PROSITE logo

PROSITE entry PS00972


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] USP_1
Accession [info] PS00972
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-DEC-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10092

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 1.
Pattern [info]
G-[LIVMFY]-x(1,3)-[AGCY]-[NASMQG]-x-C-[FYWC]-[LIVMFCA]-[NSTAD]-[SACV]-x-
[LIVMSF]-[QF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 297 in 297 different sequences
Number of true positive hits 297 in 297 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 29
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.10 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
297 sequences

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5), 
CREB_ASPFU  (Q4WQI1), CREB_ASPNC  (A2Q9N1), CREB_ASPOR  (Q2UUG8), 
CREB_ASPTN  (Q0CT11), CREB_EMENI  (Q96V54), CREB_NEOFI  (A1CW53), 
CYLD_BOVIN  (Q1RMU2), CYLD_HUMAN  (Q9NQC7), CYLD_MOUSE  (Q80TQ2), 
CYLD_PONAB  (Q5RED8), CYLD_RAT(Q66H62), FAF_DROME   (P55824), 
FLA_ORYSJ   (Q2R4I5), NOT_DROME   (Q9VVR1), PUF_DROME   (Q9VC56), 
U17L5_HUMAN (A8MUK1), U17L6_HUMAN (Q6QN14), U17L8_HUMAN (P0C7I0), 
U17LA_HUMAN (C9JJH3), U17LB_HUMAN (C9JVI0), U17LC_MOUSE (G5E8I7), 
U17LD_HUMAN (C9JLJ4), U17LF_HUMAN (C9J2P7), U17LH_HUMAN (D6RBQ6), 
U17LI_HUMAN (D6R9N7), U17LJ_HUMAN (D6RCP7), U17LK_HUMAN (D6RJB6), 
U17LL_HUMAN (D6R901), U17LM_HUMAN (D6RA61), U17LN_HUMAN (D6RBM5), 
U17LO_HUMAN (Q0WX57), U17PA_MOUSE (Q61068), U17PB_MOUSE (E9Q9U0), 
U17PD_MOUSE (G5E8G2), U17PE_MOUSE (Q7M764), UB10A_XENLA (Q2NL57), 
UB10B_XENLA (Q7ZXR7), UB12A_XENLA (Q52KZ6), UB12B_XENLA (Q5M981), 
UB22A_XENLA (Q6GNI6), UB22B_XENLA (Q6DCJ1), UBP10_ARATH (Q9ZSB5), 
UBP10_BOVIN (A5PJS6), UBP10_CHICK (Q5ZJN4), UBP10_HUMAN (Q14694), 
UBP10_MOUSE (P52479), UBP10_RAT   (Q3KR59), UBP10_XENTR (Q6DIJ4), 
UBP11_ARATH (Q9MAQ3), UBP11_HUMAN (P51784), UBP11_MOUSE (Q99K46), 
UBP11_RAT   (Q5D006), UBP11_YEAST (P36026), UBP12_ARATH (Q9FPT1), 
UBP12_BOVIN (A5D9H7), UBP12_DANRE (A4FUN7), UBP12_HUMAN (O75317), 
UBP12_MOUSE (Q9D9M2), UBP12_SALSA (C0HB46), UBP12_SCHPO (O60079), 
UBP12_YEAST (P39538), UBP13_ARATH (Q84WU2), UBP13_BOVIN (E1BMF7), 
UBP13_CHICK (E1BY77), UBP13_HUMAN (Q92995), UBP13_MOUSE (Q5BKP2), 
UBP13_YEAST (P38187), UBP14_ARATH (Q8L6Y1), UBP14_BOVIN (Q0IIF7), 
UBP14_CAEEL (Q17361), UBP14_HUMAN (P54578), UBP14_MOUSE (Q9JMA1), 
UBP14_PANTR (P60051), UBP14_RABIT (P40826), UBP14_SCHPO (Q11119), 
