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Entry: PS51846

General information about the entry

Entry name [info] CNNM
Accession [info] PS51846
Entry type [info] MATRIX
Date [info] 20-DEC-2017 CREATED;
20-DEC-2017 DATA UPDATE;
16-OCT-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51846
Associated ProRule [info] PRU01193

Name and characterization of the entry

Description [info] CNNM transmembrane domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=184;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=179;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7000365; R2=0.0064028; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1063; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=594; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-70; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='M';  M= -14,  34,  39,  12,  -8, -29,-146, -33,-145, -58,  54, -10, -53,  -7, -39,  22, -34, -32,-165, -29;
/M: SY='D';  M=  -4,-159,  36, -21,  11,   0,  -9,  14, -34,   8,-141, -16,-158,-146,-152,  30,-142, -47,-161, -22;
/M: SY='M';  M=   6,-152,-154,-148, -13, -12,-148, -18,  -8,  23,  77,-146,  28,-145,-148,  -4,  34, -13,-157,-141;
/M: SY='P';  M= -36,-155,  36,   8,-148, -40,-141,-143,-138, -28,  43, -51,  75,-137, -28,  24,  30, -32,   3,   0;
/M: SY='M';  M= -15,-149, -11, -40,  16,  -3,-146,  22, -45,  40,  53,-146,  -5,-144,-148,-141,  12,  24,  44, -17;
/M: SY='W';  M= -45,-153,-152, -37,  39,  10,-147,  11,-144,  -4,-131,-146, -38,-145, -20, -24,  33,  12, 114,  44;
/M: SY='T';  M=   8,  15,   3,  -2, -22,-149,  -1,  16,-142,  29,  -4, -14,  14,-140,-146, -28,  43,   2,  39,   4;
/M: SY='W';  M= -38,  11,-138,  19,-136,-147,  23,   7, -39,  -8,  52,  14,-147,  69, -34,   6,   4, -62,  69,  33;
/M: SY='I';  M= -13,  -1,-158,-154,   2,  -3,-151,  59,-152,  48,  37,-151,-154,-149,-153,-144, -20,  26,  18, -21;
/M: SY='L';  M=  33, -28,-158,-152, -26, -29,-151,  59,-152,  64,-115,-152, -19,-148,-153,-143,-137, -13,-150,-135;
/M: SY='I';  M=  18,  19,-155,-152,  20,  11,-152,  57,-150,  28,-122,-147,-153,-148,-153,  -9, -20,  38,-151,-134;
/M: SY='I';  M=  24,  32,-154,-151,  36,-150,-150,  72,-149,  26,-121, -11,-153,-147,-152,  21,-133,  -9,-149,-131;
/M: SY='I';  M=  41,  40,-156,-152,  44, -30,-151,  47,-150,  40, -46,-149,-154,-149,-152, -56, -31,  11,-147,-131;
/M: SY='I';  M=  23,  11,-158,-154,  33,  -2,-152,  47,-152,  47,-119,-151,-155,-150,-153,-142,-136,  42,-149,-131;
/M: SY='L';  M=  -9,  67,-159,-152,-124,-157,-147,-115,-153,  88,  -7,-155,-160,-148,-152, -26,-138, -42,-152,-135;
/M: SY='I';  M=   3,-148,-158,-154, -27,-159,-154,  72,-152,  50,-115,-152,-154,-150,-154,-143,   9,  41,-152,-134;
/M: SY='L';  M=  41,  51,-153,-150,   5,  23,-149,-122,-149,  53,-123,-146,-154,-146,-151, -18, -58,  32,-152,-137;
/M: SY='W';  M= -38,   8,-159,-155,  37,   8,-150,  25,-153,  63,  14,-152,-157,-149,-153, -38,-139,  13,  64,-127;
/M: SY='S';  M=  38,-142,-135,-137,-150,   3,   9,-147,-136, -44,-142,  11,-143,-131,-141,  88,  38,-139,-159,-144;
/M: SY='A';  M=  85,-144,-144,-143,-156,  72,-148,-151,-143,-151,-144,-134,-144,-140,-148,-121, -31,-140,-153,-151;
/M: SY='F';  M=-143,-148,-161,-156,  75,-162,-146,  27,-153,  51, -20,-155,-159,-153,-152,-149, -27,  41,-136,  33;
/M: SY='F';  M=  -4,  50,-162,-157, 109,-156,-145, -31,-153, -39,  54,-152,-160,-157,-152,-146,-141,   3,-129,   0;
