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PROSITE entry PS51590


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General information about the entry

Entry name [info] SAM_MT_MNV_L
Accession [info] PS51590
Entry type [info] MATRIX
Date [info] 01-NOV-2011 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU00923

Name and characterization of the entry

Description [info] Mononegavirus L protein 2'-O-ribose methyltransferase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=203;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=198;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4956477; R2=0.0080915; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=19654.6816406; R2=11.0468626; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=743; H_SCORE=27863; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=495; H_SCORE=25123; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-35; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='R';  M= -66, -82, -63, -51, -72, -76, -53, -75,  16,  -6, -59, -57, -74,  25, 106, -61, -65, -72, -75, -62;
/M: SY='F';  M=   1, -73, -77, -71,  64,  -5, -64,   0, -63,  25,  36, -70,  13, -67,  29, -65, -62,  -4, -60,  17;
/M: SY='N';  M= -61, -71, -62, -67,   4,  -9, -65,  62,  10,  -9, -49,  62, -71, -63, -64, -56,  32,  -1, -77, -59;
/M: SY='G';  M= -54, -76, -64, -61,  47,  75, -63, -76, -60, -70, -65, -53, -70,  71, -64,   8, -63, -75, -66, -57;
/M: SY='V';  M= -61, -71, -82, -77, -45, -83, -74,  40, -74,  46, -39, -77, -78, -72, -75, -68,   8,  57,  57,  25;
/M: SY='P';  M=  30, -71, -62, -61,  47, -63, -63, -57,  10, -63, -60,  51,  60, -62, -62,   1, -53,  21, -72, -57;
/M: SY='S';  M= -45, -63, -56, -58, -71, -56, -62, -67, -57, -71, -66, -45, -62, -53, -63,  88,  77, -59, -85, -66;
/M: SY='S';  M= -46, -67, -55, -58, -75,  32, -60, -75,  11, -77, -70,  22, -64, -52, -59,  84,  29, -68, -81, -68;
/M: SY='S';  M=  58, -63, -63, -60, -70, -55, -63, -61, -60, -61,  60, -54, -65, -55, -64,  63,  43, -54, -79, -65;
/M: SY='H';  M= -63,  78, -70, -69, -60,  29,  98,   1, -68,  -4,  39, -59, -75, -63, -68, -63, -67, -64,  91, -49;
/M: SY='Y';  M= -70,  77, -74, -76,  28, -78, -45, -57, -69, -15, -51, -72, -85, -66, -67, -67, -65, -60, -36, 119;
/M: SY='K';  M= -63, -77, -57, -44, -75, -71, -60,   7, 106, -72, -62, -50, -64, -42, -26, -58, -57, -66, -72, -65;
/M: SY='W';  M=  40, -72, -75, -70, -51,  -6,  45,  23, -69,  35,  30, -69, -74, -64, -70, -61, -61,  -6,  64,  29;
/M: SY='S';  M= -55, -72,   9, -56, -60, -66, -58,   1,   0,   6,  39, -55, -70,  30,  28,  59, -51,  -4, -72,  23;
/M: SY='E';  M=  -8, -72,  38,  55, -74, -65,  36, -64, -54, -69, -65,  13,  12, -50, -61,  31,  26,  16, -87, -66;
/M: SY='I';  M= -62,  37, -80, -73, -51, -84, -76,  59,  21,  44, -38, -74, -77, -69, -67, -70, -58,  44, -77, -59;
/M: SY='L';  M=  -6,  37,  -1, -67, -55, -73, -70,  28, -70,  52, -44, -67,  25, -66, -73,  22,   0,  -2, -78, -62;
/M: SY='S';  M= -58,  39,   4, -62,   8, -67, -61,  -7, -60,  12,  25,  10,  41, -60,   5,  47,   6, -57, -73,  14;
/I:         I=-19; MD=-47;
/M: SY='H';  M= -68, -79,   3,   2, -56, -82,  45,   3, -60,  39,  30, -68,  15, -60,  33, -70, -65,  -1, -76,  21; D=-19;
/I:         I=-19; MD=-47;
/M: SY='L';  M= -65, -77, -71, -71, -56,  20, -67,  23,  -9,  44, -49,  18,  38, -68, -71, -65,   2, -53, -73,  22; D=-19;
/I:         I=-19; MD=-47;
/M: SY='R';  M= -65, -82,  37,  45, -80, -73, -58,   2,  38, -75, -68,  15, -69,  19,  47,  -6, -60, -71, -83, -69; D=-19;
/I:         I=-19; MD=-47;
/M: SY='R';  M= -65, -78, -71,   7, -61, -81,  25,  43, -58,  24, -49, -69,   6, -60,  45,  -1, -61,  21, -81, -62; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='C';  M= -82,  34, -88, -82, -81,  21, -80, -87,  -9,   2, -76, -81, -96,  18,  27, -80, -85, -87, -89,  16; D=-19;
