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PROSITE entry PS01351


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General information about the entry

Entry name [info] MAPK
Accession [info] PS01351
Entry type [info] PATTERN
Date [info] 01-DEC-2001 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01049

Name and characterization of the entry

Description [info] MAP kinase signature.
Pattern [info] 
F-x(10)-R-E-x(72,86)-R-D-x-K-x(9)-[CS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 205 in 205 different sequences
Number of true positive hits 203 in 203 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.02 %
Recall (true positives / (true positives + false negatives)) 98.07 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 203 sequences 

CPK1_CRYNB  (P0CP67), CPK1_CRYNJ  (P0CP66), ERK1_CANAL  (Q5A1D3), 

ERK1_CANAW  (C4YGK0), ERK1_DICDI  (P42525), ERK2_DICDI  (Q54QB1), 
ERK7_DROME  (Q9W354), ERKA_DROME  (P40417), FUS3_YEAST  (P16892), 
HOG1A_WALI9 (A3EZ55), HOG1B_WALI9 (M1T7M3), HOG1_ALTBR  (Q52PH6), 
HOG1_ASPCL  (A1CPG7), HOG1_ASPFU  (Q4WSF6), HOG1_ASPGL  (Q38HL5), 
HOG1_ASPNC  (A2QRF6), HOG1_ASPTN  (Q0D0P5), HOG1_BEABA  (Q6PWX2), 
HOG1_BLAAD  (Q702W0), HOG1_BLUGR  (Q8TGA9), HOG1_BOTFB  (A1IVT7), 
HOG1_CANAL  (Q92207), HOG1_CANGA  (Q6FIU2), HOG1_CHAGB  (Q2H332), 
HOG1_COCHE  (Q4W6D3), HOG1_COCIM  (Q1DUU8), HOG1_COCMI  (Q2WFL5), 
HOG1_COLOR  (Q75Q66), HOG1_CRYNB  (P0CP69), HOG1_CRYNH  (Q56R42), 
HOG1_CRYNJ  (P0CP68), HOG1_CRYPA  (Q875L0), HOG1_DEBHA  (Q9UV50), 
HOG1_EMENI  (Q9P419), HOG1_EREGS  (Q750A9), HOG1_EXSTU  (Q5I6M2), 
HOG1_FUSCU  (Q4PNJ1), HOG1_GIBIN  (Q4PKS0), HOG1_GIBZE  (P0C431), 
HOG1_HORWE  (Q8NJT7), HOG1_HYPAT  (Q6XKY3), HOG1_KLULA  (Q6CJA8), 
HOG1_NEOFI  (A1D2C9), HOG1_NEUCR  (Q96TL5), HOG1_PHANO  (Q0U4L8), 
HOG1_PICST  (A3LN91), HOG1_PYRO7  (Q9UV51), HOG1_SCHPO  (Q09892), 
HOG1_TORDE  (Q1L5Z8), HOG1_TRIHA  (Q2WGK3), HOG1_USTMA  (Q4PC06), 
HOG1_YARLI  (Q6C4M9), HOG1_YEAST  (P32485), HOG1_ZYGRC  (O93982), 
HOG1_ZYGRO  (O59854), HOG1_ZYMTI  (Q1KTF2), HOG2_ZYGRO  (O59853), 
JNK1_ANCCA  (Q9U6D2), JNK1_CAEEL  (Q8WQG9), JNK_DROME   (P92208), 
JNK_SUBDO   (Q966Y3), KGB1_CAEEL  (O44408), KSS1_YEAST  (P14681), 
MAPK1_PNECA (O94737), MAPK2_PNECA (O42781), MAPK_FUSVN  (Q00859), 
MK01_BOVIN  (P46196), MK01_HUMAN  (P28482), MK01_MOUSE  (P63085), 
MK01_RAT(P63086), MK01_XENLA  (P26696), MK03_HUMAN  (P27361), 
MK03_MOUSE  (Q63844), MK03_RAT(P21708), MK07_BOVIN  (A5PKJ4), 
MK07_HUMAN  (Q13164), MK07_MOUSE  (Q9WVS8), MK07_RAT(P0C865), 
MK08A_CYPCA (Q90327), MK08B_CYPCA (O42099), MK08_DANRE  (Q9DGD9), 
MK08_HUMAN  (P45983), MK08_MOUSE  (Q91Y86), MK08_RAT(P49185), 
