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PROSITE entry PS51685


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General information about the entry

Entry name [info] SAM_MT_ERG6_SMT
Accession [info] PS51685
Entry type [info] MATRIX
Date [info] 01-AUG-2013 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU01022

Name and characterization of the entry

Description [info] SAM-dependent methyltransferase Erg6/SMT-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=288;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=283;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.8995056; R2=0.0056920; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=79073.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=3005; H_SCORE=79073; N_SCORE=21.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=457; H_SCORE=79073; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-67; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='Y';  M=-102,-109,-104,-106,  69,-109, -72, -84, -98, -80, -80,-103,-114, -96, -95, -98, -96, -90, -60, 129;
/M: SY='Y';  M=-101,-112,-100,-104, -49,-108, -67, -86, -95, -83, -80,-102,-113, -91, -92, -96, -95, -92, -57, 141;
/M: SY='N';  M= -90,-101,  84, -75,-110, -85, -79,-109, -82,-113,-105,  97, -99, -81, -90,  41, -78,-108,-126,-100;
/M: SY='L';  M= -93, -99,-114,-108, -74,-116,-104,  32,-107,  78, -62,-111,-112,-103,-106,-104, -89,  49,-105, -85;
/M: SY='V';  M=  59, -95,-107,-100, -90, -98,-103, -63, -99, -74,  78,-101,-103, -97,-101, -86, -82,  79,-111, -92;
/M: SY='T';  M= -80, -92, -87, -90, -98, -94, -96, -91, -87, -95, -91, -76, -90, -89, -95,  42, 114, -83,-117, -96;
/M: SY='D';  M= -91,-105, 104,  33,-112, -95, -86,-109, -83,-108,-106, -70, -94, -82, -92,  12,  47,-103,-125,-100;
/M: SY='F';  M= -94,-100,-111,-108,  86,-113,-104,  56,-105,  -3, -74,-102,-107,-108,-106, -96,  36,  37, -91, -69;
/M: SY='Y';  M=-100,-111,-103,-105, -53,-110, -72,  40, -97, -79, -77,-103,-112, -93, -95, -97, -94, -81, -62, 133;
/M: SY='E';  M= -91,-112,  51, 103,-115,-103, -82,-114, -73,-107,-102, -81, -88,  52, -81, -85, -90,-108,-112,-101;
/M: SY='Y';  M= -95,-110, -93,  43,  28,-102, -81, -94, -91, -90, -89, -97,-104, -86, -93,  29, -92, -97, 103, 107;
/M: SY='G';  M= -82,-108, -95,-106, -93, 100, -93,-113, -99,-108,-100, -83,-100, -96,-104, -82, -98,-109, -91,  65;
/M: SY='W';  M=-106,-124,-130,-111,  54,-105,-125, -98,-103, -94, -99,-122,-110,-105,-106,-111,-114,-110, 175, -55;
/M: SY='G';  M= -78,-104, -93,-102,-111, 101, -99,-118, -97,-115,-105, -79, -97, -94,-104,  37, -91,-111,-105,-106;
/M: SY='Q';  M= -84,-105, -81,  14,-112,  34, -83,-107, -78,-105, -95,  45, -96, 100, -82,  30,  14,-104,-108, -97;
/M: SY='S';  M= -79,  54, -82, -88,-103, -84,  68,-106, -87,-106, -98,  57, -98, -81, -90,  94, -72,-100,-118, -93;
/M: SY='F';  M=-106,-101,-118,-114, 128,-113, -98, -79,-109, -70, -81,-107,-116,-120,-106,-104, -97, -84, -70, -49;
/M: SY='H';  M= -99,-111, -83, -83, -98,-101, 155,-116, -88, -98, -84, -73,-100, -77, -82, -89, -98,-116,-133, -67;
/M: SY='F';  M=-106,-101,-118,-114, 128,-113, -98, -79,-109, -70, -81,-107,-116,-120,-106,-104, -97, -84, -70, -49;
/M: SY='C';  M=  54,  80, -97, -94,-100, -87, -99, -86, -94, -94, -91, -87,-101, -90, -98,  72, -76,  35,-114, -99;
/M: SY='P';  M= -94,-114, -94, -82,-110,-101, -90,-105, -72,-107, -96, -91,  99,  32,  80, -88,  21,-104,-108,-101;
/M: SY='F';  M= -98,-108,-100, -95,  83,-104,  49, -93, -86, -87, -87, -95,  57, -92,  47,   6, -92, -95, -83,  62;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='W';  M=  -2,-103,-101, -99,  54,-101,  52,   6, -96, -83, -83, -93,-104, -95, -97,  14,  36,   7,  76,  74;
/M: SY='K';  M= -94,-111,  39,  44,-112,-100, -89,-109,  82,-110,-100, -82,  72, -75, -71, -88, -88,-107,-108,-101;
/M: SY='G';  M= -82,-105,  16, -98,-100,  93, -95,-111, -96,-108,-101, -80, -98, -95,-103, -79,  36,-106,-100,  38;
/M: SY='E';  M= -90,-111, -67, 101,-114,-103, -83,-112,  39,-106, -99, -84, -88,  64, -74, -85, -90,-107,-107,-100;
/M: SY='S';  M=  25, -98, -88, -84,-107, -84, -91,-103,  42,-107, -98, -80,  46, -80, -84,  90, -73, -96,-109, -99;
/M: SY='F';  M=-101,-102,  19,-101,  95,-111,  43, -75,-104,  57, -72,-100,-112,-104,-102,-102, -95, -81, -87, -64;
/M: SY='E';  M=  23,-106, -77,  78, -99, -98, -84,-106,  39,-103, -96, -86, -93, -71,  42,   8, -87,-100,-100,  37;
/M: SY='Q';  M=  26,-105,  47,  60,-112, -95, -85,-105, -77,-102, -95, -80, -92,  88, -82, -78,  36, -99,-110, -97;
/M: SY='A';  M=  89, -92, -94, -89,-105, -79, -96, -98, -91,-100, -94, -86, -95, -85, -95,  66, -76, -86,-108,-100;
