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PROSITE entry PS01138


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01138
Entry name [info] SCORP_SHORT_TOXIN
Accession [info] PS01138
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-MAY-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00875

Name and characterization of the entry

Description [info] Scorpion short toxins signature.
Pattern [info] 
C-x(3)-C-x(6,9)-[GAS]-K-C-[IMQT]-x(3)-C-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 132 in 132 different sequences
Number of true positive hits 131 in 131 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 63
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.24 %
Recall (true positives / (true positives + false negatives)) 67.53 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 10
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 131 sequences 

DF113_ARATH (Q2V342), KA101_CENNO (O46028), KA102_CENNO (P58504), 

KA104_CENTE (C0HJW2), KA121_TITSE (P59936), KA122_TITTR (P0C168), 
KA123_TITCO (P0C185), KA124_TITST (P0C8L1), KA125_LYCMC (P0CH12), 
KA127_LYCMC (P0CI48), KA12O_SCOPC (P0DQN5), KA151_ANDAU (P60233), 
KA152_OLIMR (Q8I0L5), KA153_ANDMA (P60208), KA154_ANDAU (Q867F4), 
KA155_ANDAU (Q86SD8), KA156_TITDI (P84777), KA157_ANDAM (Q5K0E0), 
KA158_OLIMR (Q86BX0), KA159_LYCMC (D9U2A8), KA15S_CHATC (P0DJO5), 
KA161_HOTTA (P0C173), KA162_OLIMR (Q9NBG9), KA163_OLIMR (Q8MQL0), 
KA164_MESEU (D3JXM1), KA165_LEIHE (P45660), KA166_BUTIS (B8XH42), 
KA167_MESGB (B3EWY1), KA168_BUTPA (P0DL45), KA169_BUTPA (P0DL46), 
KA191_OLIMR (P83407), KA192_BUTOC (C0HJQ2), KA231_VAEMS (P0DJ31), 
KA232_VAEMS (P0DJ32), KA233_SCOTI (P0DP36), KA23N_VAEMS (P0DW84), 
KA261_OLIMR (A7KJJ7), KA263_MESGB (A0A059UI21), KA26U_OLIMR (P0DL65), 
KA271_BUTIS (B8XH44), KAX11_LEIHE (P13487), KAX12_LEIHE (P45628), 
KAX13_HOTTA (P24663), KAX14_CENLM (P0C167), KAX15_OLIMR (Q9NII6), 
KAX16_OLIMR (Q9NII5), KAX19_CENLM (P59848), KAX1A_PARTR (P83112), 
KAX1B_CENNO (P0C182), KAX1C_LEIHE (P59943), KAX1D_LEIHE (P59944), 
KAX1F_OLIMR (H2ER23), KAX1G_MESEU (C0HJQ8), KAX1H_MESEU (C0HJQ7), 
KAX1I_RHOJU (C0HJS9), KAX1X_OLIMR (H2ER22), KAX21_CENNO (P08815), 
KAX22_CENMA (P40755), KAX23_CENLI (P45629), KAX24_CENNO (Q9TXD1), 
KAX25_CENLM (P59847), KAX27_CENLI (P45630), KAX28_CENEL (P0C161), 
KAX29_CENEL (P0C162), KAX2A_CENEL (P0C163), KAX2B_CENEL (P0C164), 
KAX2C_CENEL (P0C165), KAX2D_CENSU (P85529), KAX2E_HETGR (P0DL43), 
KAX2F_CENTE (C0HJW1), KAX2H_CENTE (C0HJW5), KAX2I_CENLI (P0DL70), 
KAX2J_RHOJU (C0HJT0), KAX2K_CENTE (P0DUI4), KAX31_ANDMA (P24662), 
KAX32_LEIHE (P46111), KAX33_LEIHE (P46112), KAX34_LEIHE (P46110), 
KAX35_ANDAU (P45696), KAX36_OLIMR (Q9NII7), KAX37_ORTSC (P55896), 
KAX38_HOTTS (P59886), KAX39_BUTOC (P59290), KAX3A_BUTIS (P0C908), 
KAX3B_ODODO (P0C909), KAX3C_ANDAM (P0C8R1), KAX3D_MESEU (P86396), 
KAX3G_MESGB (K7XFK5), KAX3H_BUTPA (P0DL44), KAX3I_MESEU (C0HJQ4), 
KAX3J_MESEU (C0HJQ6), KAX41_TITSE (P46114), KAX42_TITSE (P56219), 
KAX43_TITDI (P59925), KAX44_TITOB (P60210), KAX45_TITCO (Q5G8B6), 
KAX47_TITST (P0DPT4), KAX51_LEIHE (P16341), KAX52_ANDMA (P31719), 
KAX53_OLIMR (Q9TVX3), KAX54_HOTTA (P59869), KAX55_HOTTA (P59870), 
KAX61_PANIM (Q10726), KAX62_SCOPA (P80719), KAX63_HETSP (P59867), 
KAX64_PANIM (P58498), KAX66_OPICA (Q6XLL9), KAX67_OPICA (Q6XLL8), 
KAX68_OPICA (Q6XLL7), KAX69_OPICA (Q6XLL6), KAX6A_OPICA (Q6XLL5), 
KAX6B_OPIMA (P0C194), KAX6C_ANUPH (P0C166), KAX6D_HETSP (P84094), 
KAX6E_HOFGE (P84864), KAX6F_HEMLE (P85528), KAX6H_OPICY (P86116), 
KAX6L_UROYA (P0DL37), KAX6V_HETLA (C0HJN0), KAX71_PANIM (P55927), 
KAX72_PANIM (P55928), KAX_BUTIS   (B8XH38), KAX_ISOMC   (P0CJ24), 
KEX12_TITSE (P0C175), KEX1S_TITSE (P0C176), KTX22_TITSE (A0A218QX22), 
KTX23_TITSE (A0A218QXG2), KTX24_TITSE (A0A218QWZ8), KTX25_TITSE (A0A218QWZ7), 
KTXA_LYCMC  (D9U2B0), TXN1A_PARTR (P0DUJ3)
» more

