (C5B7L0), TAL_EXISA (C4KYW2), TAL_FERNB (A7HME3), TAL_FLAPJ (A6GYG9), TAL_GEODF (B9M1X7), TAL_GEOKA (Q5KUG6), TAL_GEOMG (Q39YD4), TAL_GEOSM (C6E082), TAL_GEOSW (C5D9P4), TAL_GEOTN (A4ITL5), TAL_GEOUR (A5GBY8), TAL_GLAP5 (B8F5Q3), TAL_GLOVI (Q7NK81), TAL_HAEDU (Q7VP02), TAL_HAEI8 (Q4QLG9), TAL_HAEIE (A5UCY0), TAL_HAEIG (A5UIP9), TAL_HAEIN (P45055), TAL_HALH5 (Q9K6E4), TAL_HAMD5 (C4K4G2), TAL_HELPH (Q1CRD7), TAL_HELPS (B2UVP1), TAL_HELPY (P56108), TAL_HISS1 (Q0I1U0), TAL_HISS2 (B0UV30), TAL_HYPNA (Q0BX85), TAL_JANSC (Q28TL3), TAL_KOSOT (C5CGH2), TAL_LACP7 (A9KPQ3), TAL_LACPL (Q88S98), TAL_LYSSC (B1I057), TAL_MANSM (Q65PZ8), TAL_MARMM (Q0AQJ7), TAL_MARN8 (A1U1Y1), TAL_MARSD (C6C0W4), TAL_METAM (Q9S0X4), TAL_METFK (Q1H0R4), TAL_METJA (Q58370), TAL_METPP (A2SKF9), TAL_MYCBO (P59955), TAL_MYCBP (A1KIN7), TAL_MYCBT (C1AN93), TAL_MYCLB (B8ZUQ2), TAL_MYCLE (P55193), TAL_MYCPA (Q741B5), TAL_MYCS2 (A0QWX9), TAL_MYCTA (A5U2F1), TAL_MYCTO (P9WG32), TAL_MYCTU (P9WG33), TAL_NATTJ (B2A3J5), TAL_NEIG1 (Q5F6E9), TAL_NEIG2 (B4RJ66), TAL_NEIM0 (A9M2N9), TAL_NEIMA (Q9JSU1), TAL_NEIMB (Q9K139), TAL_NEIMF (A1KVT3), TAL_NITMS (A9A413), TAL_NOSP7 (B2J2D9), TAL_NOSS1 (P58561), TAL_OCEIH (Q8CX76), TAL_OPITP (B1ZUE6), TAL_PARC0 (A1TKQ3), TAL_PARDP (A1B4Z2), TAL_PARMW (Q7U5E8), TAL_PARP8 (B2JE74), TAL_PARPJ (B2T236), TAL_PARXL (Q142S4), TAL_PELPD (A1AKQ8), TAL_PELTS (A5CYD0), TAL_PERMH (C0QPV2), TAL_PHEZH (B4RB97), TAL_PHOLL (Q7N8Z1), TAL_PHOPR (Q6LLF0), TAL_PICTO (Q6L178), TAL_POLNA (A1VJZ5), TAL_POLSJ (Q12FI4), TAL_PORG3 (B2RHK7), TAL_PORGI (Q7MXG0), TAL_PROM0 (A3PBP3), TAL_PROM1 (A2C0X8), TAL_PROM4 (A9BEE2), TAL_PROM5 (A2BVI1), TAL_PROM9 (Q31C15), TAL_PROMA (Q7VD64), TAL_PROMH (B4F2V2), TAL_PROMM (Q7V6B8), TAL_PROMP (Q7V2G1), TAL_PROMT (Q46GQ7), TAL_PSE14 (Q48KH5), TAL_PSEA6 (Q15PR4), TAL_PSEA8 (B7UWP0), TAL_PSEAB (Q02NV3), TAL_PSEAE (Q9I047), TAL_PSEE4 (Q1I7G7), TAL_PSEF5 (Q4KF90), TAL_PSELT (A8F6A5), TAL_PSEP7 (A6V3U3), TAL_PSEPF (Q3K9H0), TAL_PSEPG (B0KHA7), TAL_PSEPK (Q88KX1), TAL_PSEPW (B1J623), TAL_PSESM (Q884H4), TAL_PSEU2 (Q4ZV64), TAL_RHIE6 (B3Q0T5), TAL_RHIEC (Q2K414), TAL_RHILO (Q98EV0), TAL_RHILW (B5ZQY2), TAL_RHIME (Q92LK3), TAL_RHIR8 (B9JAX6), TAL_RHOCS (B6IPE0), TAL_RHORT (Q2RUN7), TAL_ROSCS (A7NGG1), TAL_ROSDO (Q168B1), TAL_ROSS1 (A5V243), TAL_RUEPO (Q5LNS5), TAL_RUEST (Q1GE05), TAL_SACEN (A4FBP0), TAL_SHEAM (A1S414), TAL_SHEB2 (B8EFD7), TAL_SHEB5 (A3D1F5), TAL_SHEB8 (A6WKC4), TAL_SHEB9 (A9L4T6), TAL_SHEDO (Q12KL3), TAL_SHEFN (Q07Z25), TAL_SHEHH (B0TJA0), TAL_SHELP (A3QBW2), TAL_SHEON (Q8EBH2), TAL_SHEPA (A8H1G4), TAL_SHEPC (A4Y494), TAL_SHEPW (B8CSD3), TAL_SHESA (A0L002), TAL_SHESH (A8FSH3), TAL_SHESM (Q0HFX9), TAL_SHESR (Q0HS72), TAL_SHESW (A1RMN6), TAL_SHEWM (B1KIS4), TAL_SHIBS (Q326L3), TAL_SHIDS (Q32KB0), TAL_SHOC1 (Q5WB47), TAL_SINFN (C3M9S7), TAL_SINMW (A6UDM7), TAL_SODGM (Q2NS86), TAL_STRA3 (Q8E3B1), TAL_STRA5 (Q8DXP1), TAL_STRE4 (C0M7L5), TAL_STREM (B4U4L6), TAL_STRP1 (P66959), TAL_STRP3 (P0DG12), TAL_STRP6 (Q5XAK4), TAL_STRP8 (P66961), TAL_STRPB (Q1JAF7), TAL_STRPC (Q1JKK8), TAL_STRPD (Q1JFK0), TAL_STRPF (Q1J5E9), TAL_STRPG (A2RD32), TAL_STRPM (Q48RY1), TAL_STRPQ (P0DG13), TAL_STRPZ (B5XMM1), TAL_STRS7 (C0MGU8), TAL_STUS1 (A4VK43), TAL_SULSY (B2V7E1), TAL_SYNC1 (Q3A7Y3), TAL_SYNFM (A0LEA2), TAL_SYNP6 (Q5N127), TAL_SYNWW (Q0AUA5), TAL_SYNY3 (P72797), TAL_TERTT (C5BLR8), TAL_THEAB (B7IE29), TAL_THEAC (Q9HKI3), TAL_THEM4 (A6LNG2), TAL_THEMA (Q9WYD1), TAL_THEP1 (A5IKB4), TAL_THESQ (B1L9J1), TAL_THET2 (Q72JR7), TAL_THET8 (Q5SJE8), TAL_THEVB (Q8DLL7), TAL_THEVO (Q97AZ4), TAL_THIDA (Q3SL03), TAL_THISH (B8GMX9), TAL_TRIEI (Q118F4), TAL_TRIL1 (B3E1K9), TAL_TRIV2 (P51778), TAL_VARPS (C5CPN2), TAL_VEREI (A1WIS6), TAL_VIBC1 (A7N1Z7), TAL_VIBC3 (A5F028), TAL_VIBCH (Q9KLW8), TAL_VIBCM (C3LVN8), TAL_VIBPA (Q87GY5), TAL_VIBVU (Q8D6H9), TAL_VIBVY (Q7MDD5), TAL_WIGBR (Q8D1X3), TAL_XANAC (Q8PNY6), TAL_XANC8 (Q4UR79), TAL_XANCB (B0RUE4), TAL_XANCP (Q8PCA4), TAL_XANE5 (Q3BX43), TAL_XANOM (Q2NZS1), TAL_XANOP (B2SQJ4), TAL_XANOR (Q5GWL8), TAL_YERE8 (A1JJD0), TAL_YERP3 (A7FME9), TAL_YERPB (B2K3L5), TAL_YERPE (Q8ZIN2), TAL_YERPG (A9R021), TAL_YERPS (Q66ET5), TAL_YERPY (B1JL09)» more
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| UniProtKB/Swiss-Prot False negative sequences |
93 sequences
FSA_SALSV (B4TQG9), SFTAL_PRIAR (A0A7W3N5X5), SFTAL_PRIM1 (D5E1T2), TAL2_SALPA (Q5PCU4), TAL2_STRAW (Q829U5), TAL2_STRCO (Q9XAC0), TALA_SALTY (Q8ZN83), TAL_ACIC1 (A0LTY8), TAL_ANADF (A7H783), TAL_AQUAE (O66520), TAL_ARTS2 (A0JWQ6), TAL_BACFN (Q5LAU6), TAL_BACFR (Q64R94), TAL_BACTN (Q8A767), TAL_BORPD (A9HYZ1), TAL_BUCBP (Q89AY3), TAL_CALS4 (Q8R8S6), TAL_CAMJ8 (A8FK69), TAL_CAMJD (A7H591), TAL_CAMJE (Q9PIL5), TAL_CAMJJ (A1VY04), TAL_CAMJR (Q5HWI6), TAL_CAUSK (B0T583), TAL_CAUVC (Q9A2F1), TAL_CAUVN (B8H6D3), TAL_CHLCH (Q3ANX8), TAL_CHLL2 (B3EII6), TAL_CHLL3 (Q3B151), TAL_CHLP8 (B3QLU3), TAL_CHLPB (B3EQ72), TAL_CHLPD (A1BJV5), TAL_CHLPM (A4SGX9), TAL_CHLTE (Q8KGF8), TAL_CLOBA (B2V0J9), TAL_CLOBB (B2TKE5), TAL_CLONN (A0Q3L2), TAL_CYTH3 (Q11S31), TAL_DEHM1 (Q3Z6N2), TAL_DESAL (B8FH38), TAL_DESAP (B1I6H9), TAL_DESRM (A4J9C4), TAL_DICTD (B8E200), TAL_ERYLH (Q2N908), TAL_EXIS2 (B1YEL0), TAL_FRAAA (Q0RH18), TAL_FRACC (Q2JCG8), TAL_GEOSL (Q748M4), TAL_HELMI (B0TI77), TAL_HELP2 (B6JNZ3), TAL_HELPJ (Q9ZJC5), TAL_HERA2 (A9AZ03), TAL_HYDS0 (B4U8P1), TAL_KOCRD (B2GH92), TAL_LEIXX (Q6AF36), TAL_LEPBA (B0SGW0), TAL_LEPBJ (Q04T59), TAL_LEPBL (Q051I1), TAL_LEPBP (B0SQ07), TAL_LEPCP (B1Y2Y8), TAL_LEPIC (Q72RT8), TAL_LEPIN (Q8F3W3), TAL_MARMS (A6VYA4), TAL_META3 (A6UTP5), TAL_METCA (Q602L8), TAL_METM5 (A4FWM6), TAL_METM6 (A9AA06), TAL_METM7 (A6VGP5), TAL_METMP (Q6LXP1), TAL_METVS (A6UPV2), TAL_MOOTA (Q2RFV4), TAL_MYCMM (B2HP98), TAL_MYCUA (A0PPP5), TAL_MYXXD (Q1CZW4), TAL_NOVAD (Q2G5P7), TAL_PARD8 (A6LG93), TAL_PARL1 (A7HT46), TAL_PARS2 (A8KYS5), TAL_PARUW (Q6MAI4), TAL_PELPB (B4SH30), TAL_PETMO (A9BHK7), TAL_PHOV8 (A6L5J5), TAL_PROA2 (B4S6D0), TAL_PSECP (B8H7N3), TAL_RALN1 (Q8Y014), TAL_RALPJ (B2U9W5), TAL_RENSM (A9WT40), TAL_RHIWR (A5V2S4), TAL_SORC5 (A9GI16), TAL_SPHAL (Q1GS53), TAL_SYMTH (Q67TE2), TAL_THEFY (Q47ND3), TAL_THEPX (B0K6D2), TAL_THEYD (B5YHV2)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
4 sequences
TAL1_CYBJA (P17440), TAL3_CYBJA (P17441), TALDO_CAPAA (P86071), TALDO_CARMA (P80427)» more |
| PDB [Detailed view] |
52 PDB
pdb_00001f05; pdb_00001i2n; pdb_00001i2o; pdb_00001i2p; pdb_00001i2q; pdb_00001i2r; pdb_00001l6w; pdb_00001onr; pdb_00001ucw; pdb_00001vpx; pdb_00001wx0; pdb_00002cwn; pdb_00002e1d; pdb_00003clm; pdb_00003cq0; pdb_00003cwn; pdb_00003hjz; pdb_00003kof; pdb_00003r8r; pdb_00003s0c; pdb_00003s1u; pdb_00003s1v; pdb_00003s1x; pdb_00004rxf; pdb_00004rxg; pdb_00004rz4; pdb_00004rz5; pdb_00004rz6; pdb_00004s1f; pdb_00004s2b; pdb_00004s2c; pdb_00004xz9; pdb_00005zol; pdb_00006yr3; pdb_00006yre; pdb_00006yrh; pdb_00006yrm; pdb_00006yrt; pdb_00006ys0; pdb_00006zwf; pdb_00006zwh; pdb_00006zwj; pdb_00006zx4; pdb_00007b0l; pdb_00007bbw; pdb_00007bbx; pdb_00007odo; pdb_00007odp; pdb_00007odq; pdb_00007oey; pdb_00007qxf; pdb_00008s7h » more |