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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00989


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PURL: https://purl.expasy.org/prosite/signature/PS00989

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General information about the entry

Entry name [info] CLAT_ADAPTOR_S
Accession [info] PS00989
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00760

Name and characterization of the entry

Description [info] Clathrin adaptor complexes small chain signature.
Pattern [info] 
[LIVMC]-[LIVM]-Y-[KR]-x(4)-L-Y-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 38 in 38 different sequences
Number of true positive hits 35 in 35 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 23
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.11 %
Recall (true positives / (true positives + false negatives)) 60.34 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 35 sequences 

AP1S1_ARATH (Q8LEZ8), AP1S1_BOVIN (Q1JQ98), AP1S1_HUMAN (P61966), 

AP1S1_MOUSE (P61967), AP1S1_YEAST (P35181), AP1S2_ARATH (O23685), 
AP1S2_BOVIN (Q3ZBS3), AP1S2_HUMAN (P56377), AP1S2_MOUSE (Q9DB50), 
AP1S3_HUMAN (Q96PC3), AP1S3_MOUSE (Q7TN05), AP2S1_BOVIN (Q17QC5), 
AP2S1_HUMAN (P53680), AP2S1_MOUSE (P62743), AP2S1_PONAB (Q5R940), 
AP2S1_RAT   (P62744), AP2S_SCHPO  (Q9Y7L6), AP2S_YEAST  (Q00381), 
AP3S1_BOVIN (Q2YDH6), AP3S1_HUMAN (Q92572), AP3S1_MOUSE (Q9DCR2), 
AP3S2_BOVIN (Q1JQA3), AP3S2_HUMAN (P59780), AP3S2_MOUSE (Q8BSZ2), 
AP3S2_PONAB (Q5RDP9), AP3S_ARATH  (Q8VZ37), AP3S_EREGS  (Q75F71), 
AP3S_SCHPO  (Q09905), AP3S_YEAST  (P47064), APS3_CANAL  (Q59QC5), 
COPZ1_BOVIN (P35604), COPZ1_HUMAN (P61923), COPZ1_MOUSE (P61924), 
COPZ1_PONAB (Q5R5F2), COPZ_CAEEL  (O17901)
» more

UniProtKB/Swiss-Prot
False negative sequences		 23 sequences 

AP1S1_SCHPO (Q9P7N2), AP2S_ASPFU  (Q4WS49), AP2S_EMENI  (Q5BFF8), 

AP2S_GIBZE  (Q4ICG5), AP2S_NEUCR  (Q7SAQ1), AP4S1_BOVIN (Q3ZBB6), 
AP4S1_HUMAN (Q9Y587), AP4S1_MOUSE (Q9WVL1), AP4S_ARATH  (O82201), 
COPZ1_ARATH (Q940S5), COPZ1_ORYSJ (Q9MAX5), COPZ2_ARATH (Q84LG4), 
COPZ2_HUMAN (Q9P299), COPZ2_MOUSE (Q9JHH9), COPZ2_ORYSJ (Q6Z844), 
COPZ3_ARATH (Q8H1F4), COPZ3_ORYSJ (Q5NA06), COPZA_DICDI (Q54HD4), 
COPZB_DICDI (Q54CA7), COPZ_ENCCU  (Q8SRD1), COPZ_SCHPO  (O74891), 
COPZ_YEAST  (P53600), TSTD_DICDI  (C0HLF1)
» more

UniProtKB/Swiss-Prot
False positive sequences		 3 sequences 

SYC_LEPIN   (Q8F525), SYI_BLOFL   (Q7VQL0), TSAD_BUCCC  (Q058D1)


				
	

	

		PDB
[Detailed view]		
		
			66 PDB
			


			pdb_00001w63; pdb_00002hf6; pdb_00002jkr; pdb_00002jkt; pdb_00002vgl; pdb_00002xa7; pdb_00003tjz; pdb_00004hmy; pdb_00004nee; pdb_00004p6z; pdb_00004uqi; pdb_00005a1u; 
			
				pdb_00005a1v; pdb_00005a1w; pdb_00005a1x; pdb_00005a1y; pdb_00005mc7; pdb_00005nzr; pdb_00005nzs; pdb_00005nzt; pdb_00005nzu; pdb_00005nzv; pdb_00006cm9; pdb_00006cri; 
				pdb_00006d83; pdb_00006d84; pdb_00006dff; pdb_00006owo; pdb_00006owt; pdb_00006oxl; pdb_00006qh5; pdb_00006qh6; pdb_00006qh7; pdb_00006uri; pdb_00006yae; pdb_00006yaf; 
				pdb_00006yah; pdb_00007og1; pdb_00007oho; pdb_00007p3x; pdb_00007p3y; pdb_00007p3z; pdb_00007r4h; pdb_00007rw8; pdb_00007rw9; pdb_00007rwa; pdb_00007rwb; pdb_00007rwc; 
				pdb_00007ux3; pdb_00007z5c; pdb_00008d4c; pdb_00008d4d; pdb_00008d4e; pdb_00008d4f; pdb_00008d4g; pdb_00008d9r; pdb_00008d9s; pdb_00008d9t; pdb_00008d9u; pdb_00008d9v; 
				pdb_00008d9w; pdb_00008t1o; pdb_00009c58; pdb_00009c59; pdb_00009c5b; pdb_00009c5c
			
			

			» more