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PROSITE entry PS01159


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PURL: https://purl.expasy.org/prosite/signature/PS01159

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General information about the entry

Entry name [info] WW_DOMAIN_1
Accession [info] PS01159
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50020

Name and characterization of the entry

Description [info] WW/rsp5/WWP domain signature.
Pattern [info] 
W-x(9,11)-[VFY]-[FYW]-x(6,7)-[GSTNE]-[GSTQCR]-[FYW]-{R}-{SA}-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 346 in 240 different sequences
Number of true positive hits 287 in 181 different sequences
Number of 'unknown' hits 0
Number of false positive hits 59 in 59 different sequences
Number of false negative sequences 62
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 82.95 %
Recall (true positives / (true positives + false negatives)) 82.23 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 181 sequences 

APBB1_HUMAN (O00213), APBB1_MOUSE (Q9QXJ1), APBB1_RAT   (P46933), 

APBB2_HUMAN (Q92870), APBB2_MOUSE (Q9DBR4), APBB3_HUMAN (O95704), 
APBB3_MOUSE (Q8R1C9), APBB3_RAT   (O35827), BAG3_HUMAN  (O95817), 
BAG3_MOUSE  (Q9JLV1), CMTR1_AILME (D2HRF1), CMTR1_BOVIN (A2VE39), 
CMTR1_DANRE (Q803R5), CMTR1_HUMAN (Q8N1G2), CMTR1_PONAB (Q5R981), 
CMTR1_XENLA (Q6GQ76), DB10_NICSY  (P46942), DMD_CAEEL   (Q9TW65), 
DMD_CANLF   (O97592), DMD_CHICK   (P11533), DMD_HUMAN   (P11532), 
DMD_MOUSE   (P11531), DMD_PIG (Q5GN48), DMD_RAT (P11530), 
DOD_DROME   (P54353), DRE4_SCHPO  (Q09685), DRP2_HUMAN  (Q13474), 
DRP2_MOUSE  (Q05AA6), DRP2_RAT(Q9EPA0), DWWA_DICDI  (Q54T86), 
ESS1_YEAST  (P22696), FNBP4_HUMAN (Q8N3X1), FNBP4_MOUSE (Q6ZQ03), 
GAS7_HUMAN  (O60861), GAS7_MOUSE  (Q60780), GAS7_RAT(O55148), 
HECW1_CAEEL (Q09291), HECW1_HUMAN (Q76N89), HECW1_MOUSE (Q8K4P8), 
HECW2_HUMAN (Q9P2P5), HECW2_MOUSE (Q6I6G8), IQGA1_HUMAN (P46940), 
IQGA1_MOUSE (Q9JKF1), IQGA2_HUMAN (Q13576), IQGA2_MOUSE (Q3UQ44), 
ITCH_HUMAN  (Q96J02), ITCH_MOUSE  (Q8C863), KIBRA_DROAN (B3LWS4), 
KIBRA_DROER (B3P3M8), KIBRA_DROME (Q9VFG8), KIBRA_DROMO (B4K6I9), 
KIBRA_DROSE (B4HEJ6), KIBRA_DROVI (B4M5X4), KIBRA_DROWI (B4NAD3), 
KIBRA_DROYA (B4PSQ2), KIBRA_HUMAN (Q8IX03), KIBRA_MOUSE (Q5SXA9), 
KIBRA_XENTR (A4IIJ3), MAGI1_HUMAN (Q96QZ7), MAGI1_MOUSE (Q6RHR9), 
MAGI1_RAT   (Q4L1J4), MAGI2_HUMAN (Q86UL8), MAGI2_MOUSE (Q9WVQ1), 
MAGI2_RAT   (O88382), MAGI3_CHICK (Q5F488), MAGI3_HUMAN (Q5TCQ9), 
MAGI3_MOUSE (Q9EQJ9), MAGI3_RAT   (Q9JK71), MAGI3_XENTR (A1A5G4), 
