PROSITE entry PS51698
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General information about the entry
| Entry name [info] | U_BOX |
| Accession [info] | PS51698 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2013 CREATED;
26-FEB-2020 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51698 |
| Associated ProRule [info] | PRU01034 |
Name and characterization of the entry
| Description [info] | U-box domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=75; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=70; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5493274; R2=0.0088457; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=11980.6113281; R2=1.2929937; PRIORITY=1; TEXT='Heuristic 0.5%'; /CUT_OFF: LEVEL=0; SCORE=673; H_SCORE=12851; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=447; H_SCORE=12559; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-105; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='D'; M= -65,-259, 43, 42,-260, -48, 8, -43, 19, -74,-248, -22, 3, 35, 7, 13, 18, -65,-265,-249; /M: SY='P'; M= -8, -55,-255,-248,-244,-258,-254, 55, -48, -9,-231, -72, 56, -35, 30, -63, -3, 31,-261,-247; /M: SY='P'; M=-248, -9,-253,-242,-250,-255,-250,-241, -30, 24,-239,-256, 112,-248, -34,-249,-243, -27,-257, -3; /M: SY='P'; M= -8, -59, 51, 29,-257,-246, -61, -39, -6,-251, 18, -50, 62, 8,-240, 23, 17, -51,-263, -54; /M: SY='E'; M= -3, -49, 25, 65, 46,-253, 36, 14, -80,-239, -12,-240,-249, -76,-242, -14,-240, -60,-244, 52; /M: SY='F'; M=-248,-249, 8,-250, 108,-255, 0,-225,-248, 21, 52, 20,-259,-251, -79,-247,-241,-231,-229, 6; /M: SY='C'; M=-241, 60, -30,-245, 31,-255, 10, 48, -9, 39, -55, -33,-254, -51, 32, -1, -43, -30,-248, -12; /M: SY='C'; M=-239, 152, 51,-245,-251, -26,-252,-257,-249,-249,-249,-237,-263,-254,-256,-239,-238,-246,-277,-257; /M: SY='P'; M= 27,-256,-241,-234,-258, -69,-245,-249, -57,-256,-245, -51, 116,-239,-247, 31, 6,-247,-257,-254; /M: SY='I'; M= -50,-251,-261,-258,-224,-264,-256, 99,-255, 50,-211,-254,-253,-250,-256,-249, -34, -29,-251,-233; /M: SY='S'; M=-224,-242, -41,-235, -55,-234,-237,-241,-235, -39, 46,-225,-241, 1,-239, 97, 66,-236,-259,-240; /M: SY='L'; M= -49,-250, -21,-240, 11, 42, -17,-107, 28, 54, -18, 5,-251, 3, -11, -20, -91,-235,-247, -3; /M: SY='E'; M= -26,-253, 26, 85, -29, -44,-233,-251, -28, -54,-243,-229,-238, 66,-230, 2, 34,-247,-256,-243; /M: SY='P'; M=-239,-250,-257,-250, -38,-259,-253, 55,-251, 51, -84,-254, 60,-250,-254,-246, -24, 55,-253,-236; /M: SY='M'; M=-241,-249,-259,-250, 55,-253,-236, -49,-245, -67, 141,-248, 34,-240,-245,-247, -26,-224, 