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PROSITE entry PS01177


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PURL: https://purl.expasy.org/prosite/signature/PS01177

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General information about the entry

Entry name [info] ANAPHYLATOXIN_1
Accession [info] PS01177
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-MAY-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00906

Name and characterization of the entry

Description [info] Anaphylatoxin domain signature.
Pattern [info] 
[CSH]-C-x(2)-[GAP]-x(7,8)-[GASTDEQR]-C-[GASTDEQL]-x(3,9)-[GASTDEQN]-x(2)-
[CE]-x(6,7)-C-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 43 in 35 different sequences
Number of true positive hits 40 in 32 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 93.02 %
Recall (true positives / (true positives + false negatives)) 93.02 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 7
Site [info] disulfide at position 12
Site [info] disulfide at position 14
Site [info] disulfide at position 15
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 32 sequences 

CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), CO3_HUMAN   (P01024), 

CO3_LETCA   (Q00685), CO3_MOUSE   (P01027), CO3_NAJNA   (Q01833), 
CO3_ONCMY   (P98093), CO3_PIG (P01025), CO3_RAT (P01026), 
CO4A_HUMAN  (P0C0L4), CO4A_MOUSE  (A0AAQ4VMX2), CO4B_HUMAN  (P0C0L5), 
CO4B_MOUSE  (P01029), CO4_BOVIN   (P01030), CO4_CAVPO   (P19069), 
CO4_RAT (P08649), CO5_BOVIN   (P12082), CO5_HUMAN   (P01031), 
CO5_MOUSE   (P06684), CO5_PIG (P01032), CO5_RAT (P08650), 
FBLN1_CAEEL (O77469), FBLN1_CHICK (O73775), FBLN1_CHLAE (Q8MJJ9), 
FBLN1_DANRE (O42182), FBLN1_HUMAN (P23142), FBLN1_MOUSE (Q08879), 
FBLN2_HUMAN (P98095), FBLN2_MOUSE (P37889), VCO31_AUSSU (Q0ZZJ6), 
VCO32_AUSSU (A0RZC6), VCO3_CROAD  (J3S836)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

CO3_BOVIN   (Q2UVX4), VCO3_NAJKA  (Q91132), VCO3_OPHHA  (I2C090)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			2 sequences
			


			
CO3_RABIT   (P12247), CO3_XENLA   (P23667)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
A7466_ARTBC (D4ATA2), FRAS1_MOUSE (Q80T14), KRA51_MOUSE (Q64507)


				
	

	

		PDB
[Detailed view]		
		
			51 PDB
			


			pdb_00001c5a; pdb_00001cfa; pdb_00001kjs; pdb_00002a73; pdb_00003cu7; pdb_00003hqa; pdb_00003hqb; pdb_00003kls; pdb_00003km9; pdb_00003prx; pdb_00003pvm; pdb_00004e0s; 
			
				pdb_00004hw5; pdb_00004hwj; pdb_00004i6o; pdb_00004p39; pdb_00004p3a; pdb_00004p3b; pdb_00004uu9; pdb_00004wb2; pdb_00004wb3; pdb_00005b4p; pdb_00005hcc; pdb_00005hcd; 
				pdb_00005hce; pdb_00005i5k; pdb_00005jpm; pdb_00005jpn; pdb_00006jv7; pdb_00006jv8; pdb_00006rqj; pdb_00007ad6; pdb_00007ad7; pdb_00007b2m; pdb_00007b2p; pdb_00007b2q; 
				pdb_00007nyc; pdb_00007nyd; pdb_00007y64; pdb_00008ayh; pdb_00008b0f; pdb_00008b0g; pdb_00008b0h; pdb_00008hk2; pdb_00008hk5; pdb_00008hqc; pdb_00008i9l; pdb_00008ia2; 
				pdb_00008jzz; pdb_00008oq3; pdb_00008r5w
			
			

			» more