We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE entry PS52005
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PURL: https://purl.expasy.org/prosite/signature/PS52005
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General information about the entry
| Entry name [info] | CBM56 |
| Accession [info] | PS52005 |
| Entry type [info] | MATRIX |
| Date [info] |
14-DEC-2022 CREATED;
14-DEC-2022 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52005 |
| Associated ProRule [info] | PRU01349 |
Name and characterization of the entry
| Description [info] | CBM56 (carbohydrate binding type-56) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=89; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=84; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2503402; R2=0.0073436; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=2009; N_SCORE=17.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=579; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M= -40, -72, 30, -58, -67, -21, -18, -11, -60, -37, 58, 46, 42, -21, -65, 38, -9, 9, 5, -23; /M: SY='G'; M= 41, -4, -18, -22, -75, 62, -67, -38, -63, -27, -65, -54, -2, -19, -69, 32, -8, -44, -77, -71; /M: SY='T'; M= -13, 17, 43, -29, -76, 22, -61, -68, -56, -72, -67, 24, 8, 24, -13, 26, 45, -7, -85, -69; /M: SY='S'; M= 32, -69, -61, -7, -17, 31, -66, -32, -61, -32, -63, -55, 34, -17, -67, 46, 40, -38, -77, -67; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='D'; M= 10, -73, 75, -23, -79, 30, -60, -75, -59, -50, -71, 14, 18, -57, -66, 28, 10, -41, -87, -71; /M: SY='F'; M= 19, -17, -25, -19, 70, -44, -6, -30, -67, -4, -53, -30, 27, -66, -69, -6, -59, -12, -54, 61; /M: SY='T'; M= 4, -11, -58, -13, -29, -19, -63, -59, -5, -27, -59, 15, -1, 7, -61, 24, 72, 3, -79, -18; /M: SY='Q'; M= 35, -71, 16, -12, -71, -30, 50, -68, -32, -37, -2, 8, -29, 59, -57, 34, -4, -40, -78, -1; /M: SY='G'; M= 1, 0, -63, -68, -75, 76, -67, -73, -63, -28, -13, -16, -5, -62, -18, 28, 14, -38, -77, -72; /M: SY='V'; M= 36, 27, -8, -64, -14, -41, -68, -9, -65, -25, 5, -6, -7, -15, -69, 10, 14, 50, -78, -12; /I: I=-28; MD=-70; /M: SY='C'; M= -16, 33, -34, -7, -36, -49, -17, -18, -77, -45, -79, -23, -27, -78, -13, -5, 31, -42, -97, -16; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='G'; M= 28, 43, 8, 6, -34, 51, -64, -74, -1, -73, -67, -2, -67, 8, -37, -6, 24, -39, -79, -70; /M: SY='I'; M= 5, 0, -30, -29, -56, -7, 19, 43, -67, 12, -47, -22, 3, -20, -71, -59, 22, 35, -75, 13; /M: SY='S'; M= -4, -69, 12, 22, -74, 4, -59, -33, -54, -49, -64, 33, -65, 34, -60, 51, 40, -15, -83, -68; /M: SY='Q'; M= 18, -73, 29, 13, -77, 25, -6, -16, -55, -46, -64, 4, 13, 52, -61, 21, 12, -43, -80, -68; /M: SY='T'; M= -25, -70, 12, 7, -70, 17, -11, -27, -25, -16, -60, 45, -22, 7, -62, 19, 49, 3, -84, -67; /M: SY='S'; M= -3, -70, 1, 35, -18, 28, -59, -76, -55, -76, -69, 24, -17, 11, -61, 65, 3, -70, -80, -67; /M: