PROSITE entry PS51110
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51110 |
| Entry name [info] | SAP_A |
| Accession [info] | PS51110 |
| Entry type [info] | MATRIX |
| Date [info] |
01-APR-2005 CREATED;
01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51110 |
| Associated ProRule [info] | PRU00414 |
Name and characterization of the entry
| Description [info] | Saposin A-type domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=41; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=37; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2327433; R2=0.0107069; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=586; N_SCORE=8.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=371; N_SCORE=6.2; MODE=1; TEXT='RR'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='W'; M=-15,-30,-45,-25,-15,-10,-20,-25,-20,-15,-25,-20,-30, 30,-15,-20,-25,-20,-30, 59, 0,-15; /M: SY='T'; M= 0,-15,-10,-20,-20, -5,-25,-25, 10,-15, 0, 0,-15,-20,-20,-15, 5, 25, 25,-30,-10,-20; /M: SY='T'; M= -5, -9,-17,-14, -7,-10,-23,-14, -3,-12, 6, 1, -9,-16, 1, -9, 1, 20, -3,-25, -7, -3; /M: SY='S'; M= -2, 3,-23, 7, -3,-21, 5,-12,-27,-11,-28,-22, 3,-15, -6,-13, 14, 0,-20, -8,-14, -4; /M: SY='S'; M= 0, -8,-21, -6, 0,-21,-11,-10,-14,-10,-17,-11, -3, 8, 4,-10, 14, 5,-14,-32,-18, 1; /M: SY='K'; M=-10,-15,-25,-15, -5,-10,-25,-15, -5, 10, 10, 5,-15,-20, -5, 5,-20,-10, -5,-20, -5, -5; /M: SY='A'; M= 20, 4,-16, 2, 5,-22, -9,-14,-18, -6,-15,-15, -2, -9, -4,-14, 9, 7, -9,-27,-18, 0; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='A'; M= 35, -7,-10,-14, -8,-19, -3,-18,-12,-10,-14,-12, -4,-10, -8,-17, 18, 11, -2,-26,-19, -8; /M: SY='Q'; M= -9, -3,-30, -3, 7,-34, -2, -1,-27, 13,-24, -7, 0,-13, 29, 16, -3,-12,-27,-20,-14, 17; /M: SY='G'; M= 0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20, 0,-20,-20,-20, 0,-20,-30,-20,-30,-20; /M: SY='P'; M= -3,-13,-30, -7, 0,-27,-13,-17,-20,-10,-30,-20,-10, 55, -7,-17, 7, 0,-23,-33,-27, -7; /M: SY='E'; M= 11, 3,-23, 6, 36,-27,-13, -7,-23, 3,-17,-17, -3, -3, 10, -7, 3, -7,-20,-27,-20, 23; /M: SY='F'; M=-10,-30,-15,-35,-30, 40,-30,-25, 15,-25, 10, 5,-25,-30,-35,-20,-15, -5, 25,-10, 10,-30; /M: SY='W'; M=-18,-38,-44,-38,-28, 10,-22,-28,-12,-22, -6,-12,-38,-30,-20,-20,-38,-26,-22,115, 24,-20; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='Q'; M=-12, -2,-30, -2, 16,-36,-20, 8,-22, 14,-20, -2, 0,-12, 50, 22, -2,-10,-28,-20,-10, 32; /M: SY='S'; M= 1, 16,-16, 17, 4,-24, -2, -5,-24, -7,-30,-22, 19,-11, 0, -9, 28, 11,-17,-40,-20, 2; /M: SY='L'; M= -7,-30,-17,-30,-23, 7,-30,-23, 23,-27, 36, 17,-30,-30,-23,-20,-23, -7, 24,-23, -3,-23; /M: SY='E'; M=-12, 3,-30, 8, 33,-28,-20, -3,-30, 27,-23,-15, 0, -7, 15, 21, -5,-10,-25,-25,-15, 23; /M: SY='Q'; M= -5, 0,-20, -5, 5,-25,-20, -5,-15, 0,-15, -5, 0,-10, 25, 0, 10, 20,-15,-25,-10, 15; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='L'; M= -2,-21,-15,-21,-16, -1,-21,-19, 10,-22, 18, 6,-18,-24,-16,-17, -5, 1, 12,-28, -8,-16; /M: SY='Q'; M=-13, 17,-30, 24, 20,-40,-17, 7,-27, 7,-23,-10, 7,-10, 39, 3, 0,-10,-30,-27,-13, 30; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='G'; M=-10,-10,-30,-10,-10,-25, 25,-10,-35, 5,-25,-15, 0,-20, -5, 25, -5,-15,-25,-20,-20,-10; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='L'; M= -5,-30,-15,-30,-25, 5,-30,-25, 25,-25, 30, 15,-30,-30,-25,-20,-20, -5, 30,-25, -5,-25; /M: SY='G'; M= -5, -5,-30, -5, -5,-30, 25,-15,-35, 15,-30,-15, 0,-15, -5, 5, -5,-15,-25,-20,-20, -5; /M: SY='H'; M=-20, 0,-30, 0, 0,-20,-20,100,-30,-10,-20, 0, 10,-20, 10, 0,-10,-20,-30,-30, 20, 0; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='L'; M=-10,-19,-24,-19, -6, -8,-26, -9, 6,-16, 25, 13,-19,-23, 9, -9,-19,-10, -4,-20, -4, 2; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /M: SY='E'; M= -9, 7,-24, 5, 24,-19,-17, -1,-15, 1,-12, -2, 5, -9, 9, -3, 0, 0,-18,-30,-14, 16; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='W'; M=-20,-40,-50,-40,-30, 10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150, 30,-20; /M: SY='G'; M= 2, 1,-21, -2,-10,-25, 35,-12,-30,-14,-30,-20, 12,-16,-10,-14, 16, -3,-23,-30,-25,-10; /M: SY='H'; M=-15, 0,-30, 0, 5,-25,-20, 45,-30, 20,-25, -5, 5,-15, 10, 15,-10,-15,-25,-25, 5, 5; /M: SY='P'; M= -5,-25,-25,-20,-15,-15,-25,-25, 5,-15,-10, -5,-25, 30,-20,-20,-10, -5, 10,-30,-20,-20; /M: SY='G'; M= 8, -7,-20,-12,-15,-21, 28,-20,-25,-15,-20,-15, -2,-15,-15,-17, 9, 7,-15,-23,-21,-15; /M: SY='A'; M= 35,-16,-10,-23,-16,-14, -9,-23, 2,-13, -4, -4,-16,-16,-16,-20, 4, 0, 15,-23,-17,-16; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 21 in 14 different sequences |
| Number of true positive hits | 20 in 13 different sequences |
| Number of 'unknown' hits | 1 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | PS_Langendijk_Genevaux |
| Feature key [info] | DOMAIN |
| Feature description [info] | Saposin A-type |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
13 sequences
PSPB_BOVIN (P15781), PSPB_CANLF (P17129), PSPB_HUMAN (P07988), PSPB_MOUSE (P50405), PSPB_RABIT (P15285), PSPB_RAT(P22355), SAPL1_HUMAN (Q6NUJ1), SAPL1_MOUSE (Q8C1C1), SAP_BOVIN (P26779), SAP_CHICK (O13035), SAP_HUMAN (P07602), SAP_MOUSE (Q61207), SAP_RAT (P10960)» more
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| UniProtKB/Swiss-Prot 'Unknown' sequences |
1 sequence
GILT_CARAU (E7E2N8) |