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PROSITE entry PS01353


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PURL: https://purl.expasy.org/prosite/signature/PS01353

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General information about the entry

Entry name [info] HEMATOPO_REC_L_F2
Accession [info] PS01353
Entry type [info] PATTERN
Date [info] 01-DEC-2001 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01051

Name and characterization of the entry

Description [info] Long hematopoietin receptor, gp130 family signature.
Pattern [info] 
N-x(4)-S-x(28,35)-[LVIM]-x-W-x(0,3)-P-x(5,9)-[YF]-x(1,2)-[VILM]-
x-W.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 26 in 26 different sequences
Number of true positive hits 22 in 22 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 84.62 %
Recall (true positives / (true positives + false negatives)) 91.67 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 22 sequences 

CSF3R_HUMAN (Q99062), CSF3R_MOUSE (P40223), I12R1_HUMAN (P42701), 

I12R2_BOVIN (Q9BEG2), I12R2_HUMAN (Q99665), I12R2_MOUSE (P97378), 
I12R2_PIG   (Q8MJS1), IL6RB_HUMAN (P40189), IL6RB_MOUSE (Q00560), 
IL6RB_RAT   (P40190), LEPR_HUMAN  (P48357), LEPR_MACMU  (Q9MYL0), 
LEPR_MOUSE  (P48356), LEPR_PIG(O02671), LEPR_RAT(Q62959), 
LIFR_CANLF  (Q5XNR9), LIFR_HUMAN  (P42702), LIFR_MOUSE  (P42703), 
LIFR_RAT(O70535), OSMR_HUMAN  (Q99650), OSMR_MOUSE  (O70458), 
OSMR_RAT(Q65Z14)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

I12R1_MOUSE (Q60837), I27RA_HUMAN (Q6UWB1)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			4 sequences
			


			
FND3B_HUMAN (Q53EP0), FND3B_MOUSE (Q6NWW9), GET1_CRYNB  (P0CS59), 

			
GET1_CRYNJ  (P0CS58)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			36 PDB
			


			pdb_00003l5h; pdb_00003l5i; pdb_00003l5j; pdb_00008av2; pdb_00008avb; pdb_00008avc; pdb_00008avd; pdb_00008ave; pdb_00008avf; pdb_00008avo; pdb_00008b7q; pdb_00008c7m; 
			
				pdb_00008d6a; pdb_00008d74; pdb_00008d7r; pdb_00008d82; pdb_00008d85; pdb_00008dh8; pdb_00008dh9; pdb_00008dha; pdb_00008dpt; pdb_00008odx; pdb_00008odz; pdb_00008oe0; 
				pdb_00008oe4; pdb_00008pb1; pdb_00008qy4; pdb_00008qy5; pdb_00008qy6; pdb_00008v29; pdb_00008v2a; pdb_00008v2b; pdb_00008v2c; pdb_00008x80; pdb_00008x81; pdb_00008x85
			
			

			» more