/M: SY='I';  M= -90,-101,-107,-106, -81,-113,-108,  83,-102,  25, -69, -99,-102,-102,-106, -91,  58,  27,-108, -88;
/M: SY='K';  M=  72,-100, -92, -80,-107, -90, -92,-103,  75,-102, -93, -85, -96, -77,  45, -79, -86, -93,-104, -98;
/M: SY='R';  M= -91,-108, -95, -86, -99,-102, -86,  10, -63, -11, -88, -87,-104, -75, 105,  41, -88, -92,-106, -92;
/M: SY='H';  M= -99,-107, -90, -89, -87,-105, 139, -92, -93,  47, -74, -81,-104, -83, -88, -94, -96, -96,-121, -71;
/M: SY='E';  M= -91,-111, -64, 110,-110,-105,  79,-115, -74,-105, -99, -84, -87, -66, -81, -87, -92,-108,-113, -95;
/M: SY='H';  M= -96,  82, -84,  39, -99,-103, 131,-107, -88, -94,  50, -80,-100, -80, -87, -90, -95,-105,-125, -78;
/M: SY='Y';  M= -95,-105, -98, -98,  48,-102,  79, -87, -95, -80,  74, -91,-106, -89, -92,  29, -90, -90, -78, 101;
/M: SY='L';  M=  27, -99,-112,-105, -79,-108,-103,  56,-104,  57,  52,-106,-106, -99,-104, -97, -88,  26,-105, -87;
/M: SY='A';  M=  98, -92,-100, -92,-101, -83,-102, -84, -94, -91, -87, -94, -98, -91, -98, -74, -82,  32,-107,-100;
/M: SY='H';  M=   4,-107,  72,  44, -88,-100,  75, -96, -87,  20, -87, -82, -99, -82, -91, -89, -91, -96,-102,  57;
/M: SY='Q';  M= -90,-106, -89, -76,-101, -98,  45, -97,  65,  19, -85, -82, -98,  80,  18,  30, -87, -97,-105, -89;
/M: SY='M';  M=  49, -99,-110,-103, -81,-102,-100,  55,-102,  53,  72,-103,-104, -96,-103, -93, -88, -66,-103, -88;
/M: SY='G';  M= -85,-108, -83,  43,-112,  76, -90,-115,  14,-111,-101,  19, -96,  28,  36, -82, -93,-110,-106,-102;
/M: SY='I';  M= -93,-103,-115,-111, -77,-118,-109,  87,-108,  51, -64,-109,-108,-104,-109,-104, -89,  34,-105, -86;
/M: SY='K';  M= -87,-102, -86, -79,  25, -95, -87,-101,  68,-100, -93,  19, -96,  56,  16,  41,  36, -98,-103, -88;
/M: SY='P';  M= -93,-114, -80,  69,-113,-101, -90,-109,  52,-110,-100, -90,  94, -76,   7, -90, -89,-107,-108,-104;
/M: SY='G';  M= -86,-105,  60, -87,-112,  82, -89,-116, -90,-115,-106,  71, -99, -89, -98, -79, -90,-112,-114,-105;
/M: SY='M';  M= -84,-102,   8,  11, -97, -97, -87, -80, -85, -82,  93, -86, -98,  77, -87,  49, -82,  35,-109, -90;
/M: SY='K';  M= -94,-105, -90, -80, -96,-103,  79, -95,  85,  28, -83, -82, -98, -77,  19, -89,  14, -95,-107, -86;
/M: SY='V';  M= -85,  82,-113,-109, -86,-114,-115,  39,-106, -72, -75,-106,-110,-108,-108, -97, -83,  93,-117, -94;
/M: SY='L';  M= -97,-100,-115,-107, -71,-117,-100,  17,-108,  94, -59,-113,-113,-101,-106,-107, -93, -67,-101, -83;
/M: SY='D';  M= -98,-111, 125, -61,-118, -94, -83,-116, -85,-115,-114, -65, -97, -84, -93, -86, -87,-113,-133,-100;
/M: SY='V';  M=   3, -98,-112,-107, -84,-111,-114,  59,-105, -69, -72,-106,-106,-105,-107, -95, -83,  92,-113, -91;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='C';  M= -91, 158,-111,-111,-101,-107,-111,-108,-107, -99, -99, -97,-122,-115,-113, -94, -91, -96,-131,-112;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='V';  M= -85, -99,-114,-109, -83,-116,-116,  58,-106, -67, -70,-108,-108,-107,-108, -98, -82,  97,-114, -90;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='P';  M= -93,-116, -99, -88,-109,-101,-102, -88, -95,-103, -94,-104, 124, -98,-106, -94, -87,  35,-111,-109;
/M: SY='M';  M=  55, -96,-103, -97, -90,  -4, -92, -78, -95,  -3, 116, -93, -98, -90, -97, -83,  36, -78,-106, -89;
/M: SY='R';  M= -97,  47,-100, -89, -92,-110, -88, -90, -67,  47, -80, -94,-109, -80, 102, -96, -95, -91,-106, -91;
/M: SY='E';  M=  27,-106,  51,  89,-112, -97, -86,-108, -77,-104,-100, -81, -90,  30, -85, -81,  21,-100,-113,-101;
/M: SY='I';  M= -95,-108,-116,-115, -79,-121,-116, 115,-109, -62, -65,-106,-104,-106,-113,-104, -88, -49,-103, -86;
/M: SY='A';  M=  86,  71, -96, -92,-104, -84,-100, -96, -93, -97, -92, -89, -97, -91, -98,  10,  41, -84,-110,-101;
/M: SY='R';  M=   2,-107,  50,  14,-108, -98, -86,-100,  16,-102, -95, -81, -98,  52,  71,   7, -87,   1,-110, -95;
/M: SY='F';  M=-104,-104,-108,-106, 114,-110,  75, -84,-103, -75, -81, -99,-113,-106, -99,-100, -97, -89, -74,  56;
/I:         I=-30; MD=-77;
/M: SY='T';  M= -85,-100, -95, -97,-108, -98,-102,-102, -95,-106,-102, -84, -99, -94,-102,  68,  92, -94,-124,-104; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='G';  M= -85,-107,  46, -89,-112,  87, -92,-117,  13,-114,-104,  27, -98, -88,  12, -81, -93,-112,-109,-104;
/M: SY='C';  M=  82, 111,-101, -96,-104, -87,-102,-100, -96, -98, -94, -92,-103, -95,-101,  12, -83, -87,-113,-104;
/M: SY='N';  M= -92,-103, -76,   7,-105, -92,  51, -99,  65,-104, -93,  90, -98,  34, -73, -82, -84,   4,-114, -94;
