PROSITE entry PS50108
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General information about the entry
| Entry name [info] | CRIB |
| Accession [info] | PS50108 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50108 |
| Associated ProRule [info] | PRU00057 |
Name and characterization of the entry
| Description [info] | CRIB domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=14; /DISJOINT: DEFINITION=PROTECT; N1=2; N2=13; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-0.2255000; R2=0.0176662; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=419.6926270; R2=0.3792415; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=421; H_SCORE=579; N_SCORE=7.2; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=381; H_SCORE=564; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='I'; M= -7,-30,-25,-37,-30, 0,-37,-30, 45,-27, 17, 17,-23,-23,-23,-27,-17, -7, 35,-23, -3,-30; /M: SY='G'; M= 6, -4,-18, -4, -8,-24, 27,-14,-28,-14,-30,-20, 6,-14, -8,-14, 25, 5,-18,-32,-24, -8; /M: SY='S'; M= 4, -4,-19, -8, -4,-14, -9, -6,-13, -9,-13, -9, 1, -9, -4,-10, 6, 5,-11,-26,-11, -5; /M: SY='P'; M= -9,-19,-39,-10, 0,-30,-19,-20,-20,-10,-30,-20,-19, 87,-10,-20, -8, -9,-29,-30,-30,-10; /M: SY='T'; M= -4,-11,-15,-17,-13, 8,-19,-15, -5,-15, -4, -3, -6,-17,-12,-12, 7, 18, -1,-21, -1,-11; /I: I=-6; MI=0; MD=-32; IM=0; DM=-32; /M: SY='N'; M=-12, 39,-23, 31, 4,-26, 2, 4,-27, -2,-30,-23, 43,-17, -2, -4, 7, -4,-30,-38,-21, 1; /M: SY='F'; M=-13,-29,-19,-35,-27, 50,-29,-21, 6,-26, 9, 2,-22,-24,-34,-20,-17, -8, 10, -2, 18,-28; /M: SY='K'; M= -9, -1,-26, -1, 12,-25,-20, -7,-20, 22,-20, -8, -1,-12, 11, 18, -4, -5,-14,-24,-12, 11; /M: SY='H'; M=-20, -1,-30, -1, 0,-19,-20, 91,-29, -7,-20, -1, 9,-20, 10, 5,-10,-19,-29,-28, 19, 0; /M: SY='T'; M= -7, -6,-21, -9, -5,-13,-23, -9, -2, -6, -4, -2, -5,-17, -4, -4, -3, 4, 1,-27, -8, -6; /M: SY='V'; M= 3,-20,-14,-25,-21, -2,-17,-19, 11,-18, 1, 5,-16,-21,-18,-19, -3, 0, 17,-23, -6,-20; /M: SY='H'; M=-20, 0,-30, 0, 0,-20,-20,100,-30,-10,-20, 0, 10,-20, 10, 0,-10,-20,-30,-30, 20, 0; /M: SY='V'; M= -2,-27,-15,-31,-28, -1,-30,-28, 31,-21, 11, 13,-25,-26,-25,-21,-11, 0, 40,-27, -7,-27; /M: SY='G'; M= -1, -2,-27, -3,-15,-29, 54,-15,-36,-16,-30,-20, 8,-19,-16,-17, 4,-14,-28,-24,-28,-15; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 127 in 127 different sequences |
| Number of true positive hits | 127 in 127 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 4 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.95 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | CRIB |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
127 sequences
