PROSITE entry PS51860
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General information about the entry
| Entry name [info] | REM_1 |
| Accession [info] | PS51860 |
| Entry type [info] | MATRIX |
| Date [info] |
25-APR-2018 CREATED;
25-APR-2018 DATA UPDATE; 13-SEP-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51860 |
| Associated ProRule [info] | PRU01207 |
Name and characterization of the entry
| Description [info] | REM-1 domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=78; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=78; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1723568; R2=0.0081206; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1272; N_SCORE=12.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=657; N_SCORE=7.5; MODE=1; TEXT='R?'; /DEFAULT: M0=-49; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='N'; M= 14,-124, 35, -55,-129, -62, 40, -17, 22,-126,-119, 45, -11,-106,-110, 37, 18,-118,-139,-119; /M: SY='L'; M= -53,-125, -73, -37, 12, -64, -28,-102, 1, 45, 40, -53, 29,-114,-117, 14, 3, -62,-119, 32; /M: SY='P'; M= -23,-132, 50, 32, -25, -43,-114, -22,-105, -39,-117, -52, 61, -22, 31, -23, -55, -27,-134,-120; /M: SY='P'; M= 17, 15,-114, -53, -30, -15,-116,-122, 42,-123, 7, -38, 53, 31, -48, -3, 28, -62,-130,-120; /M: SY='P'; M= -59,-134,-106, 45,-133, -24, 6,-127, 1, -31,-117,-110, 72, 69,-107, 14,-111,-127,-131,-122; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='Q'; M= -48, -23,-115, -39,-120, -47, -10, -28, -19, -13, -14, -44, 21, 51, 41, 17, 28, -25, 1, -22; /M: SY='R'; M= -39, 1, -36, 21,-121, -5,-114, -40,-101, 8, -25,-112, -9, 32, 55, 11, -19, -7,-131,-118; /M: SY='R'; M= 5, -13, -35, 2, -54, -12,-110, -19, 24, -20, 40,-107, -11, 41, 49, 14, -48,-113,-126,-114; /M: SY='M'; M= -6,-120, -38, -39, -32, 3,-107, -56, 24, -55, 71, -34, 20, 43, -14, 53, -12, -50, -6,-110; /M: SY='K'; M= -8, -3, -38,-102, -4, -51,-106,-110, 53, 22, -13, 28, -4, 23, 32, 8, 8,-110,-122,-108; /M: SY='L'; M= -58,-121, -25, -14, -7, -56,-115, 43,-114, 62, -88, 15, 34,-112, -4, -56,-107, -15,-121,-105; /M: SY='Q'; M= -6,-125, 41, 44,-126,-113,-101,-120, 3, -16,-110, -21, -26, 91, -7, 13, -49,-118,-126,-113; /M: SY='Q'; M=-108,-124, 25, 27, -19, -44, 49,-115, -20, 13,-106, 26, 12, 63, -2, 22, -36,-116,-125, -25; /M: SY='R'; M= -14,-123, -33, 22,-115,-120, 4, -27, 52, 3, 54, -49,-116, 39, 56,-106, -39, -22,-124,-109; /M: SY='I'; M= -52,-121, 29, -47,-103, -72,-115, 55, -1, 45, -17, -9,-122,-109, 26, -55,-106, 21,-125,-107; /M: SY='E'; M= 38, 46, 30, 54,-124, -63, -14,-120, -68, -50, -17, 12,-113, 50, -18, -3, 3,-114, -1,-115; /M: SY='E'; M= 11,-124, 52, 64,-123, -42, -8, -47, -95, -58, -29, 20,-113, 37, 27, -2,-104, -42,-128, -29; /M: SY='L'; M= -55,-119,-130,-124, -90,-132,-116, 56,-122, 74, 19,-126,-128,-117, -36,-121,-108, 