PROSITE entry PS51841

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51841
Entry name [info]	LTD
Accession [info]	PS51841
Entry type [info]	MATRIX
Date [info]	25-OCT-2017 CREATED; 25-OCT-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51841
Associated ProRule [info]	PRU01187

Name and characterization of the entry

Description [info]

Lamin-tail (LTD) domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=121;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=121;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7145427; R2=0.0058888; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1323; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=983; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-44; D=-150; I=-5; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         I=-150; B1=0; BI=-380; BD=-380;
/M: SY='S';  M= -29,-128, -30,   8, -34, -33, -40,-125, -50,-128,-123, -10,  -7,-110, -46,  26,   9, -48,-135, -45;
/I:         I=-150;
/M: SY='R';  M= -47,-118, -46, -28, -22, -16,  -2,-110, -10, -61,-106, -99,  27, -27,  31,  17,  29, -34,  11, -32;
/I:         I=-150;
/M: SY='T';  M=   1,-110,-105,-103,   5,   1,-102, -16,-100, -35,  17, -25,  12,   4, -23,  25,  34, -42,-109,  14;
/I:         I=-20; MD=-51;
/M: SY='S';  M=   2,-110, -34, -16,-113, -41, -13,-108, -45, -67,-103,  -4,   9,  33, -10,  44,  36, -44,-120, -34; D=-20;
/I:         I=-20; MD=-51;
/M: SY='F';  M=  10,   8,-106,  -6,  53, -65,   7,  -9, -59, -39,  -4, -18, -40,  22,-104, -60, -13,   4, -11,   3; D=-20;
/I:         I=-20; MD=-51;
/M: SY='Q';  M=   6,-110, -30,  -9,-113, -20,  36,-107, -17, -60, -98,   2, -43,  70,  -4,  -3,  42, -68,-117,-100; D=-20;
/I:         I=-20; MD=-51;
/M: SY='R';  M=  29,-108,-100,  -4, -52,-102,-100,   9, -43,   7, -91, -20,  22, -91,  42,  26, -32, -36,-113,-100; D=-20;
/I:         I=-20; MD=-51;
/M: SY='S';  M= -14,-110, -97,  -9,-106, -60,  -8, -65, -45,-109,-103, -15,  19,   0, -11,  58,  31, -37,  50,  -4; D=-20;
/I:         I=-20; MD=-51;
/M: SY='A';  M=  53,-106, -31, -23,-106, -32,  -6,-103, -18, -53, -34, -95,   3, -39,-100,  37,  -3, -30,-113,  10; D=-20;
/I:         I=-20; MD=-51;
/M: SY='K';  M= -32,-121,-112,-106, -10,-118,  -4, -42,  51, -19, -35, -52, -35,-103, -97,  -1,  24, -54,  -7,-108; D=-20;
/I:         I=-20; MD=-51;
/M: SY='G';  M=   1, -30, -97, -58,-115,  76,-103,-112, -99,-114,-105,  -5,  23, -21,-107,  -5,  21, -44,-113,-110; D=-20;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='N';  M= -51,   3,  37,  16,-113, -21, -25,-109, -30,-111,-103,  57,  43,   5,   6,  10,  14, -50,-120,-105; D=-20;
/I:         I=-20; DM=-51;
/M: SY='V';  M= -93,-103,-118,-112, -48,-120,-113,  50,-109,  43, -70,-113,-113,-108, -61,-104, -90,  73,-112, -91; D=-20;
/I:         I=-20; DM=-51;
/M: SY='S';  M=  -7, -31, -51,  -6, -46, -40, -31,  33,  22, -15,   4, -50,-102,  -6,   9,  40, -10,   4,-111, -95; D=-20;
