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| Entry: PS00972 |
General information about the entry
| Entry name [info] | USP_1 |
| Accession [info] | PS00972 |
| Entry type [info] | PATTERN |
| Date [info] |
01-JUN-1994 CREATED;
01-DEC-2013 DATA UPDATE; 13-FEB-2019 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00750 |
| Associated ProRule [info] | PRU10092 |
Name and characterization of the entry
| Description [info] | Ubiquitin specific protease (USP) domain signature 1. |
| Pattern [info] |
G-[LIVMFY]-x(1,3)-[AGCY]-[NASMQG]-x-C-[FYWC]-[LIVMFCA]-[NSTAD]-[SACV]-x- [LIVMSF]-[QF]. |
Numerical results [info]
| Total number of hits | 291 in 291 different sequences |
| Number of true positive hits | 291 in 291 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 29 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 90.94 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 7 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
291 sequences
CREB_ASPCL (A1CIL1 ), CREB_ASPFC (B0Y4P5 ), CREB_ASPFN (B8NSV5 ), CREB_ASPFU (Q4WQI1 ), CREB_ASPNC (A2Q9N1 ), CREB_ASPOR (Q2UUG8 ), CREB_ASPTN (Q0CT11 ), CREB_EMENI (Q96V54 ), CREB_NEOFI (A1CW53 ), CYLD_BOVIN (Q1RMU2 ), CYLD_HUMAN (Q9NQC7 ), CYLD_MOUSE (Q80TQ2 ), CYLD_PONAB (Q5RED8 ), CYLD_RAT (Q66H62 ), FAF_DROME (P55824 ), NOT_DROME (Q9VVR1 ), PUF_DROME (Q9VC56 ), U17L5_HUMAN (A8MUK1 ), U17L6_HUMAN (Q6QN14 ), U17L8_HUMAN (P0C7I0 ), U17LA_HUMAN (C9JJH3 ), U17LB_HUMAN (C9JVI0 ), U17LC_MOUSE (G5E8I7 ), U17LD_HUMAN (C9JLJ4 ), U17LF_HUMAN (C9J2P7 ), U17LH_HUMAN (D6RBQ6 ), U17LI_HUMAN (D6R9N7 ), U17LJ_HUMAN (D6RCP7 ), U17LK_HUMAN (D6RJB6 ), U17LL_HUMAN (D6R901 ), U17LM_HUMAN (D6RA61 ), U17LN_HUMAN (D6RBM5 ), U17LO_HUMAN (Q0WX57 ), U17PA_MOUSE (Q61068 ), U17PB_MOUSE (E9Q9U0 ), U17PD_MOUSE (G5E8G2 ), U17PE_MOUSE (Q7M764 ), UB10A_XENLA (Q2NL57 ), UB10B_XENLA (Q7ZXR7 ), UB12A_XENLA (Q52KZ6 ), UB12B_XENLA (Q5M981 ), UB22A_XENLA (Q6GNI6 ), UB22B_XENLA (Q6DCJ1 ), UBP10_ARATH (Q9ZSB5 ), UBP10_BOVIN (A5PJS6 ), UBP10_CHICK (Q5ZJN4 ), UBP10_HUMAN (Q14694 ), UBP10_MOUSE (P52479 ), UBP10_RAT (Q3KR59 ), UBP10_XENTR (Q6DIJ4 ), UBP11_ARATH (Q9MAQ3 ), UBP11_HUMAN (P51784 ), UBP11_MOUSE (Q99K46 ), UBP11_RAT (Q5D006 ), UBP11_YEAST (P36026 ), UBP12_ARATH (Q9FPT1 ), UBP12_BOVIN (A5D9H7 ), UBP12_DANRE (A4FUN7 ), UBP12_HUMAN (O75317 ), UBP12_MOUSE (Q9D9M2 ), UBP12_SALSA (C0HB46 ), UBP12_SCHPO (O60079 ), UBP12_YEAST (P39538 ), UBP13_ARATH (Q84WU2 ), UBP13_BOVIN (E1BMF7 ), UBP13_CHICK (E1BY77 ), UBP13_HUMAN (Q92995 ), UBP13_MOUSE (Q5BKP2 ), UBP13_YEAST (P38187 ), UBP14_ARATH (Q8L6Y1 ), UBP14_BOVIN (Q0IIF7 ), UBP14_CAEEL (Q17361 ), UBP14_HUMAN (P54578 ), UBP14_MOUSE (Q9JMA1 ), UBP14_PANTR (P60051 ), UBP14_RABIT (P40826 ), UBP14_SCHPO (Q11119 ), UBP14_YEAST (P38237 ), UBP15_ARATH (Q9FPS9 ), UBP15_BOVIN (Q2HJE4 ), UBP15_HUMAN (Q9Y4E8 ), UBP15_MOUSE (Q8R5H1 ), UBP15_RAT (Q9R085 ), UBP15_XENTR (F6Z5C0 ), UBP15_YEAST (P50101 ), UBP16_ARATH (Q9SB51 ), UBP16_BOVIN (Q08DA3 ), UBP16_DANRE (A8HAL1 ), UBP16_EMENI (P0CAQ1 ), UBP16_HUMAN (Q9Y5T5 ), UBP16_MACFA (Q4R6X7 ), UBP16_MOUSE (Q99LG0 ), UBP16_RAT (Q2KJ09 ), UBP16_SCHPO (O74442 ), UBP16_XENLA (Q6PAW2 ), UBP16_XENTR (Q0VA64 ), UBP16_YEAST (Q02863 ), UBP17_ARATH (Q9FKP5 ), UBP18_ARATH (Q67XW5 ), UBP18_HUMAN (Q9UMW8 ), UBP18_MOUSE (Q9WTV6 ), UBP18_PONAB (Q5RE63 ), UBP19_ARATH (Q9SJA1 ), UBP19_HUMAN (O94966 ), UBP19_MOUSE (Q3UJD6 ), UBP19_RAT (Q6J1Y9 ), UBP1_ARATH (Q9FPT5 ), UBP1_BOVIN (Q29RP1 ), UBP1_HUMAN (O94782 ), UBP1_MOUSE (Q8BJQ2 ), UBP1_RAT (Q569C3 ), UBP1_SCHPO (Q9USM5 ), UBP1_YEAST (P25037 ), UBP20_ARATH (Q9FPS7 ), UBP20_BOVIN (A7Z056 ), UBP20_DANRE (A5PN09 ), UBP20_HUMAN (Q9Y2K6 ), UBP20_MOUSE (Q8C6M1 ), UBP20_PONAB (Q5R5Z6 ), UBP20_XENLA (B1WBD7 ), UBP20_XENTR (A0JM59 ), UBP21_ARATH (Q9FIQ1 ), UBP21_BOVIN (Q2KJ72 ), UBP21_HUMAN (Q9UK80 ), UBP21_MOUSE (Q9QZL6 ), UBP21_RAT (B2GUX4 ), UBP21_SCHPO (Q9UTT1 ), UBP22_ARATH (Q9LEW0 ), UBP22_BOVIN (P0C8Z3 ), UBP22_DANRE (A6H8I0 ), UBP22_HUMAN (Q9UPT9 ), UBP22_MOUSE (Q5DU02 ), UBP23_ARATH (Q9FPS4 ), UBP24_ARATH (Q9FPS3 ), UBP24_HUMAN (Q9UPU5 ), UBP24_MOUSE (B1AY13 ), UBP25_ARATH (Q9FPS2 ), UBP25_HUMAN (Q9UHP3 ), UBP25_MOUSE (P57080 ), UBP26_ARATH (Q9SCJ9 ), UBP26_HUMAN (Q9BXU7 ), UBP26_MOUSE (Q99MX1 ), UBP26_ORYSI (A2XDG4 ), UBP26_ORYSJ (A3AF13 ), UBP27_ARATH (Q9FPS0 ), UBP27_HUMAN (A6NNY8 ), UBP27_MOUSE (Q8CEG8 ), UBP28_CHICK (Q5ZID5 ), UBP28_HUMAN (Q96RU2 ), UBP28_MOUSE (Q5I043 ), UBP28_RAT (D3ZJ96 ), UBP29_HUMAN (Q9HBJ7 ), UBP29_MOUSE (Q9ES63 ), UBP2_ARATH (Q8W4N3 ), UBP2_BOVIN (Q2KHV7 ), UBP2_CHICK (O57429 ), UBP2_DROME (Q8IQ27 ), UBP2_HUMAN (O75604 ), UBP2_KLULA (O42726 ), UBP2_MOUSE (O88623 ), UBP2_RAT (Q5U349 ), UBP2_SCHPO (Q9P3U0 ), UBP2_YEAST (Q01476 ), UBP30_DANRE (A2BGT0 ), UBP30_HUMAN (Q70CQ3 ), UBP30_MOUSE (Q3UN04 ), UBP30_RAT (D3ZPG5 ), UBP30_XENTR (A4QNN3 ), UBP31_HUMAN (Q70CQ4 ), UBP32_DROME (M9PD06 ), UBP32_HUMAN (Q8NFA0 ), UBP33_BOVIN (A6QNM7 ), UBP33_DANRE (A5PMR2 ), UBP33_HUMAN (Q8TEY7 ), UBP33_MOUSE (Q8R5K2 ), UBP33_PONAB (Q5REG5 ), UBP33_XENTR (Q28CN3 ), UBP34_HUMAN (Q70CQ2 ), UBP34_MOUSE (Q6ZQ93 ), UBP35_HUMAN (Q9P2H5 ), UBP36_DROAN (B3M3M6 ), UBP36_DROER (B3NC86 ), UBP36_DROGR (B4IXE0 ), UBP36_DROME (Q9VRP5 ), UBP36_DROMO (B4KXJ5 ), UBP36_DROPS (Q2LZB1 ), UBP36_DROSE (B4HUI5 ), UBP36_DROSI (B4QIS3 ), UBP36_DROVI (B4LG38 ), UBP36_DROWI (B4MLR8 ), UBP36_DROYA (B4PIW8 ), UBP36_HUMAN (Q9P275 ), UBP36_MOUSE (B1AQJ2 ), UBP37_BOVIN (F1N5V1 ), UBP37_CANLF (E2RK09 ), UBP37_CHICK (E1C213 ), UBP37_DANRE (E7F6T8 ), UBP37_HUMAN (Q86T82 ), UBP37_MOUSE (Q8C0R0 ), UBP37_PIG (F1SRY5 ), UBP38_HUMAN (Q8NB14 ), UBP38_MOUSE (Q8BW70 ), UBP3_ARATH (O24454 ), UBP3_HUMAN (Q9Y6I4 ), UBP3_MOUSE (Q91W36 ), UBP3_SCHPO (O94269 ), UBP3_YEAST (Q01477 ), UBP40_HUMAN (Q9NVE5 ), UBP40_MOUSE (Q8BWR4 ), UBP41_HUMAN (Q3LFD5 ), UBP42_BOVIN (E1B9W9 ), UBP42_HUMAN (Q9H9J4 ), UBP42_MOUSE (B2RQC2 ), UBP42_RAT (D3ZU96 ), UBP43_HUMAN (Q70EL4 ), UBP43_MOUSE (Q8BUM9 ), UBP44_AILME (D2HBJ8 ), UBP44_DANRE (Q7ZUM8 ), UBP44_HUMAN (Q9H0E7 ), UBP44_MOUSE (Q8C2S0 ), UBP44_XENTR (Q0V9G5 ), UBP45_HUMAN (Q70EL2 ), UBP45_MOUSE (Q8K387 ), UBP46_CAEEL (P34547 ), UBP46_DANRE (A5WWB0 ), UBP46_HUMAN (P62068 ), UBP46_MOUSE (P62069 ), UBP46_PONAB (Q5RBQ4 ), UBP46_RAT (F1M625 ), UBP47_CHICK (E1C1R4 ), UBP47_HUMAN (Q96K76 ), UBP47_MOUSE (Q8BY87 ), UBP47_XENLA (Q5U252 ), UBP47_XENTR (A1A5G2 ), UBP49_HUMAN (Q70CQ1 ), UBP49_MOUSE (Q6P9L4 ), UBP4_ARATH (Q8LAM0 ), UBP4_ASHGO (Q754R5 ), UBP4_BOVIN (A6QR55 ), UBP4_CANGA (Q6FQF0 ), UBP4_HUMAN (Q13107 ), UBP4_KLULA (Q9HFS7 ), UBP4_MOUSE (P35123 ), UBP4_PONAB (Q5RCD3 ), UBP4_RAT (B2GUZ1 ), UBP4_SCHPO (O60139 ), UBP4_VANPO (A7TGY3 ), UBP4_YEAS1 (B3LGK1 ), UBP4_YEAS7 (A6ZY34 ), UBP4_YEAST (P32571 ), UBP50_HUMAN (Q70EL3 ), UBP50_MACFA (Q4R6D3 ), UBP50_MOUSE (Q6P8X6 ), UBP51_HUMAN (Q70EK9 ), UBP51_MOUSE (B1AY15 ), UBP5_ARATH (O22207 ), UBP5_HUMAN (P45974 ), UBP5_MOUSE (P56399 ), UBP5_SCHPO (Q09879 ), UBP5_YEAST (P39944 ), UBP6_ARATH (Q949Y0 ), UBP6_HUMAN (P35125 ), UBP6_SCHPO (Q92353 ), UBP6_YEAST (P43593 ), UBP7_ARATH (Q84WC6 ), UBP7_CAEBR (Q60MK8 ), UBP7_CAEEL (Q7JKC3 ), UBP7_CHICK (Q6U7I1 ), UBP7_DROME (Q9VYQ8 ), UBP7_HUMAN (Q93009 ), UBP7_MOUSE (Q6A4J8 ), UBP7_RAT (Q4VSI4 ), UBP7_SCHPO (Q9P7S5 ), UBP7_YEAST (P40453 ), UBP8_ARATH (Q9C585 ), UBP8_HUMAN (P40818 ), UBP8_MOUSE (Q80U87 ), UBP8_SCHPO (Q09738 ), UBP8_YEAST (P50102 ), UBP9_ARATH (Q93Y01 ), UBP9_YEAST (P39967 ), UBPA_DICDI (P54201 ), UBPE_DROME (Q24574 ), UBPL1_MIMIV (Q5UQR3 ), UBPY_CAEEL (Q09931 ), UL17C_HUMAN (C9JPN9 ), UP44A_XENLA (Q6NTR6 ), UP44B_XENLA (Q5XGZ2 ), USP9X_HUMAN (Q93008 ), USP9X_MOUSE (P70398 ), USP9Y_HUMAN (O00507 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
29 sequences
SNUT2_HUMAN (Q53GS9 ), SNUT2_MOUSE (Q3TIX9 ), SNUT2_PONAB (Q5R761 ), U17L1_HUMAN (Q7RTZ2 ), U17L2_HUMAN (Q6R6M4 ), U17L3_HUMAN (A6NCW0 ), U17L4_HUMAN (A6NCW7 ), U17L7_HUMAN (P0C7H9 ), UBP10_SCHPO (Q9USR2 ), UBP10_YEAST (P53874 ), UBP11_SCHPO (Q9UUD6 ), UBP13_DANRE (F1QFS9 ), UBP13_XENTR (F6V6I0 ), UBP30_DROME (Q9W462 ), UBP48_CHICK (Q5ZM45 ), UBP48_HUMAN (Q86UV5 ), UBP48_MOUSE (Q3V0C5 ), UBP48_RAT (Q76LT8 ), UBP54_HUMAN (Q70EL1 ), UBP54_MOUSE (Q8BL06 ), UBP54_RAT (Q6IE24 ), UBP5_PONAB (Q5R407 ), UBP9_SCHPO (Q9P7V9 ), UBPB_DICDI (O96612 ), UBPH_CAEEL (Q8WT44 ), UBPL2_MIMIV (Q5UPW7 ), USPL1_DANRE (Q6DRC5 ), USPL1_HUMAN (Q5W0Q7 ), USPL1_MOUSE (Q3ULM6 )» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
UBP11_CANLF (Q01988 ) |
| PDB [Detailed view] |
67 PDB
1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2HD5; 2IBI; 2VHF; 2Y5B; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5; 4M5W; 4M5X; 4WA6; 5A5B; 5CHT; 5CHV; 5CVM; 5CVN; 5CVO; 5FWI; 5GJQ; 5J7T; 5JTJ; 5JTV; 5K16; 5K1B; 5K1C; 5KYB; 5KYC; 5KYD; 5KYE; 5KYF; 5L8H; 5L8W; 5N9R; 5N9T; 5NGE; 5NGF; 5O71; 5OHK; 5OHN; 5UQV; 5UQX; 5VS6; 5VSB; 5VSK; 5WCH; 5WHC; 5XU8; 6F5H; 6GH9; 6GHA; 6IIK; 6IIL; 6IIM; 6IIN » more |
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