/M: SY='S';  M=   8,-142,-139,-138,-147,-134,-142,-133,-136,-143,-139,-129,-144,-132, -13,  96,  25,  42,-161,-143;
/M: SY='G';  M=  58,  -1,-145,-147,-151,  80,-145,-147,-144, -45,  56,-134,-146,-140,-149,  -3,-137,-141,-153,-148;
/M: SY='L';  M=  37,-145,-151,-147, -12, -36,-143,  19,-146,  53,  42,-144,-151,-141,-148,  42, -44, -44,-147,  16;
/M: SY='E';  M=-137,-152, -11,  95,-152,-148,-131,-153, -26,-151,-145,  34,-137,   3, -34,-128,  58,-147,-157,   0;
/M: SY='F';  M= -11,-146,-155,-151,  60,-156,  13,  32,-150,  54,  12,-147,-153,-148,-150,-141,  45,  -5,-145,-124;
/M: SY='A';  M=  71,-144,-142,-142,-154,  65,-146,-149,-142,-151,-144,-132,-144,-137,-147,  51,-130, -32,-154,-150;
/M: SY='L';  M=  -4,  14,-158,-151,  14,-158,-147,  62,-150,  67,  -7,-153,-156,  21,-150,-147,-139,-114,-145,   1;
/M: SY='M';  M= -15,-146,-153,-146,  25,-152,-141,  -8,-144,   9, 109,-144,-150,  21,-144, -21,  33,  36,-151,-129;
/M: SY='S';  M=  41,-144,-136,-133,-152,   0,  37,-150,  18,-151,-143,-126,-142,  -6, -12,  78,  31,-142,-158,-142;
/M: SY='L';  M= -15,  -2, -16,-148,  30,-155,-147,  11,-150,  71, -33,-150, -24, -25,-150,   0,-136,  16,-148,-130;
/M: SY='W';  M= -29,-151,  45,-131,-148, -15,-136,-149,-125, -19,-143,  39, -25,-130,  64,  39,  34,-146,  69,-140;
/M: SY='P';  M= -11,-157,   5, -42,-149, -29,-140, -16,  42,   1,  13,-138,  82,-131,  47, -15,-136,-142,-154,-146;
/M: SY='Y';  M=  12,-149,  11, -26, -15,-146,-139,   2,-141,  -9,  27, -19,-150,  29,-143,  31,-132,  47,  39,  50;
/M: SY='R';  M=-140,-157,  29,  62,-152,-150,  -4,-155,  50, -45,-143,-129,-143,-119,  77, -28, -19,-151,-155, -22;
/I:         I=-10; MD=-26;
/M: SY='L';  M=-144,-151,-165,-158,-124,-166,-156,  39,-157,  74,-114,-162,-161,-153,-157,-155,-141,  44,  56,-134; D=-10;
/I:         I=-10; MD=-26;
/M: SY='E';  M=-141,-159,  36,  63,-161,-148,  12,-161,  22,-157,-148,   9,-145,  45,  57,  11,-138,-157,-161,-146; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='Q';  M=  -8,-153,-142,  23, -35,-153,  -8,  18,-138,   0,  13,   7,-151,  67,-141, -37, -25,  37,-151,  27; D=-10;
/I:         I=-10; DM=-26;
/M: SY='L';  M=-145,-151,-158,-154,-122,-162,-143, -10,-150,  76,  16, -11,-161,-147, -22,-150, -18,  14,-146,  46; D=-10;
/I:         I=-10; DM=-26;
/M: SY='Q';  M=  43,-152, -16, -38,-147,-147,  12,  41,   2,-136,  -4,-139,-149,  48,   6,   1, -20,  21,-158,-143; D=-10;
/I:         I=-10; DM=-26;
/M: SY='E';  M= -10,-156, -20,  51,-155, -35,-136, -25,  48, -26,-142,  28,-146,  40,  41,-134, -12,-147,-158,-147; D=-10;
/I:         I=-10; DM=-26;
/M: SY='S';  M=   3,  29,  13,  29,-160,  -5,-141,-158,  11,-157,-150,-131,-146,  28, -31,  68,  -2,-150,-163,-150; D=-10;
/I:         I=-10; DM=-26;
/M: SY='G';  M=-134,-158, -25,   6,-164,  92,   1,-169, -31,-165,-155,  27,-149,   1,-148,-132,-146,-164,-159,-155; D=-10;
/I:         I=-10; DM=-26;
/M: SY='N';  M= -18,-151,  28, -52,-158, -32,-138,-155,   6,-158,-150,  67, -11,-133,  -1,  45,  51,-149,-168,-150; D=-10;
/I:         I=-10; DM=-26;
/M: SY='P';  M=  -2,-156,  28,  37,-155,-146,-139, -12,  38,-149,   8, -30,  64, -18,  16,   3, -21, -43,-159,-148; D=-10;
/I:         I=-10; DM=-26;
/M: SY='A';  M=  45,-150,-136, -62,-156,  22, -19,-154,  32,-153,-144,  24,-146,  36,  38,  27,   5,-146,-157,-146; D=-10;
/I:         I=-10; DM=-26;
