PROSITE entry PS51497
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General information about the entry
| Entry name [info] | UMA |
| Accession [info] | PS51497 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2010 CREATED;
26-FEB-2020 DATA UPDATE; 08-NOV-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51497 |
| Associated ProRule [info] | PRU00830 |
Name and characterization of the entry
| Description [info] | UMA domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=48; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=44; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3741412; R2=0.0063080; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5720.6245117; R2=1.4007252; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=972; H_SCORE=7082; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=655; H_SCORE=6638; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-25; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='M'; M=-51,-57,-72,-64,-33,-70,-53, 17,-61, 63, 92,-66,-66,-54,-59,-61,-48, 12,-61,-40; /M: SY='D'; M=-49,-66, 92, 46,-72,-28, -8,-71,-38,-68,-64,-29,-51, 25,-46, 20,-43,-67,-79,-57; /M: SY='D'; M=-22,-66, 80,-38,-72, 74,-50,-75,-50,-72,-66,-31,-55,-48,-58,-39,-50,-70,-72,-62; /M: SY='V'; M=-43,-57,-72,-67,-40,-74,-73, 62,-64,-24,-27,-65,-65,-64,-66,-56,-40, 83,-70,-47; /M: SY='P'; M=-53,-78,-15, -3,-74,-56,-55,-62,-48,-71,-58,-57,120,-13,-60,-50,-47,-67,-67,-69; /M: SY='F'; M=-58,-58,-75,-70,108,-71,-58,-10,-66,-14,-35,-65,-72,-74,-64,-60,-51, 29,-34,-12; /M: SY='K'; M=-28,-60,-43, 36,-57,-60,-47,-21, 62,-34, 51,-42,-51,-11, 8,-42, 37, -1,-65,-51; /M: SY='I'; M=-52,-60,-72,-67, 11,-74,-63, 66,-65, 51, 28,-66,-66,-61,-65,-61,-33, 23,-59,-40; /M: SY='N'; M= 7,-56, 3,-47,-61, 28, 50,-39,-46,-60,-52, 55,-56,-42,-51, 55,-36, 3,-73,-52; /M: SY='P'; M=-18,-70, 27, 57,-70,-57,-49,-60, 6,-64,-57,-47, 86, -8,-16,-46,-46,-15,-68,-62; /M: SY='R'; M=-28,-65,-46, -7,-62,-19, 47,-62, 56,-47, 34,-39,-55, 26, 63, 1,-47,-59,-64,-48; /M: SY='F'; M=-33,-59,-70,-66, 85,-69,-50,-13,-63, 40,-30,-65,-23,-64,-61,-59,-52, -4,-36, 53; /M: SY='K'; M= 27,-10,-45, 23,-60,-29,-47,-54, 48, -2,-47,-43,-54, 33, 22, 15,-22,-24,-63,-53; /M: SY='P'; M= 7, 52,-49,-47,-62, -3,-52,-56, -6,-35,-52, 14, 61,-18, 10, 20, 36,-28,-69,-59; /M: SY='P'; M= -3,-64, 23,-41,-58,-54,-50, -9, 23,-54, 16, -4, 76,-12,-29, 8,-13, 1,-65, -3; /M: SY='P'; M= 2,-63, 24, -6,-62,-25,-46,-37,-41,-36,-53, 4, 60, 37, -1, 45,-21,-39,-66,-13; /M: SY='K'; M= 17, 8,-46, 2,-31, 9,-49,-31, 42,-31,-51, -8, 20, 4, 31, 16,-11,-54,-64,-54; /M: SY='V'; M=-41,-58,-13,-31, -5, 23, 8,-18, -7,-23,-10, -9,-59,-23,-52, 33,-16, 51, 1, 13; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='Y'; M=-63,-77,-37,-29, -2,-70, 0,-69,-58,-45,-62, -2,-74, 31,-26, 17, 24,-68, 5, 44; D=-21; /I: I=-21; DM=-53; /M: SY='Q'; M=-23,-68, 20, 14,-70, 8, 11,-62,-17,-63,-56,-29, 19, 62, -2, 0, 17,-15,-72,-58; D=-21; /I: I=-21; DM=-53; /M: SY='L'; M=-31,-57,-67,-61, 21,-69,-56, 14,-60, 63, 38,-24,-67, 1,-59,-57,-20, 23,-58,-39; /M: SY='P'; M=-34,-70, 27, 0,-46,-54,-51,-42,-45,-65,-56, 3, 99, 16,-54, -6, 13,-41,-69,-62; /I: I=-19; MD=-47; /M: SY='M'; M=-10,-71, 5,-66, 1,-40,-69, 28,-69, 8, 34,-66,-19,-36,-72,-18,-56, 