/I:         I=-19; DM=-47;
/M: SY='I';  M= -85,  38,   5, -85, -78,-102, -92,  40,  -4,   7, -66, -86, -97, -85,  -5, -88, -80, -11,-100, -82; D=-19;
/I:         I=-19; DM=-47;
/M: SY='M';  M=  -9, -90,  -2,  26,   9, -87, -78, -73, -10,   8,  37, -78,  10, -71, -77, -10, -74, -75, -89, -74; D=-19;
/I:         I=-19; DM=-47;
/M: SY='N';  M= -63, -77,  52, -49,   5, -64,  37, -75,  -2, -76, -68,  57,  56, -53,  34,   0,   3, -75, -83, -62;
/M: SY='P';  M= -62,  44,   1, -58, -59,  17,  37, -70,   3, -21, -61, -59,  70,  18, -62,   1, -60, -71, -65,  63;
/M: SY='H';  M=  46, -71,  12,   3, -77,  21,  55, -76,  39, -74, -65, -51, -65, -51,   5,   0,   8, -67, -80, -65;
/M: SY='D';  M= -63,  29,  67, -53, -64, -72,  37,  27, -62,  14, -53,  17, -72,  16, -66, -58,  12,  18, -87, -61;
/M: SY='C';  M=  -2,  65, -72, -70,  51,  -8,  33,  39, -62, -53, -53, -62, -75, -66,  26,   2,   7,   1, -71, -51;
/M: SY='L';  M= -15,  30, -82, -76,  20, -82, -69,   5, -76,  67, -36, -79, -82, -72, -75, -71, -60,  29, -67,  24;
/M: SY='F';  M=  31,  34, -78, -74,  71, -73, -65, -42, -72, -48, -50, -73, -79, -73, -72, -62, -58,  51, -54,  64;
/M: SY='I';  M= -60,  34, -69,  27, -55, -12, -72,  60, -68,  25,  37, -69, -72, -64, -72, -64,  12,  23, -78, -61;
/M: SY='G';  M=  19, -74, -65, -74, -82,  97, -71, -86, -69, -83, -73, -51, -68, -66, -76, -48, -66, -78, -74, -77;
/M: SY='E';  M= -61, -80,  61,  91, -84,   4, -54, -85, -47, -80, -75,  22, -60, -41, -56, -55, -59, -79, -85, -73;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='S';  M=  38, -64, -62, -60, -67, -54, -63, -61, -61,  17, -58, -52, -67, -54, -65,  84,  12, -56, -79, -65;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='G';  M=  51, -68, -58, -65, -78,  65, -63, -77, -61, -78, -69,  51, -68, -59, -68,  25, -54, -69, -78, -73;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='M';  M= -64,  49, -80, -77, -62, -80, -70,  25, -72, -13, 101, -68, -76, -69, -75,  -1,  48, -49, -85, -64; D=-26;
/I:         I=-26; DM=-65;
/M: SY='M';  M=  15, -72, -78, -73, -62, -72, -70, -49, -72,  30,  76, -69, -77, -66, -73,  42,   3,   7, -83, -65; D=-26;
/I:         I=-26; DM=-65;
/M: SY='R';  M=  -9, -71, -67, -60, -63, -70, -61,   0,  10,  10,  35, -59, -71, -52,  65,  37,   7,   7, -77, -61;
/M: SY='C';  M=  11,  60, -74, -70, -56, -74, -73,   5, -70,  45, -45, -69,  25, -70, -74, -58,  44,  27, -80, -63;
/M: SY='Y';  M=  18, -71, -78, -74, -39, -77, -60,   6, -72,  53, -39, -76, -80, -67, -71, -66, -60,  31, -57,  77;
/M: SY='L';  M=  -5,  39,   1,  28, -59, -73, -63, -51,   0,  52, -47, -63, -73,  17,   3,   6, -58,  -9, -77, -62;
/M: SY='Q';  M= -13, -76, -49,  51, -63, -67,  38, -70,   6, -13, -59,  42, -67,  53,   6,   0, -57, -70, -69,  46;
/I:         I=-28; MD=-71;
/M: SY='M';  M= -66, -75, -71, -68, -57, -77,  68,   1,   0,  22,  78,   9, -75, -62, -64, -64,  25,  -8,  63, -53; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='W';  M= -70, -80, -79, -72,  53, -15,  25, -54,  23,  21, -53, -73, -81, -68, -64, -71, -69,  -3, 100,  51; D=-28;
/I:         I=-28; DM=-71;
/M: SY='P';  M= -60, -84, -61,   5, -82,  29, -64, -78,   2, -82, -70, -61,  98, -56,  36,   1, -59, -78, -78, -76;
/M: SY='N';  M= -60, -73,  29, -55, -71,  23,  37, -67, -53,   6, -60,  55,   7,  17,  16, -50,  46, -67, -84, -64;
/I:         I=-30; MD=-77;
/M: SY='S';  M=  15,  29,  10,   5, -77, -65, -64,  14, -55, -72, -67,  13,  25, -56,  31,  50, -54, -63, -85, -72; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='K';  M= -63, -76, -63, -54, -63, -74, -60,  19,  66, -13, -56, -57,  25, -50,  49, -58,  33, -58, -70,  23;