/M: SY='I';  M= -90,-101,-114,-109, -78,-117,-111,  72,-107,  41, -66,-109,-108,-105,-108,-101, -86,  70,-108, -88;
/M: SY='T';  M= -84, -96, -98, -96, -91,-106,-102,   3, -87, -81, -81, -89, -99, -94,  36, -80,  85,  69,-115, -93;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='L';  M= -94,-100,-115,-108, -74,-116,-103,  38,-108,  81, -61,-112,-112,-102,-106,-105, -90,  37,-104, -85;
/M: SY='N';  M= -89, -95, -71, -88,-103, -85, -79,-100, -81,-106, -96, 114, -98, -83, -89, -71,  75, -97,-123,-100;
/M: SY='N';  M= -94,-102, -82, -97, -92, -94, -87,  81, -89, -82, -81, 105,-103, -90, -96, -85, -82, -71,-114, -94;
/M: SY='N';  M=  31, -96, -69, -87,-107, -80, -76,-104, -80,-110, -98, 123,-102, -81, -88, -73, -77,-103,-122,-102;
/M: SY='D';  M= -94,-112,  83,  71,-115, -99, -86,-112,  31,-111,-105, -78,  57, -76, -83, -87, -89,-109,-116,-103;
/M: SY='Y';  M= -98,-108, -90, -95, -60,-101, -70, -92,  30, -90, -84,  56,-108, -85, -84, -90, -91, -96, -68, 125;
/M: SY='Q';  M= -89,-114, -79,  45,-119, -99, -78,-107, -70,-102, -90, -81, -94, 130, -72, -80, -92,-107,-103, -93;
/M: SY='I';  M=  31,-101,-112,-107, -84,-109,-113,  89,-105, -68, -71,-104,-104,-103,-108, -94, -85,  58,-108, -90;
/M: SY='Q';  M=  -8,-105,  24,  57,-112,  22, -85,-108, -79,-105, -97,  22, -93,  79, -84,  11,  17,-103,-110, -99;
/M: SY='R';  M= -96,-111, -98, -88, -96,-110, -90,  63,   4, -87, -83, -91,-104, -78, 103, -94, -93, -80,-105, -91;
/M: SY='A';  M=  82,  50, -97, -96,-108,  63,-101,-103, -96,-103, -96, -88, -99, -93,-101, -75, -88, -92,-106,-104;
/M: SY='N';  M= -90,-100, -78, -80,-105, -93, -84,-103,  76,-106, -95,  83, -96, -77,  15, -77,  57, -99,-112, -97;
/M: SY='H';  M= -95,-108, -80,  60, -87,-103,  75, -96, -79,  19, -84,  25, -99,  52,  22, -89, -92, -98, -98,  56;
/M: SY='Y';  M= -98,-109, -95, -90, -71,-106,  75, -90,  42,  24, -79, -91,-106, -82,  37, -94, -94, -93, -82,  98;
/M: SY='N';  M=  69, -95, -85, -92,  53, -84, -88, -95, -89, -96, -92,  84,-101, -88, -94,   9, -81, -90,-102, -86;
/M: SY='K';  M=  31,-103, -86,  42,-104, -99, -92, -90,  79, -97, -91, -86, -95, -76,  19, -85, -86,  34,-107, -97;
/M: SY='K';  M= -91,-104,  39, -76,-104, -94, -85,-103,  81,  -7, -94,  57, -98, -76,  22,  15, -84,-101,-110, -96;
/M: SY='M';  M=  57,-100,  22, -89, -85, -95, -87, -85,   9,  13,  78, -92,-101, -86,  16, -86, -88, -84, -96,  53;
/M: SY='G';  M= -82,-106, -88,-101,-111,  98,  40,-118, -95,-114,-103,  49, -99, -93,-101, -79, -94,-113,-108,-103;
/M: SY='L';  M= -93,-100,-114,-108, -74,-116,-104,  42,-107,  77, -62,-111,-111,-103,-106,-104, -89,  45,-105, -85;
/M: SY='S';  M= -79,-100,  84, -75,-109, -84, -87,-108, -86,-110,-105, -70, -95, -81, -92,  94, -73,-102,-119, -98;
/M: SY='D';  M=  -3,-107,  90, -72,-110,   7,  75,-112,  39,-109,-101, -72, -96, -81, -83,  12, -87,-107,-120, -93;
/M: SY='R';  M= -93,-106, -93, -81, -95,-105, -87, -91,  53,  38, -81, -87,-101,  57,  72, -88,  17, -92,-104, -91;
/M: SY='C';  M=  20, 128,-107,-100, -92,-103,-101, -88,-100,  36,  35, -98,-112,  30,-103, -92, -90, -86,-115, -98;
/M: SY='K';  M= -84,-101,  10,  10,-105, -90, -86, -99,  70,-104, -97,  55, -95, -76, -74,  62, -78,   4,-112, -97;
/M: SY='F';  M= -99,-102,-115,-112, 107,-114,-100,  41,-107, -69, -76,-107,-112,-112,-106,-102, -93,  32, -79,  29;
/M: SY='V';  M= -86, -99,  38, -98, -86,-112,-110,  41,-102, -72, -75, -99,-106,-103,-105, -96, -83,  95,-117, -92;
/M: SY='K';  M=  31,  78, -90, -80,-105, -96,  67,-107,  90,-103, -94, -82, -98, -78, -68, -85, -88,-100,-109, -93;
/M: SY='G';  M=  60,-101, -95,-100,-110,  90,-100,-110, -97,-109,-100, -84, -98, -94,-103, -76, -92,-100,-104,-105;
/M: SY='D';  M= -97,-109, 118, -64,-116, -92, -81,-114, -84,-114,-111,  54, -98, -83, -92, -84, -85,-112,-132,-101;
/M: SY='F';  M=  19,  82,-114,-109, 113,-106,-100, -85,-106, -77, -85,-103,-114,-113,-106, -96, -94, -86, -80, -60;
/M: SY='M';  M= -92,-101,-107, -94, -83,-105, -84, -69, -91,  22, 136, -97,-102,  63, -90, -97, -91, -76,-103, -82;
/M: SY='K';  M= -93,-110, -84, -70,-110, -99,  79,-109,  89,-104, -91, -77, -95,  87, -62, -84, -90,-107,-106, -88;
/M: SY='M';  M= -90, -99,-114,-103, -81,-106, -86, -63, -97, -59, 149,-101,-101, -89, -95,-100, -89,  11,-105, -81;
/M: SY='P';  M= -94,-117,  38, -81,-115, -96, -96,-105, -91,-114,-102, -93, 122, -93,-102,  13, -86,-108,-112,-110;
/M: SY='F';  M=-102,-102,-115,-111, 117,-112, -93, -76,-106, -72, -80,-106,-115,-113,-104,-102, -95,  10, -71,  56;
/M: SY='P';  M= -93,-115,  47,  86,-115,-101, -89,-110, -80,-110,-103, -87,  90, -77, -91, -89, -89,-109,-113,-106;