/M: SY='A';  M=  67,-149,  29,  61,-156,  -8, -30,-151,  -1, -51,-145,-134, -23,-129,-138, -27, -25,-143,-158,-149; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='K';  M=-145,-160,-142,-131,-153, -30,-139,  10,  79, -33,  12, -16,-151,  28,  63,-141,-142,-145,-156,-145; D=-10;
/I:         I=-10; DM=-26;
/M: SY='K';  M=  42,  15,-144, -39,-149,-146,-144,  -6,  54,   0,-136, -42, -13,  15,  25,  -5,-136, -10,-157,-146; D=-10;
/I:         I=-10; DM=-26;
/M: SY='H';  M=  44, -14, -37,-142, -14, -37,  54, -32,-140,   7,-132, -14,-153,  21,   6, -37, -29,  24,-153,  23; D=-10;
/I:         I=-10; DM=-26;
/M: SY='A';  M=  69,-149,-143,   8,-150,-142,  30,-141,  -1,   6,-136,-140, -10, -18,  22, -63,  -2, -29,-158,-145; D=-10;
/I:         I=-10; DM=-26;
/M: SY='K';  M=  19,-155,-138, -51,-154, -31,  -5,-153,  75,-149,  36, -13,-147,  -6,  72, -64,-138,-148,-154,-143; D=-10;
/I:         I=-10; DM=-26;
/M: SY='R';  M= -11,-152, -26,-141,-133,-157,-143,  16,  30,  50,   8,-146,-154,-136,  53,-144,-139,  21,-151,  -4; D=-10;
/I:         I=-10; DM=-26;
/M: SY='I';  M= -17,-152,-152,-148,-132,-155,-147,  71,-143,  -7,  16, -16, -14,  17,   2,   2, -41,  33,-150,  26; D=-10;
/I:         I=-10; DM=-26;
/M: SY='E';  M=  -6,-151, -19,  57,  44,-149,  -3,-138, -26,  14,  37,   7,-147, -20, -38,  -8,  28,-138,-149, -16; D=-10;
/I:         I=-10; DM=-26;
/M: SY='P';  M=  -1,-160,  33,-131,-157,-146,  81,-153,   2, -45,   8,  25,  83,  -3,  -2,-138,-139,-154,-165,-143; D=-10;
/I:         I=-10; DM=-26;
/M: SY='P';  M= -30,-154,-159,-150,  25,-159,-152,  19,-147,  46,  -3,-156,  61,-149,   9,-149,-140,  38,-152,-136; D=-10;
/I:         I=-10; DM=-26;
/M: SY='R';  M=-141,-156,  52,-132,-155,   6,-138, -47, -30, -58,-144,  39,  -6,  14,  62, -25,   8,  10,-164,-147; D=-10;
/I:         I=-10; DM=-26;
/M: SY='R';  M=-143,  -1,-137,  21, -16,   6,-138, -30,  41,-152,   7,  27,-151, -17,  75, -45, -40,-151,-157,-145; D=-10;
/I:         I=-10; DM=-26;
/M: SY='Y';  M=  -9,-157,-147,-144,  56,-152,  27,-142,  24,   3,-136,  38, -26, -36,  27,-143,-143,-145,  45,  58; D=-10;
/I:         I=-10; DM=-26;
/M: SY='Q';  M= -30,-155,-152,-146, -17,  35,-145,   4,-146,  49,-127,-145,-156,  61,-147,   0,-142, -26,-150,  16; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='H';  M=  -9,-150,-133,-137,-156,  22,  71,-156,-135,-156,-146,  59, -11,  18, -20,  58,  22,-151,-165,-143; D=-10;
/I:         I=-10; DM=-26;
/M: SY='W';  M=  35,  20,-150, -25,  23,-150,  -5,  15,-142,  13,   9,-145,-152,  39, -34, -38,  20, -33,  50,  14; D=-10;
/I:         I=-10; DM=-26;
/M: SY='C';  M=  -5,  71,-158,-154,-135, -38,-154,  23,-150,  46,-123,-151,-158,-150, -20,  -6, -22,  47,-160,-142; D=-10;
/I:         I=-10; DM=-26;
/M: SY='L';  M=-144,-151,-158,-147,-128,-163,-147, -23,-149,  81,-114,-156,-160,  60,-148,-150,-141,  25,-153,-136; D=-10;
/I:         I=-10; DM=-26;
/M: SY='C';  M= -38,  84,-154,-155, -14, -28,-154,  44,-152,  24,-127,  11,-158,-152,-155, -29,  10,  39,-160,-141; D=-10;
/I:         I=-10; DM=-26;
/M: SY='T';  M=   9,-144,-140,-143, -35,  55,-145,-140,-140, -19,  -1,-129,-143,-139,-146,  39,  80, -32,-156,-143;
/M: SY='I';  M=-140,-148,-151,-151, -12,-157,-147,  61,-146,  58,-116,  32,-154,-146, -15,-142,  27,  19,-153,-133;
/M: SY='L';  M=   5,-144,-145,-146,-131,-148,-144,  24,-144,  64,-120,  33,-150,-142,-147,   3,  61,-121,-155,-137;
