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PROSITE entry PS01177


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01177
Entry name [info] ANAPHYLATOXIN_1
Accession [info] PS01177
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-MAY-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00906

Name and characterization of the entry

Description [info] Anaphylatoxin domain signature.
Pattern [info] 
[CSH]-C-x(2)-[GAP]-x(7,8)-[GASTDEQR]-C-[GASTDEQL]-x(3,9)-[GASTDEQN]-x(2)-
[CE]-x(6,7)-C-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 41 in 33 different sequences
Number of true positive hits 38 in 30 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 92.68 %
Recall (true positives / (true positives + false negatives)) 92.68 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 7
Site [info] disulfide at position 12
Site [info] disulfide at position 14
Site [info] disulfide at position 15
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 30 sequences 

CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), CO3_HUMAN   (P01024), 

CO3_LETCA   (Q00685), CO3_MOUSE   (P01027), CO3_NAJNA   (Q01833), 
CO3_ONCMY   (P98093), CO3_PIG (P01025), CO3_RAT (P01026), 
CO4A_HUMAN  (P0C0L4), CO4B_HUMAN  (P0C0L5), CO4B_MOUSE  (P01029), 
CO4_BOVIN   (P01030), CO4_RAT (P08649), CO5_BOVIN   (P12082), 
CO5_HUMAN   (P01031), CO5_MOUSE   (P06684), CO5_PIG (P01032), 
CO5_RAT (P08650), FBLN1_CAEEL (O77469), FBLN1_CHICK (O73775), 
FBLN1_CHLAE (Q8MJJ9), FBLN1_DANRE (O42182), FBLN1_HUMAN (P23142), 
FBLN1_MOUSE (Q08879), FBLN2_HUMAN (P98095), FBLN2_MOUSE (P37889), 
VCO31_AUSSU (Q0ZZJ6), VCO32_AUSSU (A0RZC6), VCO3_CROAD  (J3S836)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

CO3_BOVIN   (Q2UVX4), VCO3_NAJKA  (Q91132), VCO3_OPHHA  (I2C090)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			3 sequences
			


			
CO3_RABIT   (P12247), CO3_XENLA   (P23667), CO4_CAVPO   (P19069)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
A7466_ARTBC (D4ATA2), FRAS1_MOUSE (Q80T14), KRA51_MOUSE (Q64507)


				
	

	

		PDB
[Detailed view]		
		
			48 PDB
			


			1C5A; 1CFA; 1KJS; 2A73; 3CU7; 3HQA; 3HQB; 3KLS; 3KM9; 3PRX; 3PVM; 4E0S; 
			
				4HW5; 4HWJ; 4I6O; 4P39; 4P3A; 4P3B; 4UU9; 4WB2; 4WB3; 5B4P; 5HCC; 5HCD; 
				5HCE; 5I5K; 5JPM; 5JPN; 6JV7; 6JV8; 6RQJ; 7AD6; 7AD7; 7NYC; 7NYD; 7Y64; 
				8AYH; 8B0F; 8B0G; 8B0H; 8HK2; 8HK5; 8HQC; 8I9L; 8IA2; 8JZZ; 8OQ3; 8R5W
			
			

			» more