/M: SY='D';  M= -95,-112, 105,  68,-116, -98, -84,-115, -81,-112,-109, -72,  19, -78, -90, -86, -88,-111,-123,-102;
/M: SY='N';  M= -88, -97, -68,   6,-107, -81, -76,-106, -79,-112,-100, 120,-100, -78, -87,  41, -75,-106,-122,-101;
/M: SY='T';  M= -77, -92, -87, -89,-100, -90, -94, -94, -87, -98, -94, -76, -91, -86, -94,  75, 101, -86,-116, -96;
/M: SY='F';  M=-105,-102,-116,-113, 124,-112, -94, -79,-107, -71, -81,-106,-116,-116,-104,-103, -97, -85, -69,  42;
/M: SY='D';  M= -98,-111, 125, -61,-118, -94, -83,-116, -85,-115,-114, -65, -97, -84, -93, -86, -87,-113,-133,-100;
/M: SY='V';  M=  44,  55,-100, -96, -91,  30, -99, -79,  32, -89, -86, -93,-103, -93, -92, -85, -86,  59,-103,  33;
/M: SY='V';  M=  68, -95,-106, -99, -91, -96,-108,  11, -99, -78, -78,-101,-103, -99,-103, -84, -82,  81,-111, -95;
/M: SY='Y';  M= -98,-109, -98,-102, -53,-106, -70, -87, -94, -84, -81, -98,-109, -91, -93, -91,  36, -90, -61, 135;
/M: SY='A';  M=  79, -95, -95, -88,  41, -84, -94, -95, -90, -95, -91, -88, -98,  36, -93,  54, -80, -87,-100, -88;
/M: SY='I';  M= -96,-107,-116,-114,  42,-120,-113, 109,-109, -63, -67,-106,-105,-107,-112,-104, -90, -52, -97, -79;
/M: SY='E';  M= -92,-111, -66, 110, -93,-106, -80,-108, -74,-102, -98, -89, -89, -67, -83, -88, -91,-104, -95,  65;
/M: SY='A';  M=  90, -92, -94, -89,-105, -79, -96, -98, -91,-100, -94, -86, -95, -86, -95,  65, -76, -86,-108,-100;
/M: SY='T';  M= -84, -92, -91, -93, -91,-101, -98, -83, -90,  24, -82, -81, -92, -93, -97, -70, 114, -78,-115, -93;
/M: SY='C';  M= -89, 130,-106,-100, -96,-108,-107,   8,  41, -88, -88, -96,-111,-101, -94, -94, -88,  48,-119,-101;
/M: SY='H';  M=-100,-111, -86, -86, -84,-102, 147,-109, -89, -95, -83, -76,-102, -79, -84, -90, -97,-110,-107,  66;
/M: SY='A';  M=  90, -95,-102, -95, -96, -87, -99,  40, -95, -82,  66, -95, -98, -91, -99, -78, -84, -73,-105, -95;
/M: SY='P';  M= -96,-122, -97, -85,-116, -98,-100,-104, -93,-114,-100,-103, 132, -96,-105, -94, -89,-109,-109,-113;
/M: SY='D';  M= -89,-103,  74, -74,-108, -91, -85,-102,  66,-107,-100,  57, -97, -79, -76,  37, -81,  -4,-116, -98;
/M: SY='L';  M=   1, -99,-108, -99, -76,-109, -97, -68,  30,  87, -64,-105,-109, -94, -93,-100, -91, -74,-102, -86;
/M: SY='E';  M= -91,-110,  51,  91,-101,-103, -83, -99, -77,-100, -96, -84, -92,  52, -84, -87, -89,   8,-105,  34;
/M: SY='G';  M=  20,-105, -86,  39,-111,  82, -95,-114,  42,-110,-101, -82, -95, -84, -87, -80, -93,-106,-105,-104;
/M: SY='V';  M= -86,  51,-114,-108,  42,-113,-111, -56,-106,   1, -73,-108,-111,-109,-107, -98, -84,  94,-107, -83;
/M: SY='Y';  M= -99,-109,-104,-105, -56,-109, -73,  30, -97, -75,  78,-102,-110, -92, -95, -98, -93, -80, -67, 125;
/M: SY='K';  M=  -2,-101, -87, -81,-108,  33, -91,-108,  84,-108, -98, -78, -94, -77, -71,  62, -81,-101,-105, -98;
/M: SY='E';  M= -90,-111, -61, 118,-114,-106, -83,-115, -71,-107,-103, -87, -85, -64, -81, -87, -91,-107,-110,-104;
/M: SY='I';  M= -93,  70,-115,-113, -82,-118,-115, 104,-108, -66, -69,-105,-106,-107,-112,-102, -88,  14,-107, -90;
/M: SY='Y';  M=-100,-109,-101, -95,  70,-107, -75, -87, -92, -82, -81, -98,-111,  63, -90, -94, -95, -92, -65, 117;
/M: SY='R';  M= -96,-112, -92, -80,-106,-106, -83,-112,  33,-105, -94, -85,-104, -70, 117, -91, -94,-106,-105, -93;
/M: SY='V';  M= -83, -97,-113,-107, -83,-115,-116,  19,-105, -69, -72,-108,-109,-107,-107, -97, -81, 106,-117, -91;
/M: SY='L';  M= -95, -99,-114,-106, -72,-115, -98, -61,-107,  89,  49,-112,-112,-100,-104,-106, -92,  12,-103, -84;
/M: SY='K';  M= -93,-107, -85, -71,-109,-100, -88,-109, 116,-108, -96, -78, -93, -69, -54, -87, -87,-105,-102, -95;
/M: SY='P';  M= -96,-122, -97, -85,-116, -98,-100,-104, -93,-114,-100,-103, 132, -96,-105, -94, -89,-109,-109,-113;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='G';  M= -78,-105, -92, -97,-112,  96, -96,-116, -94,-113,-103, -79, -97,  32,-100,  37, -91,-110,-105,-104;
/M: SY='C';  M= -91,  51,-100, -93, -88,-107, -96,   4,  42,  39,  42, -93,-103, -88,  36, -90,  41,   6,-108, -91;
/M: SY='F';  M=-103,-102,-114,-110, 114,-111, -90, -78,-105, -70,  66,-105,-113,-109,-102,-102, -96, -83, -71,  61;
/M: SY='G';  M=  41,-100, -99,-100, -98,  60,-103,  40, -98, -89, -87, -89,-100, -95,-103,  30, -85,  32,-107, -98;
/M: SY='V';  M=   3, -97,-100,-100, -95,  44,-103, -71, -98, -86, -85, -90,-101, -95,-102,  53, -80,  77,-112, -97;
/M: SY='Y';  M= -96,-109, -98,-101, -53,-103, -69, -88, -94, -86, -82, -97,-110, -89, -92,  29, -90, -92, -61, 135;
/M: SY='E';  M= -91,-111,  51, 110,-114,-104, -83,-115, -73,-108,-105, -82, -87, -67, -83, -86, -90,-108,-113,-103;
