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PROSITE entry PS51866


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General information about the entry

Entry name [info] MOP
Accession [info] PS51866
Entry type [info] MATRIX
Date [info] 12-SEP-2018 CREATED;
12-SEP-2018 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51866
Associated ProRule [info] PRU01213

Name and characterization of the entry

Description [info] Mop domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=68;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=63;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6477885; R2=0.0085225; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1157; N_SCORE=12.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=453; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-31; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Q';  M=  16, -75,  20, -15, -55,  10,  46, -72,  33, -11, -17, -15, -68,  51,  24,   4, -58, -69, -78, -62;
/M: SY='T';  M=  -8, -66, -63, -63, -64,  -2, -67,  21, -62,   5, -54, -53, -66,  -2, -67,  52,  69, -18, -80, -64;
/M: SY='S';  M= -20, -64, -54, -57, -74, -50, -58, -73, -56, -77, -70,  29, -64, -49, -61, 100,  11, -65, -84, -67;
/M: SY='I';  M=  59, -70, -74, -68, -61, -67, -75,  75, -68, -34, -46, -36, -15,  13, -72, -56, -55,   0, -75, -63;
/M: SY='R';  M= -66, -17,   7, -56, -63, -77, -15, -61, -39,  39, -51, -61,   8, -21,  90, -37, -44, -62, -77, -61;
/M: SY='N';  M= -62, -67, -35, -57, -77, -50, -43, -76, -48, -84, -70, 125, -73, -50, -56, -44, -47, -78, -96, -72;
/M: SY='Q';  M=   1,   4, -69, -34, -63, -75, -66,  56, -28, -15, -47, -64, -72,  76,   7, -59, -26,  34, -76, -61;
/M: SY='L';  M= -68, -70, -86, -78,  52, -85, -70,  -8, -78,  77, -34, -82, -84, -74, -75, -76, -64,  -4,  44, -44;
/M: SY='P';  M=   6, -80, -61,   8,   8, -30, -25, -73,  13, -57, -66, -24,  89, -55,  37, -17, -33, -71,  14, -65;
/M: SY='G';  M=  51,  10, -69, -71, -72,  69, -73, -58, -69, -36, -61, -59, -70, -67, -74, -50, -59,  35, -77, -72;
/M: SY='T';  M= -59, -72, -58,  -5, -69, -71, -17,   8,  49, -63, -58,  10, -67, -23,  51, -20,  56,  10, -80, -64;
/M: SY='V';  M= -57, -70, -84, -80, -52, -86, -85,  71, -76, -28,  -9, -77, -77, -76, -78, -69, -54,  82, -81, -59;
/M: SY='V';  M=  22, -69,  -9,   7, -63, -70, -24,  22,  15,  -8, -38, -60, -68, -58, -26,   5,  34,  40,   9, -62;
/I:         I=-38; MD=-97;
/M: SY='S';  M=  27, -72,  25,  32, -80,  28,  12, -78, -37, -77, -69, -10, -65,  23,   4,  45, -23, -71, -81, -69; D=-38;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='I';  M= -35,  -1, -78, -30, -53, -82, -25,  68, -67,  32,   7, -72, -76, -12,   5, -18, -35,  26,   3, -58; D=-38;
/I:         I=-38; DM=-97;
/M: SY='E';  M=  -2, -40,  24,  57, -42, -42,   8, -26, -12, -54, -64,  25, -37, -12,   1,  26, -17, -12, -77,  16;
/M: SY='P';  M= -10, -21,  41,  43, -75, -69,  32,  -4,  -3, -39, -63, -25,  60, -52,  10, -23,  -5, -19, -83, -67;
/I:         I=-24; MD=-60;
/M: SY='G';  M=   5, -86,  35, -26, -48,  48, -11, -23, -47, -60, -77, -61, -79,   8,  -2, -24, -39, -52, -89, -78; D=-24;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='D';  M=  15, -82,  53, -27, -86,   5, -69, -78, -13, -44, -75,   4,  38, -16, -36, -21,  -5, -26, -92, -79; D=-24;
