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PROSITE entry PS00983


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General information about the entry

Entry name [info] LY6_UPAR
Accession [info] PS00983
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00756

Name and characterization of the entry

Description [info] Ly-6 / u-PAR domain signature.
Pattern [info]
[EQR]-C-[LIVMFYAH]-x-C-x(5,8)-C-x(3,8)-[EDNQSTV]-C-{C}-x(5)-C-
x(12,24)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 54 in 38 different sequences
Number of true positive hits 52 in 36 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 72
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 96.30 %
Recall (true positives / (true positives + false negatives)) 41.94 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 3
Site [info] disulfide at position 2
Site [info] disulfide at position 5
Site [info] disulfide at position 7
Site [info] disulfide at position 10
Site [info] disulfide at position 13
Site [info] disulfide at position 15
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
36 sequences

CD59_AOTTR  (P51447), CD59_CALSQ  (P46657), CD59_CHLAE  (Q28216), 
CD59_HUMAN  (P13987), CD59_MACFA  (Q8SQ46), CD59_PAPSP  (Q28785), 
CD59_PIG(O62680), CD59_PONAB  (Q5R510), CD59_RAT(P27274), 
CD59_SHV21  (Q00996), GML_HUMAN   (Q99445), HDBP1_MOUSE (Q9D1N2), 
LY6A_MOUSE  (P05533), LY6C1_MOUSE (P0CW02), LY6C2_MOUSE (P0CW03), 
LY6D_BOVIN  (Q148C3), LY6D_HUMAN  (Q14210), LY6D_MOUSE  (P35459), 
LY6F_MOUSE  (P35460), LY6G_MOUSE  (P35461), LY6I_MOUSE  (Q9WU67), 
LY6S_HUMAN  (P0DTL4), LYPD2_HUMAN (Q6UXB3), LYPD5_HUMAN (Q6UWN5), 
LYPD5_MOUSE (Q9D7Z7), PSCA_MOUSE  (P57096), SLUR1_MOUSE (Q9Z0K7), 
SLUR2_MOUSE (P0DP59), UPAR_AOTTR  (Q9GK77), UPAR_BOVIN  (Q05588), 
UPAR_CHLAE  (Q9GK79), UPAR_HUMAN  (Q03405), UPAR_MACFA  (Q9GK78), 
UPAR_MOUSE  (P35456), UPAR_PANTR  (Q9GK80), UPAR_RAT(P49616)
» more

UniProtKB/Swiss-Prot
False negative sequences
72 sequences

BERO2_DROME (Q9VIH9), BERO_DROME  (Q9VII1), BNCR_DANRE  (P0DPQ9), 
BNCR_ORYLA  (H2LID1), BOUD_DROME  (Q9W3T7), CD177_HUMAN (Q8N6Q3), 
CD59A_MOUSE (O55186), CD59B_MOUSE (P58019), CD59_RABIT  (O77541), 
CD59_SAISC  (P47777), COLD_DROME  (Q9VPR7), CRIM_DROME  (Q9VTM6), 
CROK_DROME  (Q9VKA0), LPD6B_HUMAN (Q8NI32), LPD6B_MOUSE (Q9D7F2), 
LY65B_HUMAN (Q8NDX9), LY65B_MOUSE (Q8K1T4), LY65B_RAT   (Q6MG53), 
LY65C_CANLF (Q9XSV5), LY65C_HUMAN (Q5SRR4), LY65C_MACMU (Q863H0), 
LY65C_MOUSE (Q8K1T5), LY65C_RAT   (Q8CHN2), LY66C_BOVIN (A0JNL5), 
LY66C_HUMAN (O95867), LY66C_MOUSE (Q9Z1Q4), LY66D_HUMAN (O95868), 
LY66D_MOUSE (Q9Z1Q3), LY66D_RAT   (Q6MG58), LY66E_MOUSE (Q8K1T6), 
LY6E_CHICK  (Q90986), LY6E_HUMAN  (Q16553), LY6E_MOUSE  (Q64253), 
LY6H_HUMAN  (O94772), LY6H_MOUSE  (Q9WUC3), LYPD1_HUMAN (Q8N2G4), 
LYPD1_MOUSE (Q8BLC3), LYPD1_RAT   (Q66H42), LYPD2_MOUSE (Q9DD23), 
LYPD3_HUMAN (O95274), LYPD3_MOUSE (Q91YK8), LYPD3_RAT   (O55162), 
LYPD4_BOVIN (Q32LD3), LYPD4_HUMAN (Q6UWN0), LYPD4_MOUSE (Q8BVP6), 
PAT13_MOUSE (D3YWX3), PAT14_MOUSE (Q3UN54), PIP1_PIG(P83106), 
PSCA_HUMAN  (O43653), QVR_DROAN   (B3MFC2), QVR_DROER   (B3NSF6), 
QVR_DROGR   (B4J8Z9), QVR_DROME   (B5A5T4), QVR_DROMO   (B4KR21), 
QVR_DROPE   (B4GAN3), QVR_DROPS   (B5E022), QVR_DROSE   (B4HNI3), 
QVR_DROSI   (B4QBL6), QVR_DROVI   (B4LQ44), QVR_DROWI   (B4MQJ1), 
QVR_DROYA   (B4P641), RTRV_DROME  (Q9VZ21), SACA4_BOVIN (Q32PB3), 
SACA4_HUMAN (Q8TDM5), SACA4_MOUSE (Q80ZQ0), SLUR1_HUMAN (P55000), 
SOLD1_BOVIN (P83107), TWIT_DROME  (Q9VII3), TX101_CRIGR (Q7TQN2), 
TX101_HUMAN (Q9BY14), TX101_MOUSE (Q9JMI7), TX101_RAT   (Q924B5)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

CD59_SHEEP  (P58020)

		
UniProtKB/Swiss-Prot
False positive sequences
2 sequences

IBBB2_HYAOR (C0HM41), IBBC1_HYAOR (C0HLT4)

		
PDB
[Detailed view]
29 PDB

1CDQ; 1CDR; 1CDS; 1ERG; 1ERH; 1YWH; 2FD6; 2I9B; 2J8B; 2OFS; 2UWR; 2UX2; 3BT1; 3BT2; 3LAQ; 3U73; 3U74; 4BIK; 4K24; 4QTI; 5IMT; 5IMY; 6AEX; 6ZD0; 7E17; 7V63; 8B0F; 8B0G; 8B0H
» more