ACKL_DROME (Q9I7F7 ), ARK1_CAEEL (G5EBZ8 ), BORG1_BOVIN (Q08DN6 ), BORG1_HUMAN (O14613 ), BORG1_MOUSE (Q8JZX9 ), BORG1_RAT (Q5PQP4 ), BORG2_HUMAN (Q9UKI2 ), BORG2_MOUSE (Q9CQC5 ), BORG3_HUMAN (Q6NZY7 ), BORG3_MOUSE (Q9Z0X0 ), BORG4_HUMAN (Q9H3Q1 ), BORG4_MOUSE (Q9JM96 ), BORG5_BOVIN (Q17QW1 ), BORG5_HUMAN (Q00587 ), BORG5_MOUSE (Q91W92 ), BORG5_RAT (A1A5P0 ), C42ES_DROME (Q9VNE7 ), C42S1_BOVIN (Q5BIS3 ), C42S1_CHICK (Q5ZKB1 ), C42S1_DANRE (Q6TEL3 ), C42S1_HUMAN (Q9NRR8 ), C42S1_MOUSE (Q8BHL7 ), C42S1_PONAB (Q5RDD6 ), C42S1_RAT (Q5BJM7 ), C42S1_XENTR (Q5BKH3 ), C42S2_BOVIN (A6QLJ4 ), C42S2_DANRE (A9JR56 ), C42S2_HUMAN (Q9NRR3 ), C42S2_MOUSE (Q8BGH7 ), C42S2_PONAB (Q5R4F8 ), C42S2_RAT (A1L1K4 ), C4S1A_XENLA (Q66KZ1 ), C4S1B_XENLA (Q6GPV4 ), C4S2A_XENLA (Q5FVD7 ), C4S2A_XENTR (Q28EW5 ), C4S2B_XENLA (Q6AX78 ), C4S2B_XENTR (Q28GG3 ), C4S2C_XENLA (Q4V853 ), CLA4_ASHGO (Q9HFW2 ), CLA4_CANAL (Q5APR8 ), CLA4_CANAX (O14427 ), CLA4_YEAST (P48562 ), GEK_DROME (Q9W1B0 ), GIC1_YEAST (P38785 ), GIC2_YEAST (Q06648 ), MAX2_CAEEL (G5EGQ3 ), MRCKA_HUMAN (Q5VT25 ), MRCKA_MOUSE (Q3UU96 ), MRCKA_RAT (O54874 ), MRCKB_HUMAN (Q9Y5S2 ), MRCKB_MOUSE (Q7TT50 ), MRCKB_RAT (Q7TT49 ), MRCKG_HUMAN (Q6DT37 ), MRCKG_MOUSE (Q80UW5 ), MRCK_CAEEL (O01583 ), PAK1_BOVIN (Q08E52 ), PAK1_HUMAN (Q13153 ), PAK1_MOUSE (O88643 ), PAK1_RAT (P35465 ), PAK2_HUMAN (Q13177 ), PAK2_MOUSE (Q8CIN4 ), PAK2_RABIT (Q29502 ), PAK2_RAT (Q64303 ), PAK3_HUMAN (O75914 ), PAK3_MOUSE (Q61036 ), PAK3_PANTR (Q7YQL4 ), PAK3_PONPY (Q7YQL3 ), PAK3_RAT (Q62829 ), PAK3_XENLA (Q8AXB4 ), PAK4_HUMAN (O96013 ), PAK4_MOUSE (Q8BTW9 ), PAK5_HUMAN (Q9P286 ), PAK5_MOUSE (Q8C015 ), PAK5_RAT (D4A280 ), PAK6_HUMAN (Q9NQU5 ), PAK6_MOUSE (Q3ULB5 ), PAK6_PONAB (Q5R8Z4 ), PAKA_DICDI (Q55D99 ), PAKB_DICDI (Q869N2 ), PAKC_DICDI (Q55GV3 ), PAKD_DICDI (Q55DD4 ), PAKG_DICDI (Q54RV3 ), PAKM_DROME (Q9VXE5 ), PAK_DROME (Q9VI13 ), PK1_CAEEL (Q17850 ), PK2_CAEEL (G5EFU0 ), RGAP1_ARATH (Q9FMR1 ), RGAP2_ARATH (F4JI46 ), RGAP4_ARATH (Q9CAX8 ), RGAP5_ARATH (Q6NKT5 ), RIC10_ARATH (Q9M0Y9 ), RIC11_ARATH (Q0WL69 ), RIC1_ARATH (F4IVV0 ), RIC2_ARATH (Q8GYU0 ), RIC3_ARATH (F4I5N6 ), RIC4_ARATH (Q9FFD5 ), RIC5_ARATH (F4J424 ), RIC6_ARATH (Q1PF35 ), RIC7_ARATH (Q1G3K8 ), RIC8_ARATH (Q9ZWB8 ), RIC9_ARATH (Q1G3Y0 ), SHK2_SCHPO (Q10056 ), SKM1_YEAST (Q12469 ), STE20_ASHGO (Q75DK7 ), STE20_ASPFU (Q4WHP3 ), STE20_ASPOR (Q2ULU3 ), STE20_CANAL (P0CY24 ), STE20_CANAW (C4YRB7 ), STE20_CANAX (P0CY23 ), STE20_CANGA (Q6FN53 ), STE20_DEBHA (Q6BNF3 ), STE20_EMENI (Q5BBL3 ), STE20_KLULA (Q6CVA2 ), STE20_MAGO7 (Q7Z8E9 ), STE20_NEUCR (Q7RZD3 ), STE20_SCHPO (P50527 ), STE20_TALMA (Q2VWQ3 ), STE20_USTMA (Q4P5N0 ), STE20_YARLI (Q6C3D7 ), STE20_YEAST (Q03497 ), WASL_BOVIN (Q95107 ), WASL_HUMAN (O00401 ), WASL_MOUSE (Q91YD9 ), WASL_RAT (O08816 ), WASP_HUMAN (P42768 ), WASP_MOUSE (P70315 ), YN03_CAEEL (Q03607 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
4 sequences
ACK1_HUMAN (Q07912 ), ACK1_MOUSE (O54967 ), PAKF_DICDI (Q869T7 ), RGAP3_ARATH (Q8GYY5 )» more |
| PDB [Detailed view] |
11 PDB
1CEE; 1E0A; 1EES; 1F3M; 2ODB; 2OV2; 2QME; 4FIE; 5UPK; 5UPL; 6UHC |