PROSITE entry PS01121
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General information about the entry
| Entry name [info] | CASPASE_HIS |
| Accession [info] | PS01121 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1995 CREATED;
01-DEC-2004 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00864 |
Name and characterization of the entry
| Description [info] | Caspase family histidine active site. |
| Pattern [info] |
H-x(2,4)-[SC]-x(2)-{A}-x-[LIVMF](2)-[ST]-H-G.
|
Numerical results [info]
| Total number of hits | 68 in 68 different sequences |
| Number of true positive hits | 58 in 58 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 10 in 10 different sequences |
| Number of false negative sequences | 4 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 85.29 % |
| Recall (true positives / (true positives + false negatives)) | 93.55 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 9 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
58 sequences
CAS1A_XENLA (P55865 ), CAS1B_XENLA (P55867 ), CASP1_CANLF (Q9MZV7 ), CASP1_DROME (O02002 ), CASP1_FELCA (Q9MZV6 ), CASP1_HORSE (Q9TV13 ), CASP1_HUMAN (P29466 ), CASP1_MOUSE (P29452 ), CASP1_PIG (Q9N2I1 ), CASP1_RAT (P43527 ), CASP1_SPOFR (P89116 ), CASP2_CHICK (Q98943 ), CASP2_HUMAN (P42575 ), CASP2_MOUSE (P29594 ), CASP2_RAT (P55215 ), CASP3_BOVIN (Q08DY9 ), CASP3_CANLF (Q8MKI5 ), CASP3_FELCA (Q8MJU1 ), CASP3_HUMAN (P42574 ), CASP3_MACFA (Q2PFV2 ), CASP3_MESAU (Q60431 ), CASP3_MOUSE (P70677 ), CASP3_PANTR (Q5IS54 ), CASP3_PIG (Q95ND5 ), CASP3_RABIT (Q8MJC3 ), CASP3_RAT (P55213 ), CASP3_SAIBB (Q5IS99 ), CASP3_XENLA (P55866 ), CASP4_BOVIN (Q5E9C1 ), CASP4_HUMAN (P49662 ), CASP4_MOUSE (P70343 ), CASP5_HUMAN (P51878 ), CASP6_BOVIN (Q3T0P5 ), CASP6_HUMAN (P55212 ), CASP6_MOUSE (O08738 ), CASP6_RAT (O35397 ), CASP7_CHICK (F1NV61 ), CASP7_HUMAN (P55210 ), CASP7_MESAU (P55214 ), CASP7_MOUSE (P97864 ), CASP8_HUMAN (Q14790 ), CASP8_MOUSE (O89110 ), CASP8_RAT (Q9JHX4 ), CASP9_HUMAN (P55211 ), CASP9_MOUSE (Q8C3Q9 ), CASPA_DANRE (Q9I9L7 ), CASPA_HUMAN (Q92851 ), CASPB_DANRE (Q504J1 ), CASPC_CANLF (Q075B4 ), CASPC_MACMU (Q153Z0 ), CASPC_MOUSE (O08736 ), CASPC_RAT (Q920D5 ), CASPD_BOVIN (O75601 ), CED3_CAEEL (P42573 ), CED3_CAERE (P45436 ), CSP1_CAEEL (G5EBM1 ), CSP2_CAEEL (Q9TZP5 ), DRICE_DROME (O01382 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