MK08_XENLA  (Q8QHK8), MK09_CHICK  (P79996), MK09_HUMAN  (P45984), 
MK09_MOUSE  (Q9WTU6), MK09_RAT(P49186), MK10_HUMAN  (P53779), 
MK10_MOUSE  (Q61831), MK10_RAT(P49187), MK11_HUMAN  (Q15759), 
MK11_MOUSE  (Q9WUI1), MK12_DANRE  (O42376), MK12_HUMAN  (P53778), 
MK12_MOUSE  (O08911), MK12_RAT(Q63538), MK13_BOVIN  (Q3T0N5), 
MK13_HUMAN  (O15264), MK13_MOUSE  (Q9Z1B7), MK13_PANTR  (Q9N272), 
MK13_RAT(Q9WTY9), MK14A_CYPCA (Q90336), MK14A_DANRE (Q9DGE2), 
MK14B_CYPCA (Q9I958), MK14B_DANRE (Q9DGE1), MK14C_DROME (P83100), 
MK14_CANLF  (O02812), MK14_HUMAN  (Q16539), MK14_MOUSE  (P47811), 
MK14_PANTR  (Q95NE7), MK14_RAT(P70618), MK14_XENLA  (P47812), 
MK15_CAEEL  (Q11179), MK15_HUMAN  (Q8TD08), MK15_MOUSE  (Q80Y86), 
MK15_RAT(Q9Z2A6), MK15_XENLA  (Q501Q9), MK1_CAPAN   (Q9LKZ2), 
MK2_CAPAN   (Q9LKZ1), MK38A_DROME (O62618), MK38B_DROME (O61443), 
MKC1_CANAL  (Q5AAG6), MKC1_CANAX  (P43068), MMK1_MEDSA  (Q07176), 
MMK2_MEDSA  (Q40353), MPK10_ARATH (Q9M1Z5), MPK10_ORYSJ (Q5ZCI1), 
MPK11_ARATH (Q9LMM5), MPK11_ORYSJ (Q5VN19), MPK12_ORYSJ (Q5Z9J0), 
MPK13_ARATH (Q9LQQ9), MPK13_ORYSI (A2X0M1), MPK13_ORYSJ (Q0E459), 
MPK14_ARATH (O23236), MPK14_ORYSJ (Q75KK8), MPK15_ARATH (Q9C9U4), 
MPK15_ORYSJ (Q53N72), MPK16_ARATH (Q8W4J2), MPK16_ORYSJ (Q5VP69), 
MPK17_ARATH (Q84M93), MPK17_ORYSJ (Q6L5F7), MPK18_ARATH (Q9C5C0), 
MPK19_ARATH (Q9LUC3), MPK1_CAEEL  (P39745), MPK1_ORYSJ  (Q84UI5), 
MPK20_ARATH (Q9SJG9), MPK2_ARATH  (Q39022), MPK3_ARATH  (Q39023), 
MPK3_ORYSJ  (Q6Z437), MPK4A_PHYPA (A9T142), MPK4B_PHYPA (A9S9Q8), 
MPK4_ARATH  (Q39024), MPK4_LEIME  (Q9GRU1), MPK4_ORYSJ  (Q5Z859), 
MPK5_ARATH  (Q39025), MPK5_ORYSI  (A2XFC8), MPK5_ORYSJ  (Q10N20), 
MPK6_ARATH  (Q39026), MPK6_ORYSJ  (Q336X9), MPK7_ARATH  (Q39027), 
MPK7_ORYSJ  (Q67C40), MPK8_ARATH  (Q9LM33), MPK8_ORYSJ  (Q5SN53), 
MPK9_ARATH  (Q9LV37), MPK9_ORYSJ  (Q6L5D4), MPKA_ASPFC  (B0Y4X4), 
MPKA_ASPFU  (Q4WQR3), MPKB_ASPFC  (B0Y8W7), MPKC_ASPCL  (A1CAF0), 
MPKC_ASPFC  (B0Y462), MPKC_ASPFU  (Q4WUN7), MPKC_ASPNC  (A2QN07), 
MPKC_ASPOR  (Q2U469), MPKC_ASPTN  (Q0CIC7), MPKC_EMENI  (Q9HG11), 
MPKC_NEOFI  (A1DES4), MPK_PEA (Q06060), MPK_PETHY   (Q40884), 
MPS1_PYRO7  (G4N374), MPS1_PYROR  (O13352), NLK2_XENLA  (Q8QGV6), 
NLK2_XENTR  (B1H3E1), NLK_BOVIN   (E1BMN8), NLK_CAEEL   (Q9U9Y8), 
NLK_CANLF   (E2QWQ2), NLK_HUMAN   (Q9UBE8), NLK_MOUSE   (O54949), 
NLK_RAT (D3ZSZ3), NTF3_TOBAC  (Q40517), NTF4_TOBAC  (Q40532), 
NTF6_TOBAC  (Q40531), PMK1_CAEEL  (Q17446), PMK1_PYRO7  (G4N0Z0), 
PMK1_PYROR  (Q92246), PMK2_CAEEL  (Q8MXI4), PMK3_CAEEL  (O44514), 
SAKA_ASPFC  (B0XR80), SIPK_TOBAC  (A0A1S3Z5Y0), SLT2_YEAST  (Q00772), 
SPK1_SCHPO  (P27638), SPM1_SCHPO  (Q92398)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