/I:         I=-20; DM=-51;
/M: SY='I';  M= -62,-108,-119,-116,   8,-121,-115,  98,-111,  13, -69,-110,-109,-108,-114,-106, -92,   1,-104, -86; D=-20;
/I:         I=-20; DM=-51;
/M: SY='N';  M=  -7,-102, -22,  15,-104, -94, -45, -24,   6, -60, -95,  58,-100,  -9, -19,  52,  15,  12,-117, -99; D=-20;
/I:         I=-20; DM=-51;
/M: SY='E';  M=   0,-108,   9,  98,-108, -35, -85,-108, -75, -52, -98, -42, -30,  20, -12, -21, -52,-102,-108, -18;
/I:         I=-150;
/M: SY='V';  M=   6,  22,-108,-105, -47, -50, -11,  37,-102, -22, -14,-102,-107,-101,-103, -93, -18,  75,-100,  54;
/I:         I=-12; MD=-29;
/M: SY='D';  M=   6, -24,  68, -38,-114,-105,  13,-111, -42, -17,  -5, -12,-110,  12, -49,   3,  -7,-108,-127, -40; D=-12;
/I:         I=-12; MD=-29;
/M: SY='P';  M= -32, -13, -37, -23,-104,-115,  13, -30,-108, -32, -15,-109,  59,  -5,-112,  -1, -49,  18,-116,  30; D=-12;
/I:         I=-12; MD=-29;
/M: SY='D';  M= -70,-126,  50,  35,-125, -67,-106,-121, -16, -73, -28,  -1,-115,  -1, -19, -16, -42, -33,  26,-115; D=-12;
/I:         I=-12; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='S';  M= -19,-129, -53,-122, -50, -32,-122, -27, -47, -77,-115, -14,  -2,-120,-125,  14, -33,  10,-130,  11; D=-12;
/I:         I=-12; DM=-29;
/M: SY='N';  M= -20,-132, -32,  19, -40,   7,  -9,-129, -65, -76,-123,  29,-126, -44, -67, -68, -42, -49,-134, -16; D=-12;
/I:         I=-12; DM=-29;
/M: SY='G';  M= -38,-134, -59, -16,-138,  54,-122,-140,-114, -77,-127,-110, -31,  -8,  -1, -24,-120,-134,-134,-130; D=-12;
/I:         I=-12; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='S';  M= -24,-129, -11, -21,-128, -14,-122,-118, -46, -24,-118,-113,   8, -13,-121,  20, -12, -22,-138,-125; D=-12;
/I:         I=-12; DM=-29;
/M: SY='N';  M= -36,-130,  -9, -48, -49,  -2,-112,-127,  -4,-131,-124,  55,-128, -45,-114, -49, -55, -38,-133,   6; D=-12;
/I:         I=-12; DM=-29;
/M: SY='G';  M=   0,-105,  -6, -12,-109,  79, -91,-113, -27,-112,-102,  51,  -2,  10, -96, -31, -61,-108,-107, -19; D=-12;
/I:         I=-12; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='E';  M= -50, -17,  42,  61,-113,-103, -91,-112,  56, -32,-102, -13, -41,  -7,  -9,   1, -91,-108,-115,-103; D=-12;
/I:         I=-12; DM=-29;
/M: SY='W';  M=-106,-114,-115,-111,  83,-110, -99, -92,-105, -88, -92, -11,-116, -29,-105, -33, -23, -51, 122,  68; D=-12;
/I:         I=-12; DM=-29;
/M: SY='I';  M= -90,-102,-115,-110,  -5,-117,-113,  83,-107,  -7, -21,-107,-107,-106,-109,-101, -86,  73,-107, -86;
/I:         I=-150;
/M: SY='E';  M= -52,-107, -42,  85,-105,-105, -42, -26,  16, -67, -93, -86, -92,  -5,  49, -86,  19,   7,-110, -97;
/I:         I=-150;
/M: SY='L';  M= -96,-102,-115,-109,  11,-117,-104,  68,-108,  72, -62,-110,-110,-103,-107, -73, -91,  -3,-100, -82;
/I:         I=-150;