/M: SY='W';  M=-104,-124,-130,-110, -70,-106,-125, -93,-103,  23, -92,-124,-110,-102,-106,-112,-113,-105, 175, -60;
/M: SY='V';  M= -89,  51,-114,-109, -80,-116,-111,  59,-107,  35, -68,-108,-110,-106,-108,-100, -86,  75,-111, -90;
/M: SY='M';  M= -89,-101, -98, -87, -91,-102, -85, -78,  42, -73, 127, -88, -97,  52, -81, -88,  43, -81,-105, -86;
/M: SY='T';  M= -83,  71, -91, -93, -96, -98, -99, -89, -91,  -9, -88, -81, -94, -94, -98,  12, 108, -82,-118, -96;
/M: SY='N';  M= -94,-106,  84,  65,-113, -92, -79,-112, -78,-112,-106,  85, -95, -76, -87, -82, -84,-110,-123,-102;
/M: SY='K';  M=   1,-105,  66, -71,-111, -94, -86,-109,  93,-109,-100,  30, -95, -75, -66, -84, -86,-104,-110, -98;
/I:         I=-22; MD=-57;
/M: SY='Y';  M=-109,-115,-111,-112,  69,-115, -79, -90,-105, -85, -86,-109,-120,-103,-102,-104,-102, -95, -66, 121; D=-22;
/I:         I=-22; MI=-57; MD=-57; IM=-57; DM=-57;
/M: SY='D';  M=-103,-115, 105, -71,-121,-100, -88,-120,   7,-119,-114,  31,-104, -87,  18, -91, -93,-117,-132,-105; D=-22;
/I:         I=-22; DM=-57;
/M: SY='P';  M=  -4,-113,  21,  50,-117,-100, -93,-114,  42,-115,-106,  29,  57, -83, -87,  10, -90,-110,-117,-108; D=-22;
/I:         I=-22; DM=-57;
/M: SY='D';  M= -97,-111,  88,  41,-118, -98, -89,-116, -87,-116,-112,  48,-100, -85, -96,  10,   9,-112,-130,-106; D=-22;
/I:         I=-22; DM=-57;
/M: SY='N';  M=-101,-109,  77, -83,-113, -94, -85,   8, -88,-112,-105,  99,-107, -89, -97, -86, -87,-105,-132,-106; D=-22;
/I:         I=-22; DM=-57;
/M: SY='P';  M=   1,-111,  15,  38,-110, -98, -94, -97,  42,-104, -97, -91,  97, -84, -86, -89, -87,   7,-110,-104;
/M: SY='E';  M= -88,-106, -68, 103,-107,-105, -88, -99,  12,-100, -97, -86, -88, -70, -81, -84,  36,   8,-111,-101;
/M: SY='H';  M= -97,-111, -77,  54,-101,-102, 144,-116, -84,-100, -87, -75, -96, -74, -82, -88, -96,-113,-127, -72;
/M: SY='R';  M= -93,-109, -93, -82, -88,-105, -83, -89,  51, -93, -86, -88,-103,  59,  71, -89, -90,  32, -93,  66;
/M: SY='K';  M= -93,-108,  74,  39,-113, -97, -83,-111,  75,-110,-101,  31, -94,  30, -71, -84, -87,-108,-113, -98;
/M: SY='I';  M= -90,-103,-109,-108, -82,-115,-112,  98,-104, -67, -70,-100,-102,-103,-108, -93,  47,  34,-108, -89;
/M: SY='V';  M=  39,-100,-102, -93, -89,-102,-100,  37,  41,  24, -76, -97,-103, -90,  20, -90, -86,  43,-106, -92;
/M: SY='Y';  M= -94,-110, -91, -83, -80,   3,  79, -96,  16,  -3, -83, -86,-102,  85, -80, -88, -94, -99, -87,  87;
/M: SY='H';  M=   4,-105, -84,  36,  41,  57,  79,-106, -88,-100, -94,  25, -98,  36, -91, -83, -93,-104,-103, -84;
/M: SY='I';  M= -95,-107,-116,-113, -77,-120,-113, 107,-109,  26, -64,-107,-105,-105,-111,-104, -89, -52,-103, -86;
/M: SY='E';  M= -90,-111, -61, 118,-114,-106, -83,-115, -71,-107,-103, -87, -85, -64, -81, -87, -91,-107,-110,-104;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='Y';  M=  20,-102,-106,-100, -77,-107, -93,  38, -90,  20, -74,-101,-107, -93,  43, -94, -88,  49, -94,  66;
/M: SY='G';  M=  31,-104, -93, -99,-109,  93,  67,-115, -97,-110, -99, -81, -98, -93,-101, -79, -95,-107,-107, -99;
/M: SY='D';  M= -96,  82,  97, -73,-110, -94,  68,-113, -87,-109,-103,  58,-102, -86, -93, -85, -87,-109,-132, -96;
/M: SY='G';  M=  28,-101, -93, -99,-110,  89, -98,-112, -96,-111,-102, -80, -97, -91,-102,  49, -87,-103,-106,-104;
/M: SY='M';  M= -93,-102,-115,-109, -77,-115,-103,  73,-106,  51,  78,-108,-107,-101,-106,-103, -89,  27,-104, -85;
/M: SY='P';  M= -93,-119, -96, -85,-115, -96, -99,-104, -92,-114,-100,-100, 128, -95,-104,  13, -86,-108,-110,-112;
/M: SY='H';  M= -87,-105,  50, -77,-109,  30,  68,-111,  49,-109, -98,  30, -96,  32, -79,  41, -84,-108,-114, -93;
/M: SY='M';  M= -94,-100,-114,-106, -76,-112, -93,  38,-103,  61, 117,-106,-106, -95,-101,-104, -91, -67,-103, -82;
/M: SY='H';  M= -89,-105, -97, -94,  11,  22,  79, -83, -82, -89, -85, -88,-104, -86,  61,   8, -89,  52,-103,  27;
/M: SY='T';  M=  -2, -97, -89, -85, -99, -92,  36, -96,  40,  -6, -90, -80, -95, -81,  17,  61,  65, -90,-111, -92;
/M: SY='Q';  M= -93,-107, -98, -88, -82,-106, -89,  38,  11,  13, -78, -94,  30,  63,  10, -90,  17,  -4, -93,  62;
/M: SY='M';  M=  32,  50,   8, -90,-100,   1, -94, -89,   4, -91,  66, -84, -98, -87, -92,  58,  18,   1,-111, -96;
/M: SY='E';  M= -88,-106,  64,  81,-108, -99, -87, -97,  13,-101, -99, -80, -92, -74, -84,  30, -84,  23,-115, -99;
/M: SY='I';  M=  52,  51,-105,-103, -83,   6,-100,  55,-100, -80, -80, -98,-104, -98,-103, -87, -87,  36, -97,  54;
/M: SY='E';  M=  27,-104, -85,  68, -95,-104, -92,  14, -79,  23, -82, -94, -98, -79,  52, -89, -89,   5,-107, -94;