UBP14_YEAST (P38237), UBP15_ARATH (Q9FPS9), UBP15_BOVIN (Q2HJE4), 
UBP15_HUMAN (Q9Y4E8), UBP15_MOUSE (Q8R5H1), UBP15_ORYSJ (Q0E2F9), 
UBP15_RAT   (Q9R085), UBP15_XENTR (F6Z5C0), UBP15_YEAST (P50101), 
UBP16_ARATH (Q9SB51), UBP16_BOVIN (Q08DA3), UBP16_DANRE (A8HAL1), 
UBP16_EMENI (P0CAQ1), UBP16_HUMAN (Q9Y5T5), UBP16_MACFA (Q4R6X7), 
UBP16_MOUSE (Q99LG0), UBP16_RAT   (Q2KJ09), UBP16_SCHPO (O74442), 
UBP16_XENLA (Q6PAW2), UBP16_XENTR (Q0VA64), UBP16_YEAST (Q02863), 
UBP17_ARATH (Q9FKP5), UBP18_ARATH (Q67XW5), UBP18_HUMAN (Q9UMW8), 
UBP18_MOUSE (Q9WTV6), UBP18_PONAB (Q5RE63), UBP19_ARATH (Q9SJA1), 
UBP19_HUMAN (O94966), UBP19_MOUSE (Q3UJD6), UBP19_RAT   (Q6J1Y9), 
UBP1_ARATH  (Q9FPT5), UBP1_BOVIN  (Q29RP1), UBP1_HUMAN  (O94782), 
UBP1_MOUSE  (Q8BJQ2), UBP1_RAT(Q569C3), UBP1_SCHPO  (Q9USM5), 
UBP1_YEAST  (P25037), UBP20_ARATH (Q9FPS7), UBP20_BOVIN (A7Z056), 
UBP20_DANRE (A5PN09), UBP20_HUMAN (Q9Y2K6), UBP20_MOUSE (Q8C6M1), 
UBP20_PONAB (Q5R5Z6), UBP20_XENLA (B1WBD7), UBP20_XENTR (A0JM59), 
UBP21_ARATH (Q9FIQ1), UBP21_BOVIN (Q2KJ72), UBP21_HUMAN (Q9UK80), 
UBP21_MOUSE (Q9QZL6), UBP21_RAT   (B2GUX4), UBP22_ARATH (Q9LEW0), 
UBP22_BOVIN (P0C8Z3), UBP22_DANRE (A6H8I0), UBP22_HUMAN (Q9UPT9), 
UBP22_MOUSE (Q5DU02), UBP23_ARATH (Q9FPS4), UBP24_ARATH (Q9FPS3), 
UBP24_HUMAN (Q9UPU5), UBP24_MOUSE (B1AY13), UBP25_ARATH (Q9FPS2), 
UBP25_HUMAN (Q9UHP3), UBP25_MOUSE (P57080), UBP26_ARATH (Q9SCJ9), 
UBP26_HUMAN (Q9BXU7), UBP26_MOUSE (Q99MX1), UBP26_ORYSI (A2XDG4), 
UBP26_ORYSJ (A3AF13), UBP27_ARATH (Q9FPS0), UBP27_HUMAN (A6NNY8), 
UBP27_MOUSE (Q8CEG8), UBP28_CHICK (Q5ZID5), UBP28_HUMAN (Q96RU2), 
UBP28_MOUSE (Q5I043), UBP28_RAT   (D3ZJ96), UBP29_HUMAN (Q9HBJ7), 
UBP29_MOUSE (Q9ES63), UBP2_ARATH  (Q8W4N3), UBP2_BOVIN  (Q2KHV7), 
UBP2_CHICK  (O57429), UBP2_DROME  (Q8IQ27), UBP2_HUMAN  (O75604), 
UBP2_KLULA  (O42726), UBP2_MOUSE  (O88623), UBP2_RAT(Q5U349), 
UBP2_SCHPO  (Q9P3U0), UBP2_YEAST  (Q01476), UBP30_DANRE (A2BGT0), 
UBP30_HUMAN (Q70CQ3), UBP30_MOUSE (Q3UN04), UBP30_RAT   (D3ZPG5), 
UBP30_XENTR (A4QNN3), UBP31_HUMAN (Q70CQ4), UBP32_DROME (M9PD06), 
UBP32_HUMAN (Q8NFA0), UBP32_MOUSE (F8VPZ3), UBP33_BOVIN (A6QNM7), 
UBP33_DANRE (A5PMR2), UBP33_HUMAN (Q8TEY7), UBP33_MOUSE (Q8R5K2), 
UBP33_PONAB (Q5REG5), UBP33_XENTR (Q28CN3), UBP34_HUMAN (Q70CQ2), 
UBP34_MOUSE (Q6ZQ93), UBP35_HUMAN (Q9P2H5), UBP36_DROAN (B3M3M6), 
UBP36_DROER (B3NC86), UBP36_DROGR (B4IXE0), UBP36_DROME (Q9VRP5), 
UBP36_DROMO (B4KXJ5), UBP36_DROPS (Q2LZB1), UBP36_DROSE (B4HUI5), 
