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PROSITE entry PS50208


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PURL: https://purl.expasy.org/prosite/signature/PS50208

Direct ScanProsite submission
General information about the entry

Entry name [info] CASPASE_P20
Accession [info] PS50208
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00864

Name and characterization of the entry

Description [info] Caspase family p20 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=123;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=118;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-0.4252000; R2=0.0191057; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8025.7841797; R2=5.4646840; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=468; H_SCORE=10583; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=363; H_SCORE=10009; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-30; E1=-30; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 73 in 73 different sequences
Number of true positive hits 73 in 73 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
73 sequences

CAS1A_XENLA (P55865), CAS1B_XENLA (P55867), CASP1_CANLF (Q9MZV7), 
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PDB
[Detailed view]
295 PDB

1BMQ; 1CP3; 1F1J; 1F9E; 1GFW; 1GQF; 1I3O; 1I4E; 1I4O; 1I51; 1IBC; 1ICE;
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