UniProtKB/Swiss-Prot
False negative sequences		 63 sequences 

KA111_PARVI (P60164), KA112_PARVI (P60165), KA113_PARGR (Q6WGI9), 

KA11L_LYCMC (A9QLM3), KA126_LYCMC (P0CI47), KA131_TITOB (P83243), 
KA132_ORTSC (P83244), KA133_TITPA (P84630), KA141_OLIMR (Q967F9), 
KA142_OLIMR (Q95NK7), KA143_OLIMR (Q9BJX2), KA144_OLIMR (Q9BKB4), 
KA14_OLIMR  (A0ASK0), KA171_OLIMR (Q95NJ8), KA172_LYCMC (P0CI46), 
KA181_TITOB (P60211), KA182_TITDI (P0C1X5), KA183_TITDI (P0C1X6), 
KA201_TITTR (P0C183), KA20_TITSE  (P86271), KA211_TITSE (P86270), 
KA221_OLIMR (Q8MUB1), KA23H_HOTJU (F1CIY9), KA23I_HOTJU (F1CJ67), 
KA23J_HOTJU (F1CJ80), KA23K_BUTIS (B8XH30), KA23L_BUTIS (B8XH45), 
KA23M_BUTIS (B8XH47), KA262_LYCMC (D9U2B2), KA272_LYCMC (P0CI83), 
KA273_LYCMC (P0CI84), KA274_MESGB (A0A059UEE4), KA281_ISOMC (R4GUQ3), 
KA292_LYCMC (R4GUQ1), KA301_SCOR  (P0DL33), KA302_SCOJE (P0DL34), 
KA303_SCOJE (P0DL35), KAX1E_OLIMR (H2ETQ6), KAX2G_CENTE (C0HJW6), 
KAX65_PANIM (P58490), KAX81_ANDMA (P56215), KAX82_OLIMR (Q9U8D2), 
KAX83_LEIHE (P80670), KAX84_LEIHE (P80671), KAX85_ODODO (P0CC12), 
KAX86_MESEU (P86400), KAX91_OLIMR (Q9NJP7), KAX92_OLIMR (Q9U8D1), 
KAX93_AEGNI (C0HMB3), KAX93_LEIHE (P80669), KAX94_HOTTA (P60209), 
KAX95_BUTOC (P84744), KAX96_HOTJU (P83405), KAX97_HOTJU (P83406), 
KAX9A_MESEU (P86398), KAX9B_MESGB (B3EWX9), KAX9J_HOTTS (P15230), 
KAXUB_TITST (P0C8X6), KEX11_TITSE (P0C174), KGX21_MESEU (Q9BKB7), 
KGX22_OLIMR (P59938), KTXD_LYCMC  (P0CI85), SCS1_OLIMR  (Q95P89)
» more

UniProtKB/Swiss-Prot
False positive sequences		 1 sequence 

KAX46_TITST (P0CB56)


				
	

	

		PDB
[Detailed view]		
		
			71 PDB
			


			1AGT; 1BIG; 1BKT; 1C49; 1C55; 1C56; 1HLY; 1HP2; 1KTX; 1LIR; 1M2S; 1MTX; 
			
				1N8M; 1PJV; 1PNH; 1Q2K; 1QUZ; 1R1G; 1SCO; 1SCY; 1SXM; 1TSK; 1TXM; 1WMT; 
				1WPD; 1WT7; 1WZ5; 1XSW; 1Y2P; 2A9H; 2AXK; 2BMT; 2CK4; 2CK5; 2CRD; 2K4U; 
				2K9O; 2KTX; 2KY3; 2LU9; 2ME7; 2MEL; 2MEN; 2MEO; 2MLA; 2MLD; 2PTA; 2RTZ; 
				2UVS; 3E8Y; 3ODV; 4JTA; 4JTC; 6ATL; 6ATM; 6ATN; 6AVC; 6AVD; 6D3T; 6D8H; 
				6D8Q; 6D8R; 6D8S; 6D8T; 6D8Y; 6D93; 6D9O; 6D9P; 6GGZ; 6MZT; 6SAB
			
			

			» more