20,-222; /M: SY='K'; M= -27, -8, -57, 42,-250,-244, -13, -38, 62, -87,-240, 16, -23, -8, 38, 23, 2, -23,-255, -28; /M: SY='D'; M=-242, 3, 106, 36,-256,-243, 52,-257,-230,-255,-251, 31,-244,-228, -40, -55, -42, -52,-271, -26; /M: SY='P'; M= -16,-267,-244,-233,-263,-244,-247,-251,-240,-260,-247,-250, 134,-243,-252,-239,-236,-254,-256,-260; /M: SY='V'; M=-121, 57,-256, -87,-234,-258, 28, -74,-248,-106, 37,-249,-255, -36, -98,-241, -24, 101,-265,-238; /M: SY='I'; M= -58, 77,-257,-254, -85,-259,-257, 79, -67, -17, -53,-248,-253,-250, -47, -55, 13, 56,-258,-238; /M: SY='T'; M= 33,-243,-248,-245,-233,-245,-247, 13,-244, 48,-222,-241,-248,-241,-248, 40, 49, 31,-256,-238; /M: SY='P'; M= 44, 4,-239, 2, -72,-239,-243, -25, -25,-249,-242,-239, 93, -6, -26, 38, -34, -51,-256,-249; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='S'; M=-228, 50, 62, -32,-253,-235,-236,-251,-232,-253,-248, -36,-243, 0, -41, 88, 44,-244,-265,-245; /M: SY='G'; M= -33,-253,-240,-250,-259, 106,-246,-266, -63,-262,-251, -25,-246,-241, -1,-227,-244,-259,-251,-254; /M: SY='Q'; M=-240,-253, -38, -65, 35,-250, 75, 27, -13, -45, -26, -3,-249, 76, -77, -63, 21, 0,-244, 42; /M: SY='T'; M= -57,-242,-242,-243,-239,-247,-248, 32,-240, -45,-229, -48,-243,-242,-246, 23, 98, 44,-262,-240; /M: SY='Y'; M=-248, -25,-255,-255, 90,-258,-228, -11,-248,-223, 8,-251,-260,-248,-246,-247,-242, -10,-214, 115; /M: SY='D'; M=-240,-258, 94, 92,-262, -15,-231,-263,-225,-258,-255, -34,-238,-221,-235,-233,-236,-257,-266,-250; /M: SY='R'; M= 14,-254,-242,-230, -45, -73,-235, -64, 42, 10,-233,-235,-250, 29, 95,-236,-239, -45,-251,-238; /M: SY='E'; M= -3,-249, -63, 51,-248, -14, -53, -59, -21, -17, -12, -80, -37, -28, 46, 46, 32, -13,-257,-243; /M: SY='S'; M= 41, 36, -48, -58, -1, -14,-239, -33,-240, 11,-233, 41,-248, -58,-244, 44, 19, -27,-250, 22; /M: SY='I'; M=-241,-253,-262,-258, -48,-266,-258, 107,-254, 11, -13,-253,-252, -16,-256,-250,-236, 4,-251,-233; /M: SY='E'; M= -48,-253, -63, 69,-247, -48, -63, -1, 14, 5,-233, -22,-243, 64, -3, -27, -21, 16,-255,-242; /M: SY='K'; M= -18, -40,-230, 45,-255,-246,-235,-248, 63,-116,-242, 13, 50, 31, 43, -34, -39, -12,-255,-246; /M: SY='W'; M=-248, 50,-260,-250, 8,-252, 72,-241,-246,-240,-239,-253,-256, -16,-246,-249,-251, 0, 158, 58; /M: SY='L'; M=-244,-250,-256,-250, 41,-261,-247, 64, 17, 65, -48, -22,-255,-245, -12,-249,-238, -43,-245,-227; /I: I=-31; MD=-79; /M: SY='D'; M= -47,-279, 41, -9, -80, -71, -56,-280, -7, -88,-271, 11,-270, 23, 15, -5, -69,-276,-286,-269; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='K'; M= -20, -37, -19, 22,-246, 