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PROSITE entry PS51369


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General information about the entry

Entry name [info] TCP
Accession [info] PS51369
Entry type [info] MATRIX
Date [info] 01-FEB-2008 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51369
Associated ProRule [info] PRU00701

Name and characterization of the entry

Description [info] TCP domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=59;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=54;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0454526; R2=0.0077427; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6766.3911133; R2=1.6415800; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=705; H_SCORE=7924; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=447; H_SCORE=7500; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-56; D=-100; I=-100; B1=-1000; E1=-1000; MI=-250; MD=-250; IM=-250; DM=-250;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-250; BD=-250;
/M: SY='R';  M= -52,-109, -92, -46,-111,  15, -95,-109,   2,-110,-102,  -3, -15, -83,  28, -11,  -1, -60,-113,-104;
/M: SY='K';  M= -93,-107, -91, -77,-108,-104, -94,-100,  73,-104, -96, -83, -98, -77, -15, -61,   2, -19,-109, -98;
/M: SY='D';  M=-100,-114,  93, -66,-121, -42, -87,-119, -89,-117,-116, -69,-100, -88, -97, -89, -91, -93,-135,-104;
/M: SY='R';  M= -99,-116, -97, -85,-109, -32, -87,-116, -25,-109, -98, -89,-108, -75,  88, -94, -99,-110, -42, -96;
/I:         I=-30; MI=0; MD=-76; IM=0; DM=-76;
/M: SY='H';  M=-103,-114, -86, -87,-101,-104, 125,-119, -91,-102, -87, -76,-103, -80, -85, -92,-101,-119,-137, -70;
/I:         I=-30; MI=0; MD=-76; IM=0; DM=-76;
/M: SY='S';  M= -79, -97, -92, -92,-102, -90, -96, -67, -51, -58, -96, -81, -98, -87, -90,  67,  28, -23,-116, -98;
/M: SY='K';  M= -96,-110, -15, -74,-113, -85, -91,-113,  83,-112,-100, -80, -96, -74, -59, -90, -91,-109,-107, -99;
/M: SY='V';  M= -88,-102,-116,-111, -84,-118,-117,  43,-108, -60, -52,-110,-109,-109,-110,-101, -85,  63,-114, -92;
/I:         I=-22; MD=-56;
/M: SY='C';  M= -36,  57,-114,-113, -74,-119,   6, -67, -53, -66, -70, -12,-126, -92,  -2, -97, -90, -36, -65,  -3; D=-22;
/I:         I=-22; MD=-56;
/M: SY='T';  M= -96,-105, -17,-100,-112,-111,-109,-103,-100,-107,-104, -88,-102,-104, -93, -80,  79, -95,-132,-109; D=-22;
/I:         I=-22; MD=-56;
/M: SY='A';  M=  45,-105,-103, -23,-114, -94,-107,-102,-101, -89, -58, -99, -89, -96,-106,  20, -89, -31,-119,-110; D=-22;
/I:         I=-22; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='Q';  M=-100,-122, -98, -86,-123,   2,   0,-121,  10,-112,-104, -91,-109,  60,  17, -94,-104,-119,-115,-103; D=-22;
/I:         I=-22; DM=-56;
/M: SY='G';  M= -52,-101,  21,  14,-107,  73, -88,-112, -86,-108, -99, -23, -90, -82, -94, -74, -88,-106,-102,-100;
/M: SY='P';  M= -71, -97, -94, -92, -20,  41, -66, -37, -92,  14,  25, -88,  52, -90, -97, -83, -49,  -2, -96, -86;
/M: SY='R';  M= -89,-105, -85, -73, -98, -99, -74,-105, -46, -97, -86, -78, -60, -62, 104, -83, -87, -98, -98, -84;
/M: SY='D';  M= -19,-100,  87, -57,-107,  38, -80,-107, -81,-105,-101, -46, -89, -79, -89, -52, -81, -97,-112, -94;
/M: SY='R';  M= -89,-105, -85, -73, -98, -95, -74,-105, -45, -97, -86, -78, -97, -62, 104, -75, -87, -98, -98, -84;
/M: SY='R';  M= -86, -16, -83, -71, -95, -96, -72,-102, -44, -94, -84, -76, -95, -60, 105, -38, -84, -95, -96, -82;
/M: SY='M';  M= -77, -89,-102, -96, -72,-102, -93,  49, -92, -54,  82, -93, -93, -89, -93, -87, -15,  55, -99, -76;
/I:         I=-26; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='R';  M= -86,-103, -83, -71, -95, -97, -72,-102, -43, -94, -83, -76, -95, -60, 106, -80, -55, -95, -95, -82;
/M: SY='M';  M= -85, -89,-104, -95, -63,-103, -85, -22, -94,  69,  71, -99, -65, -87, -92, -77, -81, -38, -92, -72;
/M: SY='S';  M= -49, -90, -78, -76, -97, -74, -81, -93, -78, -99, -90, -52,  67, -73, -85,  83, -61, -89,-101, -90;
/M: SY='V';  M=  29, -87, -95, -91, -69, -91, -92,  25, -90,  32, -35, -27, -31, -87, -93, -27, -74,  32, -97, -80;
/M: SY='P';  M= -33, -95,  32,  22, -89,   3,   9, -33, -33,  -2,  16, -26,  39,   2, -81, -33, -39, -61, -99, -84;
/M: SY='C';  M= -48,  82, -94, -93, -77, -96, -96,  43, -89, -36, -13, -84, -93, -91, -94, -46,  43,  32,-103, -83;