SY='A'; M= 49, -68, -1, -63, -65, 19, -69, -7, -65, 18, -53, -60, 1, -19, -70, 14, 9, 14, -78, -66; /M: SY='T'; M= -19, -68, 5, -57, -26, -13, -3, -33, 2, -14, -58, 19, -67, 13, -12, 33, 59, 14, -82, -63; /M: SY='F'; M= -8, -7, -70, -30, 46, -70, -69, 36, -65, 9, -11, -62, -71, -14, -39, 39, 36, -17, 44, -50; /M: SY='W'; M= 21, -73, -77, -21, 27, -73, -71, -13, -68, 17, -7, -73, -75, -6, -70, -40, -1, 33, 107, 26; /M: SY='F'; M= -29, -73, -72, -25, 87, -77, -11, -4, -1, -30, -52, -65, -75, 45, 4, -62, 4, 9, 6, -37; /M: SY='F'; M= 24, -70, -10, -34, 60, -68, -64, -26, 15, -14, -55, -6, 13, -18, -62, -28, 39, -3, -65, 2; /I: I=-26; MD=-67; /M: SY='P'; M= -23, -6, -35, -61, -3, -16, 16, -66, -59, -69, -63, -4, 70, -61, 2, 22, 41, -25, -69, 46; D=-26; /I: I=-26; MD=-67; /M: SY='V'; M= 10, 2, -11, -10, -63, -9, -66, -30, -36, -12, -13, 11, -33, -62, -68, 27, 28, 44, -80, 3; D=-26; /I: I=-26; MD=-67; /M: SY='N'; M= 6, -12, -21, -63, -72, -38, 24, -30, -61, -38, -64, 61, -3, 8, -67, 13, 36, -1, 50, -66; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='T'; M= -1, -71, 16, -16, -77, 17, -1, -72, -29, -75, -68, 28, -2, 1, -24, 47, 47, -36, -85, -69; D=-26; /I: I=-26; DM=-67; /M: SY='A'; M= 60, -67, -61, -7, -75, 6, -67, -69, -22, -39, -65, -22, -15, -57, -65, 42, 39, -60, -81, -71; D=-26; /I: I=-26; DM=-67; /M: SY='D'; M= -2, -72, 49, -51, -78, 17, 22, -75, -54, -55, -68, -9, -22, 25, 15, 42, 38, -69, -85, -67; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='W'; M= -42, -86, -87, -77, 49, -76, -71, 15, -37, -56, -59, -81, -79, -70, -71, -36, -73, -63, 147, 69; /M: SY='V'; M= 61, 27, -76, -70, -62, -67, -78, -4, -70, -49, -50, -71, -74, -69, -73, -54, -52, 76, -83, -66; /I: I=-45; MD=-115; /M: SY='D'; M= -32, -79, 107, -37, -80, -67, -57, 3, -20, -75, -74, -40, -68, -57, -64, -55, 11, -70, -95, -24; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='V'; M= -9, -69, -83, -78, 5, -83, -81, 58, -76, 21, -39, -77, -78, -75, -77, -68, -55, 72, -77, -56; /M: SY='H'; M= -69, -81, -52, -53, -68, -70, 147, -86, -58, -69, -54, -5, -70, -47, -52, -58, -67, -85,-103, -37; /M: SY='Y'; M= -71, -81, -71, -74, 12, -78, -38, -56, -66, -35, -49, -72, -84, -62, -63, -67, -66, -61, -28, 132; /M: SY='K'; M= -57, -72, -59, -51, -72, -68, -59, -17, 49, -43, -60, -17, -66, 41, 49, 31, 49, -11, -78, -64; /M: SY='V'; M= -57, -69, -82, -75, -52, -54, -79, 44, -32, 26, -39, -76, -78, -32, -35, -68, -55, 80, -81, -59; /M: SY='N'; M= -19, -67, -8, -18, -76, -52, -46, -73, -49, -80, -69, 116, -33, -51, -58, -25, 3, -49, -94, -71; /M: SY='G'; M= -26, -73, 13, -64, -81, 80, -60, -84, -61, -84, -74, 65, -34, -60, -69, 11, -58, -80, -81, -75; /M: SY='G'; M= 1, -76, -63, -36, -82, 95, -68, -85, -65, -57, -71, -51, -68, 14, -35, -49, -66, -79, -74, -75; /M: SY='G'; M= 40, -70, -9, -32, -74, 55, -65, -30, -60, -69, -63, 33, -34, -1, -24, -7, -11, 