4 sequences
CASP8_DROME (Q8IRY7 ), CASPE_HUMAN (P31944 ), CASPE_MOUSE (O89094 ), DRONC_DROME (Q9XYF4 )» more |
| UniProtKB/Swiss-Prot False positive sequences |
10 sequences
ACCC_ALLVD (O52058 ), CESAA_ARATH (Q9SKJ5 ), FENR_STAS1 (Q49ZU9 ), ICH_DROME (Q9VHJ6 ), PARP2_HUMAN (Q9UGN5 ), PARP2_MOUSE (O88554 ), RN133_MACFA (Q95K04 ), RPOD_BUCAP (P32001 ), SUGPH_MYCTU (Q6MWZ7 ), TDRD5_DANRE (Q1L981 )» more |
| PDB [Detailed view] |
243 PDB
1BMQ; 1CP3; 1F1J; 1F9E; 1GFW; 1GQF; 1I3O; 1I4E; 1I4O; 1I51; 1IBC; 1ICE; 1JXQ; 1K86; 1K88; 1KMC; 1M72; 1NME; 1NMQ; 1NMS; 1NW9; 1PAU; 1PYO; 1QDU; 1QTN; 1QX3; 1RE1; 1RHJ; 1RHK; 1RHM; 1RHQ; 1RHR; 1RHU; 1RWK; 1RWM; 1RWN; 1RWO; 1RWP; 1RWV; 1RWW; 1RWX; 1SC1; 1SC3; 1SC4; 1SHJ; 1SHL; 2AR9; 2C1E; 2C2K; 2C2M; 2C2O; 2C2Z; 2CDR; 2CJX; 2CJY; 2CNK; 2CNL; 2CNN; 2CNO; 2DKO; 2FQQ; 2FUN; 2H48; 2H4W; 2H4Y; 2H51; 2H54; 2H5I; 2H5J; 2H65; 2HBQ; 2HBR; 2HBY; 2HBZ; 2J30; 2J31; 2J32; 2J33; 2K7Z; 2P2C; 2QL5; 2QL7; 2QL9; 2QLB; 2QLF; 2QLJ; 2WDP; 2XYG; 2XYH; 2XYP; 2XZD; 2XZT; 2Y0B; 2Y1L; 3D6F; 3D6H; 3D6M; 3DEH; 3DEI; 3DEJ; 3DEK; 3E4C; 3EDQ; 3EDR; 3GJQ; 3GJR; 3GJS; 3GJT; 3H0E; 3H11; 3H1P; 3IBC; 3IBF; 3ITN; 3K7E; 3KJF; 3KJN; 3KJQ; 3NKF; 3NR2; 3NS7; 3OD5; 3P45; 3P4U; 3PCX; 3PD0; 3PD1; 3QNW; 3R5J; 3R5K; 3R6G; 3R6L; 3R7B; 3R7N; 3R7S; 3RJM; 3S70; 3S8E; 3SIP; 3SIR; 3V3K; 3V6L; 3V6M; 4DCJ; 4DCO; 4DCP; 4EHA; 4EHD; 4EHF; 4EHH; 4EHK; 4EHL; 4EHN; 4EJF; 4FDL; 4FEA; 4FXO; 4HQ0; 4HQR; 4HVA; 4JB8; 4JJ7; 4JJ8; 4JJE; 4JQY; 4JQZ; 4JR0; 4JR1; 4JR2; 4LSZ; 4M9R; 4N5D; 4N6G; 4N7J; 4N7M; 4NBK; 4NBL; 4NBN; 4PRY; 4PRZ; 4PS0; 4PS1; 4QTX; 4QTY; 4QU0; 4QU5; 4QU8; 4QU9; 4QUA; 4QUB; 4QUD; 4QUE; 4QUG; 4QUH; 4QUI; 4QUJ; 4QUL; 4ZVO; 4ZVP; 4ZVQ; 4ZVR; 4ZVS; 4ZVT; 4ZVU; 5I9B; 5I9T; 5IAB; 5IAE; 5IAG; 5IAJ; 5IAK; 5IAN; 5IAR; 5IAS; 5IBC; 5IBP; 5IBR; 5IC4; 5IC6; 5K20; 5MMV; 5MTK; 5V6U; 5V6Z; 6BZ9; 6DEU; 6DEV; 6F6R; 6KMT; 6KMU; 6KMV; 6KMZ; 6KN0; 6KN1; 6NRY; 6NS7; 6PX9; 6PZP; 6VIE; 7WZS; 7XN4; 7XN5; 7XN6 » more |