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PROSITE entry PS51183


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PURL: https://purl.expasy.org/prosite/signature/PS51183

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General information about the entry

Entry name [info] JMJN
Accession [info] PS51183
Entry type [info] MATRIX
Date [info] 01-FEB-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51183
Associated ProRule [info] PRU00537

Name and characterization of the entry

Description [info] JmjN domain profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=42;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=38;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0609195; R2=0.0138589; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2398.1782227; R2=1.2883356; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=465; H_SCORE=2997; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=321; H_SCORE=2812; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;

...
 
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='I';  M= -2,-21, -8,-30,-25, -6,-30,-25, 26,-24,  7,  8,-13,-22,-20,-25,-12, -7, 20,-26, -9,-25;
/M: SY='P';  M= -9,-21,-34,-14, -4,-22,-22,-19,-10,-13,-14,-10,-21, 56, -9,-18,-12, -9,-17,-28,-23,-10;
/M: SY='V';  M= -1,-17,-15,-20,-14, -7,-24,-20,  9,-10,  1,  5,-16,-20,-14, -8, -3,  7, 20,-27,-10,-15;
/M: SY='F';  M=-14,-30,-20,-37,-29, 46,-32,-23, 15,-28, 16,  7,-23,-28,-33,-22,-19, -8, 14, -5, 15,-29;
/M: SY='R';  M=-12, -4,-26, -7,  1, -9,-22, -3,-10,  5, -9, -6,  0,-18,  0,  8, -8, -3,-12,-16,  5, -2;
/M: SY='P';  M= -9,-20,-34,-14, -4,-21,-22,-20,-12,-14,-14,-12,-20, 61,-12,-19,-11, -5,-21,-28,-23,-12;
/M: SY='T';  M=  3, -1,-15, -7, -4,-17,-15, -7,-17,  0,-18,-11,  2,-11, -3, -4, 15, 25, -7,-29,-10, -4;
/M: SY='M';  M= -8,-13,-30,-14, -2,-12,-14,-10,-10,  1,-10,  4,-13,-11, -2, -5,-14,-13,-12,  1, -1, -2;
/M: SY='E';  M= -5,  1,-27,  3, 24,-27,-17, -3,-23, 17,-20, -8, -1, -8, 18, 11, -1, -7,-21,-25,-14, 20;
/M: SY='E';  M=-11, 13,-30, 23, 54,-31,-19,  1,-30,  9,-21,-19,  2, -1, 21,  0,  0,-10,-30,-30,-19, 38;
/M: SY='F';  M=-18,-29,-20,-38,-28, 67,-29,-18,  4,-28, 15,  7,-21,-29,-35,-19,-21,-10,  2,  5, 25,-27;
/M: SY='K';  M= -1, -1,-23,  0,  4,-24,-16, -6,-19,  5,-20,-11, -2, -2,  2,  1,  3,  2,-12,-28,-14,  2;
/M: SY='D';  M=-17, 42,-27, 49, 13,-33, -8,  3,-34,  3,-29,-26, 29,-14,  1,  0,  2, -7,-29,-38,-19,  6;
/M: SY='P';  M=-11,-21,-31,-19,-11,  1,-15,-18,-13,-16,-15, -8,-17, 37,-18,-19,-11, -8,-18,-18,-12,-16;
/M: SY='L';  M= -9,-21,-25,-23,-11, -2,-27,-13, 14,-18, 17, 15,-19,-15, -7,-16,-16, -8,  4,-19,  0,-11;
/M: SY='D';  M= -4,  1,-24,  3,  2,-21, -3, -8,-19, -1,-17,-12,  0,-14,  0, -6,  2, -5,-16,-24,-10,  0;