UBP36_DROSI (B4QIS3), UBP36_DROVI (B4LG38), UBP36_DROWI (B4MLR8), 
UBP36_DROYA (B4PIW8), UBP36_HUMAN (Q9P275), UBP36_MOUSE (B1AQJ2), 
UBP37_BOVIN (F1N5V1), UBP37_CANLF (E2RK09), UBP37_CHICK (E1C213), 
UBP37_DANRE (E7F6T8), UBP37_HUMAN (Q86T82), UBP37_MOUSE (Q8C0R0), 
UBP37_PIG   (F1SRY5), UBP38_HUMAN (Q8NB14), UBP38_MOUSE (Q8BW70), 
UBP3_ARATH  (O24454), UBP3_HUMAN  (Q9Y6I4), UBP3_MOUSE  (Q91W36), 
UBP3_SCHPO  (O94269), UBP3_YEAST  (Q01477), UBP40_HUMAN (Q9NVE5), 
UBP40_MOUSE (Q8BWR4), UBP42_BOVIN (E1B9W9), UBP42_HUMAN (Q9H9J4), 
UBP42_MOUSE (B2RQC2), UBP42_RAT   (D3ZU96), UBP43_HUMAN (Q70EL4), 
UBP43_MOUSE (Q8BUM9), UBP44_AILME (D2HBJ8), UBP44_DANRE (Q7ZUM8), 
UBP44_HUMAN (Q9H0E7), UBP44_MOUSE (Q8C2S0), UBP44_XENTR (Q0V9G5), 
UBP45_DANRE (E9QG68), UBP45_HUMAN (Q70EL2), UBP45_MOUSE (Q8K387), 
UBP46_CAEEL (P34547), UBP46_DANRE (A5WWB0), UBP46_HUMAN (P62068), 
UBP46_MOUSE (P62069), UBP46_PONAB (Q5RBQ4), UBP46_RAT   (F1M625), 
UBP47_CHICK (E1C1R4), UBP47_HUMAN (Q96K76), UBP47_MOUSE (Q8BY87), 
UBP47_XENLA (Q5U252), UBP47_XENTR (A1A5G2), UBP48_CAEEL (G5ECC7), 
UBP49_HUMAN (Q70CQ1), UBP49_MOUSE (Q6P9L4), UBP4_ARATH  (Q8LAM0), 
UBP4_BOVIN  (A6QR55), UBP4_CANGA  (Q6FQF0), UBP4_EREGS  (Q754R5), 
UBP4_HUMAN  (Q13107), UBP4_KLULA  (Q9HFS7), UBP4_MOUSE  (P35123), 
UBP4_PONAB  (Q5RCD3), UBP4_RAT(B2GUZ1), UBP4_SCHPO  (O60139), 
UBP4_VANPO  (A7TGY3), UBP4_YEAS1  (B3LGK1), UBP4_YEAS7  (A6ZY34), 
UBP4_YEAST  (P32571), UBP50_HUMAN (Q70EL3), UBP50_MACFA (Q4R6D3), 
UBP50_MOUSE (Q6P8X6), UBP51_HUMAN (Q70EK9), UBP51_MOUSE (B1AY15), 
UBP5_ARATH  (O22207), UBP5_HUMAN  (P45974), UBP5_MOUSE  (P56399), 
UBP5_YEAST  (P39944), UBP64_DROME (Q9W4C3), UBP6_ARATH  (Q949Y0), 
UBP6_HUMAN  (P35125), UBP6_SCHPO  (Q92353), UBP6_YEAST  (P43593), 
UBP71_SCHPO (Q9UTT1), UBP72_SCHPO (Q09879), UBP7_ARATH  (Q84WC6), 
UBP7_CAEBR  (Q60MK8), UBP7_CAEEL  (Q7JKC3), UBP7_CHICK  (Q6U7I1), 
UBP7_DROME  (Q9VYQ8), UBP7_HUMAN  (Q93009), UBP7_MOUSE  (Q6A4J8), 
UBP7_RAT(Q4VSI4), UBP7_SCHPO  (Q9P7S5), UBP7_YEAST  (P40453), 
UBP8_ARATH  (Q9C585), UBP8_HUMAN  (P40818), UBP8_MOUSE  (Q80U87), 
UBP8_SCHPO  (Q09738), UBP8_YEAST  (P50102), UBP9_ARATH  (Q93Y01), 
UBP9_YEAST  (P39967), UBPA_DICDI  (P54201), UBPE_DROME  (Q24574), 
UBPL1_MIMIV (Q5UQR3), UBPY_CAEEL  (Q09931), UL17C_HUMAN (C9JPN9), 
UP44A_XENLA (Q6NTR6), UP44B_XENLA (Q5XGZ2), USP9X_HUMAN (Q93008), 
USP9X_MOUSE (P70398), USP9Y_HUMAN (O00507), USP9Y_MOUSE (F8VPU6)
» more

