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PROSITE entry PS51511


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General information about the entry

Entry name [info] FIP_RBD
Accession [info] PS51511
Entry type [info] MATRIX
Date [info] 01-NOV-2010 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51511
Associated ProRule [info] PRU00844

Name and characterization of the entry

Description [info] FIP-RBD domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=63;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=58;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3604796; R2=0.0055957; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7712.3823242; R2=3.8209417; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1098; H_SCORE=11908; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=740; H_SCORE=10540; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='H';  M=-31,-43,-30, -3, 22,-41, 42,  0, 24, -1,-26, 23,-41,  5,-26,  9, 27,  4,-47,-25;
/M: SY='Q';  M=  2,-45,  3, 13,-42, -6,-32,-30,  3,  0, 21,  2, 18, 37,  4, -6,  2,  2,-50,-37;
/M: SY='E';  M=-10,-48,-25, 43,-39, 18,-30,-42,  0, -3,-33,-29, 18, 20, 20, -2,  1,-39,-43, 13;
/M: SY='G';  M= 22,-42,-32, -8,-40, 27, 15, -3,-30, -9,  8, 25,-41,  6, -6, 18,-26,  7,-51,-36;
/M: SY='Q';  M= -8,-46,-30, 11,-40,  5,-30,-35, -3,  0,-30,-27, 12, 56,-10, 37,-25,-10,-45,  4;
/M: SY='P';  M=-33,-48,-36, -6,  2, -5,  1,-13, 15,  8,-28,-32, 47,-27, 28, 13, -4,-34,-40, 21;
/M: SY='D';  M=  1,-44, 46, 17,-39,-37, 15, -1,-27, 12,-29, 34,-42,-25,  2, 12,-26,-10,-56,-35;
/M: SY='Q';  M= 26,-45, -6, -3,-36,-40,-33, 14, -1, 23, 22,-34, 11, 54,-30,-29,-31,-23,-46,-34;
/M: SY='Q';  M= 19,-46, 26, 15,-46,-37,-30, -9,-22,-36, 12, 12, 10, 42, 20, -2,-27,  8,-53,-38;
/M: SY='G';  M= 19,-43,-33, -5,-45, 39,-33,-39,  1,-14, 30,-25,-38, 35, -6, 26, -1,-36,-48,-38;
/M: SY='D';  M= -5,-48, 37, 12,-49,-38, 15, -9, 28,-44,-37,-22, 36, 24,  6, 14,  7,-38,-53,-38;
/M: SY='Y';  M= 11,-46, 27, -1,-29,-38, 17, -4,-29,-23,-29,  4,  9, 36,-32, -4, 12,-11,-38, 49;
/M: SY='D';  M= 26,-46, 32, 30,-45,-35,-29,-40, 12,-43,-37, 13, 28, 27,-27, -4,-27, -9,-48,  7;
/M: SY='S';  M= 17,-43,-28, 12,-45, -2, 46,-44,-26,-16,-34,-23, 11, 16,  2, 54,-22,-39,-52,-35;
/M: SY='W';  M=-32,-45,-38, -3,-26,-41,-37,-24, -4, 42,-20,  8, 20,-31,-36, 26, -2,-28, 80,-27;
/M: SY='T';  M= 43,-39, -1, 22,-42,-34, 27, -2,-30,-34,-31,  9,-37,-28,-36,-18, 43,  7,-55,-37;
/M: SY='H';  M= 32,-42, 30,-25,-40,-30, 48,-15,-27,-41,-34, 18,-40, -4,  2, 33,  7,-34,-51, 12;
/M: SY='E';  M=-31,-51, 43, 76,-52,-41,-26,-50,-18,-25,-42,-23,  4, 19,-27, 15,-28,-46,-54,-42;