/M: SY='Y';  M=-20,-25,-25,-29,-25, 53,-30,  2,  0,-19,  5,  0,-20,-30,-24,-15,-20,-10, -5, 21, 57,-25;
/M: SY='I';  M=-12,-28,-19,-37,-28,  9,-37,-24, 34,-28, 16, 14,-21,-24,-21,-27,-20,-10, 20,-15,  8,-28;
/M: SY='E';  M= -4,  6,-25, 12, 30,-27,-14, -5,-27, 11,-23,-18,  3, -6, 11,  5,  6, -3,-22,-30,-18, 20;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='R';  M= -5, -9,-24, -9,  1,-17,-19, -5,-14,  9, -9, -4, -5,-16,  1, 10, -5, -5,-10,-24, -9, -1;
/M: SY='I';  M= -9,-26,-24,-30,-22,  5,-34,-19, 29,-22, 16, 12,-22,-24,-18,-21,-18, -8, 22,-14, 10,-23;
/M: SY='E';  M= -8, 10,-24,  9, 15,-24,-14, -3,-25, 10,-22,-16, 11,-12,  6, 15,  4,  1,-21,-29,-16,  9;
/M: SY='Q';  M= -9,  1,-29,  5,  7,-26,-17, -1,-23, 10,-23,-12, -1, -1, 15,  9, -2, -7,-23,-22, -8, 10;
/M: SY='M';  M=-10,-14,-24,-19,-12, -2,-20,-10,  2, -9,  6,  7,-10,-21, -5, -6,-12, -5, -3,-17,  1,-10;
/M: SY='G';  M= 20,-11,-21,-15,-17,-25, 37,-21,-25,-16,-20,-15, -5,-17,-17,-20,  3,-11,-14,-21,-25,-17;
/M: SY='E';  M= -5, -7,-24, -7,  7,-18,-14, -4,-13,  2,-10, -3, -6,-14,  1,  1, -4, -7,-10,-25,-12,  3;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K';  M= -9, -4,-27, -3,  7,-25,-19,-11,-23, 31,-24,-10, -3, -8,  5, 22, -5, -7,-14,-24,-12,  5;
/M: SY='Y';  M= -4,-11,-22,-14,-14, 13,-18,  6, -7,-11, -9, -7, -7,-23, -9,-11, -1, -2, -9,  3, 37,-14;
/M: SY='G';  M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='I';  M=  5,-23, -7,-31,-23, -6,-25,-22, 20,-21, 10, 14,-19,-21,-16,-23,-12, -7, 16,-24, -8,-21;
/M: SY='C';  M=  1,-24, 33,-30,-27, -9,-27,-28,  5,-24,  1, -1,-23,-30,-26,-24,-10, -5, 18,-34,-17,-27;
/M: SY='K';  M=-12, -3,-23, -4,  6,-27,-20, -9,-30, 42,-27,-10, -1,-14,  8, 36,-10,-10,-20,-21,-11,  6;
/M: SY='V';  M= -5,-30,-18,-34,-29,  1,-34,-29, 36,-25, 18, 15,-26,-26,-25,-24,-16, -5, 39,-25, -5,-29;
/M: SY='I';  M= -7,-26,-22,-31,-24, -4,-33,-26, 30,-15,  9, 11,-21,-23,-19,-14,-15, -6, 30,-24, -5,-24;
/M: SY='P';  M= -7,-20,-36,-14, -4,-26,-21,-19,-13, -9,-23,-15,-18, 65, -9,-14,-10, -9,-22,-28,-25,-11;
/M: SY='P';  M=-10,-21,-39,-13, -3,-27,-22,-21,-13,-12,-25,-16,-20, 80,-11,-21,-11,-10,-24,-29,-27,-12;
/M: SY='P';  M=  0, -2,-25,  2,  6,-25,-13,-13,-18, -3,-23,-17, -3, 21, -4,-11,  3, -3,-16,-31,-22, -1;
/M: SY='D';  M= -3, 11,-23, 14,  9,-20,  4, -8,-27, -7,-23,-20,  9,-12, -4,-11,  7, -5,-21,-29,-18,  3;
/M: SY='W';  M=-12,-34,-37,-37,-28, 20,-21,-27,-11,-21,-11,-13,-32,-28,-24,-20,-29,-21,-15, 92, 22,-22;
/M: SY='K';  M=-10,  0,-16,  0,  1,-22,-18, -9,-21, 13,-15, -9,  0,-16,  3, 12, -4, -3,-15,-27,-12,  1;
/M: SY='P';  M=-10,-10,-21, -7,  2,-27,-19,-15,-21,  0,-26,-15, -9, 43, -5,-10, -8, -9,-25,-30,-24, -5;
/M: SY='P';  M=-12,-14,-33, -9,  5,-17,-22,-12,-19,  0,-18,-12,-13, 33, -1, -1,-10,-10,-23,-23,-16,  0;
/I:         E1=0; IE=-105; DE=-105;
» more

