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Entry: PS51977

General information about the entry

Entry name [info] WGR
Accession [info] PS51977
Entry type [info] MATRIX
Date [info] 29-SEP-2021 CREATED;
29-SEP-2021 DATA UPDATE;
29-SEP-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC51977
Associated ProRule [info] PRU01321

Name and characterization of the entry

Description [info] WGR domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=98;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=93;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4080639; R2=0.0084141; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1140; N_SCORE=12.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=487; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-21; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='T';  M= -38, -58,   6, -14, -47,   9, -33, -46,   8, -55, -63,  17, -18, -16,  -7,  11,  17, -19, -20, -55;
/M: SY='Y';  M=  20,   6, -61, -50, -20,   4,  35, -49, -27, -27, -20, -35, -44, -41, -37, -15, -11, -15, -12,  42;
/M: SY='H';  M= -38, -41, -29,   7, -13, -54,  83, -51,  -1, -33, -23, -38, -18,   3,   4, -19, -26, -32, -35,  -5;
/M: SY='V';  M= -39, -43, -79, -51, -52, -83, -70,  39, -82,  -5,   4, -71, -43, -61, -67, -39, -33,  67, -90, -49;
/M: SY='Y';  M= -34, -49, -73, -69,  40, -58,  11, -15, -55,  12,  21, -78, -44, -59, -57, -61, -27,  -2,  -3,  80;
/M: SY='Q';  M= -21,   0,  -9,  23, -67, -51,   0, -25,  14, -48,   2, -28, -18,  34,  -4,   3,  -2,   6, -39,  -9;
/M: SY='D';  M= -50, -58,  80,  29, -87, -36, -11, -64,  -1, -63, -45,   1, -28,   6, -23, -16, -30, -55, -95, -60;
/I:         I=-9; MD=-23;
/M: SY='G';  M= -15, -72,  17,   1, -64,  24, -37, -80,  -3, -70, -26,   5,   3,   1, -25,   0, -32, -60, -92, -33; D=-9;
/I:         I=-9; MD=-23;
/M: SY='D';  M= -25, -46,  25,  -5, -64,   0, -36, -69, -14, -68, -42,  17, -43, -22, -26,   5,  -3, -47, -35, -52; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='D';  M= -32, -26,  18,  -7, -14, -40, -19, -19, -17, -30, -35, -33, -45, -19, -37, -21,   5, -11, -62, -55; D=-9;
/I:         I=-9; DM=-23;
/M: SY='V';  M=  -8, -23, -69, -48, -32, -76, -27,  18, -40, -16, -11, -61,  12, -55, -37, -54, -14,  24, -36, -14; D=-9;
/I:         I=-9; DM=-23;
/M: SY='Y';  M= -52, -35, -50, -47,  17, -64, -24, -53, -66, -17,  14, -52, -48, -39, -47, -30, -24, -55,  69,  87; D=-9;
/I:         I=-9; DM=-23;
/M: SY='D';  M= -45, -54,  53, -26, -52, -64,   8, -61, -27, -18, -16,  29, -20,   4, -24,  23,  -2, -49, -64, -43; D=-9;
/I:         I=-9; DM=-23;
/M: SY='A';  M=  43,  42, -80, -49, -35, -66, -71,  -1, -55, -12,   1, -48, -54, -47, -67, -24,   1,  33, -33, -59; D=-9;
/I:         I=-9; DM=-23;
/M: SY='M';  M= -32, -37, -43, -31, -37, -60,  10, -25,   4, -10,  57, -18, -57, -26, -15, -16,  40,  13, -63,  23; D=-9;
/I:         I=-9; DM=-23;
