PROSITE entry PS50171
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS50171 |
| Entry name [info] | ZF_MATRIN |
| Accession [info] | PS50171 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50171 |
| Associated ProRule [info] | PRU00130 |
Name and characterization of the entry
| Description [info] | Zinc finger matrin-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=33; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=30; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.5940000; R2=0.0123623; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1566.0997314; R2=1.6650832; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=559; H_SCORE=2497; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=397; H_SCORE=2227; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-8; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='Y'; M=-18,-22,-27,-26,-21, 37,-30, -1, 2,-12, 2, 1,-18,-27,-18,-11,-19,-10, -4, 13, 46,-21; /M: SY='Y'; M=-18,-12,-27,-15,-10, 25,-25, 5, -8, -8, -5, -5, -7,-25,-11, -2,-14, -9,-13, 7, 38,-12; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='E'; M=-13, 11,-32, 22, 25,-33,-17, -7,-30, 12,-27,-20, 1, 15, 6, 0, -4,-10,-28,-30,-20, 15; /M: SY='Y'; M=-14,-27,-27,-31,-24, 20,-33,-10, 21,-23, 19, 11,-22,-27,-18,-20,-22,-10, 9, 0, 30,-24; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='S'; M= -2, 3,-20, 6, 0,-22, -1, -1,-23, -5,-21,-15, 5,-14, -2, -7, 13, 1,-16,-33,-15, -2; /M: SY='T'; M= -7, -2, -2,-10,-11,-10,-18,-12,-10,-11, -3, -7, 4,-21,-10, -5, 1, 10, -8,-32,-13,-11; /M: SY='W'; M=-18,-26,-30,-30,-22, 34,-27,-10, -5,-14, 1, -3,-23,-28,-21,-12,-24,-14,-10, 38, 37,-20; /M: SY='Y'; M=-12,-21,-22,-24,-20, 14,-29, 0, 9,-20, 13, 7,-18,-26,-16,-16,-16, -3, 5, -8, 23,-20; /M: SY='T'; M= 0, -1,-17, -8, -8, -7,-15, -6,-12, -3,-14,-10, 2,-15, -6, -6, 9, 17, -8,-17, 6, -8; /M: SY='N'; M=-12, 16,-25, 11, -1,-22, -1, 22,-27, -3,-25,-14, 24,-18, 0, 3, 2, -5,-26,-32,-10, -2; /M: SY='D'; M= -8, 17,-27, 23, 21,-30, 6, -4,-32, -2,-27,-22, 12,-10, 3, -8, 5, -8,-28,-32,-22, 12; /M: SY='R'; M= -5, -4,-24, -3, 6,-24, -6,-10,-26, 7,-25,-16, 0, -1, 2, 11, 7, 2,-19,-28,-18, 2; /I: I=-6; MD=-32; /M: SY='P'; M= 1,-10,-21, -9, -2,-17,-12,-12,-13, 1,-13, -9, -8, 15, -3, 0, -2, -4,-12,-20,-14, -4; D=-6; /I: I=-6; MI=-32; IM=-32; DM=-32; /M: SY='S'; M= 6,-12,-13,-16,-13, -7,-14,-12, 0,-12, -8, 1, -9,-18,-10,-13, 10, 10, 8,-25, -4,-12; /M: SY='F'; M= 2,-24,-14,-30,-24, 21,-24,-23, 10,-22, 9, 3,-21,-25,-27,-19, -9, -1, 18,-15, 2,-24; /I: I=-5; MD=-27; /M: SY='E'; M=-10, 1,-23, 4, 22,-22,-15, 0,-22, 17,-17,-10, 0, -7, 16, 21, -4, -8,-20,-19,-11, 18; D=-5; /I: I=-5; MD=-27; /M: SY='R'; M= -8, 3,-16, 0, 2,-14, -9, -1,-16, 