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PROSITE entry PS01174


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General information about the entry

Entry name [info] LIPASE_GDXG_SER
Accession [info] PS01174
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00903
Associated ProRule [info] PRU10038

Name and characterization of the entry

Description [info] Lipolytic enzymes "G-D-X-G" family, putative serine active site.
Pattern [info]
[LIVM]-x-[LIVMF]-[SA]-G-D-S-[CAS]-G-[GA]-x-[LI]-[CAVT].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 71 in 71 different sequences
Number of true positive hits 71 in 71 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 30
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 70.30 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
71 sequences

AAAD_BOVIN  (Q0P5B7), AAAD_HUMAN  (P22760), AAAD_MOUSE  (Q99PG0), 
AAAD_RABIT  (Q7M370), AAAD_RAT(Q9QZH8), ADCL2_HUMAN (Q6P093), 
AES_ECO24   (A7ZIN6), AES_ECO27   (B7UKF6), AES_ECO45   (B7MDZ8), 
AES_ECO55   (B7L7A1), AES_ECO57   (Q8XD38), AES_ECO5E   (B5Z3Y7), 
AES_ECO7I   (B7NIF4), AES_ECO81   (B7MQJ1), AES_ECO8A   (B7M3W8), 
AES_ECOBW   (C4ZUT0), AES_ECODH   (B1XFR3), AES_ECOHS   (A7ZXD4), 
AES_ECOK1   (A1A8E2), AES_ECOL5   (Q0TKG5), AES_ECOL6   (Q8FK82), 
AES_ECOLC   (B1IZB8), AES_ECOLI   (P23872), AES_ECOLU   (B7N929), 
AES_ECOSE   (B6I0B9), AES_ECOSM   (B1LJN4), AES_ECOUT   (Q1RF59), 
AES_SALA4   (B5EXN3), AES_SALCH   (Q57S73), AES_SALDC   (B5FLK0), 
AES_SALEP   (B5QU79), AES_SALNS   (B4SWY4), AES_SALPA   (Q5PFJ2), 
AES_SALPB   (A9MW81), AES_SALPK   (B5BD42), AES_SALSV   (B4TMG8), 
AES_SALTI   (Q8Z8T1), AES_SALTY   (Q8ZRA1), AES_SHIB3   (B2U4S9), 
AES_SHIBS   (Q325C0), AES_SHIF8   (Q0T7A9), AES_SHIFL   (Q83M39), 
AES_SHISS   (Q3Z4S3), BAH_STRHY   (Q01109), CXE12_ARATH (Q9SMN0), 
CXE13_ARATH (Q9SMM9), CXE17_ARATH (Q9LFR7), CXE1_ARATH  (Q9LMA7), 
CXE6_ARATH  (Q9SX25), EST_ACIVR   (P18773), GID1A_ARATH (Q9MAA7), 
GID1B_ARATH (Q9LYC1), GID1C_ARATH (Q940G6), GID1_ORYSJ  (Q6L545), 
LIP2_MORS1  (P24484), LIPF_MYCTO  (Q7D5F9), LIPF_MYCTU  (O06350), 
LIPI_MYCTU  (P71668), LIPS_BOVIN  (P16386), LIPS_HUMAN  (Q05469), 
LIPS_ICTTR  (Q9R101), LIPS_MOUSE  (P54310), LIPS_PIG(Q68J42), 
LIPS_RAT(P15304), LIPU_MYCTU  (O53424), NCEH1_BOVIN (Q1JQE6), 
NCEH1_HUMAN (Q6PIU2), NCEH1_MOUSE (Q8BLF1), NCEH1_PONAB (Q5R8Y5), 
NCEH1_RAT   (B2GV54), TCEB1_TULGE (A0A0H5BMX5)
» more

UniProtKB/Swiss-Prot
False negative sequences
30 sequences

AD4F1_MOUSE (Q8BM81), ADCL3_HUMAN (Q5VUY0), ADCL3_MOUSE (A2A7Z8), 
ADCL4_HUMAN (Q5VUY2), CXE11_ARATH (Q9LK21), CXE15_ARATH (Q9FG13), 
CXE16_ARATH (Q8LED9), CXE18_ARATH (Q9LT10), CXE1_ACTER  (Q0ZPV7), 
CXE1_PAPSO  (I3PLR2), CXE20_ARATH (Q9LVB8), CXE2_ARATH  (Q9SX78), 
CXE2_PAPSO  (A0A0A1EQ07), CXE3_ARATH  (Q9FX92), CXE4_ARATH  (Q9FX93), 
CXE5_ARATH  (Q9FX94), CXE7_ARATH  (Q9ZQ91), CXE8_ARATH  (O64640), 
CXE9_ARATH  (O64641), ESTZ_PSEPU  (Q8KQK1), LIPC_MYCTU  (P96402), 
LIPM_MYCTU  (Q50681), LIPN_MYCTU  (P95125), LIPQ_MYCTU  (I6Y9F7), 
LIPR_MYCTO  (P9WK84), LIPR_MYCTU  (P9WK85), LIPY_MYCTU  (I6Y2J4), 
MLHB_RHOER  (Q9EX73), NLHH_MYCTO  (P9WK86), NLHH_MYCTU  (P9WK87)
» more

PDB
[Detailed view]
7 PDB

2ZSH; 2ZSI; 3EBL; 3ED1; 3GA7; 4KRX; 4KRY