NED4L_HUMAN (Q96PU5), NED4L_MOUSE (Q8CFI0), NED4L_PONAB (Q5RBF2), 
NEDD4_DROME (Q9VVI3), NEDD4_HUMAN (P46934), NEDD4_MOUSE (P46935), 
NEDD4_RAT   (Q62940), PIN1_BOVIN  (Q5BIN5), PIN1_HUMAN  (Q13526), 
PIN1_MACFA  (Q4R383), PIN1_MOUSE  (Q9QUR7), PINL_HUMAN  (O15428), 
PKHA5_HUMAN (Q9HAU0), PKHA7_DANRE (B6RSP1), PKHA7_HUMAN (Q6IQ23), 
PKHA7_MOUSE (Q3UIL6), PR40A_HUMAN (O75400), PR40A_MOUSE (Q9R1C7), 
PR40B_ARATH (F4JCC1), PR40B_HUMAN (Q6NWY9), PR40B_MOUSE (Q80W14), 
PR40C_ARATH (Q9LT25), PRP40_YEAST (P33203), PUB1_SCHPO  (Q92462), 
PUB2_SCHPO  (Q9UTG2), PUB3_SCHPO  (O14326), RH14_ARATH  (Q8H136), 
RH40_ARATH  (Q9SQV1), RH40_ORYSJ  (Q5JKF2), RH46_ARATH  (Q9LYJ9), 
RSP5_ASPCL  (A1CQG2), RSP5_ASPFC  (B0XQ72), RSP5_ASPFN  (B8N7E5), 
RSP5_ASPFU  (Q4WTF3), RSP5_ASPNC  (A2QQ28), RSP5_ASPOR  (Q2UBP1), 
RSP5_ASPTN  (Q0CCL1), RSP5_CHATD  (G0S9J5), RSP5_EMENI  (Q5BDP1), 
RSP5_NEOFI  (A1D3C5), RSP5_YEAST  (P39940), SAC9_ARATH  (Q7XZU0), 
SEC24_MYCMD (Q4P9K4), SET2_ASPOR  (Q2UTN6), SET2_CANAL  (Q59XV0), 
SET2_CHAGB  (Q2H988), SET2_COCIM  (Q1DU03), SET2_DROME  (Q9VYD1), 
SET2_EMENI  (Q5ASA5), SET2_GIBZE  (Q4IB50), SET2_NEUCR  (Q7RZU4), 
SETD2_HUMAN (Q9BYW2), SETD2_MOUSE (E9Q5F9), SMUF1_DROME (Q9V853), 
SMUF1_HUMAN (Q9HCE7), SMUF1_MOUSE (Q9CUN6), SMUF1_XENLA (Q9PUN2), 
SMUF2_DANRE (A9JRZ0), SMUF2_HUMAN (Q9HAU4), SMUF2_MOUSE (A2A5Z6), 
SMUF2_XENLA (Q2TAS2), SSP1_NEUCR  (O60045), STXB4_HUMAN (Q6ZWJ1), 
STXB4_MOUSE (Q9WV89), SUDX_DROME  (Q9Y0H4), TCRG1_HUMAN (O14776), 
TCRG1_MOUSE (Q8CGF7), TCRGL_HUMAN (Q5VWI1), TCRGL_MOUSE (Q3B807), 
TG325_CAEEL (P46941), URN1_YEAST  (Q06525), UTRN_HUMAN  (P46939), 
UTRN_RAT(G3V7L1), WAC_DANRE   (Q7ZUK7), WAC_DROME   (Q9VX88), 
WAC_HUMAN   (Q9BTA9), WAC_MOUSE   (Q924H7), WAC_XENTR   (Q5U4Q0), 
WBP4_CHICK  (Q5F457), WBP4_HUMAN  (O75554), WBP4_MOUSE  (Q61048), 
WBP4_RAT(Q5HZF2), WWC2_HUMAN  (Q6AWC2), WWC2_MOUSE  (Q6NXJ0), 
WWC2_XENTR  (Q6DJR2), WWC3_HUMAN  (Q9ULE0), WWM1_YEAST  (P43582), 
WWOX_CHICK  (Q5F389), WWOX_DANRE  (Q803A8), WWOX_HUMAN  (Q9NZC7), 
WWOX_MOUSE  (Q91WL8), WWOX_PONAB  (Q5R9W5), WWP1_CAEEL  (Q9N2Z7), 
WWP1_HUMAN  (Q9H0M0), WWP1_MOUSE  (Q8BZZ3), WWP2_HUMAN  (O00308), 
WWP2_MOUSE  (Q9DBH0), WWTR1_CANLF (A0A8I3PQN6), WWTR1_HUMAN (Q9GZV5), 
WWTR1_MOUSE (Q9EPK5), YAP1A_XENLA (D6C652), YAP1_CAEEL  (Q19404), 
YAP1_CANLF  (A0A8C0NGY6), YAP1_CHICK  (P46936), YAP1_DANRE  (Q1L8J7), 
YAP1_DROME  (Q45VV3), YAP1_HUMAN  (P46937), YAP1_MOUSE  (P46938), 
YAP1_ORYLA  (H2LBU8), YAP1_RAT(Q2EJA0), YO61_CAEEL  (P34600), 
ZYS3_CHLRE  (Q8GSP8)
» more

