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| Entry: PS51504 |
General information about the entry
| Entry name [info] | H15 |
| Accession [info] | PS51504 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2010 CREATED;
10-MAY-2017 DATA UPDATE; 11-DEC-2019 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51504 |
| Associated ProRule [info] | PRU00837 |
Name and characterization of the entry
| Description [info] | Linker histone H1/H5 globular (H15) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=73; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=73; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1323326; R2=0.0084606; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7660.1591797; R2=2.9217172; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1120; H_SCORE=10932; N_SCORE=11.6; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=517; H_SCORE=9171; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-48; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='S'; M= -2,-154, 11, -55, -75, -27, -41, -43, 14, -34, -52, 17, 20, 10, 13, 46, 19, -81,-161, -51; /M: SY='H'; M= -71, -14, -69, -74, -69, 4, 100, -49, 29, -24,-140, 19, 10, -35, -19, -12, 14, -52, -27,-137; /M: SY='P'; M= -48,-160, -48, -74, -73, -28, -26, -57, 11, -24, -33,-144, 98, -47, -77, 9, -2, -6,-158, -30; /M: SY='P'; M= -16,-154, 4, -49, -66, -57, -44, -59, 18, -92,-147, 17, 64,-135, 16, 46, 31, -54,-162,-149; /M: SY='Y'; M= -15, -76, -83, -66, -16,-157,-136, -23, -38, 15, 14,-151,-158, -65, -47, -84, 15, 13, 52, 98; /M: SY='S'; M= 1, -59, 18, -1, -28, -51, -58, -52, 4, 25, 25, 0, -33, -3, -2, 33, -59, -27,-156, -14; /M: SY='D'; M= -22,-156, 52, 45, -93, -93, -56, -72, 19,-103,-147, -22, -9, 35, -30, 12, 13, -4, -4, -58; /M: SY='M'; M= -34,-149,-156, -77, -67,-100, -30, -7, 15, 30, 126, -80,-151,-138, -58,-147, -69, -22, 8, -24; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='I'; M= -23, -2,-161,-157,-130,-100, -12, 86,-154, 1, 2,-153,-154,-151,-156, -43,-135, 58,-157,-137; /M: SY='K'; M= -26, -18, -34, -16, 3, -46, -14, 14, 37, 37, 30, -60, -26, -19, -43, -66, 12, 8,-150, -13; /M: SY='E'; M= 21,-154, 33, 84,-156,-100,-135, -71, -15, -94, -28, -8, -19, 4, 8, -31, -32, -48,-158, -45; /M: SY='A'; M= 98, -4,-145, -68,-149, -42,-146, -87, -77, -95,-139,-140,-146,-138,-145, -7, -47, -34,-153, -9; /M: SY='I'; M=-142,-153,-161, -74, -11,-165,-155, 89,-154, 33, 31,-155, -15, -23,-155,-150,-137, 26,-151,-133; /M: SY='E'; M= 4, -15, -38, 36,-106, -71, -39, -25, 35, -16, -31, -16, -51, 11, 11, 27, 26, -5, -8, -57; /M: SY='A'; M= 54, -50, 32, 29,-153, -4, -19, -81, 0,-148, -50, -24,-143, -3, -41, 