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PROSITE entry PS01208


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General information about the entry

Entry name [info] VWFC_1
Accession [info] PS01208
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00928

Name and characterization of the entry

Description [info] VWFC domain signature.
Pattern [info] 
C-x(2,3)-C-{CG}-C-x(6,14)-C-x(3,4)-C-x(2,10)-C-x(9,16)-C-C-x(2,4)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 285 in 145 different sequences
Number of true positive hits 249 in 120 different sequences
Number of 'unknown' hits 1
Number of false positive hits 35 in 24 different sequences
Number of false negative sequences 20
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 87.68 %
Recall (true positives / (true positives + false negatives)) 92.57 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 20
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 120 sequences 

BMPER_HUMAN (Q8N8U9), BMPER_MOUSE (Q8CJ69), CCN1_CHICK  (P19336), 

CCN1_HUMAN  (O00622), CCN1_MOUSE  (P18406), CCN1_PANTR  (A5A6L1), 
CCN1_RAT(Q9ES72), CCN2_BOVIN  (O18739), CCN2_HUMAN  (P29279), 
CCN2_MOUSE  (P29268), CCN2_PIG(O19113), CCN2_RAT(Q9R1E9), 
CCN3_CHICK  (P28686), CCN3_COTJA  (P42642), CCN3_HUMAN  (P48745), 
CCN3_MOUSE  (Q64299), CCN3_RAT(Q9QZQ5), CCN3_XENLA  (P51609), 
CCN4_HUMAN  (O95388), CCN4_MOUSE  (O54775), CCN4_RAT(Q99PP0), 
CCN5_HUMAN  (O76076), CCN5_MOUSE  (Q9Z0G4), CCN5_RAT(Q9JHC6), 
CHRD_DANRE  (O57472), CHRD_HUMAN  (Q9H2X0), CHRD_MOUSE  (Q9Z0E2), 
CHRD_RAT(Q63148), CHRD_XENLA  (Q91713), CO1A1_BOVIN (P02453), 
CO1A1_CANLF (Q9XSJ7), CO1A1_CHICK (P02457), CO1A1_CYNPY (Q9YIB4), 
CO1A1_HUMAN (P02452), CO1A1_MOUSE (P11087), CO1A1_RAT   (P02454), 
CO2A1_BOVIN (P02459), CO2A1_HUMAN (P02458), CO2A1_MOUSE (P28481), 
CO2A1_XENLA (Q91717), CO2A1_XENTR (Q6P4Z2), CO3A1_CHICK (P12105), 
CO3A1_HUMAN (P02461), CO3A1_MOUSE (P08121), CO3A1_RAT   (P13941), 
CO5A2_HUMAN (P05997), CO5A2_MOUSE (Q3U962), CRDL1_CHICK (Q90ZD5), 
CRDL1_HUMAN (Q9BU40), CRDL1_MOUSE (Q920C1), CRDL1_RAT   (Q76LD0), 
CRDL2_HUMAN (Q6WN34), CRDL2_MOUSE (Q8VEA6), CRIM1_CHICK (Q8AWW5), 
CRIM1_DANRE (Q7T3Q2), CRIM1_HUMAN (Q9NZV1), CRIM1_MOUSE (Q9JLL0), 
ECM2_BOVIN  (Q3MHH9), ECM2_HUMAN  (O94769), ECM2_MOUSE  (Q5FW85), 
FRAS1_HUMAN (Q86XX4), FRAS1_MOUSE (Q80T14), IDD_HUMAN   (P98153), 
IDD_MOUSE   (P98154), KCP_HUMAN   (Q6ZWJ8), KCP_MOUSE   (Q3U492), 
KCP_XENLA   (Q9IBG7), MUC19_BOVIN (P98091), MUC19_MOUSE (Q6PZE0), 
MUC2L_RAT   (P98089), MUC2_HUMAN  (Q02817), MUC2_MOUSE  (Q80Z19), 
MUC5A_HUMAN (P98088), MUC5B_CHICK (Q98UI9), MUC5B_HUMAN (Q9HC84), 
MUCAP_PIG   (P12021), MUCB1_XENLA (P38565), NELL1_HUMAN (Q92832), 
NELL1_MOUSE (Q2VWQ2), NELL1_RAT   (Q62919), NELL2_BOVIN (A6QR11), 
NELL2_DANRE (A1A5Y0), NELL2_HUMAN (Q99435), NELL2_MOUSE (Q61220), 
NELL2_PONAB (Q5R3Z7), NELL2_RAT   (Q62918), NELL2_XENLA (Q7ZXL5), 
NELL2_XENTR (A2VCU8), NEL_CHICK   (Q90827), PXDNL_HUMAN (A1KZ92), 
PXDN_DROME  (Q9VZZ4), PXDN_HUMAN  (Q92626), PXDN_MOUSE  (Q3UQ28), 
PXDN_XENTR  (A4IGL7), SAS_DROME   (Q04164), SOG_DROME   (Q24025), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT(Q700K0), TSP1_BOVIN  (Q28178), 
TSP1_HUMAN  (P07996), TSP1_MOUSE  (P35441), TSP1_XENLA  (P35448), 
TSP2_BOVIN  (Q95116), TSP2_CHICK  (P35440), TSP2_HUMAN  (P35442), 
TSP2_MOUSE  (Q03350), VWC2L_DANRE (B0UZC8), VWC2L_HUMAN (B2RUY7), 
VWC2L_MOUSE (Q505H4), VWC2_HUMAN  (Q2TAL6), VWC2_MOUSE  (Q8C8N3), 
VWCE_HUMAN  (Q96DN2), VWCE_MOUSE  (Q3U515), VWF_CANLF   (Q28295), 
VWF_HUMAN   (P04275), VWF_MOUSE   (Q8CIZ8), VWF_PIG (Q28833)
» more

