PROSITE logo

PROSITE entry PS01208


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01208
Entry name [info] VWFC_1
Accession [info] PS01208
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00928

Name and characterization of the entry

Description [info] VWFC domain signature.
Pattern [info] 
C-x(2,3)-C-{CG}-C-x(6,14)-C-x(3,4)-C-x(2,10)-C-x(9,16)-C-C-x(2,4)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 285 in 145 different sequences
Number of true positive hits 249 in 120 different sequences
Number of 'unknown' hits 1
Number of false positive hits 35 in 24 different sequences
Number of false negative sequences 20
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 87.68 %
Recall (true positives / (true positives + false negatives)) 92.57 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 20
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 120 sequences 

BMPER_HUMAN (Q8N8U9), BMPER_MOUSE (Q8CJ69), CCN1_CHICK  (P19336), 

CCN1_HUMAN  (O00622), CCN1_MOUSE  (P18406), CCN1_PANTR  (A5A6L1), 
CCN1_RAT(Q9ES72), CCN2_BOVIN  (O18739), CCN2_HUMAN  (P29279), 
CCN2_MOUSE  (P29268), CCN2_PIG(O19113), CCN2_RAT(Q9R1E9), 
CCN3_CHICK  (P28686), CCN3_COTJA  (P42642), CCN3_HUMAN  (P48745), 
CCN3_MOUSE  (Q64299), CCN3_RAT(Q9QZQ5), CCN3_XENLA  (P51609), 
CCN4_HUMAN  (O95388), CCN4_MOUSE  (O54775), CCN4_RAT(Q99PP0), 
CCN5_HUMAN  (O76076), CCN5_MOUSE  (Q9Z0G4), CCN5_RAT(Q9JHC6), 
CHRD_DANRE  (O57472), CHRD_HUMAN  (Q9H2X0), CHRD_MOUSE  (Q9Z0E2), 
CHRD_RAT(Q63148), CHRD_XENLA  (Q91713), CO1A1_BOVIN (P02453), 
CO1A1_CANLF (Q9XSJ7), CO1A1_CHICK (P02457), CO1A1_CYNPY (Q9YIB4), 
CO1A1_HUMAN (P02452), CO1A1_MOUSE (P11087), CO1A1_RAT   (P02454), 
CO2A1_BOVIN (P02459), CO2A1_HUMAN (P02458), CO2A1_MOUSE (P28481), 
CO2A1_XENLA (Q91717), CO2A1_XENTR (Q6P4Z2), CO3A1_CHICK (P12105), 
CO3A1_HUMAN (P02461), CO3A1_MOUSE (P08121), CO3A1_RAT   (P13941), 
CO5A2_HUMAN (P05997), CO5A2_MOUSE (Q3U962), CRDL1_CHICK (Q90ZD5), 
CRDL1_HUMAN (Q9BU40), CRDL1_MOUSE (Q920C1), CRDL1_RAT   (Q76LD0), 
CRDL2_HUMAN (Q6WN34), CRDL2_MOUSE (Q8VEA6), CRIM1_CHICK (Q8AWW5), 
CRIM1_DANRE (Q7T3Q2), CRIM1_HUMAN (Q9NZV1), CRIM1_MOUSE (Q9JLL0), 
ECM2_BOVIN  (Q3MHH9), ECM2_HUMAN  (O94769), ECM2_MOUSE  (Q5FW85), 
FRAS1_HUMAN (Q86XX4), FRAS1_MOUSE (Q80T14), IDD_HUMAN   (P98153), 
IDD_MOUSE   (P98154), KCP_HUMAN   (Q6ZWJ8), KCP_MOUSE   (Q3U492), 
KCP_XENLA   (Q9IBG7), MUC19_BOVIN (P98091), MUC19_MOUSE (Q6PZE0), 
MUC2L_RAT   (P98089), MUC2_HUMAN  (Q02817), MUC2_MOUSE  (Q80Z19), 
MUC5A_HUMAN (P98088), MUC5B_CHICK (Q98UI9), MUC5B_HUMAN (Q9HC84), 
MUCAP_PIG   (P12021), MUCB1_XENLA (P38565), NELL1_HUMAN (Q92832), 
NELL1_MOUSE (Q2VWQ2), NELL1_RAT   (Q62919), NELL2_BOVIN (A6QR11), 
NELL2_DANRE (A1A5Y0), NELL2_HUMAN (Q99435), NELL2_MOUSE (Q61220), 
NELL2_PONAB (Q5R3Z7), NELL2_RAT   (Q62918), NELL2_XENLA (Q7ZXL5), 
NELL2_XENTR (A2VCU8), NEL_CHICK   (Q90827), PXDNL_HUMAN (A1KZ92), 
PXDN_DROME  (Q9VZZ4), PXDN_HUMAN  (Q92626), PXDN_MOUSE  (Q3UQ28), 
PXDN_XENTR  (A4IGL7), SAS_DROME   (Q04164), SOG_DROME   (Q24025), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT(Q700K0), TSP1_BOVIN  (Q28178), 
TSP1_HUMAN  (P07996), TSP1_MOUSE  (P35441), TSP1_XENLA  (P35448), 
TSP2_BOVIN  (Q95116), TSP2_CHICK  (P35440), TSP2_HUMAN  (P35442), 
TSP2_MOUSE  (Q03350), VWC2L_DANRE (B0UZC8), VWC2L_HUMAN (B2RUY7), 
VWC2L_MOUSE (Q505H4), VWC2_HUMAN  (Q2TAL6), VWC2_MOUSE  (Q8C8N3), 
VWCE_HUMAN  (Q96DN2), VWCE_MOUSE  (Q3U515), VWF_CANLF   (Q28295), 
VWF_HUMAN   (P04275), VWF_MOUSE   (Q8CIZ8), VWF_PIG (Q28833)
» more