/M: SY='L';  M= -34,-148,-159,-154, -21,-160,-151,  59,-153,  73,-112,-154,-156,-149,-153, -22, -19,  15,-150,-132;
/M: SY='C';  M= -20,  77,-150,-151,  17,  56,-150,  -3,-148,  13,  -4,-139,-151,-147,-152,  -8,  26,  15,-153,-139;
/M: SY='N';  M=  20,-147,-122, -19,-151,  28,-128,-153,-129,-156,-146, 108,-148, -19, -22,   8,-128,-151,-160,  -1;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='W';  M=  28,   6,-157,-152, -16, -15,-155,  58,-150, -13,  11,-149,-152,-148,-152,  -6,-133,  60,  62,-134;
/M: SY='L';  M=  11,-146,-155,-150,  11, -15,-148,  23,-149,  50,  48,-147,-153,-146,-150, -10,  11,  40,-151,-133;
/M: SY='A';  M=  64,   6,-148, -27, -12,  41,-152,  17,-145,-134,-133,-141,-148,-144,-150,-130, -39,  52,-154,-143;
/M: SY='N';  M=-133,-148, -19,  41,-148,   7,-135,-138,-132, -41,  54,  66, -13,   3,-139,  36,  29,   9,-161,-144;
/M: SY='A';  M=  60,-145,-136,  35,-147,-138,-142,  -9,-136, -17,   5,   7,  14,-133,-142,  36,  29, -12,-157,-145;
/M: SY='T';  M=  47,-144,-143, -24,-138,  -5,-146,  20,-142,  19,-129,-137, -10,-140,-147, -10,  69, -32,-153,  -2;
/M: SY='C';  M= -16,  60,-157,-152,  38, -54,  12,  24,-152,  60,-118,-150,-157,-149,-152,   1,-136,  26,-149,-129;
/M: SY='T';  M=  15,-148,-136,  26,  23, -47,-142,-139, -27,-143,-140,-134,  58, -20, -18,  30,  63,  -1,-154,-140;
/M: SY='I';  M= -33,-152, -24, -51,-133, -13,-146,  51,  13,  39,-123,-145,  31,-140,  22,-142, -35,  20,-151,  -4;
/M: SY='L';  M=  26, -21,-155, -24,  36, -37,-145, -20,-147,  62,  14,-152,-155,-145, -32,-143,-138,  13,  22,  15;
/M: SY='L';  M=  16,-148,-156,-150,  47,  -4,-145,   0,-147,  65,  40,-150,-156,  -7, -18,-144,-139, -14,-144,-127;
/I:         I=-9; MD=-22;
/M: SY='H';  M=   2,-155,  73, -35,-147, -60,  82,-149,-135, -46,  19, -18,-149,  -2,   5, -26,   3, -34,-162,  24; D=-9;
/I:         I=-9; MD=-22;
/M: SY='Y';  M=  18,-155,   9,  -4, -21,  -7,  11,-150,  10,-150,-143, -29,  34,  28,  18,  20, -62, -31,-149,  43; D=-9;
/I:         I=-9; MD=-22;
/M: SY='L';  M=  -4,  -7,-156,-153,  24, -34,  37,  42,-152,  58,-120,-149,-156,-148,-153, -11,   2, -28,-152,-132; D=-9;
/I:         I=-9; MD=-22;
/M: SY='F';  M=  11,-151,-159,-156,  79,  -6,-147,  22,-153,  23,  12,-151,-158,-152,-153, -24, -46,  -8,-137,  31; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='G';  M= -35,-165,-151,-159,-169,  68,-156,-165,-155,-168, -15,  39,  27,-154,-162, -11, -26, -28,-171,-166; D=-9;
/I:         I=-9; DM=-22;
/M: SY='E';  M=-141,-160,  28,  60,   9, -24, -23,-155,-136, -64,-150, -24,  59,   2,-144,  25,   3,-154,  43,-144; D=-9;
/I:         I=-9; DM=-22;
/M: SY='W';  M=  46,-155,  -4, -37,-148,  57,-148,-150,-143,   3,-143,-140, -16,  -7, -14, -41, -45,-147,  59,  -4; D=-9;
/I:         I=-9; DM=-22;
/M: SY='W';  M=  -4,-155,-160,-156, -12,  16,-154,  31,-154,  42,-128,-153,-158,-150,-156,   8,-142,   6,  94,   0; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='L';  M= -37,-152,-161,-155,  29, -29,-149,  31,-154,  46,  24,-156, -27, -25,-154,-149,-140,  45,-145,  34; D=-9;
/I:         I=-9; DM=-22;
/M: SY='A';  M=  73,-147, -23,-139,-156,   7,-146, -35, -23,-151,-144,   7,  15,-138,-145,  40, -21, -50,-159,-151; D=-9;
/I:         I=-9; DM=-22;
/M: SY='F';  M=  30,-150,-163,-156,  69,-156,-154,  27,-154,  26,  13,-156,-158,-154,-155,-146,-141,  34,  64,-123; D=-9;