UniProtKB/Swiss-Prot
False negative sequences		 20 sequences 

AMNLS_CANLF (Q6UKI2), AMNLS_HUMAN (Q9BXJ7), AMNLS_MOUSE (Q99JB7), 

AMNLS_PIG   (F1SAM7), FSTL1_BOVIN (Q58D84), FSTL1_HUMAN (Q12841), 
FSTL1_MACFA (Q9GKY0), FSTL1_MOUSE (Q62356), FSTL1_PONAB (Q5R9Y1), 
FSTL1_RAT   (Q62632), HMCT_BOMMO  (P98092), JAG1B_DANRE (Q90Y54), 
JAG2_HUMAN  (Q9Y219), MUC19_HUMAN (Q7Z5P9), MUC2_RAT(Q62635), 
VWC2L_MACFA (Q95K75), ZAN_HUMAN   (Q9Y493), ZAN_MOUSE   (O88799), 
ZAN_PIG (Q28983), ZAN_RABIT   (P57999)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

CO1A1_RABIT (P02456), CO2A1_CHICK (P02460), CO3A1_BOVIN (P04258), 

VWF_BOVIN   (P80012)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

SCGR7_HUMAN (A0A286YF01)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			24 sequences
			


			
DEP1_ORYSJ  (Q67UU9), GG3_ARATH   (Q6AWT8), KR510_HUMAN (Q6L8G5), 

			
KRA51_HUMAN (Q6L8H4), KRA51_MOUSE (Q64507), KRA53_HUMAN (Q6L8H2), 
KRA54_HUMAN (Q6L8H1), KRA56_HUMAN (Q6L8G9), KRA57_HUMAN (Q6L8G8), 
KRA58_HUMAN (O75690), KRA59_HUMAN (P26371), KRUC_SHEEP  (P26372), 
MCSP_MOUSE  (P15265), MCSP_RAT(Q64298), MTCU_CALSI  (Q9U620), 
MT_CARMA(P55948), SCGR1_HUMAN (A0A286YEY9), SCGR2_HUMAN (A0A286YFB4), 
SCGR3_HUMAN (A0A286YF60), SCGR4_HUMAN (A0A286YEV6), SCGR5_HUMAN (A0A286YF46), 
SCGR6_HUMAN (A0A286YF77), SCGR8_HUMAN (A0A286YFG1), SCGR9_HUMAN (P0DSO2)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			5 PDB
			


			1U5M; 5NB8; 5NIR; 7QCL; 7QCU