/M: SY='L';  M= -59, -30, -72, -57, -12, -75, -41, -18, -47,  70,  18, -74, -63, -45, -43, -71, -17,  -4, -40, -34; D=-9;
/I:         I=-9; DM=-23;
/M: SY='N';  M= -16, -16,   2,   7, -36, -21,   5, -35, -36, -42, -29,  60, -75,  -5,  -4,  -2,  21,  -8, -88, -18; D=-9;
/I:         I=-9; DM=-23;
/M: SY='Q';  M= -34, -22, -46, -48,  -3, -56, -23, -32,  22,  13,  -4, -29, -60,  53,  44, -31, -56, -25, -48,  16; D=-9;
/I:         I=-9; DM=-23;
/M: SY='T';  M= -13,   0, -55, -30, -43, -47, -25,  21, -18, -34, -52, -32, -32, -11, -10,   6,  58,  25, -60, -51; D=-9;
/I:         I=-9; DM=-23;
/M: SY='D';  M= -51, -30,  80,   3, -30, -42, -20, -61, -19, -40, -60,  52, -59, -11, -25, -14, -44, -52, -56, -12; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='P';  M= -11, -52, -22, -39, -44, -21, -29,  34, -34,  13,  -6, -34,  45, -16, -41, -12, -19,  16, -29, -42; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='Q';  M=  12, -77,  12,   8, -58,  16,   2, -45,  -4, -38, -18, -26, -30,  30, -19,  29,  -1, -19, -50, -42; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='R';  M=  -4, -14,   3,  -1, -13,  -1,  16, -42,  20, -48, -32,  25, -34,  11,  26,   4,  20, -41, -12,   8;
/M: SY='N';  M= -40, -47, -12, -30, -64,  36, -16, -72,  12, -63, -69,  92, -61, -29,  -9, -14, -10, -45, -86, -52;
/M: SY='M';  M= -14, -21, -30, -24, -32, -53, -12, -14,  17, -24,  56,  47, -43,  -5,   1,  40,   6, -20, -80, -39;
/M: SY='N';  M=  -1, -34,  18, -25, -51, -38,  32, -59, -14, -65, -59,  94, -60, -14,  -1, -10, -36, -61,   3,   8;
/M: SY='K';  M= -30, -58, -22,   2, -44, -48, -30, -44,  72, -70, -25,  -5, -60, -18,  45,  28, -35, -42, -50, -24;
/M: SY='F';  M= -55, -42, -69, -70,  98, -81, -58, -32, -27, -29, -42, -50, -67, -64, -14, -56, -66, -30,  -9,  78;
/M: SY='Y';  M= -61,  -7, -65, -68,  16, -73,   2, -44, -46, -44, -41, -56, -72, -33, -41, -54, -49, -43,  86, 117;
/M: SY='K';  M= -13, -36, -34,   8, -38, -48,   6,  25,  38, -11, -28, -10, -58,  15,  37, -12,  -7,   1, -77, -29;
/M: SY='M';  M= -34, -72, -65, -67, -34, -53, -57,  56, -43,  51,  67, -47, -54, -38, -58, -65, -38,  14, -58, -46;
/M: SY='Q';  M= -27, -64, -11,  26, -81, -44, -32, -51,  -3, -58, -24, -51, -44, 103, -16,  10,   6, -63, -23, -35;
/M: SY='L';  M= -30, -31, -68, -70, -30, -59, -29,  49, -75,  54, -19, -60, -79, -26, -64, -63, -33,  46, -56, -28;
/M: SY='L';  M= -33, -44, -35,   1,  -9, -54,  -3,  27, -30,  50, -14, -28, -56,  17, -31, -19, -17,   8, -33,   4;
/M: SY='E';  M= -17, -32, -13,  52, -37,   4,  13, -38,  24, -37, -44, -41,  29,  40,   0, -24, -32, -14, -58, -22;
/M: SY='D';  M= -20, -29,  52,  -8, -58, -16,  35, -51, -13, -40, -43,  29, -18, -19, -13,  36,  28, -23, -27, -15;
/M: SY='D';  M= -29, -62,  58,   5, -49,  -7,  -5, -38,  15,  18, -53,  26,  -2, -27, -20,  -4,   2, -35, -82, -40;
/I:         I=-12; MD=-29;
/M: SY='F';  M=  -8, -33,  20, -24,  39,  -7, -42, -44,   5, -45, -48,   7, -31, -19, -41,   3,  -3, -21, -52, -59; D=-12;
