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Entry: PS01173

General information about the entry

Entry name [info] LIPASE_GDXG_HIS
Accession [info] PS01173
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-APR-2006 DATA UPDATE;
13-NOV-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00903

Name and characterization of the entry

Description [info] Lipolytic enzymes "G-D-X-G" family, putative histidine active site.
Pattern [info] 
[LIVMF](2)-x-[LIVMF]-H-G-G-[SAG]-[FYW]-x(3)-[STDN]-x(1,2)-[STYA]-[HAGFT].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_10 which contains 561'356 sequence entries.


Total number of hits 48 in 48 different sequences
Number of true positive hits 48 in 48 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 39
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 55.17 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 4
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 48 sequences 

AAAD_MOUSE  (Q99PG0    ), AAAD_RAT    (Q9QZH8    ), AES_ECO24   (A7ZIN6    ), 

AES_ECO27   (B7UKF6    ), AES_ECO45   (B7MDZ8    ), AES_ECO55   (B7L7A1    ), 
AES_ECO57   (Q8XD38    ), AES_ECO5E   (B5Z3Y7    ), AES_ECO7I   (B7NIF4    ), 
AES_ECO81   (B7MQJ1    ), AES_ECO8A   (B7M3W8    ), AES_ECOBW   (C4ZUT0    ), 
AES_ECODH   (B1XFR3    ), AES_ECOHS   (A7ZXD4    ), AES_ECOK1   (A1A8E2    ), 
AES_ECOL5   (Q0TKG5    ), AES_ECOL6   (Q8FK82    ), AES_ECOLC   (B1IZB8    ), 
AES_ECOLI   (P23872    ), AES_ECOLU   (B7N929    ), AES_ECOSE   (B6I0B9    ), 
AES_ECOSM   (B1LJN4    ), AES_ECOUT   (Q1RF59    ), AES_SHIB3   (B2U4S9    ), 
AES_SHIBS   (Q325C0    ), AES_SHIF8   (Q0T7A9    ), AES_SHIFL   (Q83M39    ), 
AES_SHISS   (Q3Z4S3    ), BAH_STRHY   (Q01109    ), CXE16_ARATH (Q8LED9    ), 
CXE1_ACTER  (Q0ZPV7    ), CXE1_PAPSO  (I3PLR2    ), CXE2_ARATH  (Q9SX78    ), 
CXE2_PAPSO  (A0A0A1EQ07), CXE8_ARATH  (O64640    ), EST_ACILW   (P18773    ), 
GID1A_ARATH (Q9MAA7    ), GID1B_ARATH (Q9LYC1    ), GID1C_ARATH (Q940G6    ), 
GID1_ORYSJ  (Q6L545    ), HIDH_SOYBN  (Q5NUF3    ), LIP2_MORS1  (P24484    ), 
LIPS_BOVIN  (P16386    ), LIPS_HUMAN  (Q05469    ), LIPS_ICTTR  (Q9R101    ), 
LIPS_MOUSE  (P54310    ), LIPS_PIG    (Q68J42    ), LIPS_RAT    (P15304    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 39 sequences 

AAAD_HUMAN  (P22760    ), AAAD_RABIT  (Q7M370    ), ADCL2_HUMAN (Q6P093    ), 

ADCL3_HUMAN (Q5VUY0    ), ADCL3_MOUSE (A2A7Z8    ), ADCL4_HUMAN (Q5VUY2    ), 
ADCL4_MOUSE (Q8BM81    ), AES_SALA4   (B5EXN3    ), AES_SALCH   (Q57S73    ), 
AES_SALDC   (B5FLK0    ), AES_SALEP   (B5QU79    ), AES_SALNS   (B4SWY4    ), 
AES_SALPA   (Q5PFJ2    ), AES_SALPB   (A9MW81    ), AES_SALPK   (B5BD42    ), 
AES_SALSV   (B4TMG8    ), AES_SALTI   (Q8Z8T1    ), AES_SALTY   (Q8ZRA1    ), 
CXE11_ARATH (Q9LK21    ), CXE12_ARATH (Q9SMN0    ), CXE13_ARATH (Q9SMM9    ), 
CXE15_ARATH (Q9FG13    ), CXE17_ARATH (Q9LFR7    ), CXE18_ARATH (Q9LT10    ), 
CXE1_ARATH  (Q9LMA7    ), CXE20_ARATH (Q9LVB8    ), CXE3_ARATH  (Q9FX92    ), 
CXE4_ARATH  (Q9FX93    ), CXE5_ARATH  (Q9FX94    ), CXE6_ARATH  (Q9SX25    ), 
CXE7_ARATH  (Q9ZQ91    ), CXE9_ARATH  (O64641    ), LIPR_MYCTO  (P9WK84    ), 
LIPR_MYCTU  (P9WK85    ), LIPY_MYCTU  (I6Y2J4    ), MLHB_RHOER  (Q9EX73    ), 
NCEH1_HUMAN (Q6PIU2    ), NCEH1_MOUSE (Q8BLF1    ), NCEH1_PONAB (Q5R8Y5    )
» more

PDB
[Detailed view]		 8 PDB

2O7R; 2O7V; 2ZSH; 2ZSI; 3EBL; 3ED1; 4KRX; 4KRY

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