UniProtKB/Swiss-Prot
False negative sequences
29 sequences

U17L1_HUMAN (Q7RTZ2), U17L2_HUMAN (Q6R6M4), U17L3_HUMAN (A6NCW0), 
U17L4_HUMAN (A6NCW7), U17L7_HUMAN (P0C7H9), UBP10_SCHPO (Q9USR2), 
UBP10_YEAST (P53874), UBP11_SCHPO (Q9UUD6), UBP13_DANRE (F1QFS9), 
UBP13_XENTR (F6V6I0), UBP30_DROME (Q9W462), UBP39_HUMAN (Q53GS9), 
UBP39_MOUSE (Q3TIX9), UBP39_PONAB (Q5R761), UBP48_CHICK (Q5ZM45), 
UBP48_HUMAN (Q86UV5), UBP48_MOUSE (Q3V0C5), UBP48_RAT   (Q76LT8), 
UBP54_HUMAN (Q70EL1), UBP54_MOUSE (Q8BL06), UBP54_RAT   (Q6IE24), 
UBP5_PONAB  (Q5R407), UBP9_SCHPO  (Q9P7V9), UBPB_DICDI  (O96612), 
UBPH_CAEEL  (Q8WT44), UBPL2_MIMIV (Q5UPW7), USPL1_DANRE (Q6DRC5), 
USPL1_HUMAN (Q5W0Q7), USPL1_MOUSE (Q3ULM6)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

UBP11_CANLF (Q01988)

		
PDB
[Detailed view]
126 PDB

1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2VHF; 2Y5B; 2Y6E; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3NHE; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5; 4M5W; 4M5X; 4WA6; 5A5B; 5CHT; 5CHV; 5CVM; 5CVN; 5CVO; 5FWI; 5GJQ; 5J7T; 5JTJ; 5JTV; 5K16; 5K1A; 5K1B; 5K1C; 5KYB; 5KYC; 5KYD; 5KYE; 5KYF; 5L8H; 5L8W; 5MPC; 5N9R; 5N9T; 5NGE; 5NGF; 5O71; 5OHK; 5OHN; 5UQV; 5UQX; 5VS6; 5VSB; 5VSK; 5WCH; 5WHC; 5XU8; 6CPM; 6CRN; 6DGF; 6F5H; 6GH9; 6GHA; 6H4H; 6H4I; 6H4J; 6HEH; 6HEI; 6HEJ; 6HEK; 6HEL; 6IIK; 6IIL; 6IIM; 6IIN; 6JLQ; 6M1K; 6ML1; 6T9L; 6VN2; 6VN3; 6VN4; 6VN5; 6VN6; 7AY0; 7AY2; 7CM2; 7QO4; 7QO5; 7R2G; 7TUO; 7W37; 7W38; 7W39; 7W3A; 7W3B; 7W3C; 7W3F; 7W3G; 7W3H; 7W3I; 7W3J; 7W3K; 7W3M; 7W3R; 7W3U; 7XHH; 7XHK; 7YXX; 7YXY; 8BS3; 8BS9; 8D0A; 8D1T; 8D4Z; 8HJE; 8WG5
» more