/I:         I=-24; DM=-60;
/M: SY='V';  M= -61, -77,  28,  40, -74, -26,  -3, -41, -59, -27, -63,  33,  18,  -9, -37,   0, -22,  41, -89, -71; D=-24;
/I:         I=-24; DM=-60;
/M: SY='N';  M= -23, -75,  33,  13, -79,  20,   5, -77, -31, -68, -68,  39,  32,  35,  14,  23,  15, -73, -83, -69;
/M: SY='A';  M=  38,  36, -34,  12, -30,  26, -64, -24, -37, -66, -62,  -8,   4,  17, -39,  13, -14,  11, -75,  -1;
/M: SY='H';  M=   5, -19,  10,  46, -68, -70,  60, -36, -37,  15,  11, -31, -67,  55, -20, -21, -11, -18, -81, -59;
/M: SY='V';  M= -21, -68, -83, -77, -53, -83, -83,  38, -75,  -4, -11, -78, -78, -76, -77, -67, -52,  91, -84, -60;
/M: SY='L';  M= -11, -72,  24,  21, -29, -73, -14,  -9,  -5,  30,  10, -33, -70,   3,  18, -12,  17,  15, -79, -60;
/M: SY='V';  M= -58, -70, -80, -72, -52, -36, -74,  28, -71,  38,  28, -75, -78,  20, -43, -68, -56,  73, -79, -58;
/M: SY='R';  M=  16, -73,  15,   3,   5, -37,   3, -35,  31,   2, -57,   1, -69,   5,  44, -44,  16, -29, -76, -60;
/M: SY='L';  M= -12, -70, -12, -73, -21, -82, -71,  37, -74,  72,  -6, -77, -80, -70, -43, -71, -60,   9, -73, -55;
/M: SY='D';  M=  37, -74,  50,  36, -80,  10, -60, -74, -31, -54, -68,   1,  27,  14,  -1, -34,   3, -47, -82, -71;
/I:         I=-26; MD=-67;
/M: SY='C';  M=  11,  52,  22, -24, -69,  38, -71, -12, -47,  13, -58, -30,  -5, -27, -73, -31, -29,  15, -83, -71; D=-26;
/I:         I=-26; MD=-67;
/M: SY='G';  M= -14,   2,  -8, -34, -86,  85, -75, -90, -73, -46, -78, -19, -75, -71, -80, -36, -47, -84, -83, -82; D=-26;
/I:         I=-26; MD=-67;
/M: SY='G';  M= -43,-103, -36,  -7,-108,  47, -90,-108, -10,-108, -98, -44,  25, -45, -88, -27, -86,-104,-102,-101; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Q';  M=  19,  33,  30, -19, -76, -63,  30, -20,  -3, -71, -64,  27, -14,  39,  -1,  15,  37, -64, -85, -66; D=-26;
/I:         I=-26; DM=-67;
/M: SY='T';  M= -21,  21, -28,   6, -33, -30,   1, -18,   1, -68, -62,  24,  40, -17,  30,   5,  42, -16,  -1,  -9;
/M: SY='L';  M= -66, -71, -85, -79, -18, -87, -73,  59, -78,  73,   0, -81, -80, -72, -77, -75, -61,   2, -72, -54;
/M: SY='W';  M= -13,  37, -72,  -3, -53, -44, -72, -41, -15,  40, -51, -69, -73,   3, -27, -36,  35, -35, 117, -51;
/M: SY='A';  M=  85,  -5, -68, -62,   4, -52, -69, -60, -63, -64, -60, -61, -68, -60, -67,  32, -50,   0, -75, -65;
/M: SY='R';  M= -22,  48, -63, -59,  -8, -70, -61, -18, -43, -64, -60,   8, -72, -18,  76,  21,  37,   8, -79, -62;
/M: SY='I';  M= -11, -74, -83, -78, -51, -84, -81,  90, -75,  -5,  -4, -75, -75, -12, -78, -69, -57,  42, -76, -58;
/M: SY='T';  M= -50, -63, -56, -59, -69, -64, -65, -62, -57, -66, -62,  -8,  -4, -59, -65,  40, 104, -54, -87, -66;
/M: SY='R';  M=   6, -74, -34,  -5, -68, -47, -15, -58,   4,   3, -56,   3,  30, -27,  63, -56,  22,  17, -79, -65;
/M: SY='W';  M= -30, -80,  34, -54, -35, -69,  29, -70,   7,  -7, -62,  -6, -72,  16,  48,   1, -16, -71, 111,   6;
/M: SY='S';  M=  52, -65, -57,   4, -76, -51, -61, -72, -56, -73, -67, -50, -64,  16, -61,  85, -43, -62, -79, -68;
/M: SY='A';  M=  47,  38, -71, -62,  -4, -33, -19,   0, -55,   3, -55, -65,   9,   3,  44, -13, -58,  -7,  39, -60;