1,-115, 30; /M: SY='Q'; M=-108,-126, -97, 42,-123,-115, 18,-123, 23,-120,-110, 41,-114, 87, 48, -2, -37, -53,-123, 2; /M: SY='R'; M=-112,-127,-105, 9, 25, -50, 56,-124, 61,-117, -10,-101,-117, 41, 79,-106,-110,-121,-120,-102; /M: SY='K'; M= -45,-127, 10, 42,-128, -70, 39,-128, 83,-123,-113, -96,-111, 69, 2,-102,-107,-124,-124,-111; /M: SY='I'; M= -8,-120,-130,-125, 6,-131,-121, 78, -38, 59, -3,-124,-125,-119,-122,-119,-107, -19,-117, -38; /M: SY='Q'; M= -25,-126, 59, 63,-127,-116, -2, -62, -59, -33,-113, -22,-113, 68, 40, 1,-106,-120,-129,-113; /M: SY='K'; M=-109,-123,-114,-103, -4,-124, 39, 35, 71, -42, -99,-106,-118, 20, 39,-110,-106, 42,-122,-104; /M: SY='E'; M= 23,-125, -82, 113,-130,-119,-103,-129, -91,-123,-118,-105,-104, -34,-101,-102,-107,-120,-127,-121; /M: SY='M'; M= -4, -6,-111, 13, -22,-119, 2, 25, 23, 30, 61, 9,-118, -23, -12, 7, -12, -32,-123,-106; /M: SY='K'; M= 31,-123, 41, -16,-128,-112,-103,-125, 60,-123,-113, -33,-114, 58, 58, -20,-105,-119,-125,-114; /M: SY='M'; M=-108, -7, 0,-111,-100, -48,-110, 26, 6, 9, 82,-113,-121, 42,-109, -37,-105, 47,-118, 38; /M: SY='R'; M= 2,-124,-111,-100,-117,-120,-108, 34, 67, -52,-104,-104,-117, -4, 79, -23,-106, -29,-122,-110; /M: SY='E'; M= -10,-124, 42, 77,-127,-116, -11,-124, -18, -63,-114, 11,-110, 46, 21, -41, 18, -75,-130,-115; /M: SY='G'; M= 40,-120,-110,-118,-128, 95,-115,-131,-114,-129,-119, 21,-116,-111,-121, -95,-110,-122,-123,-124; /M: SY='A'; M= 80,-113,-120,-115, -31,-109,-119, 40,-115, 22, -26, -9,-119,-112,-118,-100,-102, 3,-122,-110; /M: SY='E'; M=-107, 32, -90, 88,-121, -55,-104,-124, 38, -62,-116, 29,-109, -25, -97, -2, 13,-119, 33, -18; /M: SY='N'; M= 5,-119, -14, -97,-125,-106, -99,-124, 73,-126,-115, 96,-116, -35, 7, -42, -34,-121,-130,-116; /M: SY='M'; M=-110,-117, -16, -19, -97,-127,-109, -36, -34, 54, 119,-119,-122,-109,-114,-118,-107, 21,-123,-101; /M: SY='R'; M= -64,-121,-119,-109,-103,-125,-111, 21, 36, 37, 47,-113,-121, 9, 47, -49, -20, 31,-121, -14; /M: SY='Q'; M= -3,-124, 29, -48,-126,-112, 24,-123, 50,-122,-112, -7,-115, 70, 55, 29,-103, -46,-126,-111; /M: SY='V'; M= 42,-113,-117,-112,-106,-114,-116, -89, -49, 38, 15, -29,-119, 0,-114, 21, 32, 47,-126,-109; /M: SY='Y'; M= -9, 38,-116,-116, -27,-119,-102,-100,-113, 32, -96,-111,-122,-111,-115, 6, 63,-101,-101, 96; /M: SY='S'; M= -9,-117, -10, 13,-120, 0,-105,-118, 22, -35,-112, 24,-112, 31, -29, 59, 45,-113,-126, -18; /M: SY='N'; M= -50,-119, 49, -32,-123, -53,-100, -26, 40,-119, 25, 80,-115, 24, -48, 25, 10,-116,-133,-114; /I: I=-25; MD=-63; /M: SY='N'; M= -29,-147, -16, -6,-152, 26, -24,-151,-130, -61,-143, 50,-143, -52, -69, -36, -21,-148,-159,-145; D=-25; /I: I=-25; MD=-63; /M: SY='P'; M= -70, -20,-139,-135, -37, -2, -29,-152, 1,-154,-145, -48, 54,-134, -42, 13, -27,-149,-154,-145; D=-25; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='D'; M=-134,-152, 