/M: SY='Y';  M= -19,-104, -87,  47,  30,-102,  10,  -1,  28, -63, -87, -89, -98,  -2, -17, -10,  31, -26, -90,  68;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='N';  M= -93, -98, -67, -88,-107, -82, -23,-104, -79,-112, -99, 127,-104, -81, -44, -75, -21, -44,-126,-102; D=-19;
/I:         I=-19; DM=-49;
/M: SY='T';  M= -27,-101, -90, -89, -44, -26,  13,  10,  22, -39, -89,  18,  24, -11,  -5,  23,  66, -61,-107,   7; D=-19;
/I:         I=-19; DM=-49;
/M: SY='S';  M= -51,  10,   5, -91,-107,  52,  40,-108, -92,-108,-100, -25, -97, -88, -97,  72,  43,-101,-115, -98; D=-19;
/I:         I=-19; DM=-49;
/M: SY='S';  M=   4,-104,  31,   9,-106,   7, -32,-104,   0, -55, -98,  22,  15,  -2,  21,  34,  22, -64,-111, -24; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='K';  M=   5,-104, -83,  35, -54, -36, -27,-100,  50, -52, -93,  18, -96,  39,  26,  13,  11, -21,-106, -21; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='D';  M=  29,-102,  51,  39,-107, -28, -91, -58, -40,-102, -97, -44,  31, -82,  -4,  26,  38, -18,-114,-100;
/I:         I=-150;
/M: SY='V';  M=  -7,-102, -98,  22, -46,-108, -48,  37, -40, -12,  31, -98,-102,  50, -94, -92, -86,  70,-107, -36;
/I:         I=-150;
/M: SY='D';  M=   1,-103,  92, -48,-110, -89, -84,-105, -84, -70, -15,  56,   2, -26, -48,  37, -49, -64,-122, -99;
/I:         I=-150;
/M: SY='L';  M= -95,-100,-115,-108,   0,-116,-102,  48,-107,  78,  22,-111,-111,-102,-106,-105, -91,  13,-101, -82;
/I:         I=-150;
/M: SY='G';  M= -17,-100,   6, -31,-107,  61, -29,-106,  17,-106, -26, -78, -95, -85, -20,  53,  46, -99,-110, -99;
/I:         I=-150;
/M: SY='G';  M= -18,-105,  40,  -9,-111,  83, -15,-114, -35, -71,-103,  48, -98, -41, -97, -39, -91,-109,-110,-103;
/I:         I=-150;
/M: SY='W';  M=-104,  11,-118,-107,  41,-106,  28, -96,-101, -91, -14,-112,-110,-100,-101,-105,-107,-104, 160,  72;
/I:         I=-150;
/M: SY='R';  M= -89,-105, -48,   9, -49, -40,  -5,  -9,  51, -39, -90, -83, -97,  32,  51,  23,  32, -18,  11, -33;
/I:         I=-150;
/M: SY='L';  M= -95,-102,-115,-109,   6,-117,-104,  64,-107,  67, -12,-110,-110,-103,-107,-104, -90,  26,  -1, -34;
/I:         I=-38; MD=-97;
/M: SY='K';  M= -49,-126, -16,  14,-122,-121, -18,  -9,  36, -76,-108, -31,-116,  30,  15,-105, -14, -13,-128,-113; D=-38;
/I:         I=-38; MD=-97;
/M: SY='R';  M= -57,-130,-114,-102, -25,-125,  12,-114, -12, -49, -34,-108,-124,  52,  61,-109,-113, -16,-120,   4; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='Y';  M=-111,-123,-111, -50,-100,-121, -17, -53,  24, -16, -31,   3,-121,  15, -24, -31, -13,  -1,-112,  53; D=-38;
/I:         I=-38; DM=-97;
/M: SY='V';  M=   7,-101,  12, -24,  -4, -34, -29,  31,   7, -48, -84,  -4, -33, -34, -32,  32, -25,  45,-106,   0;
/I:         I=-150;
/M: SY='D';  M=  -5,-105,  89, -75,-111,  17, -84,-109, -83, -62, -32,  69,   1, -84,  -2, -18, -85,-106,-121,-101;
/I:         I=-150;
/M: SY='G';  M=  -5,-105,  51,  12,-110,  63, -89, -49,  -8,-109,-102,  34, -97, -23,   4,  16, -87,-105,-111,-102;
