PROSITE entry PS51998
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General information about the entry
| Entry name [info] | DEK_C |
| Accession [info] | PS51998 |
| Entry type [info] | MATRIX |
| Date [info] |
03-AUG-2022 CREATED;
03-AUG-2022 DATA UPDATE; 08-NOV-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51998 |
| Associated ProRule [info] | PRU01342 |
Name and characterization of the entry
| Description [info] | DEK C-terminal (DEK-C) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=56; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=51; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3463306; R2=0.0071021; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1360; N_SCORE=12.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=585; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-32; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='E'; M= -1,-106, 20, 37, -32, 8, -30, -42, -18, -9, 31, -5, 36, -18, -22, 15, -24, -24,-110, -74; /M: SY='P'; M= -11, -84, -3, 15, -32, -49, -40, 1, -45, -24, -6, -55, 87, -8, -40, -14, -32, 17,-109, -53; /M: SY='T'; M= -33, -99, 14, -4, -15, -52, -68, -27, -37, -8, -13, -11, -35, -18, -46, 59, 63, -47, -42, -45; /M: SY='D'; M= -40, -51, 70, 51, -88, -71, -32, -51, 22, -40, -42, -7, -7, 12, 12, -18, -17, -28, -64, -98; /M: SY='E'; M= 22,-105, 35, 62, -51, -43, -29, -71, 17, -60, -52, 1, -30, 21, 6, 8, -23, -45,-111, -98; /M: SY='E'; M= -6,-106, 25, 64, -78, -71, -43, -41, 18, -14, -24, -12, -63, 49, 9, -30, 0, -18,-110, -96; /M: SY='I'; M= -69, -31, -65,-108, -22,-101, -84, 71,-106, 56, 15, -83, -87,-102,-106, -79, -90, 20, -98, 26; /M: SY='R'; M= -3, -48, -68, 31, -42,-101, -18, -10, 42, -22, -5, -18, -59, 5, 55, -5, 2, -9, -51, -17; /M: SY='E'; M= 21, -72, 8, 39, -66, -48, -33, -55, 33, -48, -30, 14, 13, 13, 11, 18, 4, -37, -45, -64; /M: SY='A'; M= 38, -46, -13, 35, -36, -43, 10, -18, 23, -40, -37, -32, -60, 1, 13, -1, 32, -24, -23, -53; /M: SY='I'; M= -41, -51, -91,-108, -73, -99, -79, 77,-106, 38, -13,-107, -85,-103, -79, -76, -57, 57,-107, -88; /M: SY='R'; M= -24, -34, 17, 8, -11, -54, -1, -31, 38, -15, -21, -27, -50, 22, 67, -18, -23, -36, -59, -31; /M: SY='E'; M= 13, -57, 41, 58, -74, -44, -11, -62, 20, -64, -44, 4, -67, 25, 10, 15, -23, -52, -34, -54; /M: SY='I'; M= -60, -47,-113, -81, -14,-116,-106, 89,-105, 30, 1,-106,-107, -57, -59,-102, -65, 25, -54, 9; /M: SY='L'; M= -62, -62,-114,-106, -27,-114,-100, 31, -81, 77, 61,-109, -60,-100,-104,-104, -77, 14,-102, -83; /M: SY='R'; M= 24,-104, -2, 15, -69, -38, -6, -82, 41, -46, 19, -16, -35, 31, 47, 11, -9, -48, -47, -63; /M: SY='E'; M= -7, -47, 17, 41,-105, 