/I:         I=-9; DM=-22;
/M: SY='V';  M=  48,-148,-154, -30, -28,  -6,-154,  21,-150,  31,-126,-150,-154,-147,-153, -29,-136,  54,-157,-141; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='I';  M= -15,-151, -18,-153,-130, -61,-157,  68,-153,  28, -15,-152,-155,-150,-155, -18,-136,  55,  64,-135; D=-9;
/I:         I=-9; DM=-22;
/M: SY='S';  M= -13,  -3,-151,-148,-140,  -8,-148,  -8,-147,  21,  43,-142,  -9,-142,-150,  67,-130,  41,-160,-143; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='T';  M=  16,-142,-141,-141,-146, -17,-148,-131,-139,-139,-137,-131,-143,  -4,-145,  -8, 101,  34,-164,-145; D=-9;
/I:         I=-9; DM=-22;
/M: SY='F';  M=  11,   1,-151,-149,  47,  -3,-147,  -4,-147,  12, -16,-142,-152,-146,-150,  36,  28,  29,-146,  13; D=-9;
/I:         I=-9; DM=-22;
/M: SY='L';  M=  28,  -7,-158,-153,  -8,  15,-149, -23,-152,  67,  31,-152,-157,-148,-153,-143,-139,  16,-151,-136; D=-9;
/I:         I=-9; DM=-22;
/M: SY='I';  M=-139,  16,-153,-151,  26,-156,  61,  64,-149,  38,  -9, -27,-154,-145,-150,  18,-134,  26,-152,-128;
/M: SY='V';  M=-139,-147,-163,-156,  37,-162,-153,  25,-154,  57,  13,-158,-158,-152,-153,-150,-136,  69,  36,-127;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='V';  M=  -2,-146,-159,-154, -52,-158,-155,  54,-152,  38,   2,-154,-155,-150,-153, -38,-132,  76,-156,-136;
/M: SY='F';  M=-145,   8,-163,-158, 105, -51,-148, -39,-155,  31, -13,-155,-161,-159,-153,-150,-140,  37,-131,-110;
/M: SY='G';  M=  38,  54,-144,-149,-155,  89,-149,-153,-145,-154,-146,-131,-147,-144,-152, -44,   5, -27,-155,-153;
/M: SY='E';  M=-138,-159,  36, 113,-161, -30,-131,-163,-120,-155,-151,-131,-135,-114, -17,-134,-138,-155,-159,-150;
/M: SY='I';  M=-141,-150,-162,-157, -12,-164,-150,  79,-154,  45,  40,-155,-156,-150,-154,-150,-136,  39,-146,  24;
/M: SY='I';  M=  21,  -2,-156,-152,   6, -30,-153,  59,-150,  39, -20,-149,-152,-149,-153,-139,  22,  37,-152,-134;
/M: SY='P';  M=-144,-169,-144,-133,-164,-146,-147,-151,-140,-162,-148,-151, 135,-144,-153,-141,-136,-157,-157,-161;
/I:         I=-45; MD=-115;
/M: SY='K';  M=  -4,-157,-136,-121,-157,-146,-133,-155,  88,-153,-141,-129,-145,  86,  27, -33,-137,-152,-150, -18; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='T';  M=  56,-142,-138,-138,-144,-136,-139, -32,-133, -50,  11,  17,-144,-133,  17,  48,  67,-132,-155,  -1;
/M: SY='V';  M= -36,-148,-160,-155,   8,-161,-153,  61,-153,  50,-114,-155,-156,-151,-154,-147, -34,  61,-149,  -7;
/M: SY='C';  M=  70, 108,-148,-146, -23,  37,-150,-147,-146,-146,-142,-138,-151,-145,-151,  -3,-134, -32,-158,-149;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='S';  M= -27,-148,-144, -38,-139, -28,-143,  37,-135, -21,  38, -16,-148,  -3,  35,  47,   9,  44,-157,-139;
/M: SY='R';  M=  -8,-155,-139,-128, -16,-148,  12,  10,  36, -61, -10, -10,-148,  64,  83, -37, -31,-140,-152,-137;
/M: SY='Y';  M= -39,-154,-136,-139, -11, -36,  77,-142,  26, -61,-134,  60,-152,-132, -18,-135, -20, -34,  45,  94;
/M: SY='P';  M=  55,-151,-141,-141,-156,  59,-146, -37,-141,-152,-144,  15,  76,-140,-149, -23, -36, -43,-155,-152;
/M: SY='E';  M=-142,-153, -19,  71, -12,-157,-137,  10,-132,  57,-124,-143,-147,  22,  10,-142, -33,-130,-148,   4;
/M: SY='A';  M=  67,-146,-137,  -6,-150,-137,  35,-145,  15, -19,  -1,  13, -31,   4,  33,  19, -44,-139,-156,-142;