/I:         I=-150;
/M: SY='G';  M=  19,-102,  23,   3, -14,  30,  -4, -98,  29, -28, -93,   3, -31,   4,   2,  10,   5, -19,-108, -94;
/I:         I=-15; MD=-37;
/M: SY='P';  M=   6,-105, -22,  13,-103,  29, -94, -61, -27, -41, -95, -22,  35, -20,  24,  26,  25, -13,-109, -13; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='E';  M=   5, -25,  -7,  32, -48, -33,  29, -40,  -1, -30, -95,  23,  -6,  15,   0, -20,   0,   2,-117, -99; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='T';  M=  11, -99, -31, -93, -97, -33, -33, -35, -14, -24,  14, -57, -14, -90,  -9,  48,  56,  24,-112, -30; D=-15;
/I:         I=-15; DM=-37;
/M: SY='Y';  M= -23, -15,-104, -38,  64, -76, -24,  10, -95, -43, -82,-100,-109,  20, -22, -27, -55, -12,  57,  93; D=-15;
/I:         I=-15; DM=-37;
/M: SY='T';  M=  -9,-102,   1,  -5, -35, -98, -90, -41,  27, -50,   7, -27, -58,  42,  35,  15,  53,  -7,-108, -37; D=-15;
/I:         I=-15; DM=-37;
/M: SY='F';  M=-100,-102,-116,-110,  89,-115,-100,  36,-108,  56, -69,-109, -27,-109,-107,-105, -50, -55, -86, -21; D=-15;
/I:         I=-15; DM=-37;
/M: SY='P';  M= -38,-110, -16, -26,-110, -41,  15,-104,   1, -56, -99,   9,  95, -89, -52,  36,   9, -60,-114,-104; D=-15;
/I:         I=-15; DM=-37;
/M: SY='P';  M=   2, -29,  22,  -2,-108,  22,  -3,-102,  -8,-106, -99,  -2,  46,   4,  10,  21, -23,  -5,-112, -26; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='N';  M= -56,-136,  24, -65,-137,  -9,  -9, -45,  -5,-136,-127,  34, -16,-110,  14, -56,-116,-132,-143,-127; D=-15;
/I:         I=-15; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='T';  M= -98,-108,-105, -44,  17, -35,   5,   2,-100,   2, -15, -98, -62,  11, -32, -49,  62,  -4,-104,  42; D=-15;
/I:         I=-15; DM=-37;
/M: SY='V';  M= -23,-104, -40, -16, -94,-108,   7,  38, -13,  -9, -23, -42, -25, -97, -47,   4,  41,  45,-116, -96; D=-15;
/I:         I=-15; DM=-37;
/M: SY='L';  M= -95,-101,-115,-109, -22,-117,-104,  65,-108,  73,  -2,-110,-110,-103,-107,-105, -90,  15,-102, -84;
/I:         I=-150;
/M: SY='Q';  M=  36,-106,  -6,  32,-106, -33,   8,-104,  50, -52, -94, -30,  35,  52,   6, -49, -88,-100, -10, -24;
/I:         I=-150;
/M: SY='P';  M=  54,-105, -94, -88,-110,  11, -17,-102, -92,-107, -97, -39,  97, -20, -99,  18, -39, -98,-108,-105;
/I:         I=-23; MD=-58;
/M: SY='G';  M= -84,-107, -90, -67, -71,  85,  53, -41,  -8,-109, -98,  20, -99,  33,  -4, -35, -94, -84,-107, -98; D=-23;
/I:         I=-23; MD=-58;
/M: SY='Q';  M=  32,-104,  14,  45,-111,  18,  12,-107,  18,-105, -97, -81, -94,  63, -54,  17,  -2,-100,-109, -98; D=-23;
/I:         I=-23; MD=-58;
/M: SY='H';  M= -28,-100, -91, -56, -88, -97,  65, -44,   6, -67, -40, -41, -98, -38, -31,  44,  60,  24,-103,  52; D=-23;
/I:         I=-23; MD=-58;
/M: SY='V';  M=  -8, -31, -40,-104,  25,-111,-101,  15, -61,  35, -32,-105,-109,-102, -61, -97, -50,  69, -98,  36; D=-23;
