PROSITE entry PS01248
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General information about the entry
Entry name [info] | EGF_LAM_1 |
Accession [info] | PS01248 |
Entry type [info] | PATTERN |
Date [info] |
01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00961 |
Name and characterization of the entry
Description [info] | Laminin-type EGF-like (LE) domain signature. |
Pattern [info] |
C-x(1,2)-C-x(5)-G-x(2)-C-x(2)-C-x(3,4)-[FYW]-x(3,15)-C. |
Numerical results [info]
Total number of hits | 584 in 139 different sequences |
Number of true positive hits | 527 in 95 different sequences |
Number of 'unknown' hits | 14 in 1 sequence |
Number of false positive hits | 43 in 43 different sequences |
Number of false negative sequences | 1 |
Number of 'partial' sequences | 1 |
Precision (true positives / (true positives + false positives)) | 92.46 % |
Recall (true positives / (true positives + false negatives)) | 99.81 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 21 |
Site [info] | disulfide at position 1 |
Site [info] | disulfide at position 3 |
Site [info] | disulfide at position 7 |
Site [info] | disulfide at position 9 |
Site [info] | disulfide at position 13 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
95 sequences
AGRIN_CHICK (P31696), AGRIN_DIPOM (Q90404), AGRIN_HUMAN (O00468), AGRIN_MOUSE (A2ASQ1), AGRIN_RAT (P25304), ATRN1_HUMAN (Q5VV63), ATRN1_MOUSE (Q6A051), ATRN_HUMAN (O75882), ATRN_MOUSE (Q9WU60), ATRN_RAT(Q99J86), CELR1_HUMAN (Q9NYQ6), CELR1_MOUSE (O35161), CELR2_HUMAN (Q9HCU4), CELR2_MOUSE (Q9R0M0), CELR2_RAT (Q9QYP2), CELR3_HUMAN (Q9NYQ7), CELR3_MOUSE (Q91ZI0), CELR3_RAT (O88278), CREL1_CAEEL (Q19267), CREL1_XENTR (A0A6I8RMG7), EPI1_CAEEL (Q21313), LAM2_CAEEL (Q18823), LAMA1_HUMAN (P25391), LAMA1_MOUSE (P19137), LAMA2_HUMAN (P24043), LAMA2_MOUSE (Q60675), LAMA3_HUMAN (Q16787), LAMA3_MOUSE (Q61789), LAMA4_HUMAN (Q16363), LAMA4_MOUSE (P97927), LAMA5_HUMAN (O15230), LAMA5_MOUSE (Q61001), LAMA_DROME (Q00174), LAMB1_CHICK (Q01635), LAMB1_DROME (P11046), LAMB1_HUMAN (P07942), LAMB1_HYDVU (Q27262), LAMB1_MOUSE (P02469), LAMB2_HUMAN (P55268), LAMB2_MOUSE (Q61292), LAMB2_RAT (P15800), LAMB3_HUMAN (Q13751), LAMB3_MOUSE (Q61087), LAMB4_DANRE (Q8JHV6), LAMB4_HUMAN (A4D0S4), LAMB_HIRME (Q25092), LAMC1_DANRE (Q1LVF0), LAMC1_DROME (P15215), LAMC1_HUMAN (P11047), LAMC1_MOUSE (P02468), LAMC1_XENTR (A0JP86), LAMC2_HORSE (Q8HZI9), LAMC2_HUMAN (Q13753), LAMC2_MOUSE (Q61092), LAMC3_HUMAN (Q9Y6N6), LAMC3_MOUSE (Q9R0B6), MEGF8_HUMAN (Q7Z7M0), MEGF8_MOUSE (P60882), MEGF8_RAT (Q9QYP0), MEGF9_HUMAN (Q9H1U4), MEGF9_MOUSE (Q8BH27), NET1_CHICK (Q90922), NET1_HUMAN (O95631), NET1_MOUSE (O09118), NET1_PIG(Q2HXW4), NET1_RAT(Q924Z9), NET3_CHICK (Q90923), NET3_HUMAN (O00634), NET3_MOUSE (Q9R1A3), NET4_HUMAN (Q9HB63), NET4_MOUSE (Q9JI33), NET4_PONAB (Q5RB89), NET5_HUMAN (Q8WTR8), NET5_MOUSE (Q3UQ22), NET5_RAT(D3ZT86), NETA_DROME (Q24567), NETB_DROME (Q24568), NTNG1_HUMAN (Q9Y2I2), NTNG1_MOUSE (Q8R4G0), NTNG2_HUMAN (Q96CW9), NTNG2_MOUSE (Q8R4F1), PGBM_HUMAN (P98160), PGBM_MOUSE (Q05793), STAB1_HUMAN (Q9NY15), STAB1_MOUSE (Q8R4Y4), STAB2_HUMAN (Q8WWQ8), STAB2_MOUSE (Q8R4U0), STAB2_RAT (Q8CFM6), STAN_DROME (Q9V5N8), TAG53_CAEEL (Q19981), UNC52_CAEEL (Q06561), UNC6_CAEEL (P34710), USH2A_HUMAN (O75445), USH2A_MOUSE (Q2QI47), USH2A_RAT (Q8K3K1)» more
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UniProtKB/Swiss-Prot False negative sequences |
1 sequence
SIGK_DICDI (Q6TMJ6) |
UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
LAMBV_CHICK (Q01636) |
UniProtKB/Swiss-Prot 'Unknown' sequences |
1 sequence
LAM3_CAEEL (G5ECE3) |
UniProtKB/Swiss-Prot False positive sequences |
43 sequences
ADP1_YEAST (P25371), CRE2A_XENLA (Q5XH36), CRE2B_XENLA (Q4V7M2), CREL1_BOVIN (Q5EA46), CREL1_HUMAN (Q96HD1), CREL1_MOUSE (Q91XD7), CREL1_RAT (Q4V7F2), CREL2_BOVIN (Q2KIT5), CREL2_CRIGR (Q60438), CREL2_DANRE (Q7SXF6), CREL2_HUMAN (Q6UXH1), CREL2_MOUSE (Q9CYA0), CREL2_RAT (Q4G063), POL_COYMV (P19199), SRCH_HUMAN (P23327), SRCH_RABIT (P16230), TYRO_BOVIN (Q8MIU0), TYRO_CANLF (P54834), TYRO_CHICK (P55024), TYRO_COTJA (Q08410), TYRO_FELCA (P55033), TYRO_GORGO (Q9BDE0), TYRO_HUMAN (P14679), TYRO_MOUSE (P11344), TYRO_ORYLA (P55025), TYRO_PELLE (Q0MVP0), TYRO_PELNI (Q04604), TYRO_PELSI (P55026), TYRP1_AMBME (P55027), TYRP1_BOVIN (Q8WN57), TYRP1_CARAU (P55028), TYRP1_CHICK (O57405), TYRP1_FELCA (Q2VPW6), TYRP1_HUMAN (P17643), TYRP1_MOUSE (P07147), TYRP2_BOVIN (Q95119), TYRP2_CHICK (O93505), TYRP2_HUMAN (P40126), TYRP2_MOUSE (P29812), TYRP2_PIG (Q4R1H1), WDR59_CHICK (Q5ZLG9), WDR59_HUMAN (Q6PJI9), WDR59_MOUSE (Q8C0M0)» more |
PDB [Detailed view] |
23 PDB
1KLO; 1NPE; 1TLE; 2Y38; 4AQS; 4AQT; 4OVE; 4PLM; 4PLN; 4PLO; 4URT; 4WNX; 5LF2; 6FKQ; 7LER; 7LRF; 7NDG; 7NE0; 7NE1; 8DMK; 8EDK; 8S9P; 8SNP » more |