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PROSITE entry PS01098


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General information about the entry

Entry name [info] LIPASE_GDSL_SER
Accession [info] PS01098
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00842

Name and characterization of the entry

Description [info] Lipolytic enzymes "G-D-S-L" family, serine active site.
Pattern [info]
[LIVMFYAG](4)-G-D-S-[LIVM]-x(1,2)-[TAG]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 54 in 48 different sequences
Number of true positive hits 49 in 43 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 124
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 90.74 %
Recall (true positives / (true positives + false negatives)) 28.32 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
43 sequences

APG_ARATH   (P40602), APG_BRANA   (P40603), ESTA_PSEAE  (O33407), 
ESTA_PSEPU  (Q6B6R8), ESTE_VIBMI  (Q07792), ESTP_PSEPK  (Q88QS0), 
EXL1_ARATH  (Q94CH8), EXL2_ARATH  (Q94CH7), EXL3_ARATH  (Q94CH6), 
EXL4_ARATH  (Q0WUV7), EXL5_ARATH  (Q94CH5), EXL6_ARATH  (Q93X94), 
GCAT_AERHY  (P10480), GDL24_ARATH (Q9C653), GDL25_ARATH (Q3ECM4), 
GDL26_ARATH (F4IBF0), GDL27_ARATH (P0DI15), GDL28_ARATH (Q9FVV1), 
GDL30_ARATH (Q9C9V0), GDL4_ARATH  (P0DKJ6), GDL52_ARATH (Q9LH73), 
GDL55_ARATH (Q3EAQ9), GDL56_ARATH (Q9FYD3), GDL5_ARATH  (Q9ZUE4), 
GDL72_ARATH (Q9FFN0), GDL73_ARATH (Q9LZC5), GDL87_ARATH (Q9FIA1), 
GDL89_ARATH (Q9FMK6), GLIP1_ARATH (Q9FLN0), GLIP2_ARATH (Q9SYF0), 
GLIP3_ARATH (Q9SYF5), GRIP4_ARATH (Q9LJP1), HLT_VIBPA   (Q99289), 
LIP1_PHOLU  (P40601), PLB1_CAVPO  (O70320), PLB1_HUMAN  (Q6P1J6), 
PLB1_MONDO  (Q06HQ7), PLB1_MOUSE  (Q3TTY0), PLB1_RABIT  (Q05017), 
PLB1_RAT(O54728), TESA_ECOL6  (P0ADA2), TESA_ECOLI  (P0ADA1), 
YTRP_PSEPU  (P40604)
» more