/I:         I=-23; MD=-58;
/M: SY='T';  M= -86, -99, -95, -90, -94,-103, -97, -11,  33,   2, -83, -87, -98, -25,  29,  16,  71,  39,-111, -93; D=-23;
/I:         I=-23; MD=-58;
/M: SY='I';  M= -47,-102,-114,-109,  30,-116,-110,  76,-106,  17, -19,-107,-108, -32,-108,-101, -88,  61,-103, -83; D=-23;
/I:         I=-23; MD=-58;
/M: SY='W';  M=  12,-113,-107, -47, -15,-101,  30, -53, -96, -53, -91, -33,   9, -95, -51, -96, -11, -23, 143,  71; D=-23;
/I:         I=-23; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='A';  M=  60, -95, -50, -91, -99,   0,  40, -16, -91, -19, -26,  22, -97, -88, -95,  30,  50, -60,-111, -94;
/I:         MD=-13;
/M: SY='R';  M=  31,-103,  16, -20,-106,  28, -94,-100,  12, -36, -96,  -9, -40, -28,  37,  25,  -5, -12,-111,-100; D=-5;
/I:         MD=-13;
/M: SY='D';  M=  -5,-106,  44, -29,-109,  39,   8, -57, -17, -60, -28,  37,  -9,  10,  12,  22, -21, -56,-114,-100; D=-5;
/I:         MD=-13;
/M: SY='A';  M=  58,-103,  -9,  -3,-110,  29, -18,-104, -25, -68, -97, -30,  19,  28, -95,   0,  12, -63,-111,-103; D=-5;
/I:         MD=-13;
/M: SY='G';  M= -38,-108,  16, -10,-112,  46,  -4,-109,  27,-110,-102,  18, -30, -29,  16, -18,  39, -42,-115,-103; D=-5;
/I:         MD=-13;
/M: SY='A';  M=  27,-126,-129, -66,  21, -30,  -9, -77, -70, -50, -39,-123, -28,-123,-126, -51, -51,  12,-127, -50; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='S';  M= -60,-128,  -3, -16,-129,-116, -18,-125,-113, -20,-120,  17, -28,  -8,-118,  47, -47,-124,-141,-123; D=-5;
/I:         DM=-13;
/M: SY='P';  M=   2,-113,  29, -50,-114,  -6, -99, -63, -46, -59,-101, -92,  90, -34,   7,  -5,  19,-104,-115,-108; D=-5;
/I:         DM=-13;
/M: SY='P';  M=  17,-109, -16,   1,-108, -17, -98, -98, -22, -67, -12, -12,  76,  12, -98, -21,  34, -10,-113, -36; D=-5;
/I:         DM=-13;
/M: SY='W';  M=  -4,-113,  36,   4, -19, -62, -29,-113, -13,-112,-108,   9,-107, -31,   5,  18,  33,-109,  74, -98; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='D';  M= -34,-123,  47, -17,  -1, -72,-111, -74, -22, -29,-109, -41, -35,   1, -52,  -5, -29,   4,-129,-110; D=-5;
/I:         DM=-13;
/M: SY='L';  M=  -9,-107, -18,-108,  37, -64,-105,  18,-109,  54,   8,-109,   1,-107,-110,-103, -21,   0,-104, -25; D=-5;
/I:         DM=-13;
/M: SY='V';  M= -39,-114, -21,-109, -26,-116,  28, -11,-107, -50, -92,   9,   1,-107, -42, -39, -40,  56,-111,  48; D=-5;
/I:         DM=-13;
/M: SY='W';  M=  18,-117,-112,  -9,  10, -46,-109,-101,-100, -65,  43, -35, -35, -19,   4, -49,  -6, -33, 113, -27; D=-5;
/I:         DM=-13;
/M: SY='D';  M= -44,-110,  47,  -3,-112,   3, -92, -53,  39,-111,-103,  32,-101,  28, -40,   8,  25,-106,-116, -19; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='Q';  M=   3,-121, -17, -10,-118,  -1,-107, -27, -27, -41,-108,   7,-117,  30, -21,  12,-103, -26,-124, -20; D=-5;
/I:         DM=-13;