MPK12_ARATH (Q8GYQ5), MPK1_ARATH  (Q39021), MPK2_ORYSJ  (Q5J4W4), 

SMK1_YEAST  (P41808)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

IDM1_ARATH  (F4IXE7), MRH4_PYRO7  (A4QTC6)


				
	

	

		PDB
[Detailed view]		
		
			706 PDB
			


			1A9U; 1BL6; 1BL7; 1BMK; 1CM8; 1DI9; 1GOL; 1IAN; 1JNK; 1KV1; 1KV2; 1LEW; 
			
				1LEZ; 1M7Q; 1OUK; 1OUY; 1OVE; 1OZ1; 1PME; 1PMN; 1PMU; 1PMV; 1R39; 1R3C; 
				1TVO; 1UKH; 1UKI; 1W7H; 1W82; 1W83; 1W84; 1WBN; 1WBO; 1WBS; 1WBT; 1WBV; 
				1WBW; 1WFC; 1WZY; 1YQJ; 1YW2; 1YWR; 1ZYJ; 1ZZ2; 1ZZL; 2B1P; 2B9F; 2B9H; 
				2B9I; 2B9J; 2BAJ; 2BAK; 2BAL; 2BAQ; 2ERK; 2EWA; 2EXC; 2F49; 2F9G; 2FA2; 
				2FSL; 2FSM; 2FSO; 2FST; 2FYS; 2G01; 2GFS; 2GHL; 2GHM; 2GMX; 2GPH; 2GTM; 
				2GTN; 2H96; 2I0H; 2LGC; 2NO3; 2NPQ; 2O0U; 2O2U; 2OJG; 2OJI; 2OJJ; 2OK1; 
				2OKR; 2ONL; 2OZA; 2P33; 2PUU; 2QD9; 2R9S; 2RG5; 2RG6; 2WAJ; 2XRW; 2XS0; 
				2Y8O; 2Y9Q; 2YIS; 2YIW; 2YIX; 2Z7L; 2ZAZ; 2ZB0; 2ZB1; 2ZDT; 2ZDU; 2ZOQ; 
				3BV2; 3BV3; 3BX5; 3C5U; 3C9W; 3CGF; 3CGO; 3COI; 3CTQ; 3D7Z; 3D83; 3DA6; 
				3DS6; 3DT1; 3E7O; 3E92; 3E93; 3ELJ; 3ERK; 3FC1; 3FI2; 3FI3; 3FI4; 3FKL; 
				3FKN; 3FKO; 3FL4; 3FLN; 3FLQ; 3FLS; 3FLW; 3FLY; 3FLZ; 3FMH; 3FMJ; 3FMK; 
				3FML; 3FMM; 3FMN; 3FSF; 3FSK; 3FV8; 3G90; 3G9L; 3G9N; 3GC7; 3GC8; 3GC9; 
				3GCP; 3GCQ; 3GCS; 3GCU; 3GCV; 3GFE; 3GI3; 3GP0; 3HA8; 3HEC; 3HEG; 3HL7; 
				3HLL; 3HP2; 3HP5; 3HRB; 3HUB; 3HUC; 3HV3; 3HV4; 3HV5; 3HV6; 3HV7; 3HVC; 
				3I5Z; 3I60; 3IPH; 3ITZ; 3IW5; 3IW6; 3IW7; 3IW8; 3K3I; 3K3J; 3KF7; 3KQ7; 
				3KVX; 3L8S; 3L8X; 3LFA; 3LFB; 3LFC; 3LFD; 3LFE; 3LFF; 3LHJ; 3MGY; 3MH0; 
				3MH1; 3MH2; 3MH3; 3MPA; 3MPT; 3MVL; 3MVM; 3MW1; 3NEW; 3NNU; 3NNV; 3NNW; 