/M: SY='V';  M=-135,  15,-158,-154, -19,-161,-158,  65,-151,   0,-119,-150,-153,-152,-154,-141,  35,  78,-158,-136;
/M: SY='A';  M=  73,-143,-144,-142,-147,  49,-146,-141,-142,  17,-136,-135,-146,-139,-147,  29,   5,-135,-153,-146;
/M: SY='A';  M=  53,   1,-149,-141, -35, -39,-142,-128,-135,  30,  50,-142,  -5, -10,  38,  -9, -21,   7,-151, -21;
/M: SY='R';  M= -31,-150,-142,-142,  16, -11,  19, -11, -19,  36,-128,  40, -31,-135,  43,  17, -35, -33,  13,  22;
/M: SY='T';  M= -29,-145,-151,-150,  46,   9,-149,  17,-147,  27, -21,-142,-151,-147,-150,  18,  47,  44,-149,-130;
/M: SY='A';  M=  56,  -7,-147, -39,-138, -36,-149,  47,-144,   2,-127,  15,-150, -12,-148,  -4,-132,  37,  41,-140;
/I:         I=-45; MD=-115;
/M: SY='P';  M= -10,  -3,-147,-143,  36,  17, -10, -40,  10, -31,-138, -14,  70,-142, -20, -51, -21, -24,  56,  36; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='P';  M= -15,-153,-156,-149,  37, -34,-151,  48,-150,  44,-122,-153,  75,-149,-154,-145,-137,  13,-148,-133;
/M: SY='V';  M=-135,-146,-152,-148,-127,-156,-145,  10,-146,  41,  48,-146,-152,  -4,-148, -20,  48,  61,-151,  27;
/M: SY='R';  M= -16,-154,-144,-138,-131,  -9,  -1,  21,  -1, -10,-130, -23,-152,   1,  75,-138, -40,  -1,-140,  69;
/M: SY='W';  M= -36,-151,-161,-154,  67, -37,-153,  37,-152,  40,-122,-155,   8,-152,-154, -47,-140,  30,  90,-120;
/M: SY='F';  M= -30,  11,-157,-152,  79,-156,-145,  14,-151,  49,  32,-151,  14,-151,-151, -38,   5, -41,-138,  -3;
/M: SY='M';  M= -13,-148, -24,-145, -11,-148,-134, -25,-143,  19,  93,-142,-151, -24,-144,  42, -33,  11,-139,  70;
/M: SY='W';  M= -51,   6,-151,-142,  35,-156,-140,   9,  39,  39, -21,-145,-154, -17,  27,-143, -12,  -7,  54,  44;
/M: SY='L';  M= -51,-148,-162,-156, -19,-163,-152,  65,-155,  74, -19,-157,-157,-150,-154,-151,-137,  24,-150,-131;
/M: SY='F';  M=  13,  51,-152,-149,  64,-150,-145,-124,-147,  41,  50,-143,-152,-147,-149, -13,  58, -32,-146,-126;
/M: SY='Y';  M= -48,-151,-152,-148,  66,-152,-134,-130, -37,  13,  35,-145,-154,-142, -22,  -1,  33,-133,  73,  88;
/M: SY='P';  M=-144,-169,-144,-133,-164,-146,-147,-151,-140,-162,-148,-151, 135,-144,-153,-141,-136,-157,-157,-161;
/M: SY='I';  M=   0,-149,-161,-156,  43,-160,-154,  74,-154,  48,-115,-155,-156,-152,-155,-147,-136,  32,-146,-128;
/M: SY='A';  M=  49,  -2,-147,-144,-141,  -5,-149,  40,-142, -16,-130,-138,-147,-140, -21,  43,  24,  30,-157,-142;
/M: SY='W';  M= -10,-160,-156,-145,  -1,-151,-140,-139,   5,   4,   5,-151,-155,  -4,  28,-146,-147,-144, 139,  80;
/I:         I=-28; MD=-70;
/M: SY='L';  M= -21,-172,-184,-177,  27,-182,-172, -22,-178,  54,-138,-181, -18,-175,-177,-173,-164, -35,-168,-150; D=-28;
/I:         I=-28; MD=-70;
/M: SY='L';  M=  -8,-171,-180,-176,   7, -38,-168, -27,-174,  39,  27,-174,-179,-171,-174,-166, -20, -32,-168,  -5; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='N';  M=-165,-176,  -1, -26,-174,-168,-157,-163,-154, -50,   8,  65,-175,  -7,  -2, -51, -20,  -4,-191,-170; D=-28;
/I:         I=-28; DM=-70;
/M: SY='P';  M=  14,-157,-147,-141, -12, -17,  -5, -46, -28,  17,-136,   8,  91,-143,-148, -31, -31,-142,  66,  -2; D=-28;
/I:         I=-28; DM=-70;
/M: SY='I';  M= -11,-148,-157,-153, -33,-157,-153,  75,-152,  55,-115,-151,-153,-148,-153,  -1,  -5,  18,-152,-134;
/M: SY='S';  M=  46,-144,-141, -37,-146,  36,-143,-135,-140,  -5,   9,-133,-145, -10,-144,  65, -11,  15,-156,-144;