/M: SY='Q';  M=  -6,-120, -52,  -3,  -8, -66,  15, -47, -92,-113,-105, -16, -57,  77,  -2,   9,   2,-111,-120,-104; D=-5;
/I:         DM=-13;
/M: SY='D';  M=-105, -26,  52,  -7,-121, -80, -18,-120, -57,-122,-117,  35, -55, -98,  -3,  27,   1, -39,-133, -25; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='F';  M= -13,-129,-126, -63,  47, -63,-120, -30,-120, -30, -41, -56,  28, -29, -59, -21, -19,-111,-117, -15; D=-5;
/I:         DM=-13;
/M: SY='S';  M= -34,-106, -96, -93, -22,   7, -98,  -3,  23, -51, -94,  14, -33,  35, -24,  38,  28,   5,-113, -99; D=-5;
/I:         DM=-13;
/M: SY='W';  M= -66,-108,-114,-107,  46,-106,-107, -31,-103,  49, -79,  -3,-110,-101,-104,  -6, -49, -18, 137, -69; D=-5;
/I:         DM=-13;
/M: SY='G';  M= -87,-105,  24, -92, -53,  66, -93,-106, -36, -30, -99,  49,   5, -31, -21,   6,  17, -57,   4,-101; D=-5;
/I:         DM=-13;
/M: SY='F';  M= -23, -15,-119, -41,  40,-120,-119, -15,-115, -16,-101,-113, -59, -24,-119,  10,  28,  -1,  10, -99; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='G';  M= -67,-132,  18, -25,-134,  25, -48, -53, -40,-132,-125, -18,-123,   8,   5,  -2, -39,-129,  -1,-123; D=-5;
/I:         DM=-13;
/M: SY='D';  M=   9,-106,  47,  14,-111,  44, -93, -53, -23,-109,-103,  28,   4, -86, -18,  26, -10, -58,-115,-104; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='D';  M= -49,-106,  89,  -4,-113,  11,  22,-113, -84,-112,-105,  55, -98, -19, -20,  20, -30,-109,-123, -99; D=-5;
/I:         DM=-13;
/M: SY='T';  M=  21,  57, -94,  16, -36,-100, -98,  -8, -91, -22, -20, -16,  -4, -91,  -8, -12,  59,  23,-111, -25; D=-5;
/I:         DM=-13;
/M: SY='R';  M= -57,-134,-120, -20,-128, -51,-121,  -7,  -7,-121,-117, -41,-128,  -2,  28,  -5, -29,  -9,  11,-121; D=-5;
/I:         DM=-13;
/M: SY='T';  M=  10, -98,-103,-101, -89,-105,-105,  41, -98, -10,  39, -95, -33, -98,-103, -46,  70,  47,   9, -92; D=-5;
/I:         DM=-13;
/M: SY='T';  M=  30, -99, -98, -97, -11, -49, -96,  29, -36, -18, -83,  11,-101, -17, -42,  -9,  53,  23,-102,  34; D=-5;
/I:         DM=-13;
/M: SY='L';  M= -98,-101,-111,-107, -41,-115, -99,  -7,-107,  90, -62,   6,-114,-101,-106,-106, -93, -25,-104, -85; D=-5;
/I:         DM=-13;
/M: SY='Y';  M= -56,  11,-102, -45,  25,-108, -27,  -1,   3,  13, -80, -97,-107, -30,  31, -19,  16,  30, -93,  61; D=-5;
/I:         DM=-13;
/M: SY='N';  M= -50,-104,  75, -77,-107, -91, -27,-108,  27, -70,-102,  80,-100, -82,  -1,   4,   6,-106,-119, -14; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='P';  M=  33,-104,  10,  25,-110, -18, -92,-106,  -8,-108,-100,  14,  61, -39, -31,  46,  -5,-100,-112,-103; D=-5;
/I:         DM=-13;
/M: SY='D';  M= -35,-105,  53,  25,-109,  -1,  33,-106,  -1,-107,-100,  45, -13,  10, -31,  15,  33, -48,-118, -98; D=-5;
/I:         DM=-13;
/M: SY='G';  M= -42,-112, -35, -28,-118,  93, -13,-124, -34,-120,-110,  -7,-104, -98, -56, -51,-101,-118,-112,-111; D=-5;