Post-processing [info]

PROMOTED_BY PS51184

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 57 in 57 different sequences
Number of true positive hits 57 in 57 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] JmjN
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 57 sequences 

ECM5_YEAST  (Q03214), ELF6_ARATH  (Q6BDA0), GIS1_YEAST  (Q03833), 

JARD2_CHICK (Q5F363), JARD2_DANRE (Q1LVC2), JARD2_DROME (Q9VT00), 
JARD2_HUMAN (Q92833), JARD2_MOUSE (Q62315), JHD2_YEAST  (P47156), 
JM703_ORYSJ (Q53WJ1), JM705_ORYSJ (Q5N712), JM706_ORYSJ (Q336N8), 
JMJ13_ARATH (F4KIX0), JMJ14_ARATH (Q8GUI6), JMJ15_ARATH (O64752), 
JMJ16_ARATH (C0SUT9), JMJ18_ARATH (F4I6G4), JMJ19_ARATH (Q8L7T6), 
JMJ2_SCHPO  (Q9US53), JMJ3_SCHPO  (O94691), KD5BB_DANRE (Q6IQX0), 
KDM4A_DROME (Q9V333), KDM4A_HUMAN (O75164), KDM4A_MOUSE (Q8BW72), 
KDM4A_PONAB (Q5RD88), KDM4B_DROME (Q9V6L0), KDM4B_HUMAN (O94953), 
KDM4B_MOUSE (Q91VY5), KDM4C_HUMAN (Q9H3R0), KDM4C_MOUSE (Q8VCD7), 
KDM4D_HUMAN (Q6B0I6), KDM4D_MOUSE (Q3U2K5), KDM4D_RAT   (A1A5Q5), 
KDM4E_HUMAN (B2RXH2), KDM4F_HUMAN (A0A1W2PPD8), KDM4_CAEEL  (Q9U297), 
KDM5A_HUMAN (P29375), KDM5A_MOUSE (Q3UXZ9), KDM5B_CHICK (Q5F3R2), 
KDM5B_HUMAN (Q9UGL1), KDM5B_MOUSE (Q80Y84), KDM5C_CANLF (Q38JA7), 
KDM5C_HUMAN (P41229), KDM5C_MOUSE (P41230), KDM5C_PIG   (A1YVX4), 
KDM5D_CANLF (Q30DN6), KDM5D_HUMAN (Q9BY66), KDM5D_MOUSE (Q62240), 
KDM5D_PANTR (Q5XUN4), KDM5_CAEBR  (Q61T02), KDM5_CAEEL  (Q23541), 
KDM5_DROME  (Q9VMJ7), LID2_SCHPO  (Q9HDV4), MSC1_SCHPO  (Q9UT79), 
REF6_ARATH  (Q9STM3), RPH1_YEAST  (P39956), SE14_ORYSJ  (Q10RP4)
» more