UniProtKB/Swiss-Prot
False negative sequences		 62 sequences 

CAPAM_HUMAN (Q9H4Z3), CAPAM_MOUSE (P59114), CE164_HUMAN (Q9UPV0), 

CE164_MOUSE (Q5DU05), CFL1_ARATH  (Q5HZ54), CFL1_ORYSI  (B8AIM8), 
CFL1_ORYSJ  (Q0E0W7), CFL2_ARATH  (Q9C7E6), CMTR1_MOUSE (Q9DBC3), 
CMTR1_RAT   (Q5U2Z5), DGCR8_BOVIN (A6QR44), DGCR8_HUMAN (Q8WYQ5), 
DGCR8_MOUSE (Q9EQM6), DMDA_DROME  (Q9VDW6), DMDB_DROME  (Q9VDW3), 
DMDD_DROME  (Q0KI50), DMDE_DROME  (Q7YU29), FCA_ARATH   (O04425), 
FCA_ORYSI   (B8BCZ8), FCA_ORYSJ   (Q6K271), FEH1_CAEEL  (Q9BKZ9), 
FRPD4_HUMAN (Q14CM0), FRPD4_MOUSE (A2AFR3), NCFA_DICDI  (Q867T7), 
PIN1_RHIO9  (P0C1J8), PIN1_SCHPO  (O74448), PQBP1_BOVIN (Q2HJC9), 
PQBP1_GORGO (A1YFA7), PQBP1_HUMAN (O60828), PQBP1_MOUSE (Q91VJ5), 
PQBP1_PONPY (A2T806), PQBP1_RAT   (Q6PCT5), PR40A_ARATH (B6EUA9), 
PRP40_SCHPO (O14176), RH14_ORYSJ  (Q5VQL1), RHG09_HUMAN (Q9BRR9), 
RHG12_HUMAN (Q8IWW6), RHG12_MACFA (Q9BE31), RHG12_MOUSE (Q8C0D4), 
RHG27_HUMAN (Q6ZUM4), RHG27_MOUSE (A2AB59), RHG27_RAT   (Q6TLK4), 
RHG39_HUMAN (Q9C0H5), RHG39_MOUSE (P59281), SAV1_HUMAN  (Q9H4B6), 
SAV1_MOUSE  (Q8VEB2), SAV1_RAT(A4V8B4), SAV_DROME   (Q9VCR6), 
SEC24_CRYNB (P0CR41), SEC24_CRYNJ (P0CR40), SET2_ASPFU  (Q4WTT2), 
SET2_CANGA  (Q6FX50), SET2_DEBHA  (Q6BM04), SET2_EREGS  (Q757Y8), 
SET2_KLULA  (Q6CXP5), SET2_YARLI  (Q6C5G5), SET2_YEAST  (P46995), 
WWOX_DROME  (Q9VLU5), YERE_SCHPO  (O14097), YHK5_SCHPO  (O94425), 
YHK6_SCHPO  (O94426), YNI8_SCHPO  (O13598)
» more