/M: SY='D';  M=  17, -74,  76,  31, -78, -63,  43, -31, -14, -74, -68,  30, -65,   2, -34, -31,  12, -50, -89, -66;
/M: SY='Q';  M=  19, -77,  25,  61, -79, -67,  11, -76, -30, -44, -21, -28, -64,  62,  41, -15, -44, -71, -79, -66;
/M: SY='L';  M= -67, -70, -85, -77, -41, -85, -69, -33, -77,  88,  14, -84, -83, -70, -75, -77, -64, -41,  56, -51;
/M: SY='Q';  M=  12, -75,   4,   5, -81,  52, -15, -80,  -7, -78, -67,  42, -67,  61,   9, -12, -58, -69, -78, -69;
/I:         I=-38; MD=-97;
/M: SY='L';  M= -67, -72, -86, -80,   4, -88, -74,  42, -80,  75, -33, -83, -83, -74, -78, -77, -63,   6, -72, -53; D=-38;
/I:         I=-38; MD=-97;
/M: SY='A';  M=  37, -77, -22,  14, -41, -46,  27, -14,  29, -69, -64, -60, -71,  20,  34, -10, -61,   2, -81, -67; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='P';  M= -26, -83, -38,  23, -75, -75, -70,  10, -60, -33, -61, -69,  89,  18,  -7, -63, -15,  19, -82, -73; D=-38;
/I:         I=-38; DM=-97;
/M: SY='G';  M= -50, -77, -59,  13, -83,  98, -68, -90, -66, -85, -75, -17, -67, -62, -74, -50, -67, -83, -75, -77;
/M: SY='Q';  M= -33, -75,  10, -12, -71, -37, -57, -25,  38, -10,  43, -53, -68,  74,  13,  13, -18,  -6, -76, -62;
/M: SY='Q';  M=   6, -77,   3,  58, -78, -45, -14, -60, -30, -65, -30,  20,  10,  62,  18,  -2, -13, -72,  42, -65;
/M: SY='V';  M=   9, -67, -81, -75, -52, -79, -80,  10, -74,  25, -19, -77, -78, -73, -75, -64, -32,  84,   0, -60;
/M: SY='W';  M= -68,  -8, -77, -73,  51, -77,  33,  -1, -68,  -7,   3, -70, -78, -68, -45, -65,  27, -17, 103,  78;
/M: SY='A';  M=  89, -63, -71, -63, -19, -54, -71,   8, -65, -33, -55, -65, -69, -62, -69, -46, -53,   4, -75, -66;
/M: SY='Q';  M= -60, -77, -64, -50, -25, -72,  30,  -3, -53,  25,   4, -59, -72,  97, -21,   1, -59,   8, -71,   2;
/M: SY='I';  M= -63, -73, -86, -82,  51, -87, -81,  83, -78,  -9, -39, -77, -77, -78, -79, -72, -58,  48, -68, -48;
/M: SY='K';  M= -63, -76,   6, -41, -79, -68, -57, -79, 104, -79, -67,  16, -64, -41, -26, -56, -56, -75, -75, -66;
/M: SY='A';  M=  64, -65, -62, -59, -76,  28, -65, -71, -60, -72, -65, -53, -65,  15, -64,  58,  14, -61, -78, -70;
/M: SY='V';  M= -37, -69,   7,  -2, -61, -72, -69, -36, -64, -34,  13, -27,  14, -11, -68,  25,   2,  75, -83, -21;
/M: SY='S';  M=  57, -67,  -9, -21, -16, -55,   5, -70, -57, -70, -65, -53, -66,  15, -19,  63,  -1, -62,  60, -60;
/M: SY='V';  M= -59, -69, -84, -78,  -5, -85, -79,  42, -76,  40,  10, -79, -79, -75, -77, -71, -56,  75, -78, -56;
/M: SY='M';  M=   7, -71,  16, -27, -59, -36,  -5,  39,  -5,  14,  68, -32, -71, -62, -66, -28,  28,  -1, -80, -60;
/M: SY='I';  M=  15, -77, -36, -26, -63,  -8, -69,  31, -43,  27, -50, -69,  -6,  29,  20, -41, -62,   8, -77, -27;
/M: SY='A';  M=  41, -85, -26, -31, -11, -18,  -1, -76, -75, -24,   0, -75, -26, -35, -12, -16, -15, -31, -90, -32;
/M: SY='T';  M=   0, -89,  28, -14, -92, -32, -80, -80, -73, -60, -23, -10,  -6, -18, -17, -67,  38, -15,-103, -87;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 99 in 90 different sequences
Number of true positive hits 99 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Mop
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
90 sequences

MODC1_AZOVI (P37732), MODC1_BRADU (Q89TQ9), MODC2_AZOVI (Q44538), 
MODC2_BRADU (Q89EW7), MODC_AGRFC  (Q8UCD5), MODC_ALBFT  (Q21UI2), 
MODC_ALCBS  (Q0VQ44), MODC_ALIF1  (Q5E0T4), MODC_AROAE  (Q5P4W2), 
MODC_BORBR  (Q7WP62), MODC_BORPA  (Q7W1F4), MODC_BORPE  (Q7VUJ5), 
MODC_BRUA2  (Q2YIN5), MODC_BRUAB  (Q579Z3), MODC_BRUME  (Q8YE15), 
MODC_BRUSU  (Q8FXI7), MODC_DECAR  (Q47CB7), MODC_ECO57  (Q8X4V7), 
MODC_ECOL5  (Q0TJT5), MODC_ECOL6  (Q8FJR4), MODC_ECOLI  (P09833), 
MODC_ECOUT  (Q1REG5), MODC_GRABC  (Q0BQ80), MODC_HAEDU  (Q7VKP7), 
MODC_HAEI8  (Q4QJQ0), MODC_HAEIN  (P45321), MODC_HAHCH  (Q2SJB5), 
MODC_MANSM  (Q65SW3), MODC_METCA  (Q608V9), MODC_MYCTO  (P9WQL2), 
MODC_MYCTU  (P9WQL3), MODC_PARM1  (Q2W1R8), MODC_PASMU  (Q9CMS0), 
MODC_PECAS  (Q6D7D0), MODC_PHOLL  (Q7N6R3), MODC_PHOPR  (Q6LHL2), 
MODC_PSE14  (Q48J29), MODC_PSEAE  (Q9I2N4), MODC_PSEF5  (Q4KB64), 
MODC_PSEPF  (Q3KC21), MODC_PSEPK  (Q88G95), MODC_PSESM  (Q881C1), 
MODC_PSEU2  (Q4ZSS5), MODC_RHIEC  (Q2K2X0), MODC_RHIJ3  (Q1MA70), 
MODC_RHILO  (Q98KI3), MODC_RHIME  (Q92LU2), MODC_RHOCA  (Q08381), 
MODC_RHOP2  (Q2J1U0), MODC_RHOPA  (Q6N0P7), MODC_RHOPB  (Q21BF6), 
MODC_RHOPS  (Q13CI6), MODC_RHORT  (Q2RWI9), MODC_SACD2  (Q21GS5), 
MODC_SALCH  (Q57RH4), MODC_SALPA  (Q5PG54), MODC_SALTI  (Q8Z8A4), 
MODC_SALTY  (Q8ZQR6), MODC_SHEON  (Q8EAN3), MODC_SHESM  (Q0HFA0), 
MODC_SHESR  (Q0HYN8), MODC_SHIBS  (Q324F4), MODC_SHIDS  (Q32IG0), 
MODC_SHIFL  (P59738), MODC_SHISS  (Q3Z445), MODC_THIDA  (Q3SJC6), 
MODC_VIBCH  (Q9KLL9), MODC_VIBPA  (Q87HN4), MODC_VIBVU  (Q8D740), 
MODC_VIBVY  (Q7ME63), MODC_YERPA  (Q1C951), MODC_YERPE  (Q8ZGX6), 
MODC_YERPN  (Q1CFP9), MODC_YERPS  (Q66D71), MODE_AZOVI  (P37733), 
MODE_ECO57  (P0A9G9), MODE_ECOLI  (P0A9G8), MODE_HAEIN  (P45324), 
MODE_HERSE  (Q9F4K4), MODE_SHIFL  (P0A9H0), MODE_YERPE  (P58497), 
MOP1_CLOPA  (P04952), MOP2_CLOPA  (P08854), MOP3_CLOPA  (P38366), 
MOPA_RHOCA  (Q08385), MOPB_RHOCA  (Q08386), MOP_HAEIN   (P45183), 
WTPC_PYRAB  (Q9V2C0), WTPC_PYRFU  (Q8U4K3), WTPC_PYRHO  (O57896)
» more

PDB
[Detailed view]
10 PDB

1B9M; 1B9N; 1GUG; 1GUN; 1GUO; 1GUS; 1GUT; 1H9R; 1H9S; 1O7L