3, -51, -40, 56, 20, -10, -8, -23, -57, 31, 22, -21,-240,-254,-242; /M: SY='G'; M= -3,-251, 13, 6, -34, 57, 20,-253, 45,-253,-245, 18,-244, -31, -19, 11, -20, -38, 28,-242; /M: SY='H'; M=-240, 35, 10, -28, 20, -23, 94, -81, -3, -59,-237, 58, -13,-233, -83, -20, 25, -36,-254, 29; /M: SY='G'; M= -45, 16, -12, -35, -19, 46, 10, -3, 18, -38, -49, 40, 21, -6, 17, 12, -19,-243,-255,-242; /M: SY='T'; M=-231,-243,-233, -47, -20,-243, -33, -90, 28,-243,-238, 20, 7, -42, -74, 22, 100, -19,-260,-241; /M: SY='C'; M=-236, 117, 66, -61,-254,-240, 15,-256, -10,-253,-249, 51,-251,-236,-241, 45, -68,-249,-272,-249; /M: SY='P'; M=-241,-265, -39,-233,-259,-245,-246,-248,-240, -37,-245,-247, 130,-242,-251, -6, -32,-252,-257,-257; /I: I=-33; MD=-84; /M: SY='M'; M= -66, -26,-253, -46, 46,-257, -31, 32, 23, -65, 67, -27,-254, -27, -50, -52, -13, 56,-252,-231; D=-33; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='T'; M= -94,-243, 10,-237,-250,-244,-242, -96,-236,-247,-243, 50,-242,-239,-244, -5, 110,-236,-270,-247; D=-33; /I: I=-33; DM=-84; /M: SY='N'; M=-238,-256, -7, -56,-259, 61, -13,-261, 6,-258, 3, 63,-250, 23, 56, -52,-240,-258,-259,-248; D=-33; /I: I=-33; DM=-84; /M: SY='Q'; M= -26,-253,-231, 46,-251, -69, 0,-243, 34, 7, -26,-232,-243, 95, -74, -3, 10, -47,-254,-240; D=-33; /I: I=-33; DM=-84; /M: SY='P'; M= -9,-257,-108, 13,-254,-246, -33, -48, 43,-124, -22,-238, 97, -17, 6, -17, -9, -4,-256,-248; /M: SY='L'; M= -68, -17,-259,-252, 8,-260, -39, -31,-253, 91, -27,-257, -9,-248,-252,-250, -24, -46,-248,-229; /M: SY='T'; M= -81,-248, 37, 3,-248, -72, -27,-244, 1, -43, -58,-227, 42, 3,-237, 59, 66, -52, -11, -25; /M: SY='H'; M= -14,-250, 15, 32, -63, -26, 74, -2, -40, 8, 28, 22, -5, -35, -77, 18, 9,-237,-256, -3; /M: SY='D'; M= -48, -49, 57, 28, 14, -39, 3,-118, 29, -27,-241, -24,-243, -15, -18, 44, 30, -61,-256,-238; /M: SY='D'; M= -79, -28, 71, 2, -65,-118,-233, -34, -63, -23, 15, 39, -73, 41, -60, 44, 26, -42,-262,-242; /M: SY='L'; M=-240, -36, -95, -29, -28,-259,-246, 22,-249, 79, -21, -42,-256, 0,-249, -20,-237, 22, -28, -63; /M: SY='I'; M= -60,-248, -68, -52, -79,-256,-252, 74, -18, -39,-222,-243, -4, -27, -43, -29, 51, 55,-257,-238; /I: I=-42; MD=-106; /M: SY='P'; M= -34,-263, -9, -44,-258,-247, -29, -42, 27, -57,-244,-243, 116,-238, -18, -60, -43, -54,-257,-253; D=-42; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='N'; M=-240,-246, -31,-237, -7,-237, 1, -49, -18, 27,-233, 114,-252,-232,-236, -52,-228, -3,-262,-239; /M: SY='H'; M=-242,-253, -24, -62, -29,-249, 80, -15, 26, 26,-228, 38, 29,-233, 14, -67, -28, 0,-250, 38; /M: SY='T'; M= 