10, 25, -69, 7, -85, -75, 27, -95, 13, -13, 26, 38, -24,-112, -45; /M: SY='A'; M= 57, -1, -43, -4, -16, -35, -23, -59, -33, -49, -6, -29, -46, 0, -70, 46, -42, 32,-108, -52; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='D'; M= -59,-107, 109, -15,-115, -12, -83,-113, -70,-113,-109, 54, -58, -59, -70, -38, -39, -97,-127,-101; /M: SY='L'; M= -53,-100, -97, -66, 6, -85, -69, -3, -92, 83, 42,-109, -52, -57, -70, -67, -69, -21, -30, -46; /M: SY='E'; M= -14, -73, 54, 65,-107, -71, -25,-104, -17,-102, 31, 32, -74, 20, -47, 28, 4, -84,-113, -51; /M: SY='T'; M= -36, -99, -2, 39, -79, -78, -26, -66, 24, -50, -43, 20, -93, 20, -35, 24, 69, -3,-113, -96; /M: SY='V'; M= -8, -48, -79, -64, -39,-109, -75, 42,-102, 38, 48,-102,-105,-100,-103, -82, 30, 59,-108, -88; /M: SY='T'; M= -79, -92, -87, -71,-100, -63, -94, -93, -52, -97, -49, -43, -91, -87, -93, 65, 104, -70,-116, -96; /M: SY='M'; M= 14, -7, -77, 28, -17, -80, -93, -19, 36, -2, 46, -62, 1, -49, -2, 25, 2, 7,-106, -77; /M: SY='K'; M= -72,-106, -66, -67, -35, -26, -47, -90, 91, -88, -70, -8, -97, -30, 58, -10, -20, -77,-103, -33; /M: SY='Q'; M= -19,-105, 21, -1, -83, -36, -11, -19, 51, -58, 24, -11, -96, 72, -8, 9, 7, -40,-107, -52; /M: SY='V'; M= -28, -48,-113,-108, -29,-114,-110, 68,-106, 17, 12,-107,-107,-104,-107, -87, -66, 75,-108, -87; /M: SY='R'; M= -96, 18, -95, -84, -65,-107, -40, -13, -7, -39, -10, -88,-105, -17, 109, -69, -53, -39,-105, -30; /M: SY='K'; M= -7, -80, -12, 38,-105, -55, -10, -74, 54, -35, -3, 7, -96, 52, 40, -25, 1, -50,-107, -79; /M: SY='Q'; M= 23, -64, -21, 32,-101, -33, 21, -48, 32, -3, 22, -43, -97, 68, 10, -17, -32, -67,-106, -48; /M: SY='L'; M= -6, -41,-113,-106, -75, -86,-101, 8,-106, 80, -3,-110,-111,-101,-105,-101, -90, 34,-104, -64; /M: SY='E'; M= 16, -41, -48, 85, -39, -28, -55, -65, -12, -69, -34, -62, -66, 33, -62, 28, -33, -64,-106, -14; /M: SY='E'; M= 22, -57, 36, 59, -84, -62, -39, -82, 32, -59, -96, -6, -71, 42, -11, 6, -3, -50,-110, -86; /M: SY='K'; M= -19, -81, -2, 33, -40, -83, 45, -41, 53, -20, -13, -35, -78, 17, 47, -34, -26, -28, -25, -5; /M: SY='F'; M= -60, -53, -66, -92, 87, -88, -33, -30,-103, 46, 35, -94, -57, -48, -87,-101, -41, -18, -81, 54; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='G'; M= -24, -48, 40, 2, -88, 56, -24,-107, 19, -71, -43, 46, -30, 13, -21, -3, -22, -57,-111, -71; /M: SY='V'; M= -9, 31, -28, -3, 4, -23, -11, 7, -33, 16, 38, -49, -44, -10, -24, -53, 4, 42,-103, 15; /M: SY='D'; M= -30,-105, 94, 8, -26, -54, -86, -78, -28, -62,-103, 22, -8, -49, -65, 41, -59, -53, -44, -52; /M: SY='L'; M= -57,-100, -72, -26, 17, -57, -56, 7,-102, 75, 41, -44,-109, -30, -80, -60, -59, 