/M: SY='L';  M=-14,-46, 24, 31,-29,-48, 14, 26, -4, 42,-17,-34,-43,-28,-35,-10,-31,-19,-49,-31;
/M: SY='M';  M=  0,-45, 31, 18,-32,-41,-27, -1,-27, 17, 39, 23,-42, 20,  2,-29, -3,-27,-46, 13;
/M: SY='D';  M= -6,-45, 26,  4, -5, 17,-33, 14,-30,  3, 20,  4,-41, 19, -6, -5, 14,-27,-49,-33;
/M: SY='M';  M= 41, 22,-39, -7, -5,-10,-34,-28,  2,-26, 65,-33,-41, 14,  3, -2,-28, -3,-46,-32;
/M: SY='S';  M=-25, 30, 15,-32,-35,-34,-34, -1,-33, 14,-27, 27,-42,-30,-38, 51, 25, -2,-56,-36;
/M: SY='K';  M= -6,-44,-34,  3,-37,-44,-34,  1, 41, 12,-24,-30,-40, 29, 17, -6, 16, 10,-48,-34;
/M: SY='D';  M= -4,-45, 55, 35,-43,-39, 25,-38,-26, 10,-32, 14,-38, 14,-32, -4, 18,-37,-58,-36;
/M: SY='Q';  M=-31,-50, 31, 55,-55,-39,-24,-51, 30,-48,-40, 12,-34, 60,-17,  2, -3,-47,-52,-39;
/M: SY='L';  M=-35,-43,-47,-37,-22,-53,-36, -9,-32, 57, 20,-43,-50, 32, 18,-39, -6, 20,-46,-28;
/M: SY='Q';  M=-33,-48,-32, 30, -6,-49,-32, 28, 20,  2, 35,-34,-41, 50,  7,-33,-31,  9,-45,-30;
/M: SY='E';  M=-30,-47, 20, 49,-46,-39,-27,-14,  8,-15,-35, 17,-36, 20, 23, 25,  3,-38,-53,-38;
/M: SY='A';  M= 48,-41, 27, 44,-46,-34,-33,-38, -4,-17, 19,-28,-36,-22, -6,-21,  5,-32,-51,-40;
/M: SY='L';  M=-38,-42,-13,-46, 18,-57,-43, 27,-48, 65, -5,-50,-53,-44,-47,-46,-33, 16,-42,-23;
/M: SY='Q';  M=-29,-49,-24, 14,-52,-37,-24,-50, 49,-47,-36, 12,-37, 66, 32, 27,-26,-46,-48,-36;
/M: SY='K';  M=-34,-51, 20, 48,-44,-44, 17,-44, 50,-43,-36,-24,-36, 29, 24,-29,-32,-12,-45, 12;
/M: SY='Q';  M=-32,-51,-27, 18,-50,-43,-25,-38, 45,-38, 18,-25,-38, 80, 28,-27,-32, -4,-46,-34;
/M: SY='E';  M=-15,-51, 41, 67,-55,-42,-26,-54, 45,-49,-42,-21,-32, 29,-15,-27,-31,-48,-52,-41;
/M: SY='E';  M=-32,-50, 14, 68,  5, -1,-28,-15,-20,-15,-35,-28,-36, 16,  7, -1,-32,-39,-43,  7;
/M: SY='D';  M=-11, 18, 39, 34,-42,-44, 21, -6,  2,-11, 12,-26,-39, 16,  4,-28,  8,  7,-55,-35;
/M: SY='N';  M=-12,-40,-19,-32,-40,-30,-24, -1,  3,-35, 20, 89,-45,-26,-30,-22,-21, 22,-61,-39;
/M: SY='R';  M= 10,-47, -4, 21, -3,-41,-29,-38, 32,-19,-32,-27,-40, 44, 44, -7,-30, -5,-46,-33;
/M: SY='R';  M=-17,-52, 27, 46,  3,-44,-25,-50,  7,-44,-38,-25,-39, 44, 62,-29,-34,-46,-47,-33;
/M: SY='L';  M=-38,-41,-56,-48,-14,-56,-38, -4,-48, 74, 56,-53,-54,-40,-45,-48,-34,-12,-43,-25;
/M: SY='R';  M=-35,-54,-21, 51,-53,-46,-24,-53, 17,-47,-37,-26,-38, 54, 72,-29,-35,-48,-48,-37;
/M: SY='Q';  M=  6, 18, 39, 11,-48, 10, 31,-38, -3,-41,-35,-22,-39, 41,-29,  0, 11,  6,-56,-37;
/M: SY='Y';  M=-43,-53,-43,-46, 32,-50,-10,-28,-38,-24,-22,-44,-55,-34,-35,-38,-37,-33,  0,116;