25, 24, -27,-159, -72; /M: SY='L'; M= -52, 28, -84, -47,-127,-156, -18, 0, -35, 79, 37, -17,-156, -20, -54, -9, -49, -79,-153,-134; /M: SY='K'; M= -19, -19, 20, -2, -81, 15, -28,-154, 68,-155, -49, 61, 12, -17, -30, -13, -87, -56,-158, -61; /M: SY='E'; M= -69,-155, 66, 78,-157, -41, -39,-156, -39, -52,-149, 22, -21, -8, -49, 18, -11,-106, -19,-147; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='R'; M= -60, 3, -52, 10, -74, -7, 4, -73, 47,-154,-144, -2, 57, -52, 77, -54,-138, -84,-155, -48; /M: SY='K'; M= -38,-151, -17, -2, -47, 27, -54, -67, 66, -93,-143, 48, -16, -6, -49, 17, 9, -27,-156, -72; /M: SY='G'; M=-129,-154, -62, -27, -43, 101,-147, -93, -82, -72, -46, -53,-147,-143, -75, -73, -44, -79, 27, -54; /M: SY='S'; M= 37, 41,-143,-141,-145,-136,-144, -21,-140, -45, -2, -49, -50,-135, -44, 84, -40, 31,-160,-144; /M: SY='S'; M= -75, -43, 8,-133,-150,-131, -11, -35,-134,-151,-145, 22,-142,-129,-139, 102, 39,-141,-162, -68; /M: SY='R'; M= -21,-151,-147, -19, -7, -93,-141, 3, 24, 34, 30, -79, -24, -7, 46, -22, -31, 27,-150, -13; /M: SY='Q'; M= 21,-151, 9, -49, -18, -69, -22, -36, 25, -34, -54, -10, 20, 73, -15, -3, 4, -5,-151, 0; /M: SY='A'; M= 80,-143, -25, -26, -74, -76,-141, -44, 17, -69, -3, -11,-143, -16, -45, 31, 0, -88,-155,-145; /M: SY='I'; M= -76,-153,-163,-160,-125,-166,-160, 107,-156, 24,-112,-155,-153,-152,-158,-151,-136, -6, -8,-133; /M: SY='K'; M= 15, -13,-103, 16, -6, -86, -53, -15, 64, -11, 1, -45,-146, -20, 29, 19, -78, -19, -17, -20; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='K'; M= -16,-152, -47, 0, -63,-101, 21, -89, 88, -91, -25, 25, -68, -37, 24, -12, 9, -65,-155,-141; /M: SY='Y'; M= -15,-156, -76,-149, 65,-153, 35,-101, -73, -49,-130, -64, -39,-142, -37,-143, -76, -55, 71, 114; /M: SY='I'; M=-140,-150,-161,-156, -67,-163,-154, 85, -48, 36, 42, -60,-154,-149, -76,-149,-135, 47,-153,-134; /M: SY='E'; M= 2, -21, -33, 57, -27, -22, -47, -51, 43, -14, -34, -35,-143, 48, 4, -1, -18, -48, -19, -59; /M: SY='S'; M= 35, -44, 40, 40, -55, -21, -4,-151, 5, -98,-144, -42, -73, 42, -17, 42, 1, -86,-158,-144; /M: SY='N'; M= -21,-151, -32, -27, -70, -49, 51, -74, 62,-151,-141, 69, -80, 11, 31, -24, 17,-149,-156, -3; /M: SY='Y'; M= -49, -42, -78,-144, 28, 3, 72, -68, -72, -51,-133, 34, -38, -24, -49, -41, -27, -68, 49, 101; /M: SY='P'; M= -55, -45, 7, 7, -49, 22, 26, -84, 49, -95,-142, -2, 52, -3, 11, -23, -28, -38, 0, 28; /M: SY='V'; M= -6, -42, 34, -8, -64, 10, -8, 6, -25, -7, -52, -23, -43, -20, -46, -11, 16, 46, -37, 0; /I: I=-5; MD=-11; /M: SY='V'; M= -88,-162, -11, -27,-153, -14, -13, -35, 11, 14, -47, 5, -65, -20, -68, 7, -11, 