/M: SY='I';  M= -61,  36, -75, -76,  14,  14, -70,  55, -73,  35, -43,   4, -77, -70, -75,  -3, -58,  10, -69,  14;
/M: SY='Y';  M= -66, -75, -82, -80,  66, -84, -64,  62, -74, -40, -43, -76, -80, -74, -74, -70, -61,  36, -50,  77;
/M: SY='Y';  M= -70, -76, -75, -74,  76, -78, -50, -53, -69,  -8, -50, -72,  16, -69, -68, -66,  11, -57, -38, 103;
/M: SY='N';  M= -60, -69, -44, -57, -73, -56, -48, -71, -45, -73,  34, 104, -71, -49,  43,   9,  17, -71, -89, -67;
/M: SY='S';  M=   0, -63, -57, -58, -72, -55, -62, -67, -57, -71, -66, -46, -62, -53, -63,  86,  73, -59, -84, -66;
/M: SY='L';  M= -63, -70, -80, -76, -45,  30, -69, -38, -77,  84, -33, -76, -81, -70, -75, -71, -64, -45, -71, -57;
/M: SY='F';  M=  17, -70, -76, -68,  58, -76, -69,   3,  36,  45, -43, -70, -76, -66, -61, -65, -59,  18, -65, -47;
/M: SY='D';  M= -56, -73,  77,  29, -71, -63, -57,  -6, -55, -72, -69, -44, -64, -51, -62,  55,  33, -65, -82,  13;
/M: SY='S';  M=  -7,  29,  36,  34, -70,  -6, -61, -63, -58,   5, -61,  17,   7, -55, -65,  39,  13,  -8, -84, -68;
/M: SY='N';  M= -59,  29,  46,   6, -75,  23,  35, -76,   5, -16, -66,  52, -69, -51,  17,  25, -55, -73, -85, -66;
/M: SY='D';  M= -62, -77,  93,  17, -73, -63, -51, -75, -53, -73,  33,  20, -67,  22, -59,  25, -54, -74, -84,  18;
/M: SY='H';  M=  -2, -74, -60, -58, -64, -70,  73,  24,   0,  10, -51,  41, -72,  22,  37, -56,   3,  -9, -81, -57;
/M: SY='P';  M= -61, -78, -60,  29, -66, -70,  58,  47, -60, -56,  55,   6,  68, -56, -66,  20, -56, -52, -81, -61;
/I:         I=-20; MD=-50;
/M: SY='P';  M=  15, -86, -76, -73, -87,  30, -79, -81, -75, -23, -76, -71,  72, -73, -82,  30, -65, -79, -88, -85; D=-20;
/I:         I=-20; MD=-50;
/M: SY='Q';  M= -67, -88, -56,  49, -88, -77,  30, -81, -52, -20, -66, -60, -72,  97, -54,  -3, -68, -81, -84, -69; D=-20;
/I:         I=-20; MD=-50;
/M: SY='R';  M= -69, -86,  40, -62, -79,  14, -69,   0, -51, -72, -68, -63, -81, -61,  73, -68, -69,  22, -89, -73; D=-20;
/I:         I=-20; MD=-50;
/M: SY='E';  M= -66, -81, -62,  38, -68,  22,  36, -66, -66, -13,  34,  12, -75, -62, -71, -62,  26,  -6, -81,  27; D=-20;
/I:         I=-20; MD=-50;
/M: SY='S';  M= -68, -82,  17,   4,  12, -76,  29, -68, -66,  19, -62, -65,  20, -63,   1,  39, -63, -70, -77,  21; D=-20;
/I:         I=-20; MD=-50;
/M: SY='N';  M=  14, -83, -72, -77, -86,  36, -75, -83,  -4,  -9, -76,  39, -83, -71, -76,  24, -67, -80, -93, -83; D=-20;
/I:         I=-20; MI=-50; MD=-50; IM=-50; DM=-50;
/M: SY='P';  M= -74,  43, -82, -73,  10, -84, -79,  26, -72,   9, -60, -81,  84, -76,   5, -76, -69, -61, -82, -71; D=-20;
/I:         I=-20; DM=-50;
/M: SY='Y';  M=  -4, -70,  14,  -1,  37, -71, -62,  12, -65,   7,  32, -62, -72, -62, -68,  23,   9,  19, -64,  44;
/M: SY='P';  M= -65, -87, -66, -56, -80, -69, -70,  -1,   7, -76, -66, -69, 118, -64, -68, -61,   7, -69, -79, -78;
/M: SY='P';  M= -12, -76, -66, -61, -72,   1, -69,  -7, -64, -14, -60, -63,  94, -64, -72,  23,  32, -10, -80, -72;
/M: SY='E';  M= -56, -76, -45,  76, -77, -68, -54, -74, -43, -69,  34, -53, -62,  48,  34,  41,   4, -69, -79, -66;
/M: SY='F';  M=  28, -68, -76, -71,  72, -68, -64, -46, -69,   0,  61, -67, -75, -67, -69,  29, -55,  17, -59,  23;
/M: SY='L';  M= -13, -71, -73, -67, -53,  -8, -67,  39, -64,  58, -41, -67, -75,  20,   8,  26, -57, -43, -74, -58;
/I:         I=-7; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='M';  M= -87, -97,-105, -98, -79,-106, -97, -61, -98,  25,  29,-101,  14, -96,-100, -92,   1,  22,-106, -86; D=-7;
/I:         I=-7; DM=-17;
/M: SY='C';  M= -90,  47,  34, -80, -91, -91, -81, -99, -85,-101, -95,  38,  12, -86, -92, -79,   4, -97,-105,  20; D=-7;
/I:         I=-7; DM=-17;