/M: SY='A';  M=  59, -99, -81,  56,-106, -89, -90, -95,   2, -99, -93,  30, -94,  25, -86,  30, -81,   6,-110, -99;
/M: SY='A';  M=  91, -92, -98, -91,-100, -84, -97, -89, -92, -89,  66, -90, -96, -89, -96, -73,  44, -80,-107, -97;
/M: SY='M';  M=  68, -96,-107, -99, -85, -95, -96,  11, -98,  45,  88,-100,-102, -93,-100, -87, -87, -73,-104, -89;
/M: SY='K';  M= -92,-108, -78,  67,-107,-103, -88,   6,  96,-102, -94, -82, -91, -69, -63, -88, -88, -97,-105, -97;
/M: SY='K';  M=   5,-102, -81, -77,-108, -90, -84,-106,  85,-107, -96,  66, -96,  33, -67,  30, -81,-102,-108, -97;
/M: SY='W';  M=  54,  39,-110,-102, -87, -98,-112, -68,-100, -83, -83,-104,-105,-101,-104, -89, -86,  77, 107, -86;
/M: SY='G';  M= -81,-107, -86,  43,-113, 100, -97,-120, -93,-114,-105, -81, -96, -89,-101, -80, -97,-113,-105,-107;
/M: SY='F';  M=-103,-101,-117,-112, 120,-111, -95, -76,-106, -68,  78,-106,-113,-112,-104,-104, -96, -82, -75, -53;
/M: SY='E';  M= -92,-112, -70,  97, -97,-102, -82,-107, -77,-104, -98,  25,  57, -72, -86, -88, -90,-105, -99,  54;
/M: SY='V';  M= -87, -99,-114,-108, -80,-116,-112,  51,-106,  25, -68,-109,-109,-106,-107, -99, -84,  89,-112, -89;
/M: SY='V';  M= -89,-102,-103,   4, -83,-113,  67,  56,-100,  18, -71,-100,-105, -97,-101, -97, -87,  73,-112, -86;
/M: SY='H';  M= -93,-108, -84,  59, -90,-105,  77,  29,  38, -91, -87, -87, -96, -79, -83, -89,  21,  -5,  75,  27;
/M: SY='E';  M=  41,-104, -79,  69,-108, -94,  51,-107, -74,-103, -95, -84, -94,  25,  48,  32, -86, -99,-110, -95;
/M: SY='E';  M= -93,-107,  20,  78,  25,-103, -86, -99,  66, -93,  66, -84, -92, -73, -74, -90, -90, -98,-103, -89;
/M: SY='D';  M= -96,-108, 113,  13,-116, -92, -81,-114, -82,-114,-110,  57, -97, -81, -91, -83, -85,-112,-130,-101;
/M: SY='L';  M= -95, -99,-114,-107, -71,-116,-100, -60,-108,  93, -59,-113,-114,-101,-105,-106, -92,  12,-102, -84;
/M: SY='A';  M=  79, -94, -86,  43,-105, -86, -95, -97, -87, -98, -93, -86, -92, -83, -93,  10,  56, -86,-109,-100;
/I:         I=-30; MD=-77;
/M: SY='D';  M=-109,-126,  73,  43,-131,-115,-100,-127, -95,-124,-119, -91,-110,  51,-102, -99,  13,-123,-135,-116; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='K';  M= -88,-103, -79,  54,-104, -99,  47, -99,  56,-100, -93,  15, -93, -75,  21,   7,  47,  -3,-112, -94;
/M: SY='D';  M= -93,-107,  72, -81, -92,  22, -83,-104, -88,-105, -99,  55,  53, -88, -95, -83,  21,-104,-100,  65;
/M: SY='N';  M= -85,-104,  60, -82,-111,  34, -87,-109, -87,-113,-104,  65,  53, -85, -95,  56, -80,-107,-117,-103;
/M: SY='P';  M=  -3,-108, -81,  53,-105, -95, -91,  28, -85,-100, -94,  56,  84, -83, -95,  12, -84, -91,-111,-103;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='L';  M= -94,-103,-101,   8, -83,-111, -94,  30,  13,  56,  50, -99,-105, -87,  48, -99, -91,   7,-104, -88;
/M: SY='P';  M=  31,-114, -97, -85,-113, -95, -97,-103, -85,-110, -98, -99, 117, -91,  36, -88, -88,-103,-108,-108;
/M: SY='W';  M=-104,-119,-114,-107,  54,-101,-112, -98, -99, -95, -98,  44,-109,-101,-103,-104,-106,-109, 168, -59;
/M: SY='W';  M=-102,-117,-103,-101, -60,-105,  79, -95, -96, -90, -86,-100,-110, -91, -94, -99,-101,-102, 129, 115;
/I:         I=-8; MD=-19;
/M: SY='Y';  M=-106,-118,-103,  31, -68,-116, -86, -92,-101,  23, -86,-111,-115, -95,-101,-105,-103, -97,  79, 107; D=-8;
/I:         I=-8; MD=-19;
/M: SY='P';  M=-100,  82,-109,-101,-103,-110,-107, -96,-105,-105,-100,-110,  99,-108,-113,-102, -96,  23,-112,  30; D=-8;
/I:         I=-8; MD=-19;
/M: SY='L';  M=-106,-108,-123,-116,  53,-123,-107,  15,-116,  75, -70,-119,-121,-112,-113,-114,-101, -77,-100, -81; D=-8;
/I:         I=-8; MD=-19;
/M: SY='D';  M=   4,-105,  72, -84,-115, -94, -96,-111, -94,-113,-109, -80,-101, -91,-101,  68,  39,-103,-126,-105; D=-8;
/I:         I=-8; MD=-19;
/M: SY='G';  M=  31,-108, -94,-100,-116,  66,-100,-117,  11,-117,-107,  45,-105, -94, -99,  15, -93,-109,-115,-110; D=-8;
/I:         I=-8; MD=-19;
/M: SY='D';  M=-118,-134,  61,  37,-141,   6,-110,-141,-108,-139,-133,  25,-121,-105,-117,-109,-114,-137,-146,-129; D=-8;
/I:         I=-8; MD=-19;
/M: SY='W';  M=-122,-131,-136,-130,-103,-139,  47,   9,-130,  35, -95,-130,-135,-124,-128,-129,-119,   8,  63,-105; D=-8;
/I:         I=-8; MD=-19;
/M: SY='R';  M=-116,-129,-118,-111,  21,-125,-115,-126,  29,-123,-119,-109,-125,-105,  45,  13,  14,-122,-126,-110; D=-8;
/I:         I=-8; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='F';  M= -13,-128,-140,-135,  51,-137,-129,  38,-133,  17, -96,-133,-136,-132,-133,-126,-118, -93,-117, -98; D=-8;