22, -38, -58; D=-5; /I: I=-5; MI=0; MD=-11; IM=0; DM=-11; /M: SY='D'; M= -54,-170, 49, -45, -28, -45, -32, -79, -54, -23,-158, 14, -7, -37, -10, -12, 10, -41,-178, -62; D=-5; /I: I=-5; DM=-11; /M: SY='P'; M= -26,-161, -14, 19,-158, -42, -48, -16, -1, -84, 23, -14, 64, 35, -61, -3, -1, -5,-164,-152; D=-5; /I: I=-5; DM=-11; /M: SY='P'; M= 24,-154, 18, 6, -37, -39, -45,-149, 28,-152,-146, 9, 47, 8, -35, 18, 13, -22, 5, -51; D=-5; /I: I=-5; DM=-11; /M: SY='N'; M= -14,-152, 12, -48, 1, -47, -1, -37, 29, -45, 21, 62, -9, 5, 34, -8, 5, -75, -7, -35; D=-5; /I: I=-5; DM=-11; /M: SY='F'; M= -49, -49, -32, -57, 73, -86, 59, -5, -31, 21, 1, 17,-154, 10, -7, -36, -29, 1,-143, -23; /M: SY='K'; M= -10,-152, 20, -4,-152, -27, -9, -33, 55, -67, 20, 26, -6, -10, 41, 13, -14, -31,-157,-143; /M: SY='S'; M= 10,-150, -43, -48, -32, -72, 32,-143, 30, -20,-138, 15, 23, -6, 12, 43, 20, -28,-152, 23; /M: SY='H'; M= -26,-151,-148, -65, 42, -95, 60, -35, -33, 43, 43, -23,-154, 29, 27, -28,-100, -3,-147, -17; /M: SY='L'; M= -33, -34,-162,-156, 35,-162,-150, 36,-155, 70, -9,-157,-159,-152,-154,-150, -70, 35,-147, -46; /M: SY='K'; M= -33,-152, -71, -76, -42, -57, -55, -87, 71, -53, -50, 43, -80, -21, 54, 19, 15,-147, -10, -16; /M: SY='R'; M= -12,-151,-138, -59, -70, -59, 25, -50, 45, -1, 9, 8, -30, 22, 45, 29, 15, -55,-154, -18; /M: SY='A'; M= 75, 0, -72, -69, -70, -70, 49, -37, -20, -70, -56, -36,-147, 20, -55, 10, -1, -25,-154, 4; /M: SY='L'; M= -53,-149,-162,-156, -39,-163,-150, 45,-155, 79, 9, -70, -62,-150,-154,-152,-139, 17,-151, -61; /M: SY='K'; M= -29, -21, -43, 9,-152, -42, -39, -60, 85, -32,-141, 18, -65, -1, 43, -55, -57, -84,-154, -48; /M: SY='K'; M= -13, -55, -28, -39, -76, -36, 16, -56, 66, -76,-142, -26, -81, -5, 65, 28, -31, -57,-154, -35; /M: SY='G'; M= 45, 24, -71, -56, -56, 53, 0, -51, -56, 42, 40,-141,-151, -64, -78, -50,-139,-134,-154,-142; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='V'; M= -1, 14,-155, -54, -60,-157, -16, 20, -14, 8, 12, -78,-155,-146, -22, -59, -21, 78,-160,-139; /M: SY='E'; M= 31,-152, 17, 61, -80, -70, -40, -70, 31, -40, -31, 8,-143, 8, -37, 22, -73, -21,-159,-146; /M: SY='N'; M= 5,-150, 2, 21,-155, -68, 8, -94, 41, -70,-144, 49,-145, 9, 10, 42, 16, -61,-161,-145; /M: SY='G'; M=-132,-156, -40, -2,-161, 93, -43, -81, 24,-163,-152, 1,-147,-138, -33, -82, -75,-160,-155,-154; /M: SY='K'; M= -58,-155, 18, 12, -27,-152,-140, -16, 46, 6, -26,-136,-149, 23, 34, -8, 11, 1, -13, -23; /M: SY='L'; M= -63,-151, -71,-157, 42, -85,-153, 49,-157, 67, -36,-158, -49,-153,-156, -53,-141, 11,-148,-129; /M: SY='V'; M= -16,-153,-145, 24,-140,-156, -1, 39, 9, -7, -10, -24, -41, 