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| Entry: PS50868 |
General information about the entry
| Entry name [info] | POST_SET |
| Accession [info] | PS50868 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2002 CREATED;
10-MAY-2017 DATA UPDATE; 10-FEB-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50280 |
| Associated ProRule [info] | PRU00155 |
Name and characterization of the entry
| Description [info] | Post-SET domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=17; /DISJOINT: DEFINITION=PROTECT; N1=2; N2=16; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1220000; R2=0.0163836; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=161.0268402; R2=0.1543624; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=359; H_SCORE=216; N_SCORE=8.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=268; H_SCORE=202; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-11; D=-20; I=-20; B0=-60; B1=-60; E0=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B0=0; B1=0; BI=-105; BD=-105; /M: SY='E'; M= -7, 0,-25, -2, 6,-24,-16, -8,-17, 5,-17,-10, 1,-13, 2, -4, -2, -6,-11,-30,-18, 4; /M: SY='K'; M= -4, -5,-26, -7, 5,-25,-14, -8,-25, 14,-20,-12, -5,-10, 6, 9, -3,-10,-19,-27,-16, 4; /M: SY='M'; M=-10,-18,-20,-20, -9, -9,-28,-13, -2, -3, 0, 2,-16,-18, 0, -8,-11, -9, -1,-22, -7, -6; /M: SY='P'; M= -9, -5,-26, 0, 1,-27,-19,-14,-22, -2,-22,-15, -8, 15, -2,-10, -4, -4,-16,-32,-22, -1; /M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40; /M: SY='Y'; M=-13,-16,-19,-19, -9, -3,-25, 6,-13, -6, -7, -5, -8,-23, -2, -4, -9,-12,-14,-14, 9, -8; /M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40; /M: SY='G'; M= -2, -7,-30, -8,-10,-30, 47,-17,-38,-10,-37,-27, 3,-19,-15,-15, 0,-18,-29,-22,-28,-14; /M: SY='A'; M= 18, -9,-10, -9, -1,-19, -5,-13,-16, -4,-15,-11, -6,-11, -3, -7, 18, 6,-10,-28,-18, -2; /M: SY='P'; M= 1,-10,-21, -7, 2,-26,-17,-15,-16, 0,-18,-12,-10, 4, -3, -8, 0, -1, -8,-32,-21, 0; /M: SY='N'; M= -7, 5,-18, -4, -1,-22, -8, -2,-23, 2,-22,-14, 17,-18, -1, -1, 4, -4,-20,-30,-16, -1; /M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40; /M: SY='R'; M= -7,-11,-24,-18, -3,-25,-20, -7,-20, 12,-14, -5, -3,-18, 5, 27, -4, -4,-19,-28,-18, -2; /M: SY='G'; M= -3, -6,-29,-10,-11,-29, 31,-10,-35, -2,-33,-23, 3,-18,-10, -6, 0,-16,-27,-24,-24,-11; /M: SY='Y'; M=-12,-23,-19,-25,-16, 8,-24, -9, -9,-10, -8, -4,-18,-26,-12,-11,-11, -7, -9, 3, 11,-16; /M: SY='L'; M= -7,-34,-11,-34,-26, -1,-35,-27, 18,-17, 27, 18,-27,-27,-18,-19,-16, -9, 11,-21,-10,-25; /M: SY='G'; M= -9, -6,-27,-10,-12,-16, 12, -9,-26,-12,-25,-18, 5,-16,-11,-12, -2,-13,-23,-21,-13,-12; /I: E0=0; E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 125 in 125 different sequences |
| Number of true positive hits | 125 in 125 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 9 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 93.28 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20_shuffled |
| Author [info] | N_Hulo |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | Post-SET |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
125 sequences
ASH1L_HUMAN (Q9NR48 ), ASH1L_MOUSE (Q99MY8 ), ASH1_DROME (Q9VW15 ), ASHH1_ARATH (Q84WW6 ), ASHH2_ARATH (Q2LAE1 ), ASHH3_ARATH (Q945S8 ), ASHH4_ARATH (Q9M1X9 ), ASHR3_ARATH (Q949T8 ), ATX1_ARATH (Q9C5X4 ), ATX2_ARATH (P0CB22 ), ATX3_ARATH (Q9M364 ), ATX4_ARATH (Q9SUE7 ), ATX5_ARATH (Q8GZ42 ), C1716_DROME (Q9VYD1 ), CLR4_CRYNH (J9VWH9 ), CLR4_SCHPO (O60016 ), DIM5_NEUCR (Q8X225 ), KMT2A_HUMAN (Q03164 ), KMT2A_MOUSE (P55200 ), KMT2B_HUMAN (Q9UMN6 ), KMT2B_MOUSE (O08550 ), KMT2C_HUMAN (Q8NEZ4 ), KMT2C_MOUSE (Q8BRH4 ), KMT2D_HUMAN (O14686 ), KMT2D_MOUSE (Q6PDK2 ), MES4_CAEEL (Q9NH52 ), MES4_DROME (Q8MT36 ), MET2_CAEEL (P34544 ), NSD1_HUMAN (Q96L73 ), NSD1_MOUSE (O88491 ), NSD2_HUMAN (O96028 ), NSD2_MOUSE (Q8BVE8 ), NSD3_HUMAN (Q9BZ95 ), NSD3_MOUSE (Q6P2L6 ), SE1BA_DANRE (Q1LY77 ), SET1A_HUMAN (O15047 ), SET1A_MOUSE (E9PYH6 ), SET1B_CHICK (Q5F3P8 ), SET1B_HUMAN (Q9UPS6 ), SET1B_MOUSE (Q8CFT2 ), SET1B_XENLA (Q66J90 ), SET1B_XENTR (Q08D57 ), SET1_ASHGO (Q75D88 ), SET1_ASPFU (Q4WNH8 ), SET1_ASPOR (Q2UMH3 ), SET1_CANAL (Q5ABG1 ), SET1_CANGA (Q6FKB1 ), SET1_CHAGB (Q2GWF3 ), SET1_COCIM (Q1DR06 ), SET1_CRYNB (P0CO27 ), SET1_CRYNJ (P0CO26 ), SET1_DEBHA (Q6BKL7 ), SET1_DICDI (Q54HS3 ), SET1_DROME (Q5LJZ2 ), SET1_EMENI (Q5B0Y5 ), SET1_GIBZE (Q4I5R3 ), SET1_KLULA (Q6CIT4 ), SET1_NEUCR (Q8X0S9 ), SET1_PLAF7 (C6KTD2 ), SET1_SCHPO (Q9Y7R4 ), SET1_USTMA (Q4PB36 ), SET1_YARLI (Q6CEK8 ), SET1_YEAST (P38827 ), SET23_CAEBR (A8XI75 ), SET23_CAEEL (Q95Y12 ), SET2_ASHGO (Q757Y8 ), SET2_ASPFU (Q4WTT2 ), SET2_ASPOR (Q2UTN6 ), SET2_CAEEL (Q18221 ), SET2_CANAL (Q59XV0 ), SET2_CANGA (Q6FX50 ), SET2_CHAGB (Q2H988 ), SET2_COCIM (Q1DU03 ), SET2_CRYNB (P0CO29 ), SET2_CRYNJ (P0CO28 ), SET2_DEBHA (Q6BM04 ), SET2_EMENI (Q5ASA5 ), SET2_GIBZE (Q4IB50 ), SET2_KLULA (Q6CXP5 ), SET2_NEUCR (Q7RZU4 ), SET2_SCHPO (O14026 ), SET2_USTMA (Q4PBL3 ), SET2_YARLI (Q6C5G5 ), SET2_YEAST (P46995 ), SETB1_DROME (Q32KD2 ), SETB1_DROPS (Q28Z18 ), SETB1_HUMAN (Q15047 ), SETB1_MOUSE (O88974 ), SETB1_XENLA (Q6INA9 ), SETB2_XENLA (Q6YI93 ), SETD2_HUMAN (Q9BYW2 ), SETD2_MOUSE (E9Q5F9 ), SETMR_BOVIN (Q0VD24 ), SETMR_HUMAN (Q53H47 ), SETMR_MOUSE (Q80UJ9 ), SETMR_RAT (Q5I0M0 ), STB1B_DANRE (Q08BR4 ), SUV39_DROME (P45975 ), SUV39_DROPS (Q294B9 ), SUV91_BOVIN (Q2NL30 ), SUV91_HUMAN (O43463 ), SUV91_MOUSE (O54864 ), SUV91_PONAB (Q5RB81 ), SUV91_XENLA (Q6NRE8 ), SUV92_BOVIN (Q32PH7 ), SUV92_CHICK (Q5F3W5 ), SUV92_HUMAN (Q9H5I1 ), SUV92_MACFA (Q4R3E0 ), SUV92_MOUSE (Q9EQQ0 ), SUV92_XENTR (Q28CQ7 ), SUVH1_ARATH (Q9FF80 ), SUVH1_TOBAC (Q93YF5 ), SUVH3_ARATH (Q9C5P4 ), SUVH4_ARATH (Q8GZB6 ), SUVH5_ARATH (O82175 ), SUVH6_ARATH (Q8VZ17 ), SUVH7_ARATH (Q9C5P1 ), SUVH8_ARATH (Q9C5P0 ), SUVR3_ARATH (Q9SRV2 ), SUVR5_ARATH (O64827 ), SV91A_DANRE (Q6DGD3 ), TRR_DROME (Q8IRW8 ), TRX1_ORYSJ (Q6K431 ), TRX_DROME (P20659 ), TRX_DROVI (Q24742 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
9 sequences
EHMT2_HUMAN (Q96KQ7 ), EHMT2_MOUSE (Q9Z148 ), SET25_CAEEL (G5EEU2 ), STB1A_DANRE (Q1L8U8 ), SUVH3_CHLRE (Q5QD03 ), SUVHA_ARATH (Q3EC60 ), SUVR1_ARATH (Q946J2 ), SUVR2_ARATH (Q9FNC7 ), SUVR4_ARATH (Q8W595 )» more |
| PDB [Detailed view] |
87 PDB
1ML9; 1MVH; 1MVX; 1PEG; 2O8J; 2R3A; 2W5Y; 2W5Z; 3BO5; 3K5K; 3OOI; 3OPE; 3RJW; 4FMU; 4H12; 4NVQ; 4QEN; 4QEO; 4QEP; 4YNM; 4YNP; 4YPA; 4YPE; 4YPU; 4Z4P; 5F59; 5F5E; 5F6K; 5F6L; 5JHN; 5JIN; 5JIY; 5JJ0; 5JJY; 5JLB; 5JLE; 5LSS; 5LSU; 5LSX; 5LSY; 5LSZ; 5LT6; 5LT7; 5LT8; 5T0K; 5T0M; 5TTF; 5TUY; 5UPD; 5V21; 5V22; 5V9I; 5VSC; 5VSE; 6A5K; 6A5M; 6A5N; 6AGO; 6BOX; 6BP4; 6CEN; 6CHG; 6INE; 6J9J; 6KIU; 6KIV; 6KIW; 6KIX; 6KIZ; 6KQP; 6KQQ; 6P0R; 6PWV; 6PWW; 6U9K; 6U9M; 6U9N; 6U9R; 6UGM; 6UH5; 6VDB; 6VEN; 7BRE; 7CRO; 7CRP; 7CRQ; 7CRR » more |
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