UniProtKB/Swiss-Prot
False positive sequences		 59 sequences 

ACCD_AFIC5  (B6JCP4), ACCD_AZOC5  (A8HQ90), ACCD_BARBK  (A1UUE5), 

ACCD_BARHE  (Q6G581), ACCD_BARQU  (Q6G1D3), ACCD_BRADU  (Q89WE3), 
ACCD_BRASB  (A5E8A2), ACCD_BRASO  (A4YJI4), ACCD_BRUA1  (B2S9A2), 
ACCD_BRUA2  (Q2YQW8), ACCD_BRUA4  (A6WX31), ACCD_BRUAB  (Q57AF3), 
ACCD_BRUC2  (A9M9T9), ACCD_BRUMB  (C0RFZ1), ACCD_BRUME  (Q8YE58), 
ACCD_BRUO2  (A5VT60), ACCD_BRUSI  (B0CJK5), ACCD_BRUSU  (Q8FXY7), 
ACCD_CHESB  (Q11KL2), ACCD_CLOD6  (Q187P6), ACCD_NITHX  (Q1QS35), 
ACCD_NITWN  (Q3SWM0), ACCD_RHILO  (Q98CN5), ACCD_RHOP2  (Q2J2G6), 
ACCD_RHOP5  (Q07UG9), ACCD_RHOPA  (Q6NDN4), ACCD_RHOPB  (Q21CC1), 
ACCD_RHOPS  (Q13EQ0), ACCD_RHOPT  (B3Q607), AGAL1_ARATH (Q9FT97), 
ALG9_YEAST  (P53868), AMO_PICAN   (P12807), ANA_DROME   (Q26307), 
ANKY1_HUMAN (Q9P2S6), ANMY1_MOUSE (Q8C0W1), AUS1_YEAST  (Q08409), 
CLAG_PENCR  (A0A481WQK1), DOA10_YEAST (P40318), DPFGJ_GIBZE (I1RL13), 
FUM1_GIBM7  (W7LKX1), GALT9_HUMAN (Q9HCQ5), GALT9_MACFA (Q9GM01), 
LENG8_XENLA (Q32NW2), MATK_AVIMR  (Q766U5), MATK_BYBLI  (Q8MA72), 
MATK_CHLSC  (A6MMA3), MATK_COLSP  (Q9GHE2), MATK_DIOEL  (A6MMI9), 
MATK_DISSE  (Q9GHE1), MATK_FICCA  (Q85V93), MATK_IMPCA  (Q8M9L8), 
MF6LB_XENLA (Q5XGZ9), NIPA1_HUMAN (Q7RTP0), NIPA1_MOUSE (Q8BHK1), 
NIVU2_EUPNI (P86837), PALB_CANAL  (Q5AK25), PHT14_PETHY (B2CPI6), 
PHT15_PETHY (B2CPI7), YI31_SCHPO  (Q9HE12)
» more