/I:         I=-8; DM=-19;
/M: SY='T';  M= -84, -99, -90, -95,-107, -94, -97,-101, -92,-106,-101,  27, -98, -91, -99,  68,  89, -94,-123,-102; D=-8;
/I:         I=-8; DM=-19;
/M: SY='P';  M= -94,-111,-107,-101,  10,   6,-105,   8, -93, -93, -91,-101,  57, -99,  43,  10, -92,  48,-112, -97; D=-8;
/I:         I=-8; DM=-19;
/M: SY='F';  M=  -3,-105,-120,-113,  86,-114,-102, -76,-110,  21,  78,-111,-116,-110,-108,-105, -98,   9, -93, -72; D=-8;
/I:         I=-8; DM=-19;
/M: SY='R';  M=-104,-114,-103, -92,  53,-114, -93,-102,  39,  -3, -92, -96,-112, -85,  89,-100,-100,-102,-101, -85; D=-8;
/I:         I=-8; DM=-19;
/M: SY='M';  M= -96,-104,-108,-104, -91,-110,  52, -79,-100,  -3, 123, -97,-104, -94,-100, -95,  55, -83,-115, -88; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M= -88,-106,-100,-101,-100,  29,-107,-105, -98,-107,-103, -89,-101, -97,-104,  49,  75,-101, 107, -92; D=-8;
/I:         I=-8; DM=-19;
/M: SY='R';  M=   1,-111,-102, -97, -95,   6,  51, -99, -82,  23, -89, -95,-110, -89,  71, -93,  13, -98,-107,  23; D=-8;
/I:         I=-8; DM=-19;
/M: SY='V';  M= -95,-105,-117,-113, -86,-120,-115,  53,-110,  33, -74,-111,-112,-109,-112,-102,  20,  65,-115, -94; D=-8;
/I:         I=-8; DM=-19;
/M: SY='G';  M=  46,-105, -99,-103,-115,  74,-104,-115,-101,-114,-106, -88,-103, -97,-107,  41, -91,-105,-112,-109; D=-8;
/I:         I=-8; DM=-19;
/M: SY='R';  M= -96,-113, -97, -89, -95,-105, -87,-111,  38,-107, -98, -90,-108, -81,  82,  40, -92,-107, -98,  61; D=-8;
/I:         I=-8; DM=-19;
/M: SY='W';  M=-106,-121,-114,-102,  47,-111,-102, -98, -96,  -7, -94,-111,  57,  20,  19,-105,-105,-104, 120,  39; D=-8;
/I:         I=-8; DM=-19;
/M: SY='I';  M= -98,-109,-116,-109,  11,-121,-109,  54, -97,  23, -77,-110,-114,-103,  43,-106, -95,  52,-110, -90; D=-8;
/I:         I=-8; DM=-19;
/M: SY='T';  M= -95,-103, -96,-103, -95,-107,-102,  55, -98,  -2, -85,  52,-103,-100,-105, -85,  80, -77,-119, -98; D=-8;
/I:         I=-8; DM=-19;
/M: SY='H';  M= -96,-111,  50, -85,-111,   7,  94,-115,  12,-110,-101, -80,-103, -87,  16,   8,  35,-110,-125, -93; D=-8;
/I:         I=-8; DM=-19;
/M: SY='H';  M= -10,-110, -92,   5, -97,   6,  79,   5,  15, -99, -93,  26,-105, -89, -92,   7, -92,   6,-110,  33; D=-8;
/I:         I=-8; DM=-19;
/M: SY='M';  M= -93,-103,-109,-106,  69,-107,-102, -80,-103, -82,  70, -98,-108,-103,-105,  34,  47,  31,-102, -80; D=-8;
/I:         I=-8; DM=-19;
/M: SY='V';  M=   4,-104,-115,-111, -91,-115,-118,  56,-108, -77, -79,-108,-110,-109,-112, -96,  21,  75,-118, -97; D=-8;
/I:         I=-8; DM=-19;
/M: SY='Q';  M= -87,-107, -90, -80,-108,  46, -89,-100,  51,-101, -92, -82, -98,  77,  48, -83,   6,   5,-105, -96;
/M: SY='M';  M= -93,-101,-110,-106,  22,-112,-101,  67,-103,  37,  78,-102,-104,-100,-104, -96,  36,   0,-101, -81;
/M: SY='M';  M=  31, -99,-111,-103, -78,-105, -97,  31,-102,  68,  85,-105,-106, -96,-102, -97, -90, -68,-103, -85;
/M: SY='E';  M= -87,-106, -64, 103,-111, -97, -83,-112, -74,-108,-102,  45, -88, -68, -83,  37, -84,-105,-112,-102;
/M: SY='I';  M=  27,-101, -97, -92,  20,-101, -96,  58,  49, -83, -82, -89, -98, -90, -86, -83,  57, -74, -96,  35;
/M: SY='I';  M= -93,-102,-115,-110,  42,-117,-109,  75,-108,  38, -67,-108,-109,-106,-108,-103, -88,  52,-100, -80;
/M: SY='G';  M= -86,-108, -92, -89,-110,  81, -93,-116,  52,-111,-100, -81, -99, -82,  64, -84, -95,-110,-104,-101;
/M: SY='L';  M=  20, -99,-112,-105, -78,-109,-105,  42,-105,  65, -66,-108,-108,-101,-105, -97, -88,  49,-106, -88;
/M: SY='A';  M=  85, -94,-103, -95, -89, -90, -99, -79, -98,  56, -76, -99,-102, -93,-100, -81, -86, -77,-104, -94;
/M: SY='P';  M=   0,-119, -97, -86,-115, -96,-100,-103, -93,-113,-100,-102, 129, -96,-105, -91, -88,-106,-109,-112;
/M: SY='K';  M=  48,-103, -86,   4,-109, -93, -89,-105,  94,-104, -94, -82, -93,  33, -64, -81, -86, -98,-103, -97;
/M: SY='G';  M= -79,-107, -94,-106,-113, 108,-101,-121,-100,-116,-105, -80, -98, -97,-107, -79, -98,-114,-104,-108;
/M: SY='S';  M= -79, -94, -90, -92,  53, -89, -93, -93, -90, -94, -93, -79, -95, -88, -95,  86,  74, -88,-103, -83;
/M: SY='K';  M= -88,-103, -93, -82, -92,-102, -91, -80,  83, -91, -86, -86, -99,  33, -71,  10, -84,  56,-100,  38;
/M: SY='Q';  M= -93,-110,  72,   5,-114, -96, -82,-110,  56,-108, -98,  31, -96,  77,  19, -83, -88,-108,-112, -96;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='V';  M= -84, -95, -93, -97, -91,-101,-100, -65, -93, -81, -81,  56,-101, -97, -99, -81,  72,  82,-120, -94;
/M: SY='H';  M=   4,-102, -87, -90, -99,   3,  75,  28, -81, -95, -89,  55, -99, -83,  48,  12,  35, -89,-114, -90;
