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PROSITE entry PS01260


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PURL: https://purl.expasy.org/prosite/signature/PS01260

Direct ScanProsite submission
General information about the entry

Entry name [info] BH4_1
Accession [info] PS01260
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00829

Name and characterization of the entry

Description [info] Apoptosis regulator, Bcl-2 family BH4 motif signature.
Pattern [info]
[DS]-[NT]-R-[AE]-[LI]-V-x-[KD]-[FY]-[LIV]-[GHS]-Y-K-L-[SR]-Q-[RK]-G-
[HY]-x-[CW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 16 in 16 different sequences
Number of true positive hits 16 in 16 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 61.54 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
16 sequences

B2CL1_CHICK (Q07816), B2CL1_HUMAN (Q07817), B2CL1_MOUSE (Q64373), 
» more

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

B2L13_HUMAN (Q9BXK5), B2L13_MOUSE (P59017), BOKA_DANRE  (Q6DC66), 
» more

PDB
[Detailed view]
156 PDB

pdb_00001af3; pdb_00001bxl; pdb_00001g5j; pdb_00001g5m; pdb_00001gjh; pdb_00001lxl; pdb_00001maz; pdb_00001mk3; pdb_00001o0l; pdb_00001pq0; pdb_00001pq1; pdb_00001r2d;
» more