/I:         I=-12; MD=-29;
/M: SY='G';  M= -23, -52, -25, -14, -71,   8, -41, -70,   3, -60, -55,  -4, -39, -17, -21,  -7, -11, -59,-103, -71; D=-12;
/I:         I=-12; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='G';  M= -55, -86,  12,  -7, -69,  39,  20, -70,   3, -77, -80,  28, -18, -32, -13,   4, -22, -66, -92, -44; D=-12;
/I:         I=-12; DM=-29;
/M: SY='T';  M= -28, -24,   4,   9, -43, -13,  -9, -37,  12, -18, -24,   6, -31,   8,   9,  -1,  24, -39, -64, -63; D=-12;
/I:         I=-12; DM=-29;
/M: SY='Y';  M= -33,   8, -82, -81,  47, -84,  12, -24, -76, -32, -43, -53, -69, -52, -75, -51, -36,  -7,  65,  91; D=-12;
/I:         I=-12; DM=-29;
/M: SY='W';  M=   3,  31, -63, -55,  -8, -53,  18,   9, -36, -33,   5, -39, -80, -34, -23,  13, -13,   3,  69,  45; D=-12;
/I:         I=-12; DM=-29;
/M: SY='V';  M= -35,  10, -73, -69,  13, -81, -49,   9, -55,  51,  -1, -58, -79, -53, -73, -47,  11,  55, -74, -22;
/M: SY='W';  M= -31, -38, -68, -39,  69, -74,   2,  -8, -46, -12, -17, -28, -65, -35, -30, -47,  16,  13,  98,  43;
/M: SY='R';  M= -26,   7, -55, -50,   2, -63, -23, -16, -15, -29,  -4,  -1, -71, -14,  60,  -6,  55,  14, -35, -15;
/M: SY='R';  M=  -9, -11, -42,   5, -55, -63,  32, -48,  24, -64, -45,  21, -70,   6,  76,  14,  -8, -45, -80, -55;
/M: SY='W';  M= -74, -69, -90, -51,  11, -75, -63, -62, -39, -61, -48, -69, -79, -60, -53, -51, -54, -79, 164,  60;
/M: SY='G';  M= -36, -76, -64, -68, -74,  98, -70, -87, -68, -70, -42, -43, -68, -66, -57, -10, -32, -73, -74, -64;
/M: SY='R';  M= -57, -63, -38, -43, -64, -47, -18, -73,  17, -59, -40, -41, -41, -26, 107, -45, -58, -63, -76, -63;
/M: SY='V';  M= -35, -55, -71, -73, -38, -68, -50,  65, -72,  -7, -32, -38, -38, -66, -49, -28,  17,  65, -44, -46;
/M: SY='G';  M= -47, -77, -32, -55, -74,  98, -55, -88, -48, -67, -47, -17, -69, -66, -66, -23, -64, -71, -53, -76;
/M: SY='T';  M=  -7, -31,  24,  28, -49, -28, -19, -44,  -4, -36, -20, -19, -59,  -4, -17,  13,  67, -18, -38, -20;
/M: SY='S';  M=  -1, -53,  14,   4, -46, -19,  -1, -29,  23, -32, -27,  13,   7,  -6,  21,  26,  20, -12, -47, -45;
/M: SY='G';  M= -22, -32, -25, -37, -70,  79, -48,   5, -32, -35, -49, -17, -18, -11, -19, -32, -17, -21, -38, -49;
/M: SY='Q';  M= -22, -64, -44, -18, -49,  30, -21, -31,  11, -54, -24, -18, -15,  85,  22,  -7, -10, -35, -75, -32;
/I:         I=-10; MD=-26;
/M: SY='G';  M= -32, -50, -23, -18, -76,  14, -19, -75, -54, -73, -68,  -1, -52,   4, -46,  -8, -36, -66, -31, -47; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='S';  M= -32,  -7, -25,   5,  -3, -25,  14, -18,  12, -22,  -4,  12, -51,  21,  13,  26,  25, -17,  -8,  11; D=-10;
/I:         I=-10; DM=-26;
/M: SY='Q';  M= -30, -27, -27, -13, -52, -55, -20, -21,  47,  13,  11,  -2, -44,  54,  35, -16,  -5, -25, -76, -45;
/M: SY='T';  M=  -4, -11, -27,   7, -15, -42,  -8,   8,   3,  14,   0, -21, -56, -13,  -1,  -7,  33,  23, -32, -13;