37, -28,-238, 32, 40,-243,-244, -15,-238, -8, -65, -42, -42,-237,-244, 28, 59, 8,-251,-234; /M: SY='L'; M= 7,-247, -24,-247,-227, -19, 44, -4,-249, 77, 34, -50,-254,-243,-248, -30,-237, -12,-253,-233; /M: SY='K'; M=-242,-256,-236, -77, -46, -69, -2,-253, 87, -51,-239, -34, -26, -5, 80, -93,-238,-250,-247, 10; /M: SY='N'; M= 4,-248, -19, 23,-248, -54, -63, 20,-106,-107, -2, 64,-244, 32, 5, 51, -2, -12,-259,-243; /M: SY='A'; M= 41,-247, -43, -21, -42, -46,-242, -2, -2, 26, 29,-239,-248, 27, 9, 1, 5, 20,-253,-238; /M: SY='I'; M= -50,-254, -32, 6,-233,-258, -7, 100, -3,-104,-220,-245, -3,-242,-247, -9,-234, 9,-254,-237; /M: SY='Q'; M= -3,-252, 23, -3, -43, 16, 30,-246, 7, -23, -7, 2, 4, 66, -2, 16, -18, -42,-255, -51; /M: SY='E'; M= 20, -23, 14, 56,-254, -56, -1, -75, -2, -92,-242, -5, 11, 18, 41, 16, 11, -54,-258,-245; /M: SY='W'; M=-249,-264, -65, -44, 61,-252, -45,-241,-246, -44,-239,-257, 17, -43, -54, -65, -73,-249, 156, 58; /M: SY='C'; M= -98, 108,-246,-243, -36,-100, 51, -22, 4, 29, -15, -8,-255, -67, 21, 22, -57, -14,-260,-238; /M: SY='D'; M= 3, 46, 47, 42, -37, -46, 13,-244, -2, -9,-239, -42,-245, 33, 2, 8, 5, -16,-259,-242; /M: SY='Q'; M= 2,-252, -20, 36,-252,-244, -66, -77, -5, -82,-241, -3, 50, 55, 22, 8, 46, -51,-256, -23; /M: SY='N'; M= -37,-250,-230, -4,-247, -42, 68, -29, 10, -98,-237, 77,-248, 22, 13, 15, -57, 31, -24, -71; /M: SY='T'; M= -35, -34, 9, -30,-249, 19,-239, -27, 26, -6,-239, 18, -18, 23, 5, 32, 38, -73,-257, -51; /M: SY='Y'; M= -31,-253, -30, -33, 23, -64,-242, 32, -22, -50, 13, 23, 6, -27, -15, 33, -24, 4, 34, 35; /M: SY='K'; M= -2,-257, 31, 19, -87,-107,-240, -39, 36, -4,-241, -22, 28, 24, -17, 12, -54, -33,-256, 9; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 124 in 122 different sequences |
| Number of true positive hits | 124 in 122 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 2 |
| Feature key [info] | DOMAIN |
| Feature description [info] | U-box |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
122 sequences
CHIP_ARATH (Q9SRS9 ), CHIP_CHICK (Q5ZHY5 ), CHIP_HUMAN (Q9UNE7 ), CHIP_MOUSE (Q9WUD1 ), LIN1_LOTJA (C6L7U1 ), LIN2_LOTJA (D1FP57 ), LIN_MEDTR (D1FP53 ), LUBX_LEGPA (Q5X159 ), LUBX_LEGPH (Q5ZRQ0 ), PPIL2_ARATH (Q9FJX0 ), PPIL2_ASPFU (Q4WVU5 ), PPIL2_ASPOR (Q2U5W8 ), PPIL2_CAEEL (P52012 ), PPIL2_CRYNB (P0CP91 ), PPIL2_CRYNJ (P0CP90 ), PPIL2_EMENI (Q5AXT6 ), PPIL2_GIBZE (Q4IBK5 ), PPIL2_HUMAN (Q13356 ), PPIL2_MOUSE (Q9D787 ), PPIL2_NEUCR (Q7RXA6 ), PPIL2_RHIO9 (P0C1J1 ), PPIL2_SCHPO (Q09928 ), PPIL2_USTMA (Q4P555 ), PR19A_ARATH (Q94BR4 ), PR19B_ARATH (O22785 ), PRP19_BOVIN (Q08E38 ), PRP19_CAEEL (Q10051 ), PRP19_CHICK (Q5ZMA2 ), PRP19_DICDI (Q7KWK5 ), PRP19_HUMAN (Q9UMS4 ), PRP19_MOUSE (Q99KP6 ), PRP19_ORYSJ (Q9AV81 ), PRP19_RAT (Q9JMJ4 ), PRP19_SCHPO (O14011 ), PRP19_YEAST (P32523 ), PUB04_ORYSJ (Q6EUK7 ), PUB10_ARATH (Q9C9A6 ), PUB11_ARATH (Q8GUG9 ), PUB12_ARATH (Q9ZV31 ), PUB12_ORYSJ (Q5VRH9 ), PUB13_ARATH (Q9SNC6 ), PUB14_ARATH (Q8VZ40 ), PUB15_ARATH (Q681N2 ), PUB16_ARATH (Q9LZW3 ), PUB17_ARATH (Q9C7R6 ), PUB18_ARATH (Q9XIJ5 ), PUB19_ARATH (O80742 ), PUB1_MEDTR (E4NKF8 ), PUB20_ARATH (Q9C8D1 ), PUB21_ARATH (Q5PNY6 ), PUB22_ARATH (Q9SVC6 ), PUB23_ARATH (Q84TG3 ), PUB24_ARATH (Q9SF15 ), PUB24_ORYSJ (Q10FT0 ), PUB25_ARATH (Q9LT79 ), PUB26_ARATH (Q9FXA4 ), PUB27_ARATH (Q9FLF4 ), PUB28_ARATH (Q9LXE3 ), PUB29_ARATH (Q9LSA6 ), PUB2_ARATH (Q5XEZ8 ), PUB30_ARATH (Q058P4 ), PUB31_ARATH (Q9FHN9 ), PUB32_ARATH (Q94A51 ), PUB33_ARATH (Q8GUH1 ), PUB34_ARATH (Q8S8S7 ), PUB35_ARATH (Q9SW11 ), PUB36_ARATH (Q8GZ84 ), PUB37_ARATH (Q683D5 ), PUB38_ARATH (Q9FJP6 ), PUB39_ARATH (Q9STT1 ), PUB3_ARATH (Q8GWV5 ), PUB40_ARATH (Q9FL17 ), PUB41_ARATH (Q0WUF6 ), PUB42_ARATH (Q9CAA7 ), PUB43_ARATH (Q9SFX2 ), PUB44_ARATH (Q9LM76 ), PUB45_ARATH (Q9C7G1 ), PUB46_ARATH (Q3E9F7 ), PUB47_ARATH (Q3E9F6 ), PUB48_ARATH (Q3E9F5 ), PUB4_ARATH (O22193 ), PUB50_ARATH (Q9FGD7 ), PUB51_ARATH (Q9FKG5 ), PUB52_ARATH (Q9FKG6 ), PUB53_ARATH (Q9LU47 ), PUB54_ARATH (Q9LQ92 ), PUB55_ARATH (P0C6E7 ), PUB56_ARATH (Q8GXQ7 ), PUB57_ARATH (Q9SGT1 ), PUB57_ORYSJ (Q0DR28 ), PUB58_ARATH (Q9SGT2 ), PUB5_ARATH (O23225 ), PUB62_ARATH (Q6DBN5 ), PUB63_ARATH (Q58FY4 ), PUB6_ARATH (O48700 ), PUB70_ORYSJ (Q5WA76 ), PUB73_ORYSJ (Q6K762 ), PUB75_ORYSJ (Q10PI9 ), PUB7_ARATH (Q9CAG5 ), PUB8_ARATH (O81902 ), PUB9_ARATH (Q9SRT0 ), RNF37_HUMAN (O94941 ), RNF37_MOUSE (Q925F4 ), SL11_ORYSI (A2ZLU6 ), SL11_ORYSJ (Q0IMG9 ), UBC4_MIMIV (Q5UQ40 ), UBE4A_BOVIN (A5PKG6 ), UBE4A_HUMAN (Q14139 ), UBE4A_MOUSE (E9Q735 ), UBE4A_PONAB (Q5R9G3 ), UBE4A_RAT (Q6P7A2 ), UBE4B_HUMAN (O95155 ), UBE4B_MOUSE (Q9ES00 ), UBE4_ARATH (Q9LF41 ), UBE4_CAEEL (Q09349 ), UFD2_SCHPO (Q9HE05 ), UFD2_YEAST (P54860 ), WSDU1_CHICK (Q5ZMC3 ), WSDU1_DANRE (A0AUS0 ), WSDU1_HUMAN (Q8N9V3 ), WSDU1_MOUSE (Q9D0I6 ), WSDU1_RAT (Q5FVN8 )» more
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| PDB [Detailed view] |
49 PDB
1N87; 1T1H; 1WGM; 2BAY; 2C2L; 2C2V; 2KR4; 2KRE; 2QIZ; 2QJ0; 3JB9; 3L1X; 3L1Z; 3M62; 3M63; 4WZ0; 4WZ2; 4WZ3; 4XI1; 5GM6; 5GMK; 5LJ5; 5MQ0; 5MQF; 5O75; 5WSG; 5XJC; 5Y88; 5YLZ; 5YZG; 5Z56; 5Z57; 6BK8; 6EXN; 6FF7; 6ICZ; 6ID0; 6ID1; 6J6G; 6J6H; 6J6N; 6J6Q; 6QDV; 7A5P; 7ABI; 7DVQ; 7W59; 7W5A; 7W5B » more |