/M: SY='I';  M= -2,-44,-55,-50,-21,-54,-48, 68,-47, 28, 45,-48,-47,-43,-49,-41,-30, 26,-47,-28;
/M: SY='D';  M=-38,-50, 96, 10,-57,-34,-23,-56,-25,-56,-52, 48,-39,-24,-33,-25,-27,-54,-73,-43;
/M: SY='S';  M=-26,-41,  2,-28,-44,  6,-29,-42,  1,-16,-35, 33,-39,-23, 39, 40, 39,-37,-54,-38;
/M: SY='I';  M=-37,-44,-57,-52,-16,-60,-48, 63,-50, 56, -4,-52,-51,-45,-50,-47,-32, 14,-45,-27;
/M: SY='L';  M=-38,-43,-57,-50,-14,-59,-43, 41,-50, 71, -1,-54,-54,-43,-48,-48,-34, -6,-43,-26;
/M: SY='M';  M=  1,-40,-44,-35,-27,-43,-36,-12,-36, 38, 50,-37,-45, 36,-36, 16, -1, 26,-48,-30;
/M: SY='R';  M=-10,-46,-30,-25,-44,-41,-28, -9, 23,-37,-30, 37,-43, 36, 58,-26,  3, 16,-51,-36;
/M: SY='I';  M=-31,-44,-57,-53,-23,-60,-58, 73,-49, -7,-10,-49,-48,-48,-52,-42,-27, 61,-51,-31;
/M: SY='M';  M= -1, 33,-54,-47,-23,-50,-39, 34,-43, 22, 88,-45,-47,-39,-44,-40,-30, 30,-49,-28;
/M: SY='E';  M=-33,-53, 35, 93,-56,-46,-25,-57,-14,-49,-46,-25,-28, -8,-24,-28,-32,-49,-54,-45;
/M: SY='H';  M=-36, 28,-22, 24,-46,-41, 87,-52, 25,-45,-34, 28,-40, 16, 33,-27, -2,-48,-59,-27;
/M: SY='H';  M= -5, 38, 21,-26,-35,-35, 54,-40,  1,-41,-34, 47,-42, 12,-29,  0, 22,-18,-48, 34;
/M: SY='P';  M=-38,-64,-39,-27,-58,-40,-42,-46,-35,-56,-42,-45,117,-38,-47,-35,-31,-51,-51,-55;
/M: SY='Q';  M=  8,-43, 15, 27,-50,-33,-27,-45,-19,-45,-37, 14,-36, 56,  5, 34, 29,-39,-53,-38;
/M: SY='I';  M=-38,-45,-57,-52,-16,-60,-47, 62,-50, 60, -3,-52,-51,-45,-50,-48,-33, -1,-44,-26;
/M: SY='L';  M=-39,-41,-56,-48,-12,-58,-40, -4,-50, 79,  0,-56,-56,-42,-47,-49,-35,-11,-43,-25;
/M: SY='E';  M= -6,-52, -9, 84,-55,-44,-25,-53,-12,-47,-40,-28,-30, 48, 10,-26,-32,-47,-50,-42;
/M: SY='I';  M= -5,-43,-42,-41,-29,-46,-44, 59,-39,-16,-16, 21,-45, 16,-42, -1,-25, 47,-52,-33;
/M: SY='P';  M=-11,-48,-36,-26,-44,-14,-37, -1, 53,-36, 20,-30, 58,-25,  8,-29, 11,  0,-48,-39;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 17 in 17 different sequences
Number of true positive hits 17 in 17 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info]
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] FIP-RBD
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
17 sequences

RB6I2_HUMAN (Q8IUD2), RB6I2_MOUSE (Q99MI1), RFIP1_HUMAN (Q6WKZ4), 
RFIP1_MOUSE (Q9D620), RFIP1_RAT   (Q3B7T9), RFIP2_HUMAN (Q7L804), 
RFIP2_MOUSE (G3XA57), RFIP3_DANRE (Q7T005), RFIP3_HUMAN (O75154), 
RFIP3_MOUSE (Q8CHD8), RFIP4_HUMAN (Q86YS3), RFIP4_MOUSE (Q8BQP8), 
RFIP4_XENTR (A4IIE8), RFIP5_HUMAN (Q9BXF6), RFIP5_MOUSE (Q8R361), 
RFP4A_DANRE (Q3LGD4), RFP4B_DANRE (B3DGU2)
» more

PDB
[Detailed view]
12 PDB

2D7C; 2GZD; 2GZH; 2HV8; 2K6S; 3TSO; 4C4P; 4D0G; 4D0M; 4UJ3; 4UJ4; 6S8X