19,-74,-56; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='G'; M=-30,-67, 17, -5,-61, 41, -1,-54,-50, 17,-49, 16,-63, 37,-10,-24,-53,-15,-71,-58; D=-19; /I: I=-19; DM=-47; /M: SY='F'; M= 21,-63,-67,-63, 32,-62,-59, 29,-60, 23, -1,-60,-67,-58,-26, 17,-13,-37, 27, 18; D=-19; /I: I=-19; DM=-47; /M: SY='T'; M=-19, 16,-19,-43,-29,-57, 46,-12, 17, 10,-41,-41,-24, 31, 9, 15, 49,-24,-68,-47; /M: SY='I'; M=-35,-60,-66,-60, 4,-69, 2, 48,-12, 44, 4,-60,-65,-30,-24,-28,-47, 25,-53, 36; /M: SY='K'; M=-49, 5,-42,-39,-57,-52,-44,-60, 58,-63,-53, 47, 55, -9, -2, -3, 26,-58,-61, 22; /M: SY='D'; M=-44,-61, 59, 15,-64,-51,-44,-62,-12,-40,-56, -5,-11,-36, 45, 44, 34,-57,-73,-55; /M: SY='P'; M=-22, 41,-59,-25, 1,-43,-55, 12,-54, 44,-32,-30, 47, 30,-57,-22,-15, 1,-62,-47; /M: SY='S'; M= 28,-57, 20,-16,-55,-18, -1,-37,-45, 9, -1,-12, 6, 16,-18, 49,-20,-30,-66,-23; /M: SY='Q'; M= -9,-63, 27, 60,-66,-33,-15,-64, -5,-62,-55,-37,-50, 60,-11, 29, 12,-59,-67,-24; /M: SY='I'; M= -8,-59,-22,-61, 14,-46,-61, 60,-60, 25,-11,-19,-31,-58,-62,-17,-15, 36,-60, -8; /I: I=-16; MD=-40; /M: SY='D'; M=-25,-63, 52, 49,-51,-43,-47,-16,-32, 30,-42, 4,-57,-23,-12,-34,-47, 5,-68,-14; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='K'; M=-23,-65, 7,-12,-61,-59,-14,-56, 32, 7,-17, -4, 2, 4, 25, 25, 2,-37,-71,-56; D=-16; /I: I=-16; DM=-40; /M: SY='E'; M= 26,-61, 21, 58,-66,-51,-15,-61, 0,-61,-55, 10, 3, 8, 21, 12,-16,-26,-69,-57; /M: SY='Y'; M=-27,-63,-56, 21, 33,-66,-41,-37,-32, 32, 5,-60,-34,-49,-53,-24,-37,-12,-37, 85; /M: SY='Q'; M=-50, 4, 35, 40,-68,-54, 32,-67, 9,-65,-56, 51,-55, 60,-15,-19, -4,-65, 20,-53; /M: SY='Y'; M=-59,-70,-59,-62, 11,-32, 11,-46,-54,-42,-39,-59,-71,-50,-52,-54,-55,-51,-18,124; /M: SY='D'; M=-49, -2, 89,-31,-66, -5,-21,-68,-43,-67,-63, 10,-56,-43, -4, 16, 26,-63,-79, -9; /M: SY='F'; M=-63, 2,-75,-71,109,-71,-54,-38,-66,-31,-40,-65,-74,-74,-64,-62,-56,-17, 31, 37; /M: SY='Q'; M= 8,-60, 6, -6,-62,-31, 26,-53,-39,-34,-49, -3,-55, 60, 7, 27, 37, -2,-71,-52; /M: SY='L'; M=-30,-58,-64,-56,-38,-69, 1,-25,-56, 65,-25,-60,-66, 24,-21,-54, 15, 28,-65,-45; /M: SY='E'; M=-48,-69,-21,103,-71,-31,-43,-68,-31,-64,-60,-46,-45,-24,-41,-46,-49,-27,-69,-62; /M: SY='R'; M=-42,-69,-45,-15,-64,-29, 41,-68, 25,-40,-52, 30, -8, 0, 86,-46,-51,-64,-68,-51; /M: SY='S'; M= 7,-17,-47,-22, -3,-31,-48,-58, -2,-45,-52,-16,-54, 44, 5, 63, 34,-52,-66,-51; /M: SY='V'; M= 34,-55,-66,-60,-46,-61,-65, 17,-59, -1, 30,-60,-63,-58,-62,-29, -5, 69,-70,-51; /M: SY='L'; M= 24,-59,-65,-54,-10,-63,-56, 10,-57, 60,-27,-62, -9, 37,-57,-52,-49, -3,-61,-45; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 15 in 15 different sequences |
| Number of true positive hits | 15 in 15 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | UMA |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
15 sequences
MB12A_BOVIN (Q3T0N1), MB12A_CHICK (Q5ZJX7), MB12A_DANRE (Q7SXX7), MB12A_HUMAN (Q96EY5), MB12A_MOUSE (Q78HU3), MB12A_RAT (Q6P777), MB12A_XENLA (Q7ZYJ7), MB12B_HUMAN (Q9H7P6), MB12B_MOUSE (Q6KAU4), UBA1L_HUMAN (F5GYI3), UBAP1_DANRE (F6P6X0), UBAP1_HUMAN (Q9NZ09), UBAP1_MOUSE (Q8BH48), UBAP1_RAT (Q5XIS7), UMAD1_HUMAN (C9J7I0)» more
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| PDB [Detailed view] |
1 PDB
6VME |