2,-100, -44; /M: SY='S'; M= -7, -59, 25, 3, -87, -18, -11, -68, 42, -48, -28, -5, -16, -19, -5, 50, 36, -54,-111, -60; /M: SY='P'; M= -2, -57, 39, 45,-107, -22, 29, -75, -17, -81, -66, 6, 46, 8, -64, 40, -14, -47, -60, -37; /M: SY='H'; M= -96, -33, -91, -30, 6, -77, 71, -55, 43, -71, -48, -48, -74, 27, 69, -44, -82, -54, 6, 58; /M: SY='K'; M= -67,-107, -60, -59,-106, -79, -65, -79, 104, -76, -59, -53, -71, -60, 38, -74, -28, -53, -43, -68; /M: SY='K'; M= 25, -63, 36, 24, -82, -16, -20, -63, 48, -44, -95, -2, -11, 20, -10, 14, -7, -73,-109, -56; /M: SY='F'; M= 2, -84, -30, 39, 72, -93, -39, -30, -30, 3, -1, -71, -58, 8, -47, -42, -18, -14, 32, 34; /M: SY='I'; M= -93,-104,-114, -95, -22,-118,-112, 95, -93, 7, -10, -79,-106,-105,-110, -61, -63, 43,-105, -86; /M: SY='K'; M= -75,-106, 61, -32,-110, -43, -43, -81, 62,-109,-100, 58, -98, -21, 38, 0, -30, -75,-114, -83; /M: SY='E'; M= 18, -84, 30, 54, -79, -15, -4, -81, 11, -70, -51, -1, -95, 40, 11, 9, 7, -71,-111, -57; /M: SY='L'; M= 2, 25, -60, 21, -9, -70, -20, 25, -29, 27, 20, -77, -83, 24, -54, -58, 21, 15, 4, -22; /M: SY='I'; M= -49,-103, -88, -96, -73, -99,-109, 80, -80, 11, 40, -83,-106, -82, -76, -70, -22, 56, -62, -66; /M: SY='M'; M= -35,-105, 49, 33, -48, -36, -22, -17, 17, -6, 50, -12, -79, 29, -2, -16, 9, -36,-110, -45; /M: SY='E'; M= 7,-105, 29, 59, -72, -69, -9, -48, 22, -43, -35, 1, -64, 5, 6, 22, -9, -28,-110, -34; /M: SY='I'; M= 10, 19, -78, 2, 40, -91, -16, 42, -49, -2, -39, -60,-105, -67, 4, -56, -15, 30, -21, 30; /M: SY='L'; M= -66, -49,-113, -74, 32,-114, -71, 35, -94, 63, 51, -66,-110, -68, -74, -71, -56, 19, -98, 2; /M: SY='Q'; M= 10,-105, 31, 34, -49, 2, -14, -55, -10, -29, -41, 29, -98, 35, -12, 7, 10, -31,-112, -50; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 26 in 26 different sequences |
| Number of true positive hits | 26 in 26 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | DEK-C |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
26 sequences
CHS4_CRYNH (J9VF17), CHS5_CRYNH (J9VNT4), CHS6_USTMA (O13395), CHS8_USTMA (Q4P9K9), DEKP1_ARATH (Q9SMM8), DEKP2_ARATH (Q84JB7), DEKP3_ARATH (Q9SUA1), DEKP4_ARATH (F4K4Y5), DEK_HUMAN (P35659), DEK_MOUSE (Q7TNV0), DEK_RAT (Q6AXS3), HMGL_TRYBR (P26586), KELP_ARATH (O65155), MDA3_ARATH (Q9FHX8), SSH1_HUMAN (Q8WYL5), SSH1_MOUSE (Q76I79), SSH2_HUMAN (Q76I76), SSH2_MOUSE (Q5SW75), SSH3_HUMAN (Q8TE77), SSH3_MOUSE (Q8K330), SSH3_RAT(Q5XIS1), SSH_DROME (Q6NN85), SSH_XENLA (Q6IVY4), TRI1_YEAST (Q05024), UAF30_SCHPO (O74503), UAF30_YEAST (Q08747)» more
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| PDB [Detailed view] |
2 PDB
1Q1V; 7Z0O |