27, -54, -65, -20, 51, -20, -35; /M: SY='Q'; M= -56, -24, -43,-125, -18,-151, 1,-151, 61, -38, 12, -65,-104, 91, 46, -51,-141, -92,-153, -48; /I: I=-11; MD=-28; /M: SY='P'; M= -31, -72, -88,-148,-152,-156, -41, -5, 7, -96, -55, -15, 51,-149,-150, -7, 50, 49,-170,-153; D=-11; /I: I=-11; MD=-28; /M: SY='K'; M= -62, -63,-151, -80,-172,-161,-154,-171, 73,-171,-161, -5, -35, -60, 11, 15, 13,-166,-173,-162; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='A'; M= 28, -59, -24, -17, -6, -10,-164, -61,-160, 1, -8, -85, 12, -62, -22, -53, -44, -73,-172,-160; D=-11; /I: I=-11; DM=-28; /M: SY='S'; M= -13,-158, -23, -28,-164, 24,-146, -80, -22, -93, -34, 44,-155, 11, -9, 50, -2, -82,-169,-157; D=-11; /I: I=-11; DM=-28; /M: SY='G'; M= -57, -53, -26, -31,-159, 81, 1, -93, 11, -52,-149, 38, -44, -12, -2,-132, -71, -87,-158,-152; /M: SY='S'; M= -84, -6,-140, -81, -21,-142, -53, -53, 9, -6, -22, 8, -40, -66, 39, 78, 8, -64,-158, -59; /M: SY='Y'; M= -59,-155,-158, -71, 86,-160,-134, -38,-151, -69, -49,-154,-163,-152,-150, -70, -79, 17,-120, 104; /M: SY='K'; M= -44,-157,-141, -85,-153, -50, -49, -38, 84, -41, 27,-134,-148, 5, 61, -91, -14, -46,-155,-143; /M: SY='L'; M= -69,-152,-161, -62, -2,-164,-150, 43, -24, 72, 8,-158, -46, -63, -52,-153,-141, 0,-151, -47; /M: SY='P'; M= 27, -59, -48, -62,-154, 13, -14,-146, 5, -65, -14, 45, 46,-136, -44, 40, -4, -8,-162,-150; /M: SY='P'; M= 34,-156, -10, 5, -64, -45, -10,-151, 52, -96, -39, -22, 57, -30, -39, -4, -17, -37,-159, -67; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 160 in 148 different sequences |
| Number of true positive hits | 160 in 148 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 99.38 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Feature key [info] | DOMAIN |
| Feature description [info] | H15 |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
148 sequences
B4_XENLA (P15308 ), H101_CHICK (P08284 ), H103_CHICK (P08285 ), H10A_XENLA (P22845 ), H10B_XENLA (P22844 ), H10_BOVIN (Q0IIJ2 ), H10_HUMAN (P07305 ), H10_MOUSE (P10922 ), H10_PONAB (Q5NVN9 ), H10_RAT (P43278 ), H10_XENTR (Q6NVM0 ), H110_CHICK (P08286 ), H11E_PARAN (Q99281 ), H11L_CHICK (P08287 ), H11R_CHICK (P08288 ), H11_ARATH (P26568 ), H11_BOVIN (G3N131 ), H11_DROVI (Q24704 ), H11_GLYBA (P40263 ), H11_GLYSA (P40266 ), H11_HUMAN (Q02539 ), H11_MOUSE (P43275 ), H11_RAT (D4A3K5 ), H11_VOLCA (Q08864 ), H11_WHEAT (P15871 ), H12E_PARAN (Q99282 ), H12_ARATH (P26569 ), H12_BOVIN (P02253 ), H12_CAEEL (P15796 ), H12_DROVI (Q94555 ), H12_GLYBA (P40264 ), H12_HUMAN (P16403 ), H12_MOUSE (P15864 ), H12_VOLCA (Q08865 ), H13E_PARAN (Q99283 ), H13_BOVIN (A7MAZ5 ), H13_CAEEL (Q19743 ), H13_DROVI (Q94972 ), H13_GLYBA (P40265 ), H13_HUMAN (P16402 ), H13_MOUSE (P43277 ), H13_RABIT (P02251 ), H14_CAEEL (O17536 ), H14_HUMAN (P10412 ), H14_MOUSE (P43274 ), H14_RABIT (P02252 ), H14_RAT (P15865 ), H15_CAEEL (O01833 ), H15_HUMAN (P16401 ), H15_MOUSE (P43276 ), H15_RAT (D3ZBN0 ), H16_CAEEL (O16277 ), H1A_CHITE (P40275 ), H1A_OLILU (P82898 ), H1A_PLADU (P06894 ), H1A_XENLA (P06892 ), H1B_CHITE (P40276 ), H1B_OLILU (P82899 ), H1B_PLADU (P06895 ), H1B_STRPU (P15869 ), H1B_XENLA (P06893 ), H1C1_XENLA (P15866 ), H1C2_XENLA (P15867 ), H1C_CHITE (P40277 ), H1D_STRPU (P15870 ), H1E_CHIPA (P40262 ), H1E_CHITE (P40278 ), H1E_STRPU (P19375 ), H1FOO_BOVIN (Q3HNG7 ), H1FOO_HUMAN (Q8IZA3 ), H1FOO_MOUSE (Q8VIK3 ), H1G_STRPU (P07796 ), H1L1_OSTED (Q86QH9 ), H1L2_OSTED (Q86QI0 ), H1L5_ENSMI (P27203 ), H1L_MYTCA (P22974 ), H1L_MYTTR (Q05831 ), H1L_SPISO (P22975 ), H1O_CHITH (Q07134 ), H1S_SPHGR (Q99284 ), H1T_HUMAN (P22492 ), H1T_MACMU (P40286 ), H1T_MOUSE (Q07133 ), H1T_PIG (P06348 ), H1T_RAT (P06349 ), H1X_CAEEL (Q18336 ), H1X_HUMAN (Q92522 ), H1_ANAPL (P09426 ), H1_ASCIM (Q9UV33 ), H1_ASHGO (Q75C22 ), H1_CANGA (Q6FJX6 ), H1_CHICK (P09987 ), H1_CHITH (P21895 ), H1_DICDI (P54671 ), H1_DROHY (P17268 ), H1_DROME (P02255 ), H1_ECHCR (P02257 ), H1_EMENI (Q9P8F8 ), H1_EUPES (Q9M5W4 ), H1_LYTPI (P06144 ), H1_MAIZE (P23444 ), H1_NEUCR (Q8J0U2 ), H1_ONCMY (P06350 ), H1_PARAN (P02256 ), H1_PEA (P08283 ), H1_PSAMI (P15868 ), H1_SALSA (P84408 ), H1_SALTR (P02254 ), H1_SOLLC (P37218 ), H1_SOLPN (P40267 ), H1_TIGCA (P35060 ), H1_WHEAT (P27806 ), H1_YEAST (P53551 ), H24_CAEEL (P10771 ), H5_ANSAN (P02258 ), H5_CAIMO (P06513 ), H5_CHICK (P02259 ), HILS1_HUMAN (P60008 ), HILS1_RAT (D3ZZW6 ), HMGYA_ARATH (Q43386 ), HMGYA_MAIZE (Q9FYS5 ), HMGYA_SOYBN (Q00423 ), HMGYB_SOYBN (Q10370 ), HP1B3_BOVIN (Q08DU9 ), HP1B3_CHICK (Q5ZM33 ), HP1B3_HUMAN (Q5SSJ5 ), HP1B3_MOUSE (Q3TEA8 ), HP1B3_RAT (Q6P747 ), HSPL_MULSU (Q08GK9 ), KAT6A_HUMAN (Q92794 ), KAT6A_MOUSE (Q8BZ21 ), KAT6A_RAT (Q5TKR9 ), KAT6B_HUMAN (Q8WYB5 ), KAT6B_MACFA (Q8WML3 ), KAT6B_MOUSE (Q8BRB7 ), SHPRH_HUMAN (Q149N8 ), SHPRH_MOUSE (Q7TPQ3 ), SMH1_MAIZE (Q6WS85 ), SMH2_MAIZE (B4FT40 ), SMH3_MAIZE (Q6WLH4 ), SMH4_MAIZE (Q8W119 ), SMH5_MAIZE (Q6WLH3 ), SMH6_MAIZE (C0HIA3 ), TRB1_ARATH (Q8VWK4 ), TRB2_ARATH (Q9FJW5 ), TRB3_ARATH (Q9M2X3 ), TRB4_ARATH (F4I7L1 ), TRB5_ARATH (F4IEY4 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
HILS1_MOUSE (Q9QYL0 ) |
| PDB [Detailed view] |
13 PDB
1GHC; 1HST; 1UHM; 1USS; 1UST; 1YQA; 2LSO; 2RQP; 4QLC; 5NL0; 5WCU; 6N88; 6N89 » more |
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission