PROSITE entry PS50955
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General information about the entry
Entry name [info] | LEM_LIKE |
Accession [info] | PS50955 |
Entry type [info] | MATRIX |
Date [info] |
01-JAN-2004 CREATED;
10-MAY-2017 DATA UPDATE; 08-NOV-2023 INFO UPDATE. |
PROSITE Doc. [info] | PDOC50954 |
Associated ProRule [info] | PRU00314 |
Name and characterization of the entry
Description [info] | LEM-like domain profile. |
Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=44; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=40; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2747363; R2=0.0091888; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2889.1398926; R2=15.6989250; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=787; H_SCORE=15244; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=569; H_SCORE=11822; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20, 0,-30, 10,-20,-20, 0, 0, 20, 0, 0,-10,-30,-30,-20, 40; /M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10, 0,-40, 0,-30,-30, 20,-10, 0,-10, 0,-10,-30,-40,-20, 10; /M: SY='P'; M=-10,-20,-40,-10, 0,-30,-20,-20,-20,-10,-30,-20,-20, 90,-10,-20,-10,-10,-30,-30,-30,-10; /M: SY='S'; M= 10, 0,-10, 0, 0,-20, 0,-10,-20,-10,-30,-20, 10,-10, 0,-10, 40, 20,-10,-40,-20, 0; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='T'; M= 0, 0,-10,-10,-10,-10,-20,-20,-10,-10,-10,-10, 0,-10,-10,-10, 20, 50, 0,-30,-10,-10; /M: SY='K'; M=-10, 0,-30, 0, 10,-30,-20,-10,-30, 50,-30,-10, 0,-10, 10, 30,-10,-10,-20,-20,-10, 10; /M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10, 0,-40, 0,-30,-30, 20,-10, 0,-10, 0,-10,-30,-40,-20, 10; /M: SY='K'; M=-10, 0,-30, 0, 10,-30,-20,-10,-30, 50,-30,-10, 0,-10, 10, 30,-10,-10,-20,-20,-10, 10; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='K'; M=-10, 0,-30, 0, 10,-30,-20,-10,-30, 50,-30,-10, 0,-10, 10, 30,-10,-10,-20,-20,-10, 10; /M: SY='S'; M= 10, 0,-10, 0, 0,-20, 0,-10,-20,-10,-30,-20, 10,-10, 0,-10, 40, 20,-10,-40,-20, 0; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='N'; M=-10, 40,-20, 20, 0,-20, 0, 10,-20, 0,-30,-20, 60,-20, 0, 0, 10, 0,-30,-40,-20, 0; /M: SY='N'; M=-10, 40,-20, 20, 0,-20, 0, 10,-20, 0,-30,-20, 60,-20, 0, 0, 10, 0,-30,-40,-20, 0; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='P'; M=-10,-20,-40,-10, 0,-30,-20,-20,-20,-10,-30,-20,-20, 90,-10,-20,-10,-10,-30,-30,-30,-10; /M: SY='N'; M=-10, 40,-20, 20, 0,-20, 0, 10,-20, 0,-30,-20, 60,-20, 0, 0, 10, 0,-30,-40,-20, 0; /M: SY='G'; M= 0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20, 0,-20,-20,-20, 0,-20,-30,-20,-30,-20; /M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10, 0,-40, 0,-30,-30, 20,-10, 0,-10, 0,-10,-30,-40,-20, 10; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /M: SY='R'; M=-20,-10,-30,-10, 0,-20,-20, 0,-30, 30,-20,-10, 0,-20, 10, 70,-10,-10,-20,-20,-10, 0; /M: SY='K'; M=-10, 0,-30, 0, 10,-30,-20,-10,-30, 50,-30,-10, 0,-10, 10, 30,-10,-10,-20,-20,-10, 10; /M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10, 0,-40, 0,-30,-30, 20,-10, 0,-10, 0,-10,-30,-40,-20, 10; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='Y'; M=-20,-20,-30,-20,-20, 30,-30, 20, 0,-10, 0, 0,-20,-30,-10,-10,-20,-10,-10, 30, 80,-20; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='Y'; M=-20,-20,-30,-20,-20, 30,-30, 20, 0,-10, 0, 0,-20,-30,-10,-10,-20,-10,-10, 30, 80,-20; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='K'; M=-10, 0,-30, 0, 10,-30,-20,-10,-30, 50,-30,-10, 0,-10, 10, 30,-10,-10,-20,-20,-10, 10; /M: SY='N'; M=-10, 40,-20, 20, 0,-20, 0, 10,-20, 0,-30,-20, 60,-20, 0, 0, 10, 0,-30,-40,-20, 0; /M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20, 0,-20; /M: SY='T'; M= 0, 0,-10,-10,-10,-10,-20,-20,-10,-10,-10,-10, 0,-10,-10,-10, 20, 50, 0,-30,-10,-10; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
Total number of hits | 8 in 8 different sequences |
Number of true positive hits | 8 in 8 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 0 |
Number of false negative sequences | 0 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 100.00 % |
Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
Matrix type [info] | protein_domain |
Scaling database [info] | reversed |
Author [info] | CJA_Sigrist |
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 1 |
Feature key [info] | DOMAIN |
Feature description [info] | LEM-like |
Version [info] | 5 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
8 sequences
LAP2A_HUMAN (P42166), LAP2A_MOUSE (Q61033), LAP2B_HUMAN (P42167), LAP2B_MOUSE (Q61029), LAP2_RAT(Q62733), THP1_BOVIN (P01249), THP2_BOVIN (P01250), THPS_BOVIN (P01251)» more
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PDB [Detailed view] |
2 PDB
1GJJ; 1H9E |