UniProtKB/Swiss-Prot
False negative sequences		 20 sequences 

AMNLS_CANLF (Q6UKI2), AMNLS_HUMAN (Q9BXJ7), AMNLS_MOUSE (Q99JB7), 

AMNLS_PIG   (F1SAM7), FSTL1_BOVIN (Q58D84), FSTL1_HUMAN (Q12841), 
FSTL1_MACFA (Q9GKY0), FSTL1_MOUSE (Q62356), FSTL1_PONAB (Q5R9Y1), 
FSTL1_RAT   (Q62632), HMCT_BOMMO  (P98092), JAG1B_DANRE (Q90Y54), 
JAG2_HUMAN  (Q9Y219), MUC19_HUMAN (Q7Z5P9), MUC2_RAT(Q62635), 
VWC2L_MACFA (Q95K75), ZAN_HUMAN   (Q9Y493), ZAN_MOUSE   (O88799), 
ZAN_PIG (Q28983), ZAN_RABIT   (P57999)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

CO1A1_RABIT (P02456), CO2A1_CHICK (P02460), CO3A1_BOVIN (P04258), 

VWF_BOVIN   (P80012)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

SCGR7_HUMAN (A0A286YF01)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			24 sequences
			


			
DEP1_ORYSJ  (Q67UU9), GG3_ARATH   (Q6AWT8), KR510_HUMAN (Q6L8G5), 

			
KRA51_HUMAN (Q6L8H4), KRA51_MOUSE (Q64507), KRA53_HUMAN (Q6L8H2), 
KRA54_HUMAN (Q6L8H1), KRA56_HUMAN (Q6L8G9), KRA57_HUMAN (Q6L8G8), 
KRA58_HUMAN (O75690), KRA59_HUMAN (P26371), KRUC_SHEEP  (P26372), 
MCSP_MOUSE  (P15265), MCSP_RAT(Q64298), MTCU_CALSI  (Q9U620), 
MT_CARMA(P55948), SCGR1_HUMAN (A0A286YEY9), SCGR2_HUMAN (A0A286YFB4), 
SCGR3_HUMAN (A0A286YF60), SCGR4_HUMAN (A0A286YEV6), SCGR5_HUMAN (A0A286YF46), 
SCGR6_HUMAN (A0A286YF77), SCGR8_HUMAN (A0A286YFG1), SCGR9_HUMAN (P0DSO2)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			5 PDB
			


			1U5M; 5NB8; 5NIR; 7QCL; 7QCU