PDB
[Detailed view]		 475 PDB

pdb_00002gp3; pdb_00002gp5; pdb_00002oq6; pdb_00002oq7; pdb_00002os2; pdb_00002ot7; pdb_00002ox0; pdb_00002p5b; pdb_00002pxj; pdb_00002q8c; pdb_00002q8d; pdb_00002q8e; pdb_00002vd7; pdb_00002w2i; pdb_00002wwj; pdb_00002xml; pdb_00002ybk; pdb_00002ybp; pdb_00002ybs; pdb_00003dxt; pdb_00003dxu; pdb_00003njy; pdb_00003opt; pdb_00003opw; pdb_00003pdq; pdb_00003rvh; pdb_00003u4s; pdb_00004ai9; pdb_00004bis; pdb_00004d6q; pdb_00004d6r; pdb_00004d6s; pdb_00004gd4; pdb_00004hon; pdb_00004hoo; pdb_00004igo; pdb_00004igp; pdb_00004igq; pdb_00004lxl; pdb_00004ura; pdb_00004v2v; pdb_00004v2w; pdb_00004xdo; pdb_00004xdp; pdb_00005a1f; pdb_00005a3n; pdb_00005a3p; pdb_00005a3t; pdb_00005a3w; pdb_00005a7n; pdb_00005a7o; pdb_00005a7p; pdb_00005a7q; pdb_00005a7s; pdb_00005a7w; pdb_00005a80; pdb_00005anq; pdb_00005ceh; pdb_00005e6h; pdb_00005f2s; pdb_00005f2w; pdb_00005f32; pdb_00005f37; pdb_00005f39; pdb_00005f3c; pdb_00005f3e; pdb_00005f3g; pdb_00005f3i; pdb_00005f5a; pdb_00005f5c; pdb_00005f5i; pdb_00005fjh; pdb_00005fjk; pdb_00005fp4; pdb_00005fp7; pdb_00005fp8; pdb_00005fp9; pdb_00005fpa; pdb_00005fpb; pdb_00005fpl; pdb_00005fpu; pdb_00005fpv; pdb_00005fun; pdb_00005fup; pdb_00005fv3; pdb_00005fwe; pdb_00005fwj; pdb_00005fy4; pdb_00005fy5; pdb_00005fy8; pdb_00005fy9; pdb_00005fyb; pdb_00005fyc; pdb_00005fyh; pdb_00005fyi; pdb_00005fys; pdb_00005fyt; pdb_00005fyu; pdb_00005fyv; pdb_00005fyy; pdb_00005fyz; pdb_00005fz0; pdb_00005fz1; pdb_00005fz3; pdb_00005fz4; pdb_00005fz6; pdb_00005fz7; pdb_00005fz8; pdb_00005fz9; pdb_00005fza; pdb_00005fzb; pdb_00005fzc; pdb_00005fzd; pdb_00005fze; pdb_00005fzf; pdb_00005fzg; pdb_00005fzh; pdb_00005fzi; pdb_00005fzk; pdb_00005fzl; pdb_00005fzm; pdb_00005isl; pdb_00005ivb; pdb_00005ivc; pdb_00005ive; pdb_00005ivf; pdb_00005ivj; pdb_00005ivv; pdb_00005ivy; pdb_00005iw0; pdb_00005iwf; pdb_00005k4l; pdb_00005kr7; pdb_00005lw9; pdb_00005lwb; pdb_00005ly1; pdb_00005ly2; pdb_00005ph0; pdb_00005ph1; pdb_00005ph2; pdb_00005ph3; pdb_00005ph4; pdb_00005ph5; pdb_00005ph6; pdb_00005ph7; pdb_00005ph8; pdb_00005ph9; pdb_00005pha; pdb_00005phb; pdb_00005phc; pdb_00005phd; pdb_00005phe; pdb_00005phf; pdb_00005phg; pdb_00005phh; pdb_00005phi; pdb_00005phj; pdb_00005phk; pdb_00005phl; pdb_00005phm; pdb_00005phn; pdb_00005pho; pdb_00005php; pdb_00005phq; pdb_00005phr; pdb_00005phs; pdb_00005pht; pdb_00005phu; pdb_00005phv; pdb_00005phw; pdb_00005phx; pdb_00005phy; pdb_00005phz; pdb_00005pi0; pdb_00005pi1; pdb_00005pi2; pdb_00005pi3; pdb_00005pi4; pdb_00005pi5; pdb_00005pi6; pdb_00005pi7; pdb_00005pi8; pdb_00005pi9; pdb_00005pia; pdb_00005pib; pdb_00005pic; pdb_00005pid; pdb_00005pie; pdb_00005pif; pdb_00005pig; pdb_00005pih; pdb_00005pii; pdb_00005pij; pdb_00005pik; pdb_00005pil; pdb_00005pim; pdb_00005pin; pdb_00005pio; pdb_00005pip; pdb_00005piq; pdb_00005pir; pdb_00005pis; pdb_00005pit; pdb_00005piu; pdb_00005piv; pdb_00005piw; pdb_00005pix; pdb_00005piy; pdb_00005piz; pdb_00005pj0; pdb_00005pj1; pdb_00005pj2; pdb_00005pj3; pdb_00005pj4; pdb_00005pj5; pdb_00005pj6; pdb_00005pj7; pdb_00005pj8; pdb_00005pj9; pdb_00005pja; pdb_00005pjb; pdb_00005pjc; pdb_00005pjd; pdb_00005pje; pdb_00005pjf; pdb_00005pjg; pdb_00005pjh; pdb_00005pji; pdb_00005pjj; pdb_00005pjk; pdb_00005pjl; pdb_00005pjm; pdb_00005pjn; pdb_00005pjo; pdb_00005pjp; pdb_00005pjq; pdb_00005pjr; pdb_00005pjs; pdb