/M: SY='D';  M= -91,  38,  56, -72,-104, -91, -82,  -6, -82, -97, -94,  35, -98,  15, -89, -81, -83, -92,-119, -96; D=-7;
/I:         I=-7; DM=-17;
/M: SY='M';  M= -82, -94,-101, -94, -71,-103, -89,  27,  -2, -61,  57, -93, -97, -87, -86, -90, -79,  39, -92,  19; D=-7;
/I:         I=-7; DM=-17;
/M: SY='D';  M= -77, -92,  35, -67, -93, -83, -74, -87, -68, -87,  25,  19,  12,  18,   6,  -5,  32, -85,-104, -84; D=-7;
/I:         I=-7; DM=-17;
/M: SY='E';  M= -77, -98, -69,  39,-100,  32,  39,-105,  25, -99, -90, -70, -83, -66, -70, -10, -81, -99, -99, -87; D=-7;
/I:         I=-7; DM=-17;
/M: SY='L';  M= -78, -87, -96, -94,  12, -15, -91,  24, -91,  35, -55, -89, -94, -90, -93, -83,  -1,  20, -88, -69; D=-7;
/I:         I=-7; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='G';  M= -74, -95, -90, -93,   6,  60, -93, -81,  -7, -87, -84, -78, -92, -88, -89, -76, -84,  15, -92, -84; D=-7;
/I:         I=-7; DM=-17;
/M: SY='Q';  M= -80,-101, -65,  54,-101, -12, -75, -10, -67, -91, -84,  10, -84,  60, -73, -74, -81, -89, -99, -89; D=-7;
/I:         I=-7; DM=-17;
/M: SY='D';  M= -82, -96,  61,   4, -88, -92, -76,  -5, -65, -20, -77, -69, -88, -70,  39, -79, -77,  -8,-103, -82; D=-7;
/I:         I=-7; DM=-17;
/M: SY='W';  M= -77, -87, -97, -92,  52, -94, -93, -56, -89, -20, -67, -89, -95, -92, -91,  -8,   3,  42,  68, -59; D=-7;
/I:         I=-7; DM=-17;
/M: SY='K';  M= -62, -76,   4, -56, -69, -76, -65,   1,  61, -16, -57, -59, -73, -53,  49,   1, -58,  38, -80, -65; D=-7;
/I:         I=-7; DM=-17;
/M: SY='P';  M= -60,  33, -71, -62, -71, -73, -71,   3, -60, -62, -58, -70,  95, -65,  24,  -4, -56,  45, -82, -72;
/M: SY='L';  M= -61,  60, -80, -76, -49,   2, -73,   4, -75,  67, -38, -73, -80, -72, -76, -67,   8,  24, -77, -59;
/M: SY='W';  M= -68, -75, -69, -74,  74,  -5, -62, -56, -67,  -9, -56,  58, -80, -69, -70, -64, -63,  -8, 107,  43;
/M: SY='N';  M= -62, -75, -43,  27, -79,  -6, -49, -79, -41, -80, -68,  93,   7,  27,  54, -50, -55, -78, -85, -70;
/M: SY='G';  M= -53,  34,   6,   5, -70,  51, -61, -74,  30, -71,  32, -50, -66, -54, -58,  44,   9, -69, -74,  13;
/M: SY='N';  M=  22, -74, -56, -58, -61, -62,  27,  -9, -46, -69, -61,  66,  10, -51,  59,  -1, -55, -65, -70,  50;
/I:         I=-8; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='P';  M= -10, -86, -82, -78, -79, -79, -81,  20, -79, -22,  32, -75,  53, -75, -84,  37,   6, -64, -93, -80; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M=  10, -93,  48,  43, -99, -15, -71, -94, -65, -91, -84, -64,   5,  46, -71, -66, -73, -88, -96, -85; D=-8;
/I:         I=-8; DM=-19;
/M: SY='M';  M= -17, -83, -80,   1, -72, -86, -82,  25, -78,   6,  31, -76, -83, -74, -83,  15,  29,  -4, -93, -75; D=-8;
/I:         I=-8; DM=-19;
/M: SY='T';  M= -59, -73, -68, -70, -81, -72, -76, -74, -68, -78, -74, -57, -71, -68, -75,  50,  89, -66, -97, -77; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M= -80, -96,  93, -50, -83, -78, -72, -94,  -4, -92, -91, -55, -80, -67, -72, -72, -74, -95, 103, -67; D=-8;
/I:         I=-8; DM=-19;
/M: SY='I';  M=  25, -83, -83,  -4, -68, -85, -83,  59, -78,  10, -54, -81, -83,  13, -81, -72, -69,  -1, -86, -72; D=-8;
/I:         I=-8; DM=-19;
/M: SY='T';  M= -64, -80, -66,  -3, -85,  42, -75, -82, -66, -83, -77,  10, -74, -69,   0, -54,  73, -75, -93, -81; D=-8;
/I:         I=-8; DM=-19;
/M: SY='N';  M= -65, -78, -58, -67, -84, -66, -62, -79, -63, -81,  29,  79, -79,  20, -69,  41,  27, -77, -98, -77; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M= -17, -86,  30, -66, -73, -79, -79, -69,  21,   4, -69, -70,  15, -70, -70,  -1,   3,  -8,  86, -68; D=-8;
/I:         I=-8; DM=-19;