/I:         MI=0; MD=-13; IM=0; DM=-13;
/M: SY='E';  M= -42,-107,   7,  76,-107, -58, -87, -20, -21, -55, -95,  39, -95,  31,  11, -30,  11,  -9,-113, -99;
/I:         I=-150;
/M: SY='E';  M= -20,-105,  -8,  59, -48,-108, -96,  20,  -6,  11, -82, -94, -46,   6,  -8, -91,  -2,  43,-110, -94;
/I:         I=-150;
/M: SY='V';  M= -39, -28,-108,-100, -86,-112, -34,  50,   4,   7, -13,-101,-106, -38,  23, -96, -11,  64,  11, -32;
/I:         I=-150;
/M: SY='D';  M=  66,-100,  77, -46,-110, -44, -42, -60, -89,-105,-100, -79, -97, -25, -47,  29, -13, -94,-116,-101;
/I:         I=-150;
/M: SY='W';  M= -11,-103, -92,   6, -58,  -4,   0, -25, -49, -94,  26,   1, -98,  20,  -1,  40,  41,   7,  82, -89;
/I:         I=-16; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='H';  M= -61,-105, -99, -35,  17,-108,  73, -11, -38,   4,  -2, -25,-106, -91,  24, -59,   5,  39, -96,  62;
/I:         I=-150;
/M: SY='T';  M=   3,-101,  -2, -14,-101,  21, -97,  10, -23, -49, -52, -39, -27,   5,  -6,  22,  60,   2,-112, -98;
/I:         I=-150;
/M: SY='Y';  M= -12,-109,-102, -95,   7, -32,  -9,  -2, -92, -14,   3, -98,  20,  49, -10, -33,  -9,   4,  66,  73;
/I:         I=-150;
/M: SY='T';  M= -17,-106, -51, -44,-102,  14, -97,  10,  13, -41, -91,  23,  21, -12,  19, -19,  35,  14,-112, -41;
/I:         I=-150;
/M: SY='D';  M=  22, -22,  42, -47,   1, -33,  29, -64,  -8,-104, -98, -22,   9,  -8,  30,  16,  26, -64,-113, -55;
/I:         I=-150; E1=0; IE=-380; DE=-380;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	45 in 45 different sequences
Number of true positive hits	45 in 45 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	LTD
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

45 sequences

AV71_ACAVI  (Q17107), IFA1_CAEEL  (P90901), IFA2_CAEEL  (O02365),

IFA3_CAEEL  (Q21065), IFA4_CAEEL  (P90900), IFB1_CAEEL  (Q19289), 
IFB2_CAEEL  (Q19286), IFC2_CAEBR  (Q5WN60), IFC2_CAEEL  (Q21067), 
IFD1_CAEEL  (Q86DC6), IFEA_ASCSU  (P23730), IFEA_CORAP  (P22488), 
IFEA_HELPO  (P16274), IFEB_ASCSU  (P23731), IFP1_CAEEL  (Q09501), 
LAM0_DROME  (P08928), LAMC_DROME  (Q03427), LMN1_CAEEL  (Q21443), 
LMN1_HYPEX  (A0A125S9M4), LMN2_HYPEX  (A0A125S9M5), LMNA_CHICK  (P13648), 
LMNA_HUMAN  (P02545), LMNA_MOUSE  (P48678), LMNA_PIG(Q3ZD69), 
LMNA_RAT(P48679), LMNA_XENLA  (P11048), LMNB1_CHICK (P14731), 
LMNB1_DICDI (Q54HI5), LMNB1_HUMAN (P20700), LMNB1_MOUSE (P14733), 
LMNB1_RAT   (P70615), LMNB1_XENLA (P09010), LMNB2_CHICK (P14732), 
LMNB2_HUMAN (Q03252), LMNB2_MOUSE (P21619), LMNB2_XENLA (P21910), 
LMNB3_XENLA (P10999), LMTD1_HUMAN (Q8N9Z9), LMTD1_MACFA (Q4R899), 
LMTD1_MOUSE (Q9D4C1), LMTD2_HUMAN (Q8IXW0), LMTD2_MOUSE (Q0VET5), 
NF70_DORPE  (Q01241), OV71_ONCVO  (P31732), YVNB_BACSU  (O34986)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

14 PDB

1IFR; 1IVT; 1UFG; 2KPW; 2LLL; 3GEF; 3JT0; 3UMN; 6GHD; 6RPR; 7CRG; 7DTG;
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