19, -80, -71; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='Q'; M= -60, -82, -56, -13, -19, -69, -49, -69, -18, -13, -2, -52, -68, 124, -42, -51, -62, -72, -71, -58; /M: SY='Q'; M= -33, -77, -61, 1, -65, -72, -54, -54, -50, 37, 28, -28, -71, 102, -25, -56, -24, -27, -72, -24; /M: SY='N'; M= -61, -67, -37, -57, -76, -25, 10, -76, -49, -82, -69, 120, -72, -50, -57, -19, -13, -77, -95, -70; /M: SY='V'; M= -59, -71, -21, -74, -17, -83, -2, 29, -73, 14, -42, -74, -79, -71, -73, -68, -56, 75, -66, 61; /M: SY='R'; M= 11, -77, -63, -54, -23, -70, -54, -73, -33, -47, 1, -28, -73, 9, 99, -11, -4, -68, -74, -19; /M: SY='M'; M= -30, -69, -82, -72, -51, -74, -55, -36, -66, -16, 142, -69, -70, -58, -64, -68, -12, -43, -74, -51; /M: SY='T'; M= 3, -66, -59, -59, -30, -38, -63, -11, -57, -26, -2, 17, -65, 35, -32, 30, 78, -10, -81, -63; /M: SY='W'; M= 13, -75, -14, 0, -27, -67, -3, -2, 14, -37, -57, 25, -13, 29, 1, 4, -57, 8, 53, 49; /M: SY='N'; M= -5, -71, -5, 10, -72, -18, -55, -13, -24, -23, -61, 74, -32, 43, -28, 22, 5, -10, -83, -67; /M: SY='G'; M= 40, -69, -6, -63, -79, 65, -61, -78, -60, -79, -70, 63, -68, -58, -67, 20, -54, -71, -80, -73; /M: SY='G'; M= 6, -71, 6, -21, -78, 72, -63, -78, -61, -78, -6, 32, -18, -59, -68, 29, 12, -72, -80, -73; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='R'; M= -57, -73, -24, 4, -74, 1, -10, -66, -4, -69, 3, 34, -68, 33, 60, 14, 34, 0, -81, -65; /M: SY='W'; M= -69, -81, -68, -71, 36, -69, 15, -34, -64, -63, -63, 62, -35, -65, -68, -65, -29, -20, 139, 47; /M: SY='E'; M= -16, -73, -24, 73, -27, -69, 16, -71, -31, -70, -65, -19, -61, 23, -17, 0, 60, -37, 1, -64; /M: SY='Y'; M= -38, -77, -26, -62, -14, -74, 50, -55, -32, -11, -51, 3, -77, 35, -29, -60, -13, 5, -47, 104; /M: SY='T'; M= -56, -68, -10, 0, -69, -67, -61, -58, -53, -14, -59, 31, 19, 17, 7, 3, 79, 1, -84, -66; /M: SY='V'; M= -21, -70, -78, -76, -25, -7, -78, 55, -71, 4, -42, -23, -76, -72, -22, -64, -7, 70, -79, -60; /M: SY='T'; M= -8, -70, 12, -30, -72, 15, 6, -68, -57, -8, -63, 33, 32, -16, -25, 43, 47, -64, -83, -67; /M: SY='N'; M= -11, -71, -12, -64, -72, 61, -60, -33, -61, -14, -4, 67, -4, -60, -68, 18, -29, -17, -81, -70; /M: SY='L'; M= 7, -70, -77, -33, -25, -42, -68, -39, -70, 74, 1, -75, 16, -66, -27, -17, -60, -11, -73, -57; /M: SY='S'; M= 23, -67, -58, -28, -73, 9, -62, -29, 26, -70, -64, 15, -66, -4, -56, 69, -5, 3, -80, -67; /M: SY='A'; M= 45, -68, 23, -12, -75, 27, -63, -36, -59, -70, -65, 13, -32, 13, -64, 41, 0, 0, -81, -69; /M: SY='G'; M= -7, -74, 8, -65, -26, 84, 2, -75, -65, -76, -69, 5, -69, 10, -70, -50, -12, -7, -77, -70; /M: SY='D'; M= -24, -75, 92, 5, -79, -65, -58, -32, -31, -74, -71, -15, -11, 0, -62, 3, 39, -20, -92, -69; /M: SY='V'; M= -22, -69, -69, -32, -59, -75, -70, 24, -60, 3, -47, -1, -72, 0, 20, -19, 41, 63, -82, -62; /I: I=-38; MD=-97; /M: SY='V'; M= -68, -81, -93, -89, -60, -96, -91, 