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PROSITE entry PS01178


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PURL: https://purl.expasy.org/prosite/signature/PS01178

Direct ScanProsite submission
General information about the entry

Entry name [info] ANAPHYLATOXIN_2
Accession [info] PS01178
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00906
Associated ProRule [info] PRU00022

Name and characterization of the entry

Description [info] Anaphylatoxin domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=34;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=34;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7140000; R2=0.0113000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=551.3717041; R2=3.3716815; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=628; H_SCORE=2669; N_SCORE=7.8; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=513; H_SCORE=2281; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 43 in 34 different sequences
Number of true positive hits 43 in 34 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.73 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] Anaphylatoxin-like
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
34 sequences

CO3_BOVIN   (Q2UVX4), CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

FBLN1_CAEEL (O77469)

		
UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

CO3_RABIT   (P12247), CO3_XENLA   (P23667)

		
PDB
[Detailed view]
52 PDB

1C5A; 1CFA; 1KJS; 2A73; 3CU7; 3HQA; 3HQB; 3KLS; 3KM9; 3PRX; 3PVM; 4E0S;
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