PDB
[Detailed view]		 215 PDB

pdb_00001e0l; pdb_00001eg3; pdb_00001eg4; pdb_00001f8a; pdb_00001i5h; pdb_00001i6c; pdb_00001i8g; pdb_00001i8h; pdb_00001jmq; pdb_00001k5r; pdb_00001k9q; pdb_00001k9r; pdb_00001nmv; pdb_00001o6w; pdb_00001pin; pdb_00001tk7; pdb_00001wmv; pdb_00001wr3; pdb_00001wr4; pdb_00001wr7; pdb_00001yiu; pdb_00001ywi; pdb_00001ywj; pdb_00001zcn; pdb_00001zr7; pdb_00002djy; pdb_00002dk1; pdb_00002dmv; pdb_00002dyf; pdb_00002e45; pdb_00002ez5; pdb_00002f21; pdb_00002ho2; pdb_00002idh; pdb_00002itk; pdb_00002jmf; pdb_00002jo9; pdb_00002joc; pdb_00002jup; pdb_00002jxw; pdb_00002kbu; pdb_00002kcf; pdb_00002kpz; pdb_00002kq0; pdb_00002kxq; pdb_00002kyk; pdb_00002l5f; pdb_00002laj; pdb_00002law; pdb_00002lax; pdb_00002lay; pdb_00002lb1; pdb_00002lb2; pdb_00002lb3; pdb_00002ltv; pdb_00002ltw; pdb_00002ltx; pdb_00002lty; pdb_00002ltz; pdb_00002m3o; pdb_00002m8i; pdb_00002m8j; pdb_00002m9e; pdb_00002m9f; pdb_00002m9i; pdb_00002m9j; pdb_00002mdc; pdb_00002mdi; pdb_00002mdj; pdb_00002mpt; pdb_00002mw9; pdb_00002mwa; pdb_00002mwb; pdb_00002mwd; pdb_00002mwe; pdb_00002mwf; pdb_00002n1o; pdb_00002n4r; pdb_00002n4s; pdb_00002n4t; pdb_00002n4u; pdb_00002n8s; pdb_00002n8t; pdb_00002n8u; pdb_00002nnt; pdb_00002oei; pdb_00002op7; pdb_00002q5a; pdb_00002rly; pdb_00002rm0; pdb_00002xp3; pdb_00002xp4; pdb_00002xp5; pdb_00002xp6; pdb_00002xp7; pdb_00002xp8; pdb_00002xp9; pdb_00002xpa; pdb_00002xpb; pdb_00002ysc; pdb_00002ysd; pdb_00002yse; pdb_00002ysf; pdb_00002ysg; pdb_00002ysh; pdb_00002zaj; pdb_00002zqs; pdb_00002zqt; pdb_00002zqv; pdb_00002zr5; pdb_00002zr6; pdb_00003kab; pdb_00003kad; pdb_00003kaf; pdb_00003kag; pdb_00003kah; pdb_00003kai; pdb_00003kce; pdb_00003l4h; pdb_00003ntp; pdb_00003odk; pdb_00003olm; pdb_00003oob; pdb_00003tc5; pdb_00003tcz; pdb_00003tdb; pdb_00003wh0; pdb_00004gwt; pdb_00004gwv; pdb_00004lcd; pdb_00004n7f; pdb_00004n7h; pdb_00004qib; pdb_00004rex; pdb_00004rof; pdb_00004u84; pdb_00004u85; pdb_00004u86; pdb_00005aht; pdb_00005b3z; pdb_00005cq2; pdb_00005dws; pdb_00005dzd; pdb_00005o9z; pdb_00005tj7; pdb_00005tj8; pdb_00005tjq; pdb_00005uy9; pdb_00005vti; pdb_00005vtj; pdb_00005vtk; pdb_00005xmc; pdb_00005ydx; pdb_00005ydy; pdb_00006ahd; pdb_00006iko; pdb_00006j1x; pdb_00006j1y; pdb_00006j1z; pdb_00006j68; pdb_00006j69; pdb_00006jjw; pdb_00006jjx; pdb_00006jjy; pdb_00006jjz; pdb_00006jk0; pdb_00006jk1; pdb_00006kkg; pdb_00006n7p; pdb_00006o33; pdb_00006rss; pdb_00006svc; pdb_00006sve; pdb_00006svh; pdb_00006vaj; pdb_00007abf; pdb_00007abg; pdb_00007efj; pdb_00007efx; pdb_00007ekv; pdb_00007f0m; pdb_00007kkf; pdb_00007lp1; pdb_00007lp2; pdb_00007lp3; pdb_00007lp4; pdb_00007lp5; pdb_00007nmz; pdb_00007oqe; pdb_00007sa5; pdb_00007suq; pdb_00007sur; pdb_00008h6k; pdb_00008h6l; pdb_00008p4e; pdb_00008p4f; pdb_00008pxw; pdb_00008pxx; pdb_00008q7n; pdb_00008qo9; pdb_00008qpe; pdb_00008qzs; pdb_00008sg2; pdb_00008vjd; pdb_00008vje; pdb_00008vjf; pdb_00008vjg; pdb_00008w8f; pdb_00009egz; pdb_00009eh0; pdb_00009eh2; pdb_00009eqh; pdb_00009eqk; pdb_00009inr; pdb_00009it1
» more