				3NNX; 3NPC; 3NWW; 3O17; 3O2M; 3O71; 3O8P; 3O8T; 3O8U; 3OBG; 3OBJ; 3OC1; 
				3OCG; 3OD6; 3ODY; 3ODZ; 3OEF; 3OXI; 3OY1; 3P4K; 3P5K; 3P78; 3P79; 3P7A; 
				3P7B; 3P7C; 3PG3; 3PTG; 3PY3; 3PZE; 3QUD; 3QUE; 3QYW; 3QYZ; 3R63; 3RIN; 
				3ROC; 3RTP; 3S3I; 3S4Q; 3SA0; 3TEI; 3TG1; 3TTI; 3TTJ; 3U8W; 3UVP; 3UVQ; 
				3UVR; 3V3V; 3V6R; 3V6S; 3VUD; 3VUG; 3W55; 3ZS5; 3ZSG; 3ZSH; 3ZSI; 3ZU7; 
				3ZUV; 3ZYA; 4A9Y; 4AA0; 4AA4; 4AA5; 4AAC; 4AWI; 4B99; 4DLI; 4DLJ; 4E5A; 
				4E5B; 4E6A; 4E6C; 4E73; 4E8A; 4EH2; 4EH3; 4EH4; 4EH5; 4EH6; 4EH7; 4EH8; 
				4EH9; 4EHV; 4ERK; 4EWQ; 4EYJ; 4EYM; 4F9W; 4F9Y; 4FA2; 4FMQ; 4FUX; 4FUY; 
				4FV0; 4FV1; 4FV2; 4FV3; 4FV4; 4FV5; 4FV6; 4FV7; 4FV8; 4FV9; 4G1W; 4G6N; 
				4G6O; 4GEO; 4GSB; 4GT3; 4GVA; 4H36; 4H39; 4H3B; 4H3P; 4H3Q; 4HYS; 4HYU; 
				4I5H; 4IC7; 4IC8; 4IZ5; 4IZ7; 4IZA; 4IZY; 4KA3; 4KIN; 4KIP; 4KIQ; 4KKE; 
				4KKG; 4KKH; 4L7F; 4L8M; 4LOO; 4LOP; 4LOQ; 4MYG; 4N0S; 4N4S; 4NIF; 4O6E; 
				4QP1; 4QP2; 4QP3; 4QP4; 4QP6; 4QP7; 4QP8; 4QP9; 4QPA; 4QTA; 4QTB; 4QTD; 
				4QTE; 4QYY; 4R3C; 4S2Z; 4S30; 4S31; 4S32; 4S33; 4S34; 4TYH; 4U79; 4UX9; 
				4W4V; 4W4W; 4W4X; 4W4Y; 4WHZ; 4X21; 4XJ0; 4XNE; 4XOY; 4XOZ; 4XP0; 4XP2; 
				4XP3; 4XRJ; 4XRL; 4Y46; 4Y5H; 4YNO; 4YR8; 4Z9L; 4ZSG; 4ZSJ; 4ZSL; 4ZTH; 
				4ZXT; 4ZZM; 4ZZN; 4ZZO; 5AWM; 5AX3; 5BUE; 5BUI; 5BUJ; 5BVD; 5BVE; 5BVF; 
				5BYY; 5BYZ; 5CI6; 5EKN; 5EKO; 5ETA; 5ETC; 5ETF; 5ETI; 5HD4; 5HD7; 5K4I; 
				5KE0; 5LAR; 5LCJ; 5LCK; 5LW1; 5ML5; 5MTX; 5MTY; 5MZ3; 5N63; 5N64; 5N65; 
				5N66; 5N67; 5N68; 5NGU; 5NHF; 5NHH; 5NHJ; 5NHL; 5NHO; 5NHP; 5NHV; 5NZZ; 