/M: SY='K';  M=  11, -82,  31,  -5, -79, -79, -73, -10,  39, -14,  31, -64, -77, -64, -63, -64,  29, -66, -91, -75; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M=  -8,  79, -77, -75, -59, -77,  73,   7, -73, -68, -65, -68, -82, -70, -74,  -3,   0, -67,  92,  45; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M= -73, -83, -88,  -9,  51, -87, -81, -49, -78,  12, -56, -87, -86, -78, -79, -79, -72,  39, 115,  22; D=-8;
/I:         I=-8; DM=-19;
/M: SY='D';  M= -14, -80,  64,  27, -82,  18, -65, -75, -64, -21, -74,  13, -73, -60, -71,  21, -61, -11, -93, -76; D=-8;
/I:         I=-8; DM=-19;
/M: SY='Y';  M=   0, -76, -70, -70,  38, -73,  31, -58,  -4,   8,  35,  13, -80, -63, -64,   1, -62, -61, -54,  82; D=-8;
/I:         I=-8; DM=-19;
/M: SY='I';  M= -67, -76, -85, -78,  10, -89, -78,  68, -77,  42, -39, -80, -81,  17, -78, -75, -63,  30, -75, -56; D=-8;
/I:         I=-8; DM=-19;
/M: SY='H';  M= -66, -81, -64,   6, -68, -78,  73,  39,  54, -62, -57, -59, -71,  16, -51, -62,   7,  -4,  52, -57; D=-8;
/I:         I=-8; DM=-19;
/M: SY='R';  M= -62, -77, -59, -57, -68, -67, -56, -10,  24, -22, -63,  52, -74,  22,  53,  39, -56, -68, -76,  21; D=-8;
/I:         I=-8; DM=-19;
/M: SY='R';  M=  -6, -79, -62,  -4, -67, -10,  26,   0, -49, -66, -60,  39, -76,  16,  60, -60, -62,  19, -77,  23; D=-8;
/I:         I=-8; DM=-19;
/M: SY='C';  M= -63,  65, -75, -73, -56, -78, -72,  31, -71,  24, -50,   8, -80,  13, -74,   1,   4,  22,  53,  13; D=-8;
/I:         I=-8; DM=-19;
/M: SY='P';  M=  11, -79, -66, -58, -79,  17, -68, -73,  44, -15, -66, -61,  70,  11, -57,  -2,  -1, -71, -79, -74; D=-8;
/I:         I=-8; DM=-19;
/M: SY='P';  M= -90,-107, -91, -88, -91, -13, -85, -93, -88, -93,  32,   1,  46,  11, -93, -84,  -1, -95, -97,  20; D=-8;
/I:         I=-8; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='M';  M= -64,  38,  31,  25, -75, -71, -57, -71, -47, -66,  71,  24, -73, -51,  60,  20, -59, -70, -86, -68; D=-8;
/I:         I=-8; DM=-19;
/M: SY='S';  M=  -3, -72,  12,  37, -77,  -1, -59, -72, -55, -72,  27, -51,  33,  21, -61,  65,   8, -67, -81, -68;
/M: SY='I';  M= -57,  37, -71, -72,   9, -74, -72,  56, -69,  11, -46,  15, -74, -68, -73,  31,  13,  38, -78, -58;
/M: SY='D';  M= -57, -73,  62,   5, -72,  31, -59,   2, -59, -14, -63,  50, -69, -56, -66,  26, -53,   5, -86, -68;
/M: SY='L';  M= -67, -71, -85, -78,  14, -87, -71,  44, -78,  80, -31, -82, -82, -73, -76, -76, -62, -35, -69, -51;
/M: SY='I';  M= -62,  44, -82, -79,   6, -85, -79,  73, -76,  33, -38, -75, -77, -75, -78, -69,   7,  36, -75, -56;
/M: SY='H';  M= -61, -73, -68, -67, -57, -78,  97,  57, -67,  -7, -45, -58, -71, -63, -67, -59,  46,  31, -86, -51;
/M: SY='C';  M= -55, 108,  17, -65, -65, -67, -65, -57, -67, -14,  75, -58, -75, -63, -70,  53, -52,  -4, -87, -66;
/M: SY='D';  M= -67, -81, 116,  19, -88, -65, -53, -86, -54, -84, -83, -36, -66, -52, -62, -56, -58, -82,-101, -71;
/M: SY='M';  M=  56, -69, -78, -71, -56, -68, -70,  66, -69,  -5,  83, -70, -71, -64, -72, -59, -57, -35, -74, -59;
/M: SY='E';  M= -60, -81, -31, 112, -84, -76, -53, -85, -41, -77, -73, -57, -55, -34, -51, -57, -61, -77, -80, -74;
/M: SY='I';  M= -56, -69, -66, -70,  13,  17, -70,  52, -66, -15, -51,  24, -70, -66, -71,  24,  47,  19, -77, -59;
/M: SY='T';  M= -56, -72, -59, -58, -71,  14, -62,  -5,   4, -16, -60,  21,  39,  16,  17,  23,  59, -60, -80, -67;
/M: SY='D';  M=  -7, -78,  66,   6, -81,  50, -62,  -6,   3, -77, -71,  12,  42, -57, -63, -54, -59, -71, -83, -73;
/I:         I=-19; MD=-47;
/M: SY='D';  M= -62, -78,  64,  10, -76,  -3,  26,  -6, -57, -23, -67,  40, -72, -56,   7,  23, -57, -13, -91, -68; D=-19;
/I:         I=-19; MD=-47;
/M: SY='K';  M=  19, -78,   8, -64, -72, -76, -73, -63,  47,  26, -61, -66, -78, -64, -60,   1,  -3,  -8, -86, -72; D=-19;
