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PROSITE entry PS50020


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50020
Entry name [info] WW_DOMAIN_2
Accession [info] PS50020
Entry type [info] MATRIX
Date [info] 01-NOV-1995 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50020
Associated ProRule [info] PRU00224

Name and characterization of the entry

Description [info] WW/rsp5/WWP domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=34;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=31;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.2776000; R2=0.0197000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1518.2681885; R2=1.0788643; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=418; H_SCORE=1969; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=316; H_SCORE=1859; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 392 in 227 different sequences
Number of true positive hits 392 in 227 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 17
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.84 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 4
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] WW
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
227 sequences

APBB1_HUMAN (O00213), APBB1_MOUSE (Q9QXJ1), APBB1_RAT   (P46933), 
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UniProtKB/Swiss-Prot
False negative sequences
17 sequences

CFL1_ARATH  (Q5HZ54), CFL1_ORYSI  (B8AIM8), CFL1_ORYSJ  (Q0E0W7), 
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PDB
[Detailed view]
238 PDB

1E0L; 1E0N; 1EG3; 1EG4; 1F8A; 1I5H; 1I6C; 1I8G; 1I8H; 1JMQ; 1K5R; 1K9Q;
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