/M: SY='E';  M= -28, -35,  25,  34, -30,  -1,  14, -27,  31, -22, -52, -29,  21,  -1, -15,  -5,  25, -25, -79, -25;
/M: SY='P';  M= -24,   9, -12,  21,  -4,   3,  -3, -30,  -7, -18, -24, -13,  54,  11, -26,   5,  14, -32,  20,  -1;
/M: SY='F';  M= -43,  19, -18, -26,  80,  11,  20, -51, -31, -29, -17, -41,   9, -19, -45, -26, -33, -33,  -6,  50;
/M: SY='S';  M=  13, -24,  29,   9, -23,   6,  -7, -56, -24, -25,  -4,  -1,  19,  -3, -23,  37,  11, -31, -20, -23;
/M: SY='S';  M= -34, -33,  50, -16, -51, -15, -30, -59, -18, -54, -61,  38, -20, -26, -29,  57,  42, -48, -56, -63;
/M: SY='L';  M=   6, -34, -38,  27, -10, -53, -20,  -9,  16,  32, -20, -42,   7,   3,  10, -25, -37,   1,  -4, -14;
/M: SY='E';  M=  17, -57,  53,  56, -71, -15, -13, -51,  -5, -48, -46,  -4, -13,   9, -21,   7, -23, -44, -43, -26;
/M: SY='E';  M=  16, -49,  36,  49, -49, -19, -36, -50,  18, -30, -33, -10, -51,  21, -15,  12,   2, -26, -54, -48;
/M: SY='A';  M=  89,  27, -55, -58, -65, -25, -53, -39, -42, -43, -39, -55, -58, -55, -68, -24, -31, -27, -77, -71;
/M: SY='I';  M= -16, -45, -43,  13,  -5, -56, -58,  44,  23,   7,  17, -42, -64,  15,   0, -29,  -9,  23, -74, -29;
/M: SY='K';  M=  17, -29,  16,  15, -52, -38, -13, -40,  51, -43, -36,  -1, -67,  17,  25,   8,   1, -35, -20, -36;
/M: SY='E';  M=  37, -38,   0,  63, -28, -41,   2, -35,  -4, -15, -15, -18, -65,  -1,  -9, -11, -16, -35, -41, -29;
/M: SY='F';  M=  -4, -40, -72, -67, 103, -63, -59, -39, -44,   3,   2, -44, -71, -58, -54, -64, -45, -31,   2,  21;
/M: SY='E';  M=   1,  17,  16,  51, -50, -27, -26, -58,  32, -22, -11,   2, -66,  31,   9, -17, -15, -31, -80, -52;
/M: SY='K';  M=  -9, -76,   6,   9, -65, -45, -17, -71,  73, -46, -35, -11, -67,   7,  40,   3, -22, -49, -45, -59;
/M: SY='K';  M= -46, -45, -56, -52,   2, -79, -38,  26,  49,  41,   7, -40, -56,   1,  -6, -63, -28,   8,   8, -30;
/M: SY='F';  M= -29, -58, -81, -44,  94, -68, -48,  14, -41,  -4, -28, -61, -55, -57, -47, -58, -33,   3, -17,  42;
/M: SY='R';  M=   5, -52, -34,  14, -10, -31,   3, -48,  45, -10, -31,  -7, -70,  13,  51,  -9, -30, -42, -32,  -3;
/M: SY='E';  M=  13, -75,  42,  62, -63, -40, -57, -56,   3, -56, -51, -22, -64,  30, -10,  27, -21, -54, -81, -42;
/M: SY='K';  M= -48, -63, -44, -37, -51, -71, -23, -67, 100, -43, -38, -42, -52, -13,   2, -44, -46, -44, -41, -38;
/M: SY='T';  M= -35,  -5, -56, -33, -66, -61, -41, -22, -29, -12,  -5, -34, -48, -19,  11,  11,  90, -19, -84, -47;
/M: SY='G';  M= -20, -57, -35, -40, -62,  67, -25, -73,  40, -55, -51, -14, -46, -16,  38, -15, -29, -46, -76, -50;
/M: SY='N';  M= -51, -55, -26, -38, -36, -32,  -9, -29,  46, -20, -53,  83, -44, -14,  28, -29, -31, -27, -53, -46;
/M: SY='G';  M=  -6, -58,  17,  26, -61,  55,   0, -61,  -4, -44, -60,  16, -21, -13, -18,   6, -10, -30, -60, -41;
/M: SY='W';  M= -58, -42, -44, -71,  26, -67, -57, -59, -60, -52, -57, -67, -62, -69, -58, -71, -69, -57, 148,  88;