/I:         I=-19; MD=-47;
/M: SY='N';  M= -76, -86,  48,  12, -89, -72,  26,  -9, -63, -87, -80,  84, -82, -62, -71, -63, -65, -83,-106, -79; D=-19;
/I:         I=-19; MD=-47;
/M: SY='W';  M= -77, -95,  -3, -73,   9,  -3, -82, -81, -72, -83, -80, -75, -88,  45,   4,  -6,   1, -12,  81, -68; D=-19;
/I:         I=-19; MI=-47; MD=-47; IM=-47; DM=-47;
/M: SY='E';  M= -70, -88, -66,  45,  10, -82, -69,  -5, -67, -23, -71, -70, -80,  41, -71,  37, -67, -73, -80,  17; D=-19;
/I:         I=-19; DM=-47;
/M: SY='E';  M= -68,  36, -63,  40, -82, -81, -70, -75,  38, -15, -70, -65, -76,  20,   0,   5,   6, -14, -89, -76; D=-19;
/I:         I=-19; DM=-47;
/M: SY='I';  M= -73, -84, -87, -79, -63, -93, -79,  46,  -2,  26,  34, -81, -86, -71,  35, -79, -70,  16, -85, -67; D=-19;
/I:         I=-19; DM=-47;
/M: SY='L';  M= -66, -80,   9,  26, -62, -80, -68,  -2, -67,  31, -55, -69, -78,  25, -71,  21, -62,  17, -79,  21; D=-19;
/I:         I=-19; DM=-47;
/M: SY='H';  M= -57, -73,  20,  26, -73, -69,  53,  -5,   3, -66, -60, -50, -65,  48,   9,  21,  51,  -6, -83, -61;
/M: SY='E';  M=  -7, -73,   6,  49, -59, -74, -61, -49, -57,  46,  39,   9,  14, -54,  -1, -62, -59,   7, -78, -63;
/M: SY='W';  M=  -6, -77, -78, -70,  16, -77,  56,  42, -69,  17, -46, -71, -77,  14, -69, -67, -64,  21, 102,  26;
/M: SY='Y';  M=  19, -77, -67, -60, -48, -71, -54,  39,   5, -57, -53, -62, -73,  30,  48,  -1, -59, -52, -56,  80;
/M: SY='Q';  M=  -7, -72,  14,   0, -77, -62,  33, -73,  24, -73, -64,  57, -65,  64, -50,  -2,  49, -69, -84, -64;
/M: SY='H';  M=  -8, -72, -69, -69, -51, -73,  73,  43, -68,  36, -43,   9, -75, -62, -68,   9, -57,  23, -75,  19;
/M: SY='I';  M= -57, -69, -77, -75, -53, -80, -76,  63, -72,  12,  27, -69, -73, -70, -75,   2,  33,  57, -80, -59;
/M: SY='M';  M= -56, -70, -64, -62, -61, -66, -60,   1,  -1,  27,  61,  16,  11, -55,  24,  54,   1, -53, -78, -61;
/M: SY='T';  M=   0,  29,   9, -64, -63, -67, -67,  50, -63, -53,  31,  11, -68, -62, -69,  38,  52,  -1, -83, -64;
/I:         I=-20; MD=-50;
/M: SY='C';  M=  49,  92,   3, -68, -67, -68,  59, -67, -71,  13, -60, -66, -79, -68, -73, -60, -64, -63,  63, -63; D=-20;
/I:         I=-20; MD=-50;
/M: SY='L';  M= -67, -75, -77, -71,   9, -83, -67,  25,  17,  47,  36, -70, -78, -65,   7, -67,  31, -47, -71,  15; D=-20;
/I:         I=-20; MD=-50;
/M: SY='H';  M= -13, -81,   8, -64, -60, -78,  59,  23, -62,   5, -56,  11, -79,  29,   7, -64,   4, -60, -75,  46; D=-20;
/I:         I=-20; MD=-50;
/M: SY='C';  M= -62,  77, -79, -76, -62, -78, -73, -52, -74,   8,  35, -71,  14, -73, -77,  30,   7,  32, -83,  17; D=-20;
/I:         I=-20; MD=-50;
/M: SY='S';  M= -67, -81, -83, -82, -70,  13, -79, -59, -81,  35,  29, -74, -85, -76, -83,  36,   6,  -3, -90, -74; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='H';  M= -63,  37,  29,  39, -75,  -5,  71, -11,   2, -68,  29,  17,  17,  21,  10, -57, -61, -70, -84, -62;
/M: SY='C';  M= -60,  49,  34,  42, -66, -10,  26,  23, -56, -65, -62, -54,  14, -54,  -1,  -1,  33, -59, -78,  22;
/M: SY='W';  M= -59, -79,  67, -51, -73,  34,  33, -76, -59, -16, -69, -50,  40, -57,  -2,  32, -58, -76,  68, -63;
/M: SY='G';  M= -55, -72, -64, -61, -66,  54, -66, -60,  53,  27, -56, -55, -69, -57, -54,  21,   9, -11, -75, -66;
/M: SY='C';  M= -61,  62,   9, -68, -48, -78, -64,  27,  -8,  -9,  39, -66, -76, -67, -67, -63,  16,  46, -67,  61;
/M: SY='L';  M= -58, -67, -78, -73, -48, -78, -71, -32, -73,  69, -36, -74, -79, -68, -73,  30, -54,  51, -77, -57;
/M: SY='I';  M= -61, -73, -85, -81,  15, -88, -83,  83, -78,  -1, -38, -77, -77, -77, -80, -71, -56,  59, -74, -54;
/M: SY='M';  M=  -6, -72, -75, -72,  10, -75,  45,  60, -70,  14,  65, -67, -74, -64, -70,  19, -57,  -3, -69,  20;