				5O7I; 5O8U; 5O8V; 5O90; 5OMG; 5OMH; 5R8U; 5R8V; 5R8W; 5R8X; 5R8Y; 5R8Z; 
				5R90; 5R91; 5R92; 5R93; 5R94; 5R95; 5R96; 5R97; 5R98; 5R99; 5R9A; 5R9B; 
				5R9C; 5R9D; 5R9E; 5R9F; 5R9G; 5R9H; 5R9I; 5R9J; 5R9K; 5R9L; 5R9M; 5R9N; 
				5R9O; 5R9P; 5R9Q; 5R9R; 5R9S; 5R9T; 5R9U; 5R9V; 5R9W; 5R9X; 5R9Y; 5R9Z; 
				5RA0; 5RA1; 5RA2; 5RA3; 5RA4; 5RA5; 5RA6; 5RA7; 5RA8; 5RA9; 5TBE; 5TCO; 
				5U6I; 5UMO; 5UOJ; 5V60; 5V61; 5V62; 5WJJ; 5WP1; 5XYX; 5XYY; 5Z33; 6ANL; 
				6CPW; 6D5Y; 6DCG; 6DMG; 6DTL; 6EKD; 6EMH; 6EQ9; 6F5E; 6FI3; 6FI6; 6FJ0; 
				6FJB; 6FJZ; 6FLE; 6FLV; 6FMA; 6FN5; 6FQ7; 6FR1; 6FRP; 6FXV; 6G54; 6G8X; 
				6G91; 6G92; 6G93; 6G97; 6G9A; 6G9D; 6G9H; 6G9J; 6G9K; 6G9M; 6G9N; 6GDM; 
				6GDQ; 6GE0; 6GES; 6GJB; 6GJD; 6HKM; 6HKN; 6HWT; 6HWU; 6HWV; 6M95; 6M9L; 
				6NBS; 6OHD; 6OPG; 6OPH; 6OPI; 6OPK; 6OT6; 6OTS; 6Q7K; 6Q7S; 6Q7T; 6QA1; 
				6QA3; 6QA4; 6QAG; 6QAH; 6QAL; 6QAQ; 6QAW; 6QDZ; 6QE1; 6QYX; 6RFO; 6RFP; 
				6RQ4; 6SFI; 6SFJ; 6SFK; 6SFO; 6SLG; 6SO1; 6SO2; 6SO4; 6SOD; 6SOI; 6SOT; 
				6SOU; 6SOV; 6SP9; 6SPL; 6TCA; 6UNA; 6Y4T; 6Y4U; 6Y4V; 6Y4W; 6Y4X; 6Y6V; 
				6Y7W; 6Y7X; 6Y7Y; 6Y7Z; 6Y80; 6Y81; 6Y82; 6Y85; 6Y8H; 6YCU; 6YCW; 6YJC; 
				6YK7; 6ZQS; 6ZR5; 6ZWP; 6ZWR; 7AUV; 7BDO; 7BDQ; 7BE4; 7BE5; 7CGA; 7CML; 
				7E73; 7E75; 7KSI; 7KSJ; 7KSK; 7N8T; 7NQQ; 7NQW; 7NR3; 7NR5; 7NR8; 7NR9; 
				7OPM; 7ORE; 7ORF; 7PUS; 7PVU; 7S1N; 7UGB; 7W5C; 7W5O; 7X4U; 7XC1; 7YL1; 
				7Z6I; 7Z9T; 8A8M; 8ACM; 8ACO; 8AO2; 8AO3; 8AO4; 8AO5; 8AO6; 8AO7; 8AO8; 
				8AO9; 8AOA; 8AOB; 8AOC; 8AOD; 8AOE; 8AOF; 8AOG; 8AOH; 8AOI; 8AOJ; 8BZP; 
				8EFJ; 8ELC; 8ENJ; 8H59; 8U8J; 8U8K; 8WGF; 8X23; 8X5M; 8YGW
			
			

			» more