58, -86, -7, -49, -87, -87, -85, -87, -78, -27, 65, -88, -13; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='D'; M= -35, -73, 59, 29, -1, -65, -56, -68, -51, -70, -66, 17, -67, 0, 21, 39, 21, -6, -78, 7; /M: SY='Y'; M= -71, -80, -71, -73, 36, -76, 4, -33, -66, -53, -51, -17, -82, -63, -64, -34, -65, -61, 48, 123; /M: SY='W'; M= -61, -74, -68, -67, 68, -68, -1, -25, -59, -58, -59, 4, -75, -27, 18, 48, -5, -62, 86, 53; /M: SY='F'; M= -71, -1, -81, -79, 109, -81, -64, -49, -74, -25, -51, -72, -82, -81, -73, -67, 25, -28, -44, 41; /M: SY='T'; M= -55, -65, 1, -61, -60, -69, -66, -10, -59, -61, -59, -50, -62, -62, -66, -13, 103, -29, 46, 25; /M: SY='Y'; M= -68, -80, -6, -71, -27, -41, -45, 17, -38, -12, -48, -70, -81, -63, -65, -66, -63, -5, -37, 120; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='W'; M= -23, -78, -24, 46, -27, -45, -58, 11, -53, -12, -9, 45, -1, 66, -58, -56, -26, -31, 78, -59; /M: SY='N'; M= -7, -73, 36, -24, -12, -64, -14, -25, 37, -45, -64, 47, 17, 38, -7, -1, 26, -66, -80, -64; /M: SY='G'; M= 7, 22, 16, -12, -77, 52, -60, -74, -22, -50, -68, 52, -26, -12, -28, 12, 15, -40, -82, -72; /M: SY='G'; M= -3, -71, -24, -36, -77, 76, -63, -77, -33, -50, -69, 48, -67, -60, -68, 12, 17, -45, -79, -73; /I: I=-45; MD=-115; /M: SY='C'; M= -11, 45, -70, -67, -25, 29, -69, -52, -6, 18, -54, -29, 39, -11, -68, -13, 10, 27, -77, -10; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='A'; M= 69, -67, -64, -57, -75, 24, -65, -23, -58, -66, -60, -9, -67, 58, -62, -45, 10, -2, -77, -69; /M: SY='Y'; M= -34, 14, -30, 5, -39, -75, 6, -54, -12, -14, -5, -19, -76, -4, 0, -38, -9, 14, -49, 100; /M: SY='D'; M= -3, -77, 103, 9, -83, -65, -56, -75, -54, -77, -74, -41, -66, 26, -61, -52, 10, -20, -94, -69; /M: SY='T'; M= -17, -64, -7, -25, -68, -64, -64, -28, -57, -65, -61, -9, -62, -58, -30, 42, 93, -16, -84, -25; /M: SY='D'; M= 35, -73, 41, 36, -80, 13, -61, -75, -54, -76, -69, -19, 36, 6, -20, 21, 15, -68, -82, -71; /M: SY='W'; M= -15, -79, -71, -33, -57, -18, 18, -69, -62, -44, -66, -28, 28, -62, -25, 7, 53, -70, 138, -46; /M: SY='Y'; M= 18, -73, -64, 12, 28, -36, -56, -57, -32, 7, -54, -63, 17, 21, -24, 12, -7, -16, -58, 68; /M: SY='T'; M= -17, -69, -57, -53, -25, -26, 4, -68, -51, -69, -62, 10, -64, 63, 3, 43, 73, -63, 13, -61; /M: SY='Y'; M= 2, -77, -69, -67, 51, -72, 58, -60, -29, -40, -53, -64, -77, 4, -61, -22, -12, -62, 45, 100; /M: SY='T'; M= -24, -66, -61, -61, -63, -68, -3, -9, -56, -60, -57, -17, -65, -9, 10, 22, 87, 22, -81, 3; /M: SY='H'; M= -64, -4, -71, -68, 55, -76, 71, -26, -40, -11, -4, -64, -26, -30, -12, -1, -33, 32, -58, 66; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 1 |
| Number of true positive hits | 1 |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CBM56 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
1 sequence
ENG1_HALH5 (Q9KG76)
|
| PDB [Detailed view] |
1 PDB
pdb_00005t7a |