/M: SY='A';  M=  84, -81, -85, -78, -94, -69, -86, -84, -78, -87, -80, -79, -24, -76, -28,  -5, -39, -72, -95, -89;
/M: SY='R';  M=  41, -92, -86, -78, -87, -68, -82,  33, -19, -69, -74, -27, -25, -71,  67, -74, -77, -55, -94, -83;
/M: SY='R';  M= -11, -97, -44, -13, -97, -42, -74, -97,  55, -93, -83, -71, -60,  45,  63, -74, -79, -92,  -6, -82;
/M: SY='F';  M= -86,   7,-103, -99,  93,-101, -89,  21, -95,   1, -62, -94,-100,-100, -94, -84, -80,  12, -69, -48;
/I:         I=-22; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='F';  M= -58, -90,-100, -97, 101, -98, -76, -67, -92, -34, -67, -92,-102, -97, -89, -65, -83, -72, -55,  66;
/M: SY='D';  M= -15, -95,  80, -10,-101, -19, -36, -97, -62, -95, -88, -14, -83,  59,  -6,  -9, -60, -93,-103, -84;
/M: SY='L';  M= -38, -85, -99, -92, -58, -99, -86,   6, -92,  75, -48, -96, -66, -86, -91, -30, -76,  -7, -89, -71;
/M: SY='Q';  M= -35, -91, -70, -57, -97, -82, -52, -85, -60, -84, -74, -11, -80, 108, -62, -60,  55, -83, -92, -78;
/M: SY='D';  M= -79, -94,  90,  21, -96, -12, -67, -98, -29, -94, -89, -23, -81, -61,  53, -70, -73, -94,-102, -57;
/M: SY='M';  M= -70,   7, -72,  45, -76, -88, -68, -37,  -6, -16, 100, -71, -81, -26,  50, -76, -33, -61, -89, -72;
/M: SY='L';  M= -79, -81, -97, -89, -17, -98, -81, -44, -90,  87, -41, -96, -96, -83, -87, -80, -75, -23, -83, -64;
/M: SY='G';  M= -63, -73, -37, -50, -20,  94, -80, -99, -42, -94, -85, -21, -81, -57, -23, -62, -79, -77, -85, -85;
/M: SY='F';  M= -32, -53, -88, -86,  89, -91,  67, -60, -84,   3, -60, -76, -93, -84, -81, -79, -32,   7, -64,  40;
/M: SY='D';  M= -75, -89,  96, -28, -94, -38, -65, -93,  36, -92, -87,   8, -78, -60,  18,  -9, -67, -65,-102, -80;
/M: SY='K';  M= -69, -86, -67, -17, -87, -78, -68, -87,  79, -86, -65, -60, -75,  48,  22,  22,  21, -82,  16, -63;
/M: SY='P';  M=  58, -86,  49, -26, -92, -31, -76, -39, -72, -86, -79, -33,  79, -71, -80, -60, -67, -76, -92, -86;
/M: SY='S';  M= -55, -54, -69, -71, -88,  38, -73, -89, -70, -91, -83, -47, -24, -11, -69,  93, -54, -82, -92, -80;
/M: SY='K';  M= -41, -89, -60,  39, -92, -72, -34, -91,  85, -78, -78,  22, -75,  34, -17, -66, -69, -87, -87, -78;
/M: SY='T';  M=   9, -74, -21, -71, -80, -76, -79, -70, -70, -75, -72, -20, -65, -73, -77,  -6, 102, -18, -99, -78;
/M: SY='I';  M= -72, -83, -96, -91, -22, -35, -92,  66, -89,  35, -48, -89, -90, -87, -90, -83, -69,  56, -88, -68;
/M: SY='E';  M= -42,  -7,  63,  78, -96, -23, -66, -95, -57, -90, -85, -60, -73,  33,  -4, -21, -71, -89, -96, -82;
/M: SY='W';  M= -86,  -1,-112, -91, -53, -85,-113, -85, -83, -82, -85,-105, -91, -84, -77, -92, -39, -98, 174, -40;
/M: SY='L';  M= -79, -81, -96, -88, -52, -98, -34, -44, -89,  89, -25, -95, -87, -82, -86, -89, -75, -46, -83, -65;
/M: SY='L';  M= -78, -82, -95, -89,  40, -96, -80,  34, -88,  71,  28, -90, -72, -83, -86, -40, -73, -49, -77, -54;
/M: SY='T';  M= -23,  22, -15,  -7, -84, -72, -64, -59,  17, -80, -15,  45, -77,  33,  24,  13,  57, -38, -94, -77;
/M: SY='Q';  M=  21, -68, -65, -42, -88, -73,  13, -82,  64, -81,  -3,  37, -77,  68, -15, -21, -38, -40, -87, -74;
/M: SY='S';  M=  61,   1, -72, -69, -82, -61, -74, -74, -70, -47, -73, -62, -76, -64, -74,  81, -43, -14, -89, -77;
/M: SY='K';  M=  -8, -85, -39,  52, -86, -54, -66, -85,  82, -35, -74, -21, -72,  -5,   3, -39, -19, -77, -85, -76;
/M: SY='P';  M=  33, -53, -10,  -2, -84, -16,  21, -66,  10, -56, -73,  -5,  65, -37, -46,  19,   2, -10,  -9, -77;
/M: SY='A';  M=  85, -73,  -6,   4, -79, -32, -75, -78, -69, -79, -73, -66, -39, -64, -74,  31, -55, -66, -87, -80;
/M: SY='I';  M= -48, -87, -93, -90, -60, -47, -92, 103, -83, -44,  -3, -83, -42, -82, -17, -81, -68,  -8, -83, -67;
/M: SY='K';  M= -47, -85,  38, -14, -44, -79, -65,  31,  63, -20, -27,  17, -40,  13, -13, -10, -42, -17, -87, -72;
/M: SY='E';  M=  25, -85,  15,  83, -37, -77, -12, -85,  12, -42, -76, -64, -37, -12,  -2, -47, -12, -78, -88, -77;
/M: SY='L';  M=  34, -77, -89, -82, -18, -84, -27,  -8, -75,  77, -30, -86, -88, -77, -82, -71, -64, -27, -81, -64;
/I:         E1=0; IE=-250; DE=-250;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 42 in 42 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] TCP
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
42 sequences