74, 1,-158,-137,-122,-152, -14,-148,-141,-112,-135, 69,-120,-123,-129,-150,-156,-137; D=-25; /I: I=-25; DM=-63; /M: SY='R'; M= -29,-124,-108, 0,-117, -47, 5,-112, 41, 0, 57, -2, 23, 27, 68, -42, -50, -54,-124,-110; /M: SY='K'; M= -28,-125, -19, 50,-124, 27,-106,-124, 76, -63, 14,-100,-112, -25, 27, -47, -40,-120, 0,-114; /M: SY='D'; M= 8,-118, 56,-100,-114,-112, -2, -45,-107, 11,-102, 16,-118, 43,-111, 44, -99, 44,-132,-111; /M: SY='L'; M= -25,-122,-117,-107,-107,-122, 31, -8, 22, 52, -93,-113, 48, 17, 35, -23,-107, 4,-124,-107; /M: SY='S'; M= 41,-117,-106, 12,-118, 4,-108,-113, 29, 15,-106, -34,-114, 39, -13, 49, -35,-109,-124,-113; /M: SY='D'; M= 8,-122, 47, 41,-124,-112, 31,-124, 36,-122,-114, -26, -1, 29, 2, 25, 13,-118,-127, -16; /M: SY='A'; M= 70, 52,-122,-115,-108,-112,-120, -92,-114, 27, -26,-117,-122,-113, -18,-102, -27, 48, 17,-111; /M: SY='Q'; M= 11,-122, 44, 39,-124, -68, 35, -44, -38, -63,-109, 8,-113, 73, -27, -1, 13, -5,-130,-112; /M: SY='Q'; M= 28,-121, -34, -6,-121, 0, -17, -44, 18, 2,-105, -23, 18, 74, -32, 9, 5, -59,-124,-113; /M: SY='N'; M=-107,-122,-101, 21,-116, -30,-102, -55, 40, 11, 52, 55, -26, 52, 18, 8, -56, -75,-125,-111; /M: SY='L'; M= -55,-118,-128,-121, -20,-128,-114, 39,-117, 74, 52,-122,-126,-113, 2, 5,-107, -51,-118, -35; /M: SY='Q'; M= 21,-120, 1, -15,-118, -54,-106, -3, 16, -23, 40, -4,-116, 59, 38, 16, -11, -16,-125,-111; /M: SY='E'; M= -64,-124, 49, 81, -5, -47,-105, -24, -19, -36,-110,-102,-111, 6,-105, -6, -33, 13,-124, 2; /M: SY='S'; M= -14, 62,-108,-111,-114, 9,-110, -63,-109, -84,-111, 15,-116,-105,-114, 85, 10, 11,-127, 11; /M: SY='N'; M= -9,-118, -38, -42,-123, -29,-101,-120, 47, -57, -18, 82,-115, 12, 22, 36, 6,-117,-129,-115; /M: SY='Q'; M= 4,-121,-103, 9,-120, -69, -1,-117, 21, -8,-107, 3,-114, 77, 32, 41, 6,-114,-123, -26; /M: SY='K'; M=-110,-123, -10, -31,-125,-112,-100,-125, 86,-125, -10, 74,-115, -90, 52, -44,-103,-123,-127,-114; /M: SY='I'; M=-112,-121,-133,-128, -93,-136,-125, 86,-126, 61, -11,-127,-126,-121,-126,-122,-107, 13,-121,-103; /M: SY='D'; M= -2,-124, 68, 59,-126, -40,-102, -48, -15, -32, -25, 10,-112, 68,-101, -61, -19, -66,-130,-115; /M: SY='L'; M= -2,-121,-115, -1, 14,-122,-105, -33, -3, 51, 22, -29,-122, 39, 19, -27,-108, -39,-111, 48; /M: SY='L'; M=-115,-119,-130,-124, 9,-133,-111, 2,-124, 88, -79,-129,-131,-118,-121,-123,-111, -88,-108, 53; /M: SY='R'; M=-109,-125,-101, 35,-123,-119, 42,-120, 56,-116, 38, -32,-114, 53, 67, -35, -2, -48,-125,-109; /M: SY='M'; M= 4,-121, -40, 54, -52, -2, -5,-110, 14, -12, 70, -22,-114, 30, -10, 14,-105, -47,-121, 6; /M: SY='Q'; M= 14,-123, -28, 67,-128,-112, -33,-125, 27,-122,-114, 8,-110, 71, 0, 30, -35,-119,-126,-115; /M: SY='L'; M= -30,-117,-129,-123, -93,-129,-118, 47,-123, 80, 18,-125,-127,-117,-122, -9, -62, -25,-120,-103; /M: SY='Q'; M= -63,-127, 12, 56,-120,-118, 39, -55, 30, -38,-109, -4,-114, 74, 39, -29,-107,-120,-122, 16; /M: SY='K'; M= -53,-125, -9, 54,-126, -27,-103,-126, 72, -55,-114, -24,-112, 28, 49, 5,-105,-121,-124,-114; /M: SY='L'; M= 14,-119,-121,-115, 22,-122,-107, -40,-108, 62, -90, -17,-126, -22, 37, -50, -36, -52,-108, 60; /M: SY='N'; M=-107,-121, -34, 50,-119,-114, 35,-114, 36, 5, -8, 57,-114, 46, -20, 14, -8, -42,-128,-111; /M: SY='A'; M= 39,-119, 12, 37,-118, 18,-109, 2, -47, 2, -15, -18,-114, 32, -36, 23, -26, -49,-126,-114; /M: SY='W'; M= -13,-123,-108, 39, -7, -71, 40, -46, -46, 23, -30, -39,-117, 36, 24, 18, -15, -22, 85,-101; /M: SY='L'; M=-108, -47,-116,-112,-102, -31, 44, 10, -19, 54, -7, 15,-123, 15, 11, 3, -42, 22,-123, -17; /M: SY='A'; M= 36,-120, 13, 13,-117, -7,-112, -1,-104, -21, -13, -4, 34, 9, 12, -3, -38, 28,-127,-115; /M: SY='E'; M= -17,-121, 31, 46, -30, -13,-109, -56, -28, 12, -6, 4, 25, -5, -23, -44, 30, 10,-127,-112; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 98 in 67 different sequences |
| Number of true positive hits | 98 in 67 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Feature key [info] | DOMAIN |
| Feature description [info] | REM-1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
67 sequences
CIP4_DANRE (Q5U3Q6), CIP4_HUMAN (Q15642), CIP4_MOUSE (Q8CJ53), CIP4_PONAB (Q5RCJ1), CIP4_RAT(P97531), FBP1L_HUMAN (Q5T0N5), FBP1L_MOUSE (Q8K012), FBP1L_RAT (Q2HWF0), FBP1L_XENLA (Q6DCZ7), FBP1L_XENTR (Q6GUF4), FNBP1_HUMAN (Q96RU3), FNBP1_MOUSE (Q80TY0), FNBP1_RAT (Q8R511), FNBP1_XENLA (Q6GNV5), KPC1_ASPNG (Q00078), KPC1_CANAX (P43057), KPC1_COCHE (O42632), KPC1_HYPJE (Q99014), KPC1_NEUCR (P87253), KPC1_YEAST (P24583), NOSTN_BOVIN (Q2KJB5), NOSTN_HUMAN (Q8IVI9), NOSTN_MOUSE (Q6WKZ7), NOSTN_RAT (Q5I0D6), PCK1_SCHPO (P36582), PCK2_SCHPO (P36583), PKCA_ASPFU (Q4WVG0), PKN1_BOVIN (A1A4I4), PKN1_HUMAN (Q16512), PKN1_MOUSE (P70268), PKN1_RAT(Q63433), PKN2_DANRE (A7MBL8), PKN2_HUMAN (Q16513), PKN2_MOUSE (Q8BWW9), PKN2_RAT(O08874), PKN3_HUMAN (Q6P5Z2), PKN3_MOUSE (Q8K045), PKN_DROME (A1Z7T0), RHN2A_XENLA (Q6DJJ6), RHN2B_XENLA (Q63ZR5), RHPN1_HUMAN (Q8TCX5), RHPN1_MOUSE (Q61085), RHPN2_BOVIN (A4FUC9), RHPN2_CANLF (Q8HXG3), RHPN2_DANRE (Q6TNR1), RHPN2_HUMAN (Q8IUC4), RHPN2_MOUSE (Q8BWR8), RICTR_SCHPO (Q09743), ROCK1_HUMAN (Q13464), ROCK1_MOUSE (P70335), ROCK1_PANTR (P61584), ROCK1_RABIT (O77819), ROCK1_RAT (Q63644), ROCK2_BOVIN (Q28021), ROCK2_HUMAN (O75116), ROCK2_MOUSE (P70336), ROCK2_PIG (M3TYT0), ROCK2_RAT (Q62868), RTKN2_DANRE (Q5XIZ9), RTKN2_HUMAN (Q8IZC4), RTKN2_MOUSE (Q14B46), RTKN2_XENLA (Q5XGX5), RTKN_HUMAN (Q9BST9), RTKN_MOUSE (Q8C6B2), RTKN_RAT(Q6V7V2), TOCA1_CAEEL (Q19253), TOCA2_CAEEL (Q9XUS7)» more
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| PDB [Detailed view] |
7 PDB
1CXZ; 1URF; 2KE4; 2RMK; 3O0Z; 4NKG; 5FRG |