PROSITE entry PS01353

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS01353
Entry name [info]	HEMATOPO_REC_L_F2
Accession [info]	PS01353
Entry type [info]	PATTERN
Date [info]	01-DEC-2001 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC01051

Name and characterization of the entry

Description [info]	Long hematopoietin receptor, gp130 family signature.
Pattern [info]	N-x(4)-S-x(28,35)-[LVIM]-x-W-x(0,3)-P-x(5,9)-[YF]-x(1,2)-[VILM]- x-W.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	26 in 26 different sequences
Number of true positive hits	22 in 22 different sequences
Number of 'unknown' hits	0
Number of false positive hits	4 in 4 different sequences
Number of false negative sequences	2
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	84.62 %
Recall (true positives / (true positives + false negatives))	91.67 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	22 sequences CSF3R_HUMAN (Q99062), CSF3R_MOUSE (P40223), I12R1_HUMAN (P42701), I12R2_BOVIN (Q9BEG2), I12R2_HUMAN (Q99665), I12R2_MOUSE (P97378), I12R2_PIG (Q8MJS1), IL6RB_HUMAN (P40189), IL6RB_MOUSE (Q00560), IL6RB_RAT (P40190), LEPR_HUMAN (P48357), LEPR_MACMU (Q9MYL0), LEPR_MOUSE (P48356), LEPR_PIG(O02671), LEPR_RAT(Q62959), LIFR_CANLF (Q5XNR9), LIFR_HUMAN (P42702), LIFR_MOUSE (P42703), LIFR_RAT(O70535), OSMR_HUMAN (Q99650), OSMR_MOUSE (O70458), OSMR_RAT(Q65Z14) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	2 sequences I12R1_MOUSE (Q60837), I27RA_HUMAN (Q6UWB1)
UniProtKB/Swiss-Prot False positive sequences	4 sequences FND3B_HUMAN (Q53EP0), FND3B_MOUSE (Q6NWW9), GET1_CRYNB (P0CS59), GET1_CRYNJ (P0CS58) » more
PDB [Detailed view]	36 PDB 3L5H; 3L5I; 3L5J; 8AV2; 8AVB; 8AVC; 8AVD; 8AVE; 8AVF; 8AVO; 8B7Q; 8C7M; 8D6A; 8D74; 8D7R; 8D82; 8D85; 8DH8; 8DH9; 8DHA; 8DPT; 8ODX; 8ODZ; 8OE0; 8OE4; 8PB1; 8QY4; 8QY5; 8QY6; 8V29; 8V2A; 8V2B; 8V2C; 8X80; 8X81; 8X85 » more