/M: SY='D';  M=  -9,-103,  65,  51,-105, -97,  40, -97,  13,-100, -96,  27, -94, -80, -86, -81,  47,   9,-118, -96;
/M: SY='M';  M=  40,-100,-109,-102,  69,-100, -97,   8, -99, -73, 100, -99,-103, -97,-100, -90,  16, -78,  80, -72;
/M: SY='L';  M= -96, -99,-114,-106, -72,-115, -96, -62,-106,  92,  67,-112,-112, -99,-103,-106, -93, -70,-101, -83;
/M: SY='C';  M=  30,  82, -92,  51,  49,-102, -96,  29, -91,  -8, -84, -95,-102,  36, -96, -89, -90, -82,-101, -86;
/M: SY='N';  M= -86,-104,  12, -84,-104,  34, -89,   9,  38, -99, -93,  51, -99,  32,  21,  30, -84,   2,-110, -97;
/M: SY='T';  M=  72, -94, -93, -93,-104,  44, -99, -97, -92, -99, -93, -84, -94, -92, -99, -71,  74, -87,-109,-101;
/M: SY='A';  M=  93, -93, -99, -89,-102, -85, -99, -83, -92, -91, -87, -93, -98,  31, -96, -75, -82,  36,-107, -99;
/M: SY='D';  M= -92,-104,  76,  14,-101, -98, -89,  29,  11, -93, -92,  57, -98, -85, -90, -84,  21,  24,-119, -97;
/M: SY='Y';  M=  20,-101, -92, -97,  26,  58, -88,-101, -94, -99, -94,  18,-100, -90, -97,  56, -84, -97, -91,  62;
/M: SY='L';  M= -97,-100,-115,-108, -72,-117,-101,  42,-108,  90, -59,-112,-112,-101,-106,-107, -92, -65,-101, -84;
/M: SY='V';  M= -81, -96,-104,-101, -88,-106,-108,  13, -99, -75, -77, -96,-103,-100,-103,  29,  44,  90,-116, -92;
/M: SY='E';  M=  25,-107,  21,  63,-111,  34, -88,-111,  10,-106, -98, -83, -94,  37,  44, -82, -91,-103,-108,-100;
/M: SY='G';  M=   0,-105, -95,-105,-112, 105,-101,-118, -99,-114,-104, -81, -98, -97,-106, -78, -97,-111,-104,-107;
/M: SY='G';  M=  41,-103, -95,-102,-111,  97,-101,-114, -98,-111,-102, -82, -98, -95,-105, -77, -94,-105,-104,-106;
/M: SY='R';  M= -94,-111, -78,  70,-109,-105, -84,-113,  54,-106, -97, -84, -95, -68,  89, -89, -92,-106,-106, -96;
/M: SY='M';  M=  20, -99, -92, -83,-100, -96, -89, -91,  58, -90,  78, -83, -95,  25,  19,   1,  61, -88,-107, -92;
/M: SY='G';  M= -86,-108, -84,  40,-111,  75,  47,-115,  51,-110, -99, -80, -95,  36, -81, -82, -94,-110,-106, -98;
/M: SY='I';  M=  19,-103,-113,-108, -79,-111,-108,  91,-106,  47, -65,-106,-106,-102,-108, -99, -89, -57,-103, -87;
/M: SY='F';  M=-104,-101,-117,-112, 120,-113, -98, -75,-109,  25, -76,-108,-116,-116,-106,-105, -97, -81, -74, -53;
/M: SY='T';  M= -77, -93, -89, -91, -98, -91, -96, -85, -89, -94, -91, -78, -93, -87, -95,  78,  88,  24,-116, -95;
/I:         I=-30; MD=-77;
/M: SY='P';  M= -98,-125,-102, -95,-121,  33,-106,-113,-100,-121,-107,-104, 117,-103,-112, -96, -97,-116,-114,-118; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='M';  M=  31, -98,-111,-101, -82,-101, -88, -69, -97,  16, 138,-100,-101, -89, -96, -95, -89, -73,-104, -83;
/M: SY='H';  M= -95,-107,  50, -87,  53,  22,  75, -93, -92, -86,  65, -84,-103,  29, -92, -91, -94, -96, -90,  65;
/M: SY='M';  M= -97,-103,-112,-104,  53,-113, -96,  41, -94,  56,  74,-105,-109, -96,  36,-103, -93, -71, -95, -76;
/M: SY='M';  M= -99,-104,-116,-109,  73,-112, -96,  37,-105,  42,  77,-108,-110,-102,-103,-104, -94, -73,  72,  28;
/M: SY='L';  M= -92, -99,-114,-107, -75,-116,-104,  14,-107,  78, -62,-112,-112,-103,-106,-104, -89,  58,-106, -86;
/M: SY='C';  M=  42, 109,-103,-102,  53,   7,-102, -93,-100, -92, -92, -93,-107,-100,-104,  30, -85,  -2,-104, -88;
/M: SY='R';  M= -91,-109, -84,  44,-107,-101, -84,-111,  42,-106, -97, -83, -98, -70,  96,  29, -88,-105,-107, -95;
/M: SY='K';  M= -93,-107, -85, -71,-109,-100, -88,-109, 116,-108, -96, -78, -93, -69, -54, -87, -87,-105,-102, -95;
/M: SY='P';  M= -96,-119, -95, -82,-115, -98, -98,-105,  42,-113,-100, -98, 124, -90, -91, -92, -89,-108,-108,-110;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 30 in 30 different sequences
Number of true positive hits 30 in 30 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] SAM-dependent MTase Erg6/SMT-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
30 sequences

BOMT_BOTBR  (H2E7T7), ERG6A_GIBZE (I1RGC4), ERG6B_GIBZE (A0A0E0SMA3), 
ERG6_ASPFU  (Q4W9V1), ERG6_CANAL  (O74198), ERG6_CANGA  (Q6FRZ7), 
ERG6_CLAL4  (Q875K1), ERG6_DEBHA  (Q6BRB7), ERG6_EREGS  (Q759S7), 
ERG6_KLULA  (Q6CYB3), ERG6_NEUCR  (Q9P3R1), ERG6_PNEC8  (Q96WX4), 
ERG6_PYRO3  (L7IP31), ERG6_PYRO7  (P0CT10), ERG6_SCHPO  (O14321), 
ERG6_YARLI  (Q6C2D9), ERG6_YEAST  (P25087), PHQN_PENFE  (L0E172), 
SMT1_ARATH  (Q9LM02), SMT1_DICDI  (Q54I98), SMT1_ORYSJ  (Q6ZIX2), 
SMT2_ARATH  (Q39227), SMT2_ORYSJ  (O82427), SMT3B_ARATH (Q94JS4), 
SMTL1_BOTBR (H2E7T8), SMTL2_BOTBR (H2E7T9), SMTL3_BOTBR (H2E7U0), 
SQMT1_BOTBR (H2E7T5), SQMT2_BOTBR (H2E7T6), STRM1_CAEEL (Q9TYP1)
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