/M: SY='K';  M= -62, -75, -55, -42, -78, -70, -59, -77, 106, -77, -65, -48, -62, -41, -26, -55,  16, -72, -73, -65;
/M: SY='Y';  M= -60, -71,  13, -68, -45, -78, -62,  43, -67,  -9, -47, -63, -73, -67, -70, -57,  56,  39, -63,  73;
/M: SY='H';  M=  11, -75, -67, -64,  40, -71,  88, -60, -59,  -9,  31, -60, -75, -57,  16,   0, -61, -62, -56,  76;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='W';  M= -67, -81, -67,  12, -55, -78, -63,   6,   2,  24, -53, -68,  36,  37, -63, -63,  26, -58,  61,  48; D=-18;
/I:         I=-18; DM=-45;
/M: SY='Y';  M=  -6, -75,  25,   3,  11, -72, -59, -59, -62,  10, -57, -61, -75, -60,  -2,  30,   4,  -7, -64,  65; D=-18;
/I:         I=-18; DM=-45;
/M: SY='N';  M= -66, -78,  49, -56, -71, -68, -59,  18, -61,   4,  34,  61,  39,  20, -67,  -1, -57, -61, -87, -68; D=-18;
/I:         I=-18; DM=-45;
/M: SY='G';  M=  -9, -75, -75, -74,  11,  43, -69,   2, -72,   5,  39, -66,  10, -69, -75,   1,  -2,   6, -70,  23; D=-18;
/I:         I=-18; DM=-45;
/M: SY='D';  M= -66, -78,  45,  29,   8, -76, -62,  20,  30, -65, -63, -55, -69, -55,  13, -58,  42, -60, -74,  23; D=-18;
/I:         I=-18; DM=-45;
/M: SY='Y';  M= -67, -83,  26,  29,  32,  20,  45, -76,   3, -71, -66, -57,  12,  16,   6, -62, -66, -76, -66,  48; D=-18;
/I:         I=-18; DM=-45;
/M: SY='F';  M= -65, -72, -70,  -2,  58, -78, -66,  26,  19,  26,  40,   9, -74, -64, -63, -65,   7,  -1,  53, -45;
/M: SY='T';  M=  16, -71,   6,   9, -67, -65,  36, -61, -59,  22, -55, -55,  38,  18, -63,  25,  47, -59, -81, -63;
/M: SY='N';  M= -64, -75,  12, -58,  13,  -6,  27,  -5, -52, -12, -58,  65, -73,  30,  27, -55,   5, -65,  62,  24;
/M: SY='L';  M= -64, -74, -70, -64,  37, -14, -62,  24, -56,  46, -44,   5, -77,  39,  40,  -4, -60, -49, -68, -51;
/M: SY='M';  M= -64,  40, -77, -75,  11, -80,  29,  39, -72,  47,  63,  12, -79, -68, -72, -69, -59,  21, -75, -52;
/M: SY='N';  M= -56, -70,  34, -54, -73,  -1, -55, -72, -48, -20, -65,  60, -69, -51,  46,  50,  30, -68, -85, -67;
/M: SY='M';  M= -60, -71, -71, -71,  14, -72, -60,  45, -68,  33,  57,  14, -75, -63, -69,  40, -54, -43, -63,  48;
/M: SY='Y';  M=  -7, -72, -79, -74,  17, -80, -63,  27, -69,  54, -39, -76, -80, -68,   1, -69, -61,  19, -59,  63;
/M: SY='W';  M=  43, -73, -69, -63, -60,  32, -64,   1,  18,   9, -56, -62, -72, -57,  36, -56, -61, -58,  61,  24;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='P';  M= -69,  36, -72, -64, -89, -76,  29, -88,   4, -88, -77, -66,  61,  20,  34,  37, -65, -85, -92, -78; D=-16;
/I:         I=-16; DM=-40;
/M: SY='Y';  M= -73,  39, -85, -87, -49,  24, -66, -61, -82,  22, -59, -80, -91, -78, -82, -75, -74,   0, -62,  83; D=-16;
/I:         I=-16; DM=-40;
/M: SY='F';  M=  -8, -82, -86, -81,  87, -82, -68, -65, -72, -59, -63, -78, -88, -77,  14,  -1, -71, -67,  54,  50; D=-16;
/I:         I=-16; DM=-40;
/M: SY='G';  M= -66, -85,   0,   1, -75,  46,  30, -85,   6, -82, -74, -59,  10, -63,   4, -60,  29, -81, -79,  31; D=-16;
/I:         I=-16; DM=-40;
/M: SY='S';  M=  -7, -81, -59,  44, -82, -71, -65, -80,   5, -20, -71, -61, -73,  22,  33,  50, -59, -75, -86, -74; D=-16;
/I:         I=-16; DM=-40;
/M: SY='V';  M=   2, -77, -86, -84, -65,  19, -87,  29, -81,  -5, -53, -79, -83, -81, -84, -70, -63,  66, -88, -71; D=-16;
/I:         I=-16; DM=-40;
/M: SY='Q';  M= -70, -82, -59,   8, -67, -74, -57, -74, -55, -19, -66,  57, -78,  60,   9, -59,  28, -74, -75,  49; D=-16;
/I:         I=-16; DM=-40;
/M: SY='L';  M= -71, -78, -91, -85, -53, -14, -80,   7, -85,  69, -41, -87, -89, -80, -84, -81, -69,  21, -82, -64; D=-16;
/I:         I=-16; DM=-40;
/M: SY='I';  M= -72,  34, -88, -81,  41, -91, -81,  51,   0,  13, -51, -80, -86, -77,   6, -78, -68,  20, -76, -57; D=-16;
/I:         I=-16; DM=-40;
/M: SY='W';  M= -58,  29, -64, -60,   9,  -3, -63, -60,  27, -64, -60,  11, -70,  16,   7,   4,  47,  14,  73,  21;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='C';  M= -58,  80, -60, -62, -71, -64, -63, -65, -61, -21,  33,  46,  69, -62, -69,  27,  43, -63, -86, -71;
/M: SY='R';  M= -62, -75,   6, -55, -63,  -4, -55,   1,  -2,   2, -55,  42, -72,  45,  52, -56,   5,  -6, -73,  23;
/M: SY='Y';  M=  -9, -72, -67, -69, -43,  30, -54, -57, -66,  23, -52, -61, -73, -61, -67,  29,  28, -58, -53,  88;
/M: SY='S';  M=  21, -65, -55, -57, -74, -52, -58, -72, -53, -75, -68,  26, -65, -50,  12,  91,   8, -64, -82, -67;
/M: SY='N';  M= -57,  40,  11, -50, -77, -58, -52, -77,  38, -78, -68,  76, -69,  27,  19,  50, -49, -74, -85, -68;
/M: SY='R';  M=  17, -73, -70, -62,  10, -69, -62, -56, -53,  33,  29, -65,  54, -57,  54,  21, -57, -57, -73, -59;
/M: SY='D';  M=  13, -73,  39, -53,   5,  -3, -61,  -2,  39, -66, -62,  12, -69, -53,  34,  23, -54,   1, -77, -62;
/M: SY='W';  M= -53, -71,  11, -57, -64,  13, -56, -68, -57, -68,  38,  41, -68,  30, -61,  58,  28, -67,  63,  24;
/M: SY='S';  M= -51, -69, -61, -62, -62,  -1,  34,   0, -61, -63,  34, -51,  21, -56, -65,  71,  44, -58, -74,  32;
/M: SY='E';  M= -60, -81, -32, 109, -83, -76, -53, -85, -40, -76, -72, -57, -56, -34,  10, -57, -61, -77, -80, -73;
/M: SY='W';  M=   3,  40, -80, -73, -54, -73, -77,   4, -71,   9,  26, -72, -76, -69, -73,  20, -55,  63,  91, -55;
/M: SY='Y';  M= -71, -80, -75, -75,  23, -79, -45, -52, -68,  18, -47, -75, -83, -64, -66, -69, -67, -58,  71, 120;
/M: SY='L';  M= -65,  39, -85, -78, -44, -85, -74,  16, -77,  74, -34, -82, -83, -73, -76, -75, -62,  23,  68, -53;
/M: SY='C';  M= -59,  67, -78, -73, -55, -79, -75,  31, -69,  32, -44, -72,  15, -70,   0,   1, -55,  57, -81, -62;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 73 in 73 different sequences
Number of true positive hits 73 in 73 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Mononegavirus-type SAM-dependent 2'-O-MTase
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
73 sequences

L_ABLVB (Q9QSP0), L_ABLVH (Q8JTG9), L_AMPV1 (Q2Y2L8), 
L_BEFVB (Q9E784), L_BRSVA (O91940), L_CDVO  (P24658), 
L_CHAV  (P13179), L_DMSVA (C6S3N3), L_EBLV1 (A4UHQ2), 
L_EBLV2 (A4UHQ7), L_EBORE (Q91DD4), L_EBORR (Q8JPX5), 
L_EBOSM (Q66802), L_EBOSU (Q5XX01), L_EBOZ5 (Q6V1Q2), 
L_EBOZM (Q05318), L_HENDH (O89344), L_HIRRV (Q77SJ8), 
L_HMPVC (Q6WB93), L_HRSV  (Q9IWW8), L_HRSVA (P28887), 
L_HRSVB (O36635), L_IHNVO (Q82707), L_IHNVW (Q82685), 
L_ISFV  (Q5K2K3), L_LBVAV (Q8B0U2), L_LNYV3 (Q4W382), 
L_MABVA (Q1PD54), L_MABVM (P31352), L_MABVO (Q6UY63), 
L_MABVP (P35262), L_MABVR (Q1PDC4), L_MEASA (P35975), 
L_MEASC (Q9WMB3), L_MEASE (P12576), L_MOKV  (P0C568), 
L_MPV15 (Q50EW2), L_MUMPM (P30929), L_NDVB  (P11205), 
L_NDVB1 (Q9DLD3), L_NIPAV (Q997F0), L_PI2HT (P26676), 
L_PI3H4 (P12577), L_PIV5  (Q88434), L_PIV5W (Q03396), 
L_RABVA (Q4F8Z9), L_RABVB (Q66T60), L_RABVD (Q0GBX5), 
L_RABVE (A3F5L9), L_RABVH (Q8B6J5), L_RABVI (A3RM23), 
L_RABVN (Q9IPJ5), L_RABVP (P11213), L_RABVR (Q0GBY0), 
L_RABVS (P16289), L_RINDR (P41357), L_SENDA (Q9DUD8), 
L_SENDE (P06829), L_SENDF (Q06996), L_SENDO (O55528), 
L_SENDZ (P06447), L_SHRV  (Q9QJT4), L_SV41  (P35341), 
L_SVCV  (Q91DR9), L_TIBVC (D8V078), L_TUPVT (Q4VKV2), 
L_VSIVA (P03523), L_VSIVC (Q8B0H0), L_VSIVM (Q98776), 
L_VSIVN (Q8B0I0), L_VSIVS (Q8B0H5), L_VSNJH (P13615), 
L_VSNJO (P16379)
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PDB
[Detailed view]
13 PDB

4UCJ; 5A22; 6PZK; 6U1X; 6U5O; 6UEB; 6V85; 6V86; 6YU8; 8FPJ; 8FU3; 8SNX; 8SNY
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