CYCLD_ANTCI (Q9SBV9), CYCLD_ANTLN (Q9SBV6), CYCLD_ANTMA (O49250), 
DICH_ANTMA  (Q9SNW8), PCF1_ORYSJ  (O23875), PCF2_ORYSI  (A2YXQ1), 
PCF2_ORYSJ  (Q6ZBH6), PCF3_ORYSJ  (Q53PH2), PCF5_ORYSI  (A2WM14), 
PCF5_ORYSJ  (Q8LT07), PCF6_ORYSI  (A2XMN1), PCF6_ORYSJ  (Q10CE8), 
PCF7_ORYSI  (A2WV68), PCF7_ORYSJ  (Q8LT05), PCF8_ORYSI  (A2ZMR9), 
PCF8_ORYSJ  (Q2QM59), TB1_MAIZE   (Q93WI2), TB1_ORYSJ   (Q8LN68), 
TCP10_ARATH (O82277), TCP11_ARATH (Q9SJK7), TCP12_ARATH (A0AQW4), 
TCP13_ARATH (Q9S7W5), TCP14_ARATH (Q93Z00), TCP15_ARATH (Q9C9L2), 
TCP16_ARATH (Q9M1U4), TCP17_ARATH (Q9LEZ9), TCP18_ARATH (A1YKT1), 
TCP19_ARATH (Q9LT89), TCP1_ARATH  (Q9FYG7), TCP20_ARATH (Q9LSD5), 
TCP21_ARATH (Q9FTA2), TCP22_ARATH (Q9C7G4), TCP23_ARATH (Q9LQF0), 
TCP24_ARATH (Q9C758), TCP2_ARATH  (Q93V43), TCP3_ARATH  (Q9MAH8), 
TCP4_ARATH  (Q8LPR5), TCP5_ARATH  (Q9FME3), TCP6_ARATH  (Q9FLM6), 
TCP7_ARATH  (Q9FMX2), TCP8_ARATH  (Q9C518), TCP9_ARATH  (O64647)
» more

PDB
[Detailed view]
7 PDB

7VP1; 7VP2; 7VP3; 7VP4; 7VP5; 7VP6; 7VP7