PROSITE entry PS01328

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PURL: https://purl.expasy.org/prosite/signature/PS01328

Direct ScanProsite submission

General information about the entry

Entry name [info]	4HBCOA_THIOESTERASE
Accession [info]	PS01328
Entry type [info]	PATTERN
Date [info]	01-JUL-1999 CREATED; 01-JUL-1999 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC01031
Associated ProRule [info]	PRU10041

Name and characterization of the entry

Description [info]	4-hydroxybenzoyl-CoA thioesterase family active site.
Pattern [info]	[QR]-[IV]-x(4)-[TC]-D-x(2)-G-[IV]-V-x-[HF]-x(2)-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.

Total number of hits	11 in 11 different sequences
Number of true positive hits	11 in 11 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	31
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	26.19 %

Comments [info]

Taxonomic range [info]	Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 5
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

11 sequences

4HBT_PSEUC  (P56653), DNCH_SYNY3  (Q55777), Y1494_AQUAE (O67466),

Y410_SYNY3  (Q55116), YBGC_ECO57  (P0A8Z5), YBGC_ECOL6  (P0A8Z4), 
YBGC_ECOLI  (P0A8Z3), YBGC_HAEIN  (P44679), YBGC_HELPJ  (Q9ZLX8), 
YBGC_HELPY  (P94842), YBGC_SHIFL  (P0A8Z6)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
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Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

31 sequences

DNCH_ACAM1  (B0CEN8), DNCH_CROS5  (B1WZN0), DNCH_GLOC7  (B7KDA3),

DNCH_MICAN  (B0JQL4), DNCH_NOSP7  (B2IZ83), DNCH_NOSS1  (Q8YU89), 
DNCH_PARMW  (Q7U3X6), DNCH_PICP2  (B1XL26), DNCH_PROM0  (A3PAP1), 
DNCH_PROM1  (A2C002), DNCH_PROM2  (A8G2H9), DNCH_PROM3  (A2CDA0), 
DNCH_PROM4  (A9BD34), DNCH_PROM5  (A2BUF0), DNCH_PROM9  (Q31D08), 
DNCH_PROMA  (Q7VE16), DNCH_PROMM  (Q7V4A7), DNCH_PROMP  (Q7V3A9), 
DNCH_PROMS  (A2BNW8), DNCH_PROMT  (Q46HJ9), DNCH_RIPO1  (B7JXS8), 
DNCH_SYNE7  (Q31ME5), DNCH_SYNP6  (Q5MZI3), DNCH_SYNPW  (A5GP76), 
DNCH_SYNR3  (A5GWA0), DNCH_SYNS3  (Q0I6T4), DNCH_SYNS9  (Q3AVZ5), 
DNCH_SYNSC  (Q3AGW5), DNCH_THEVB  (Q8DLK3), DNCH_TRIEI  (Q10XE8), 
DNCH_TRIV2  (Q3MG63)

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PDB
[Detailed view]

7 PDB

pdb_00001s5u; pdb_00002egi; pdb_00002egj; pdb_00002egr; pdb_00002pzh; pdb_00004k00; pdb_00005kl9