_00005pjt; pdb_00005pju; pdb_00005pjv; pdb_00005pjw; pdb_00005pjx; pdb_00005pjy; pdb_00005pjz; pdb_00005pk0; pdb_00005pk1; pdb_00005pk2; pdb_00005pk3; pdb_00005pk4; pdb_00005pk5; pdb_00005pk6; pdb_00005pk7; pdb_00005pk8; pdb_00005pk9; pdb_00005pka; pdb_00005pkb; pdb_00005pkc; pdb_00005pkd; pdb_00005pke; pdb_00005pkf; pdb_00005pkg; pdb_00005pkh; pdb_00005pki; pdb_00005pkj; pdb_00005pkk; pdb_00005pkl; pdb_00005pkm; pdb_00005pkn; pdb_00005pko; pdb_00005pkp; pdb_00005pkq; pdb_00005pkr; pdb_00005pks; pdb_00005pkt; pdb_00005pku; pdb_00005pkv; pdb_00005pkw; pdb_00005pkx; pdb_00005pky; pdb_00005pkz; pdb_00005pl0; pdb_00005pl1; pdb_00005pl2; pdb_00005pl3; pdb_00005pl4; pdb_00005pl5; pdb_00005pl6; pdb_00005pl7; pdb_00005pl8; pdb_00005pl9; pdb_00005pla; pdb_00005plb; pdb_00005plc; pdb_00005pld; pdb_00005ple; pdb_00005plf; pdb_00005plg; pdb_00005plh; pdb_00005pli; pdb_00005plj; pdb_00005plk; pdb_00005pll; pdb_00005plm; pdb_00005pln; pdb_00005plo; pdb_00005plp; pdb_00005plq; pdb_00005plr; pdb_00005pls; pdb_00005plt; pdb_00005plu; pdb_00005plv; pdb_00005plw; pdb_00005plx; pdb_00005ply; pdb_00005plz; pdb_00005pm0; pdb_00005pm1; pdb_00005pm2; pdb_00005pm3; pdb_00005pm4; pdb_00005pm5; pdb_00005pm6; pdb_00005pm7; pdb_00005pm8; pdb_00005pm9; pdb_00005pma; pdb_00005pmb; pdb_00005pmc; pdb_00005pmd; pdb_00005pme; pdb_00005pmf; pdb_00005pmg; pdb_00005pmh; pdb_00005pmi; pdb_00005pmj; pdb_00005pmk; pdb_00005pml; pdb_00005pmm; pdb_00005pmn; pdb_00005pmo; pdb_00005pmp; pdb_00005pmq; pdb_00005pmr; pdb_00005pms; pdb_00005pmt; pdb_00005pmu; pdb_00005pmv; pdb_00005pmw; pdb_00005pmx; pdb_00005pmy; pdb_00005pmz; pdb_00005pn0; pdb_00005pn1; pdb_00005pn2; pdb_00005pn3; pdb_00005pn4; pdb_00005pn5; pdb_00005pn6; pdb_00005pn7; pdb_00005pn8; pdb_00005pn9; pdb_00005pna; pdb_00005pnb; pdb_00005pnc; pdb_00005pnd; pdb_00005pne; pdb_00005pnf; pdb_00005png; pdb_00005pnh; pdb_00005pni; pdb_00005pnj; pdb_00005pnk; pdb_00005pnl; pdb_00005pnm; pdb_00005pnn; pdb_00005pno; pdb_00005pnp; pdb_00005pnq; pdb_00005pnr; pdb_00005pns; pdb_00005pnu; pdb_00005pnv; pdb_00005pnw; pdb_00005tvr; pdb_00005tvs; pdb_00005v9p; pdb_00005v9t; pdb_00005vgi; pdb_00005vmp; pdb_00005ykn; pdb_00005yko; pdb_00006bgu; pdb_00006bgv; pdb_00006bgw; pdb_00006bgx; pdb_00006bgy; pdb_00006bgz; pdb_00006bh0; pdb_00006bh1; pdb_00006bh2; pdb_00006bh3; pdb_00006bh4; pdb_00006bh5; pdb_00006cg1; pdb_00006cg2; pdb_00006dq4; pdb_00006dq5; pdb_00006dq6; pdb_00006dq7; pdb_00006dq8; pdb_00006dq9; pdb_00006dqa; pdb_00006dqb; pdb_00006dqc; pdb_00006dqd; pdb_00006dqe; pdb_00006dqf; pdb_00006ein; pdb_00006eiu; pdb_00006eiy; pdb_00006ej0; pdb_00006ej1; pdb_00006ek6; pdb_00006ete; pdb_00006etg; pdb_00006ets; pdb_00006ett; pdb_00006etu; pdb_00006etv; pdb_00006etw; pdb_00006f5q; pdb_00006f5r; pdb_00006f5s; pdb_00006f5t; pdb_00006g5w; pdb_00006g5x; pdb_00006h0w; pdb_00006h0x; pdb_00006h0y; pdb_00006h0z; pdb_00006h10; pdb_00006h11; pdb_00006h4o; pdb_00006h4p; pdb_00006h4q; pdb_00006h4r; pdb_00006h4s; pdb_00006h4t; pdb_00006h4u; pdb_00006h4v; pdb_00006h4w; pdb_00006h4x; pdb_00006h4y; pdb_00006h4z; pdb_00006h50; pdb_00006h51; pdb_00006h52; pdb_00006h8p; pdb_00006hgt; pdb_00006ip0; pdb_00006ip4; pdb_00006rbi; pdb_00007dyg; pdb_00007dyq; pdb_00007eqv; pdb_00007jm5; pdb_00007kso; pdb_00008vmi; pdb_00008vml; pdb_00008wd3; pdb_00008wug; pdb_00009gle; pdb_00009gp1
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