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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS50319


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PURL: https://purl.expasy.org/prosite/signature/PS50319

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General information about the entry

Entry name [info] LEU_RICH
Accession [info] PS50319
Entry type [info] MATRIX
Date [info] 01-APR-2002 CREATED;
01-APR-2002 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50099

Name and characterization of the entry

Description [info] Leucine-rich region profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=2;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=2;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.0691; R2=0.14261824; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=53; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=39; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: SY_I='L'; I0=-1; M0=-1;

...
 
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/M: SY='L';  M= -1, -1, -1, -1, -1, -1, -1, -1, -1, -1,  4, -1, -1, -1, -1, -1, -1, -1, -1, -1, -1, -1;
/I:         MI=0; IM=0; I=-1,-1,-1,-1,-1,-1,-1,-1,-1,-1,4,-1,-1,-1,-1,-1,-1,-1,-1,-1,-1,-1;
/M: SY='L';  M= -1, -1, -1, -1, -1, -1, -1, -1, -1, -1,  4, -1, -1, -1, -1, -1, -1, -1, -1, -1, -1, -1;
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Comments [info]

Matrix type [info] composition
Scaling database [info] db_global
Author [info] P_Bucher
Skip flag [info] TRUE
Version [info] 3