18,-15, -7, 7, -9, 4, 22, -3, -4,-13,-14, -7, 2; D=-5; /I: I=-5; MI=-27; MD=-27; IM=-27; DM=-27; /M: SY='T'; M= 3, 1,-10, -6, -7, -2, -9,-10,-10, -9,-12,-10, 6,-11, -8, -9, 13, 16, -6,-21, -8, -7; D=-5; /I: I=-5; DM=-27; /M: SY='H'; M=-20, 0,-30, 0, 0,-20,-20,100,-30,-10,-20, 0, 10,-20, 10, 0,-10,-20,-30,-30, 20, 0; /M: SY='C'; M=-11,-14, 25,-21,-14, 7,-26,-19,-12,-21, 0, -7,-12,-27,-21,-19,-10, -3, -7,-27, -8,-16; /M: SY='S'; M= 2, -4,-19, -8, -5,-20, -7,-10,-13, 2,-18, -9, 1,-17, 0, 3, 6, -1, -6,-28,-16, -3; /M: SY='G'; M= 0, -3,-25, -1, 2,-28, 34,-13,-33,-11,-28,-20, 2,-13, -7,-13, 10, -8,-25,-27,-25, -2; /M: SY='K'; M=-11, -9,-28, -9, 3,-17,-21,-12,-20, 18,-14, -8, -8,-15, 2, 16,-11, -5,-16, -3, -5, 2; /M: SY='R'; M=-13, -1,-29, -5, 0,-22,-18, -6,-19, 18,-22,-10, 7, -4, 3, 26, -7, -8,-18,-25,-13, -2; /M: SY='H'; M=-20, 0,-30, 0, 0,-20,-20,100,-30,-10,-20, 0, 10,-20, 10, 0,-10,-20,-30,-30, 20, 0; /M: SY='K'; M= -5, -9,-27,-11, -2,-16,-22, -8,-11, 17,-11, -2, -8,-15, 5, 7,-11, -9,-10,-14, 2, 0; /M: SY='Q'; M=-13, 3,-28, 5, 15,-23,-20, 13,-23, 9,-19, -9, 1,-12, 19, 9, -3, -5,-23,-20, 0, 16; /M: SY='N'; M=-10, 19,-24, 7, -4,-21, 0, 10,-18, 0,-25,-13, 34,-19, -2, -1, 2, -6,-24,-33,-14, -4; /M: SY='L'; M= -5,-19,-16,-21,-13, -2,-26,-18, 11,-17, 17, 12,-20,-22,-14,-15,-10, 5, 14,-26, -7,-13; /M: SY='R'; M= 7, -5,-22, -6, 7,-23,-12, -9,-23, 16,-20,-12, -2,-12, 4, 19, 2, -4,-14,-23,-15, 4; /M: SY='K'; M=-14, 0, 3, 1, -1,-25,-21,-10,-28, 16,-22,-10, -2,-19, -1, 16, -9,-10,-17,-30,-15, -2; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 84 in 83 different sequences |
| Number of true positive hits | 84 in 83 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 50 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 62.69 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | K_Hofmann, N_Hulo |
| Feature key [info] | ZN_FING |
| Feature description [info] | Matrin-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
83 sequences
ATO_ARATH (Q9FG01), CIZ1_HUMAN (Q9ULV3), MATR3_HUMAN (P43243), MATR3_MOUSE (Q8K310), MATR3_RAT (P43244), NOI_DROME (O46106), PRP9_YEAST (P19736), RBM20_HUMAN (Q5T481), RBM20_MOUSE (Q3UQS8), RBM20_PIG (P0DW16), RBM20_RAT (E9PT37), RU1C1_PUCGT (E3LAN7), RU1C1_SORBI (C5XZK6), RU1C2_PUCGT (E3KIY6), RU1C2_SORBI (C5XYW4), RU1C_AEDAE (Q16IW3), RU1C_AJECG (C0NN85), RU1C_ANODA (E3X5D6), RU1C_ANOGA (Q7PXU6), RU1C_ARATH (Q56XE4), RU1C_ASPFU (Q4WQM6), RU1C_BATDJ (F4NYQ2), RU1C_BOVIN (Q32PA0), RU1C_BRAFL (C3Z1P5), RU1C_CAEBR (A8XW44), RU1C_CAEEL (P90815), RU1C_CANAL (Q59P44), RU1C_CANAW (C4YIU5), RU1C_CANLF (E2RGI3), RU1C_CHICK (E1C6F0), RU1C_CIOIN (Q1RLC9), RU1C_COPC7 (A8NYM5), RU1C_CRYNJ (Q5KC16), RU1C_DANRE (Q8JGS0), RU1C_DICDI (Q54YA5), RU1C_DROME (Q9VE17), RU1C_DROPS (Q298E0), RU1C_EMENI (Q5BBX9), RU1C_FUSV7 (C7YRT4), RU1C_HETP5 (D3B3B7), RU1C_HUMAN (P09234), RU1C_IXOSC (B7Q2M2), RU1C_MACMU (F6TFD9), RU1C_MONDO (F7ARS3), RU1C_MOUSE (Q62241), RU1C_MYCMD (Q4P2Q5), RU1C_NEMVE (A7SEP9), RU1C_NEUCR (Q1K7T5), RU1C_PEDHC (E0VI98), RU1C_PHYIT (D0NHA2), RU1C_PLABA (Q4YBG7), RU1C_PLACU (Q4XRM7), RU1C_PLAF7 (Q8IAW3), RU1C_PLAKH (B3LC82), RU1C_PLAVS (A5JZQ2), RU1C_PLAYO (Q7RNM5), RU1C_RAT(D3ZCL3), RU1C_SCHPO (Q9P794), RU1C_SCLS1 (A7EYK3), RU1C_THEAN (Q4UJ14), RU1C_THEPA (Q4N6K2), RU1C_TUBMM (D5GDH4), RU1C_VITVI (F6HQ26), RU1C_XENLA (Q03369), RU1C_XENTR (B0JYS7), RU1C_YEAST (Q05900), SAP61_SCHPO (O59706), SAP62_SCHPO (Q9P7L8), SF3A2_BOVIN (A5PJN8), SF3A2_HUMAN (Q15428), SF3A2_MOUSE (Q62203), SF3A2_RAT (Q6AXT8), SF3A3_HUMAN (Q12874), SF3A3_MOUSE (Q9D554), WBP4_CHICK (Q5F457), WBP4_HUMAN (O75554), WBP4_MOUSE (Q61048), WBP4_RAT(Q5HZF2), YNS7_SCHPO (O60138), ZMAT4_MOUSE (Q8BZ94), ZN638_HUMAN (Q14966), ZN638_MOUSE (Q61464), ZOP1_ARATH (Q7XA66)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
50 sequences
MOD5_HUMAN (Q9H3H1), MOD5_MOUSE (Q80UN9), MOD5_SCHPO (Q9UT75), MOD5_YEAST (P07884), PRP11_YEAST (Q07350), SCNM1_BOVIN (Q3ZBR0), SCNM1_DANRE (Q2YDS5), SCNM1_HUMAN (Q9BWG6), SCNM1_MOUSE (Q8K136), SCNM1_XENLA (Q3KQ71), SF3A2_DICDI (Q54B65), SNU23_CAEEL (P34670), SNU23_SCHPO (Q09776), STPAP_AILME (D2HS90), STPAP_BOVIN (Q1JPD6), STPAP_DANRE (Q4KMD7), STPAP_HUMAN (Q9H6E5), STPAP_MOUSE (Q8R3F9), STPAP_RAT (Q3MHT4), STPAP_XENTR (A9JTS5), UBA1C_ARATH (O64571), Y9776_DROME (Q9V468), Z385A_HUMAN (Q96PM9), Z385A_MOUSE (Q8VD12), Z385B_DANRE (Q6PBT9), Z385B_HUMAN (Q569K4), Z385B_MOUSE (Q8BXJ8), Z385C_HUMAN (Q66K41), Z385C_MOUSE (A2A5E6), Z385D_HUMAN (Q9H6B1), Z385D_RAT (Q6AXX3), ZMAT1_HUMAN (Q5H9K5), ZMAT1_MOUSE (Q3V0C1), ZMAT1_XENTR (Q28EG9), ZMAT2_HUMAN (Q96NC0), ZMAT2_MOUSE (Q9CPW7), ZMAT3_BOVIN (Q0IIC4), ZMAT3_HUMAN (Q9HA38), ZMAT3_MOUSE (O54836), ZMAT3_RAT (O08781), ZMAT4_BOVIN (Q0VD35), ZMAT4_HUMAN (Q9H898), ZN318_HUMAN (Q5VUA4), ZN318_MOUSE (Q99PP2), ZN346_DANRE (A2RV29), ZN346_HUMAN (Q9UL40), ZN346_MOUSE (Q9R0B7), ZN346_PONAB (Q5R4W8), ZN346_XENLA (Q8AVN9), ZN346_XENTR (B0JZ85)» more |
| PDB [Detailed view] |
73 PDB
1ZU1; 2MKD; 2MKN; 2VRD; 3CW1; 3EPH; 3EPJ; 3EPK; 3EPL; 4DGW; 4PJO; 5GM6; 5NRL; 5O9Z; 5Z56; 5Z57; 5Z58; 5ZWM; 5ZWN; 5ZWO; 6AH0; 6AHD; 6FF4; 6FF7; 6G90; 6N7P; 6N7R; 6N7X; 6QX9; 6Y50; 6Y53; 6Y5Q; 7AAV; 7ABF; 7ABG; 7ABH; 7ABI; 7DVQ; 7EVO; 7ONB; 7OQB; 7OQC; 7OQE; 7Q3L; 7Q4O; 7Q4P; 7QTT; 7VPX; 8CH6; 8H6E; 8H6J; 8H6K; 8H6L; 8HK1; 8I0P; 8I0R; 8I0S; 8I0T; 8I0U; 8IDF; 8Q7N; 8QO9; 8QPE; 8QXD; 8QZS; 8R08; 8R09; 8R0A; 8R0B; 8RM5; 8W2O; 8Y7E; 9J8P » more |