/M: SY='R';  M=-140,-153,-135,-128,-148, -59,-132, -37,  66,  -6,  36,  45,-147,  40,  69,-134,   1,-143,-154,-140;
/M: SY='L';  M= -31,-149,-154,-149,-128, -35,-148,  48, -31,  64,  11, -12,  14,-144, -19, -46,-136,  19,-153,-136;
/M: SY='L';  M= -36,-147,-161,-155,  69,-161,-148,  14,-154,  76,-113,-156,-159,-152,-153,-150, -33,  -4,-140,-121;
/M: SY='D';  M=   4,  -8,  71, -17,   7,  52,-138,-148, -37, -16,  19,  29,-146,-137,-143,-130,  17,-145,-158,-142;
/M: SY='W';  M=  -5,  26,-148,-139,  11, -24,-142,  22,  39,   8,-131,-141,  14, -24,  50, -28,-138, -33,  56,  19;
/I:         I=-22; MD=-55;
/M: SY='M';  M=   6,  -2,-151, -23,  25,  -4, -14,  24,  10,   8,  46,-145,-154,  -7, -18,-141, -32,  10,-146,  32; D=-22;
/I:         I=-22; MD=-55;
/M: SY='L';  M=   8,-152,-152,  -7,  39,-154,-147, -12, -28,  56,  -8,-151,  40,-144, -15, -16, -33, -49,-149,-133; D=-22;
/I:         I=-22; MD=-55;
/M: SY='G';  M= -18,-156,-140,-140,-159,  76,  -3,-161,  50,-160,-149,  12, -10,-135,  20, -27,-141, -56,-156,-151; D=-22;
/I:         I=-22; MD=-55;
/M: SY='H';  M= -45,-156,  -2,  30, -10, -12,  37, -14,  25,  26,-132,-140,  16,  28, -17, -51,-140,   7,-156,-139; D=-22;
/I:         I=-22; MD=-55;
/M: SY='E';  M= -48,-161,  33,  62,-163,  11,-140,-162,  44, -57,-152,  -5,  11,-128,   9, -11,-141,-158,-163,-153; D=-22;
/I:         I=-22; MD=-55;
/M: SY='H';  M=-152,-164,-156,-154,-149, -35,  52,  16,-151,   4,   8,  17,  32, -20,  -7,-150,   8,  14,-169, -29; D=-22;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='D';  M= -29,-166,  37,  29,-170,  11,-149,-166,  11,-167,-160, -11,-157, -29,  22,  11, -40, -32,-173,-161; D=-22;
/I:         I=-22; DM=-55;
/M: SY='T';  M= -34,-154,  31,  23,-150, -26,-145, -29,-139,  -2,   9,-138,  38,   1, -39,  14,  42,  12,-163,-148; D=-22;
/I:         I=-22; DM=-55;
/M: SY='V';  M=  24,-150,   6,-143,  29, -46,-146,-129, -31,  -2,  22, -17, -24,  -6,-147,  26, -18,  38,-153,  -2; D=-22;
/I:         I=-22; DM=-55;
/M: SY='H';  M= -31,-151,-150,-146,  11,-155,  65,  38,-140,   5,  36,-143,-153,  -6,  13, -34, -33,  37,-142,  63;
/M: SY='S';  M= -42,-144, -42,  -4,-149, -61,-136,-146, -14, -38,-142,  46,-142,-128,  15,  74,  68,-140,-161,-144;
/M: SY='R';  M=-138,-156, -22,  71,-154,-150,-134,-151,   3, -44,-143,-133,  34,-121,  75,   8,   8, -38,-157,-145;
/M: SY='E';  M=  26,-152,  48,  81,-156, -39,-135, -22, -15, -51,-145, -29,-140,  -3, -29,  19,-133,-144,-159,-147;
/M: SY='E';  M=-139,-159,  42,  94,-161, -24,-132,-161,  30,-155,-149,-129, -16,  26,  17,-134,-138,-155,-158,-148;
/M: SY='L';  M=-142,-148,-159,-152,-123,-163,-149,  49,   4,  81,  -2,-155,-157,-146,-147,-151,-138,  10,-150,-133;
/M: SY='R';  M=-140,-153, -25, -24, -26,-151,-135,-136,  48,  10,  17,-136,  14,  -4,  62,  -2, -17,   3,-146,  36;
/M: SY='E';  M=  18,  16, -22,  59,   2,-146,  11, -22, -25, -25,  51,-135,-143, -10,-137,  21,  27, -17,-153, -14;
/I:         I=-42; MD=-106;
/M: SY='M';  M= -41,-148, -20,-152,  14,-160,-146,  25,-152,  63,  91,-153,-156,-147,-151,-149, -35,  12,-150,-130; D=-42;
/I:         I=-42; MI=-106; MD=-106; IM=-106; DM=-106;
/M: SY='V';  M= -10,-148,-160,-152, -14,-160,-153,  38,-150,  54,-116,-155,-157, -13, -22,-147,-136,  66,-154,-135; D=-42;
/I:         I=-42; DM=-106;
/M: SY='R';  M= -16,-153,  45,  37,-150,-144,  29, -35,  18,-150,-144, -41,-143,-124,  58,  32,  26,-146,  38, -32;