/M: SY='E';  M=  13, -17,   9,  41, -39,  -1, -12, -33,  -5, -38, -30,  -9, -34,  18,  11,   6,  -3,  -4,  -5, -21;
/M: SY='D';  M=  -2, -26,  45,  42, -50, -49, -20, -42,  -8, -24, -26,  32,  22,   7, -21, -10,  -9, -23, -64, -31;
/M: SY='R';  M=  -2, -17, -21, -18, -39, -35, -10,  -8,   7, -22, -24, -43, -35, -19,  72, -19, -20,   1,  34, -28;
/I:         I=-24; MD=-60;
/M: SY='D';  M=  -5, -49,  24,  17, -13,  -4,  22, -35,   5, -25, -26,  -7,   2,  -4, -20, -13, -10, -28, -42, -35; D=-24;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='N';  M= -11, -61,  35,   9, -44, -13,  -2, -65,  26, -58, -28,  38,  18, -11, -10,  15,  -7, -59, -39, -45;
/M: SY='F';  M= -13, -65, -30, -31,  83, -29, -46, -24, -42, -16,  -4, -31, -25, -54, -33, -40, -12, -16, -39,  15;
/M: SY='V';  M=  -8, -36,  -8,  19, -59, -32, -24, -26,  16, -46, -26, -15,  -7,  21,   6, -16,   9,  21, -86, -42;
/M: SY='K';  M= -12, -35, -35,  -2, -21, -42, -22, -36,  52, -36, -25, -22,  29,   2,   5,  -6, -22, -33, -81, -19;
/M: SY='K';  M= -21, -42, -32, -18, -46, -43,  18,  -4,  37, -15,   7, -16, -18,  31,  -5, -30, -38,   8, -82, -12;
/M: SY='P';  M=  -4, -49, -19,  -5, -54, -36, -23, -62,  -6, -69, -64, -31,  89, -38, -24, -20, -17, -48, -55, -74;
/M: SY='G';  M= -24, -65, -18, -19, -55,  55, -26, -60,  19, -41, -37,  13, -41, -31,  -1, -14, -30, -42, -85, -51;
/M: SY='K';  M= -27, -38, -31, -11, -62, -46,  -1, -64,  71, -50, -26, -35, -51,   0,  22, -20, -30, -53, -83, -25;
/M: SY='Y';  M= -27, -84, -25, -44,  36, -63, -37, -41, -38, -27,  14, -62, -45, -42, -42, -38, -16, -18, -43,  91;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_04 which contains 565'928 sequence entries.


Total number of hits 30 in 30 different sequences
Number of true positive hits 30 in 30 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] WGR
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
30 sequences

PARP1_ARATH (Q9ZP54    ), PARP1_BOVIN (P18493    ), PARP1_CAEEL (Q9N4H4    ), 
PARP1_CHICK (P26446    ), PARP1_CRIGR (Q9R152    ), PARP1_HUMAN (P09874    ), 
PARP1_MAIZE (Q9ZSV1    ), PARP1_MOUSE (P11103    ), PARP1_ORYSJ (Q7EYV7    ), 
PARP1_RAT   (P27008    ), PARP1_XENLA (P31669    ), PARP2_ARATH (Q11207    ), 
PARP2_CAEEL (Q09525    ), PARP2_HUMAN (Q9UGN5    ), PARP2_MAIZE (O50017    ), 
PARP2_MOUSE (O88554    ), PARP3_ARATH (Q9FK91    ), PARP3_HUMAN (Q9Y6F1    ), 
PARP3_MEDTR (Q1SGF1    ), PARP3_MOUSE (Q3ULW8    ), PARP3_ORYSJ (Q0E0Q3    ), 
PARP3_SOYBN (Q9SWB4    ), PARP_DROME  (P35875    ), PARP_SARPE  (Q11208    ), 
PRP2A_ORYSJ (Q5Z8Q9    ), PRP2B_ORYSJ (Q0JMY1    ), TNKS1_CAEEL (Q9TXQ1    ), 
Y4DW_SINFN  (P55422    ), YEHF_ECOLI  (P33345    ), YFES_ECOLI  (P78271    )
» more

PDB
[Detailed view]
14 PDB

2CR9; 2EOC; 4DQY; 4OPX; 4OQA; 4OQB; 6F1K; 6F5B; 6F5F; 6USJ; 6X0L; 6X0M; 6X0N; 7AEO
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