UniProtKB/Swiss-Prot
False negative sequences
124 sequences

AAE_RAUSE   (Q3MKY2), AOAH_HUMAN  (P28039), AOAH_MOUSE  (O35298), 
AOAH_RABIT  (O18823), APG2_ARATH  (Q9LU14), AXE2_GEOSE  (Q09LX1), 
CPR49_ARATH (Q9SRM5), ESM1_ARATH  (Q9LJG3), EST_HEVBR   (Q7Y1X1), 
EST_PSEAE   (Q9HZY8), FUCO3_ARATH (Q9FXE5), GDL10_ARATH (Q9SHP6), 
GDL11_ARATH (Q3E7I6), GDL12_ARATH (Q9FPE4), GDL13_ARATH (Q38894), 
GDL14_ARATH (Q9C7N5), GDL15_ARATH (Q9C7N4), GDL16_ARATH (Q9C857), 
GDL17_ARATH (Q8L5Z1), GDL18_ARATH (Q1H583), GDL19_ARATH (Q8W4H8), 
GDL1_ARATH  (Q9LMJ3), GDL1_CARPA  (P86276), GDL20_ARATH (Q9C5N8), 
GDL21_ARATH (Q7XA74), GDL22_ARATH (Q3ECP6), GDL23_ARATH (Q9C648), 
GDL29_ARATH (Q9SF78), GDL2_ARATH  (O80522), GDL31_ARATH (Q9CA68), 
GDL32_ARATH (Q9SIF5), GDL33_ARATH (Q9SIF3), GDL34_ARATH (Q9SJB4), 
GDL35_ARATH (O65921), GDL36_ARATH (O64468), GDL37_ARATH (O64469), 
GDL38_ARATH (O80470), GDL39_ARATH (Q9SJA9), GDL3_ARATH  (Q9LMS5), 
GDL40_ARATH (Q9ZQI3), GDL41_ARATH (O22918), GDL42_ARATH (O22927), 
GDL43_ARATH (Q9SIQ3), GDL44_ARATH (Q9SIQ2), GDL45_ARATH (Q8RWJ4), 
GDL46_ARATH (O80443), GDL47_ARATH (Q9SIZ6), GDL48_ARATH (Q67ZI9), 
GDL49_ARATH (Q9MAA1), GDL50_ARATH (Q9SF94), GDL51_ARATH (Q9LJP2), 
GDL53_ARATH (Q9LIN2), GDL54_ARATH (Q9LII9), GDL57_ARATH (Q9STM6), 
GDL58_ARATH (Q9M2R9), GDL59_ARATH (Q0WPI9), GDL60_ARATH (Q6NLP7), 
GDL61_ARATH (Q9M153), GDL62_ARATH (Q680C0), GDL63_ARATH (O23469), 
GDL64_ARATH (O23470), GDL65_ARATH (Q93YW8), GDL66_ARATH (Q8VY93), 
GDL67_ARATH (Q9SVU5), GDL68_ARATH (Q9SZW7), GDL69_ARATH (Q9LZS9), 
GDL6_ARATH  (Q9FXJ1), GDL70_ARATH (Q9LZS8), GDL71_ARATH (Q9LZS7), 
GDL74_ARATH (Q9LZB2), GDL75_ARATH (Q9FNP2), GDL76_ARATH (Q9LY84), 
GDL77_ARATH (Q5PNZ0), GDL78_ARATH (Q9FFC6), GDL79_ARATH (Q8LB81), 
GDL7_ARATH  (Q9FXJ2), GDL80_ARATH (Q9FHQ1), GDL81_ARATH (Q9FJ25), 
GDL82_ARATH (Q9FK75), GDL83_ARATH (Q9FJ45), GDL84_ARATH (Q6NMR9), 
GDL85_ARATH (Q9FJ41), GDL86_ARATH (Q9FJ40), GDL88_ARATH (Q9FM04), 
GDL8_ARATH  (Q8RXT9), GDL90_ARATH (Q9FHW9), GDL91_ARATH (P0C8Z7), 
GDL9_ARATH  (Q94F40), GDSLL_MYCTU (O53423), GDSL_MYCTU  (O33363), 
GLIP5_ARATH (Q9SSA7), GLIP6_ARATH (Q9C996), GLIP7_ARATH (Q8LFJ9), 
IAH1_BOVIN  (Q3SZ16), IAH1_DANRE  (Q503L4), IAH1_HUMAN  (Q2TAA2), 
IAH1_MOUSE  (Q9DB29), IAH1_RAT(Q711G3), IAH1_SCHPO  (O74648), 
IAH1_YEAST  (P41734), LIP1_STRCO  (Q9S2A5), LIP2_STRCO  (Q93J06), 
LIP4_ARATH  (Q9FXB6), LIPC_BACLD  (Q65NA4), LIPC_BACSU  (P42969), 
LIP_STRRM   (Q93MW7), LTL1_ARATH  (Q9M8Y5), PA1B2_BOVIN (P68401), 
PA1B2_CHICK (Q5ZMS2), PA1B2_DROME (Q9VXP4), PA1B2_HUMAN (P68402), 
PA1B2_MOUSE (Q61206), PA1B2_PONAB (Q5R4G2), PA1B2_RAT   (O35264), 
PA1B3_BOVIN (Q29460), PA1B3_HUMAN (Q15102), PA1B3_MOUSE (Q61205), 
PA1B3_PONAB (Q5R6X1), PA1B3_RAT   (O35263), RHA1_ASPAC  (Q00017), 
RHGT1_BACSU (O31523), RHGT2_BACSU (O31528), SSEJ_SALTY  (Q9FD10), 
YXIM_BACSU  (P42304)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

AAE_RAUVE   (P86830), GDSLH_POPEU (P84985), SFAH_HELAN  (P81098)

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

CYF_SYNR3   (A5GRU7), NAGS_AJECN  (A6RBX7), RGTB_RHIJ3  (Q1MJ97), 
SMG8_MOUSE  (Q8VE18), Y479_CLOAB  (Q97LS5)
» more

PDB
[Detailed view]
12 PDB

1IVN; 1J00; 1JRL; 1U8U; 1V2G; 3KVN; 5TIC; 5TID; 5TIE; 5TIF; 6LFB; 6LFC