/M: SY='E';  M=  13,-151,  24,  72, -23,  -2,-138, -21,-134,  23,  33,-136,-144, -16,-140,   4,-135, -16,-155,-141;
/M: SY='H';  M=  24,-148,   8, -31,-149,  36,  81,  11,-138,-144,  13, -24,-144,-133,-142,  59,  -4,-139,-160,-138;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='Y';  M=  34,-152,  31,  35, -15,  16,   9,-140,-139,   2,  22,-136,-148,   1,-142,  -9, -45, -31,-148,  45; D=-33;
/I:         I=-33; DM=-84;
/M: SY='Q';  M=-136,-155, -42,  46,-155, -24,-134,-151,  59, -17,-141, -11,  39,  65, -17,  18, -24,-149,-154,-145;
/I:         I=-38; MD=-97;
/M: SY='N';  M=  10,-151,   5,  39,-143,   8,  12, -16, -48,-148,-143,  52,-146,-130, -15,  36, -18, -51,-151,  49; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='G';  M=-131,-154,  17,  38,-160,  85,-143, -48, -26,-160,-152,  -7,-144,-135,-145,  17, -40,-156,-157,-153; D=-38;
/I:         I=-38; DM=-97;
/M: SY='E';  M=   5,-152,  44,  52,-147, -73,-140, -45,  -5,  -7,  -2, -10, -32, -30,  15,-136, -25,  40,-161,-145; D=-38;
/I:         I=-38; DM=-97;
/M: SY='I';  M= -43,  -1,-155, -22,  24, -55,-149,  59,-145,  55,-118, -32,-156,-146,  18,-147, -25, -10,-150,-132;
/M: SY='D';  M=  -8,-150,  53,  27,-155, -53,-137,-146,  -1,-151,-146,  52, -13,-130,   0,  11,  48,  -1,-166,-148;
/M: SY='Q';  M= -31,-157,   8,  16,-157, -48,  73, -42,  60,-151,-141, -36,   5,  73, -56,-132,  14,-151,-159,-140;
/M: SY='E';  M= -13,-154,  64,  66,-157,   9,  -9, -25,-131, -46,-147, -35,-143,  18,-138,  41,-133,-148,-162,-147;
/M: SY='E';  M=-140,-156,  31,  94,-151,-153,-135,-144, -30,   5,  28, -18, -31,  -2,-134,-137, -19, -26,-160,-147;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_09 which contains 561'176 sequence entries.


Total number of hits 49 in 49 different sequences
Number of true positive hits 49 in 49 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] CNNM transmembrane
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
49 sequences

CNNM1_CAEEL (A3QM97    ), CNNM1_HUMAN (Q9NRU3    ), CNNM1_MOUSE (Q0GA42    ), 
CNNM2_CAEEL (Q9GYL2    ), CNNM2_HUMAN (Q9H8M5    ), CNNM2_MOUSE (Q3TWN3    ), 
CNNM2_RAT   (Q5U2P1    ), CNNM3_CAEEL (A0A131MCZ8), CNNM3_HUMAN (Q8NE01    ), 
CNNM3_MOUSE (Q32NY4    ), CNNM4_CAEEL (Q17586    ), CNNM4_HUMAN (Q6P4Q7    ), 
CNNM4_MOUSE (Q69ZF7    ), CNNM4_RAT   (P0C588    ), CNNM4_XENTR (A0JPA0    ), 
CNNM5_CAEEL (G5ED05    ), MAM3_YEAST  (Q12296    ), Y107_HAEIN  (Q57017    ), 
Y1254_SYNY3 (P74078    ), Y1327_ARATH (Q9ZVS8    ), Y146_MYCGE  (Q49399    ), 
Y1559_ARATH (Q84R21    ), Y159_MYCPN  (P75586    ), Y1733_ARATH (Q8RY60    ), 
Y1841_MYCTO (P9WLQ6    ), Y1841_MYCTU (P9WLQ7    ), Y1842_MYCTO (P9WFP2    ), 
Y1842_MYCTU (P9WFP3    ), Y2366_MYCTO (P9WFP0    ), Y2366_MYCTU (P9WFP1    ), 
Y2387_MYCBO (P67131    ), Y2452_ARATH (Q9ZQR4    ), Y260_SYNY3  (P74409    ), 
Y3307_ARATH (Q9LK65    ), Y4370_ARATH (Q8VZI2    ), Y4423_ARATH (Q4V3C7    ), 
Y4424_ARATH (Q67XQ0    ), Y452_HAEIN  (P44717    ), Y5279_ARATH (Q9LTD8    ), 
YFJD_ECOLI  (P37908    ), YHDP_BACSU  (O07585    ), YHDT_BACSU  (O07589    ), 
YJ23_SCHPO  (Q9USJ3    ), YQHB_BACSU  (P54505    ), YRKA_BACSU  (P54428    ), 
YTFL_ECO57  (P0AE47    ), YTFL_ECOL6  (P0AE46    ), YTFL_ECOLI  (P0AE45    ), 
YUGS_BACSU  (O05241    )
» more


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission